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Sex and Cardiac Electrophysiology

Differences in Cardiac Electrical Disorders Between Men and Women

  • 1st Edition - July 10, 2020
  • Latest edition
  • Editor: Marek Malik
  • Language: English

Sex and Cardiac Electrophysiology: Differences in Cardiac Electrical Disorders Between Men and Women is a comprehensive investigation into all aspects of sex differences in cardia… Read more

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Description

Sex and Cardiac Electrophysiology: Differences in Cardiac Electrical Disorders Between Men and Women is a comprehensive investigation into all aspects of sex differences in cardiac electrophysiology. As there are substantial differences between female and male patients in physiology, pathology triggering factors, disease progression, clinical approaches and treatment outcome, this book provides a comprehensive examination. In cardiology, the differences between women and men are more recognized, hence this title summarizes these important differences, providing the essential information needed for clinical specialists and researchers involved in the design and implementation of clinical studies.

Key features

  • Explores topics ranging from the physiologic differences between women and men to the differences in clinical handling of arrhythmic disorders between female and male patients
  • Provides sex differences in cardiac electrophysiology in separate chapters
  • Covers the sex differences of cardiac electrical disorders, providing insights beyond cardiac metabolic syndrome, hypertension, atherogenesis and heart failure

Readership

research specialists (in both academia and medical industry) involved in setting up clinical studies and trials in cardiac electrophysiology; physicians specialising in cardiac electrophysiology; general cardiologists and other medical specialists and general practitioners who treat patients with cardiac problems

Table of contents

Foreword
Hein JJ Wellens
Preface
Marek Malik

Introduction

1. Distinction between sex and gender
Marek Malik

2. What is sex good for?
Thomas Brand

Cellular and Tissue Electrophysiology

3. Sex differences in cardiac ion channels
Wendy Wu

4. Atrial and ventricular tissue electrophysiology
Ksenia Blinova

5. Cardiac conduction system
Elena Efimova

Electrocardiography

6. Morphology of normal resting electrocardiogram
Peter Wilson Macfarlane and Pamela Armstrong

7. QRS duration
Katerina Hnatkova

8. Sex differences in QRS fractionation and slurring abnormalities
Tuomas Kenttä

9. QT interval and QT/RR relationship
Larisa Tereshchenko

11. T wave morphology and ventricular gradient
Katerina Hnatkova

12. T wave alternans
Richard L. Verrier

13. Sex-specific definitions of electrocardiographic abnormalities
Alan Kadish and Jason Jacobson

Cardiac Autonomic Regulation

14. Baseline autonomic characteristics
Olivia Manfrini

15. Cardiac autonomic responses to provocative stimuli
Katerina Hnatkova

16. Circadian pattern of autonomic status
Phyllis Kravet Stein

Effects of Sex Hormones

17. Electrophysiological cellular effects of sex hormones
Markéta Bébarová

18. Development of electrocardiographic sex differences during puberty
Irena Andrsova

19. Electrophysiologic changes during menstrual cycle
Mehmet Dogan

20. Electrocardiographic changes after heart transplantation
Tomas Novotny

21. Cardiac rhythm changes during menopause
Mihail Gabriel Chelu

Channelopathies

22. Congenital long QT syndrome
Elizabeth S. Kaufman

23. Congenital short QT syndrome
Preben Bjerregaard

24. Brugada syndrome
Anat Milman

Drug-Induced Electrophysiology Abnormalities

25. Mechanisms of drug-induced QT interval prolongation
Gopi Krishna Panicker

26. Mechanisms and incidence of Torsade de Pointes tachycardia
Tomas Novotny

Training and Sport

27. Electrophysiological adaptations to endurance and strength training
Laura Karavirta

28. Exercise-based cardiac rehabilitation
Arto J. Hautala

29. Arrhythmias due to athletic training
Sanjay Sharma and Hamish MacLachlan

Cardiomyopathies and Inherited Disorders

30. Hypertrophic cardiomyopathy
Kathleen Stergiopoulos

31. Dilated cardiomyopathy
Brian Halliday

32. Arrhythmogenic right ventricular cardiomyopathy
Cynthia James

33. Catecholaminergic polymorphic ventricular tachycardia
Kristina H Haugaa

34. Cardiac electrophysiology in sex chromosome aneuploidies
James Turner and Benjamin Powell

35. Takotsubo syndrome
Birke Schneider

Supraventricular Tachycardias

36. Supraventricular ectopies
Emanuela Teresa Locati

37. Focal supraventricular tachycardia
Shih-Ann Chen

38. Accessory pathway and atrio-ventricular reentrant tachycardia
Martina Sisakova

39. Atrioventricular nodal reentrant tachycardia
Thomas Jared Bunch

40. Inappropriate sinus tachycardia
Lee Eckhardt

41. Ablation of nodal and atrio-ventricular accessory pathways
Abhishek Deshmukh

Atrial Fibrillation

42. Rate control of atrial fibrillation
Isabelle C. Van Gelder and Mariëlle Kloosterman

43. Cardioversion
Juha EK Hartikainen

44. Catheter ablation of atrial fibrillation
Ondrej Toman

45. Demographics and procedural data differences of AF ablation
Elisabetta Toso

46. Monitoring and follow-up after atrial fibrillation ablation
Tatjana Potpara

47. Thromboembolic risk and anticoagulation therapy
Gregory Y H Lip

48. Quality of life with AF
Carina Blomström-Lundqvist

Myocardial Ischemia and Infarction

49. Electrocardiographic manifestation of suspected acute coronary syndromes
Jessica K. Zègre-Hemsey

50. Acute MI and cardiogenic shock arrhythmias
Martina Sisakova

51. Arrhythmias of subacute phase of MI
Raffaele Bugiardini

52. Sex-specific arrhythmia risk of post-MI follow-up
Petra Barthel

53. Sex Differences in Intensive Care Unit Electrocardiographic Alarms
Michele M. Pelter

54. Predictive value of admission electrocardiography in heart failure
Thomas Klingenheben

Ventricular Tachycardias

55. Ventricular arrhythmias associated with structural heart disease
Ljuba Bacharova

56. Catheter ablation of ventricular arrhythmias associated with structural heart disease
Sabine Ernst

57. Idiopathic ventricular arrhythmias
Hiroshi Tada

58. Mapping and catheter ablation of idiopathic ventricular arrhythmias
Andrea Sarkozy and Francesco Raffaele Spera

Electrophysiology in Pregnancy

59. Hormonal and autonomic electrophysiologic effects of pregnancy
Cynthia Tracy and Saima Karim

60. Supraventricular tachycardias during pregnancy
Vaibhav Vaidya

61. Atrial fibrillation during pregnancy
Georgios Georgiopoulos

62. Ventricular tachyarrhythmia during pregnancy
Georgios Georgiopoulos

63. Pregnancy in congenital long QT and Brugada syndrome patients
Danna A. Spears

64. Pregnancy and implanted devices
Stephanie Curtis

65. Fetal arrhythmia in intrahepatic cholestasis of pregnancy
Catherine Williamson

Sudden Cardiac Death

66. Demographics and epidemiology
Iwona Cygankiewicz

67. Sudden Infant death syndrome
Jennifer N.A. Silva and Aarti Dalal

68. Cardiac risk in the young
Maria Cecilia Gonzalez Corcia

69. Sex-specific mechanisms of sudden cardiac death
Rachel Lampert

70. Sex-specific risk assessment of sudden cardiac death
Kristen K. Patton

Drug Therapy

71. Safety and efficacy of antiarrhythmic drugs
Isabelle C. Van Gelder and Mariëlle Kloosterman

72. Dose responses in acquired long QT syndrome
Christine Garnett

73. Acquired long QT syndrome and sex hormones
Katja E Odening

74. Management of arrhythmias in pregnancy
Carina Blomström-Lundqvist

Device Based Therapies

75. Antibradycardia pacing
Anne B. Curtis and Hiroko Beck

76. Primary and secondary prevention of SCD in women
Ulrika Birgersdotter-Green and Emma Svennberg

77. Utility of Implantable cardioverter-defibrillators
Anne Gillis

78. ICD registries and sex-specific metanalyses
Markus Zabel

79. Clinical experience with the use of CRT in women
Valentina Kutyifa

80. CRT registries and sex-specific metanalyses
Mordechai Haim

81. Lead extraction in women
Maria Grazia Bongiorni

82. Quality of life with implanted devices
Cecilia M. Linde

Outlook

83. Obstacles for enrolment of women in clinical trials
Christian Sticherling

84. Regulatory implications of sex differences in clinical trials
Libet Garber and Helen Jiang

Product details

  • Edition: 1
  • Latest edition
  • Published: July 11, 2020
  • Language: English

About the editor

MM

Marek Malik

Marek Malik, PhD, MD, graduated from both mathematics and medicine and obtained Doctor of Science degrees in both disciplines (at Charles University in Prague and at University of London). He is Professor of Cardiac Electrophysiology and presently serves as a Senior Research Investigator at National Heart and Lund Institute of Imperial College, London. His research interests include autonomic nervous system, computerized electrocardiography, electrophysiologic responses to autonomic provocations, and cardiovascular risk assessment. In these fields, he authored many peer-review publications and served in a number of task forces including the chairmanship of the task forces providing the standards of heart rate variability and of assessment of drug-induced repolarization changes.
Affiliations and expertise
Senior Research Investigator/Professor of Cardiac Electrophysiology, Imperial College, UK

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