Specialty Imaging: HRCT of the Lung
- 3rd Edition - July 30, 2025
- Latest edition
- Authors: Santiago Martínez-Jiménez, Melissa L. Rosado-de-Christenson, Sherief Garrana
- Language: English
Part of the highly regarded Specialty Imaging series, HRCT of the Lung, third edition, reflects the many recent changes in HRCT diagnostic interpretation. An easy-to-read… Read more
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Part of the highly regarded Specialty Imaging series, HRCT of the Lung, third edition, reflects the many recent changes in HRCT diagnostic interpretation. An easy-to-read bulleted format and thousands of state-of-the-art imaging examples guide you step by step through every aspect of thin-section CT and HRCT in the evaluation of patients with suspected lung disease. This book is an ideal resource for radiologists and internal medicine specialists who need an easily accessible tool to help them understand the indications, strengths, and limitations of HRCT in their practice.
- Helps you identify and characterize critical HRCT findings and gain a solid understanding of cross-sectional imaging anatomy of the lung—crucial skills for formulating diagnoses and appropriate differential diagnoses
- Delivers details on anatomy-based exploration as well as nodules and micronodules, cysts and pseudocysts, reticulation and honeycombing, mosaic attenuation, ground-glass opacities, and interlobular septal thickening
- Uses a time-saving, bulleted format that distills essential information for fast and easy comprehension
- Includes new chapters on post-COVID-19 findings, respiratory syncytial virus, and e-cigarette and vaping product use-associated lung injury (EVALI), as well as content on new morphologic patterns for pulmonary fibrosis, the new classification for hypersensitivity pneumonia, and more
- Provides direction for determining common, less common, and rare diagnoses based on morphologic features, distribution of abnormalities, and/or histologic patterns
- Features superb illustrations with comprehensive captions that display both typical and variant findings on HRCT scans
- Offers new references, new images, and new histopathologic correlations throughout
- Includes an eBook version that allows you to access everything in this print version as well as additional images, text, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud; additional digital ancillary content may publish up to 6 weeks following the publication date
Cardiothoracic radiologists, including residents and fellows, as well as pulmonologists and rheumatologists at all levels of training
SECTION 1: FUNDAMENTALS OF HRCT
Overview of HRCT
Approach to HRCT Interpretation
ANATOMY
Interstitial Compartments
Secondary Pulmonary Lobule
Gravitational Changes (Dependent Atelectasis)
Age-Related Changes
Normal Inspiration and Expiration
TERMINOLOGY AND SIGNS
3-Density Sign (Formerly Head Cheese Sign)
Airspace Nodules
Anterior Upper Lobe Sign
Crazy Paving
Cystic Lung Disease
Exuberant Honeycombing
Finger-in-Glove Sign
Flame-Shaped Nodules
Four Corners Sign
Ground Glass
Halo Sign
Honeycombing (Peribronchovascular)
Honeycombing (Subpleural)
Honeycombing (Unilateral)
Micronodules
Mosaic Attenuation and Air-Trapping
Reversed Halo Sign
Signet-Ring Sign
Straight-Edge Sign
Tree-in-Bud Opacities
Thick-Walled Cystic Lesions (Stalactite and Stalagmite Sign)
DISTRIBUTION
Peribronchovascular
Centrilobular
Perilymphatic
Random
Peripheral
SECTION 2: PATHOLOGIC PATTERNS OF INJURY
Approach to Pathologic Patterns of Injury
Diffuse Alveolar Damage
Diffuse Alveolar Hemorrhage With Capillaritis
Organizing Pneumonia
Constrictive Bronchiolitis
SECTION 3: LARGE AIRWAYS DISEASE
Approach to Large Airways Disease
Bronchiectasis
Allergic Bronchopulmonary Aspergillosis
Williams-Campbell Syndrome
Mounier-Kuhn Syndrome
Bronchocentric Granulomatosis
SECTION 4: SMALL AIRWAYS DISEASE
Approach to Small Airways Disease
Infectious Bronchiolitis
Asthma
Diffuse Aspiration Bronchiolitis
Respiratory Bronchiolitis
Follicular Bronchiolitis
Hypersensitivity Pneumonitis
Diffuse Panbronchiolitis
Idiopathic Constrictive Bronchiolitis
Swyer-James-MacLeod Syndrome
Bronchiolitis Obliterans Syndrome
Diffuse Idiopathic Pulmonary Neuroendocrine Cell
Hyperplasia (DIPNECH)
SECTION 5: INFECTION
Approach to Infection
Bacterial Pneumonia
Mycoplasma Pneumonia
Staphylococcus aureus Pneumonia
Viral Pneumonia
Influenza
COVID-19
Respiratory Syncytial Virus
Cytomegalovirus
Tuberculosis
Nontuberculous Mycobacterial Infection
Endemic Fungal Infection
Cryptococcosis
Aspergillosis
Pneumocystis Pneumonia
Candidiasis
SECTION 6: PNEUMOCONIOSIS
Approach to Pneumoconiosis
Silicosis and Coal Worker's Pneumoconiosis
Asbestosis
Berylliosis
Talcosis
Hard Metal Lung Disease
SECTION 7: NEOPLASMS
Approach to Neoplasms
Invasive Mucinous Adenocarcinoma (Diffuse)
Diffuse and Multifocal Lung Cancer
Lymphangitic Carcinomatosis
Hematogenous Metastases
Endovascular Metastases and Tumor Emboli
Kaposi Sarcoma
Lymphangioleiomyomatosis
Reactive Lymphoproliferative Disorders
Neoplastic Lymphoproliferative Disorders
Pulmonary Langerhans Cell Histiocytosis
Erdheim-Chester Disease
Rosai-Dorfman Disease
Diffuse Pulmonary Meningotheliomatosis (DPM)
SECTION 8: INTERSTITIAL PNEUMONIAS
Approach to Interstitial Pneumonias
Interstitial Lung Abnormality (ILA)
Idiopathic Pulmonary Fibrosis
Progressive Pulmonary Fibrosis (PPF)
Idiopathic Nonspecific Interstitial Pneumonia
Cryptogenic Organizing Pneumonia
Acute Exacerbation of Interstitial Lung Disease
Acute Interstitial Pneumonia
Idiopathic Lymphoid Interstitial Pneumonia
Pleuroparenchymal Fibroelastosis
Airway-Centered Interstitial Fibrosis
Interstitial Pneumonia With Autoimmune Features (IPAF)
Approach to Smoking-Related Interstitial Lung Diseases
Respiratory Bronchiolitis-Interstitial Lung Disease
Desquamative Interstitial Pneumonia
Syndrome of Combined Pulmonary Fibrosis and Emphysema
Smoking-Related Interstitial Fibrosis (SRIF)
Airspace Enlargement With Fibrosis (AEF)
SECTION 9: AUTOIMMUNE DISEASES
Approach to Connective Tissue Disease-Associated Interstitial Lung Disease
Rheumatoid Arthritis
Progressive Systemic Sclerosis
Idiopathic Inflammatory Myopathies
Sjögren Syndrome
Mixed Connective Tissue Disease
Systemic Lupus Erythematosus
Granulomatosis With Polyangiitis (GPA)
Eosinophilic Granulomatosis With Polyangiitis
Microscopic Polyangiitis
Ankylosing Spondylitis
Inflammatory Bowel Disease-Associated Lung Disease
SECTION 10: VASCULAR DISEASE
Approach to Vascular Disease
Pulmonary Edema
Hepatopulmonary Syndrome
Pulmonary Hypertension
Pulmonary Venoocclusive Disease/Pulmonary
Capillary Hemangiomatosis
Excipient Lung Disease (Talc/Cellulose Granulomatosis)
Chronic Thromboembolic Pulmonary Hypertension
SECTION 11: INHALATIONAL, INFLAMMATORY, METABOLIC, AND POST TREATMENT
Approach to Inhalational, Inflammatory, Metabolic, and Post Treatment
ASPIRATION/INHALATION
Spectrum of Aspiration-Related Disorders
Lipoid Pneumonia
Inhalational Lung Injury
E-Cigarette or Vaping Product Use-Associated Lung Injury (EVALI)
Recurrent Gastric Acid Aspiration and Dendriform
Pulmonary Ossification
INFLAMMATORY
Sarcoidosis
Acute Eosinophilic Pneumonia
Chronic Eosinophilic Pneumonia
Other Eosinophilic Disorders
METABOLIC OR DEGENERATIVE
Amyloidosis
Light Chain Deposition Disease
Pulmonary Alveolar Proteinosis
Metastatic Pulmonary Calcification
Diffuse Pulmonary Ossification
Emphysema
Idiopathic Pulmonary Hemosiderosis
POST TREATMENT
Radiation-Induced Lung Disease
Drug-Induced Lung Disease
Immune Checkpoint Inhibitor-Related Pneumonitis
SECTION 12: CONGENITAL
Approach to Congenital
Familial Idiopathic Pulmonary Fibrosis
Birt-Hogg-Dubé Syndrome
Hermansky-Pudlak Syndrome
Tuberous Sclerosis Complex
Neurofibromatosis
Alveolar Microlithiasis
α-1 Antitrypsin Deficiency
Primary Ciliary Dyskinesia
Chronic Granulomatous Disease
Common Variable Immunodeficiency
Primary Immunodeficiency Disorders
Cystic Fibrosis
Childhood Interstitial Lung Disease (chILD)
Diffuse Pulmonary Lymphangiomatosis
Proximal Interruption of Pulmonary Artery
Overview of HRCT
Approach to HRCT Interpretation
ANATOMY
Interstitial Compartments
Secondary Pulmonary Lobule
Gravitational Changes (Dependent Atelectasis)
Age-Related Changes
Normal Inspiration and Expiration
TERMINOLOGY AND SIGNS
3-Density Sign (Formerly Head Cheese Sign)
Airspace Nodules
Anterior Upper Lobe Sign
Crazy Paving
Cystic Lung Disease
Exuberant Honeycombing
Finger-in-Glove Sign
Flame-Shaped Nodules
Four Corners Sign
Ground Glass
Halo Sign
Honeycombing (Peribronchovascular)
Honeycombing (Subpleural)
Honeycombing (Unilateral)
Micronodules
Mosaic Attenuation and Air-Trapping
Reversed Halo Sign
Signet-Ring Sign
Straight-Edge Sign
Tree-in-Bud Opacities
Thick-Walled Cystic Lesions (Stalactite and Stalagmite Sign)
DISTRIBUTION
Peribronchovascular
Centrilobular
Perilymphatic
Random
Peripheral
SECTION 2: PATHOLOGIC PATTERNS OF INJURY
Approach to Pathologic Patterns of Injury
Diffuse Alveolar Damage
Diffuse Alveolar Hemorrhage With Capillaritis
Organizing Pneumonia
Constrictive Bronchiolitis
SECTION 3: LARGE AIRWAYS DISEASE
Approach to Large Airways Disease
Bronchiectasis
Allergic Bronchopulmonary Aspergillosis
Williams-Campbell Syndrome
Mounier-Kuhn Syndrome
Bronchocentric Granulomatosis
SECTION 4: SMALL AIRWAYS DISEASE
Approach to Small Airways Disease
Infectious Bronchiolitis
Asthma
Diffuse Aspiration Bronchiolitis
Respiratory Bronchiolitis
Follicular Bronchiolitis
Hypersensitivity Pneumonitis
Diffuse Panbronchiolitis
Idiopathic Constrictive Bronchiolitis
Swyer-James-MacLeod Syndrome
Bronchiolitis Obliterans Syndrome
Diffuse Idiopathic Pulmonary Neuroendocrine Cell
Hyperplasia (DIPNECH)
SECTION 5: INFECTION
Approach to Infection
Bacterial Pneumonia
Mycoplasma Pneumonia
Staphylococcus aureus Pneumonia
Viral Pneumonia
Influenza
COVID-19
Respiratory Syncytial Virus
Cytomegalovirus
Tuberculosis
Nontuberculous Mycobacterial Infection
Endemic Fungal Infection
Cryptococcosis
Aspergillosis
Pneumocystis Pneumonia
Candidiasis
SECTION 6: PNEUMOCONIOSIS
Approach to Pneumoconiosis
Silicosis and Coal Worker's Pneumoconiosis
Asbestosis
Berylliosis
Talcosis
Hard Metal Lung Disease
SECTION 7: NEOPLASMS
Approach to Neoplasms
Invasive Mucinous Adenocarcinoma (Diffuse)
Diffuse and Multifocal Lung Cancer
Lymphangitic Carcinomatosis
Hematogenous Metastases
Endovascular Metastases and Tumor Emboli
Kaposi Sarcoma
Lymphangioleiomyomatosis
Reactive Lymphoproliferative Disorders
Neoplastic Lymphoproliferative Disorders
Pulmonary Langerhans Cell Histiocytosis
Erdheim-Chester Disease
Rosai-Dorfman Disease
Diffuse Pulmonary Meningotheliomatosis (DPM)
SECTION 8: INTERSTITIAL PNEUMONIAS
Approach to Interstitial Pneumonias
Interstitial Lung Abnormality (ILA)
Idiopathic Pulmonary Fibrosis
Progressive Pulmonary Fibrosis (PPF)
Idiopathic Nonspecific Interstitial Pneumonia
Cryptogenic Organizing Pneumonia
Acute Exacerbation of Interstitial Lung Disease
Acute Interstitial Pneumonia
Idiopathic Lymphoid Interstitial Pneumonia
Pleuroparenchymal Fibroelastosis
Airway-Centered Interstitial Fibrosis
Interstitial Pneumonia With Autoimmune Features (IPAF)
Approach to Smoking-Related Interstitial Lung Diseases
Respiratory Bronchiolitis-Interstitial Lung Disease
Desquamative Interstitial Pneumonia
Syndrome of Combined Pulmonary Fibrosis and Emphysema
Smoking-Related Interstitial Fibrosis (SRIF)
Airspace Enlargement With Fibrosis (AEF)
SECTION 9: AUTOIMMUNE DISEASES
Approach to Connective Tissue Disease-Associated Interstitial Lung Disease
Rheumatoid Arthritis
Progressive Systemic Sclerosis
Idiopathic Inflammatory Myopathies
Sjögren Syndrome
Mixed Connective Tissue Disease
Systemic Lupus Erythematosus
Granulomatosis With Polyangiitis (GPA)
Eosinophilic Granulomatosis With Polyangiitis
Microscopic Polyangiitis
Ankylosing Spondylitis
Inflammatory Bowel Disease-Associated Lung Disease
SECTION 10: VASCULAR DISEASE
Approach to Vascular Disease
Pulmonary Edema
Hepatopulmonary Syndrome
Pulmonary Hypertension
Pulmonary Venoocclusive Disease/Pulmonary
Capillary Hemangiomatosis
Excipient Lung Disease (Talc/Cellulose Granulomatosis)
Chronic Thromboembolic Pulmonary Hypertension
SECTION 11: INHALATIONAL, INFLAMMATORY, METABOLIC, AND POST TREATMENT
Approach to Inhalational, Inflammatory, Metabolic, and Post Treatment
ASPIRATION/INHALATION
Spectrum of Aspiration-Related Disorders
Lipoid Pneumonia
Inhalational Lung Injury
E-Cigarette or Vaping Product Use-Associated Lung Injury (EVALI)
Recurrent Gastric Acid Aspiration and Dendriform
Pulmonary Ossification
INFLAMMATORY
Sarcoidosis
Acute Eosinophilic Pneumonia
Chronic Eosinophilic Pneumonia
Other Eosinophilic Disorders
METABOLIC OR DEGENERATIVE
Amyloidosis
Light Chain Deposition Disease
Pulmonary Alveolar Proteinosis
Metastatic Pulmonary Calcification
Diffuse Pulmonary Ossification
Emphysema
Idiopathic Pulmonary Hemosiderosis
POST TREATMENT
Radiation-Induced Lung Disease
Drug-Induced Lung Disease
Immune Checkpoint Inhibitor-Related Pneumonitis
SECTION 12: CONGENITAL
Approach to Congenital
Familial Idiopathic Pulmonary Fibrosis
Birt-Hogg-Dubé Syndrome
Hermansky-Pudlak Syndrome
Tuberous Sclerosis Complex
Neurofibromatosis
Alveolar Microlithiasis
α-1 Antitrypsin Deficiency
Primary Ciliary Dyskinesia
Chronic Granulomatous Disease
Common Variable Immunodeficiency
Primary Immunodeficiency Disorders
Cystic Fibrosis
Childhood Interstitial Lung Disease (chILD)
Diffuse Pulmonary Lymphangiomatosis
Proximal Interruption of Pulmonary Artery
- Edition: 3
- Latest edition
- Published: July 30, 2025
- Language: English
SM
Santiago Martínez-Jiménez
Dr. Santiago Martínez-Jiménez is with the Department of Radiology at Saint Luke's Hospital of Kansas City and is Professor of Radiology at the University of Missouri-Kansas City School of Medicine, in Kansas City, Missouri. He’s a board-certified practicing radiologist who specializes in cardiothoracic radiology
Affiliations and expertise
Department of Radiology, Saint Luke's Hospital of Kansas City, Professor of Radiology, University of Missouri-Kansas City School of Medicine, Kansas City, Missouri, USAMR
Melissa L. Rosado-de-Christenson
Melissa L. Rosado-de-Christenson, MD, FACR, FAAWR, is Attending Radiologist at the Division of Cardiothoracic Imaging in the Department of Medical Imaging for Banner – University Medical Group Tucson,. She is also Professor of Medical Imaging at University of Arizona College of Medicine – Tucson, in Tucson, Arizona
Affiliations and expertise
Melissa L. Rosado-de-Christenson, MD, FACR, FAAWR, Attending Radiologist, Division of Cardiothoracic Imaging, Department of Medical Imaging, Banner – University Medical Group Tucson, Professor of Medical Imaging, University of Arizona College of Medicine – Tucson, Tucson, Arizona, USASG
Sherief Garrana
Sherief H. Garrana, MD, is a clinical assistant professor of radiology with the Division of Thoracic Imaging in the Department of Radiology at NYU Langone Health in New York, New York.
Affiliations and expertise
Clinical Assistant Professor of Radiology, Division of Thoracic Imaging, Department of Radiology, NYU Langone Health, New York, NY, USA