
Sabiston Textbook of Surgery
The Biological Basis of Modern Surgical Practice
- 22nd Edition - June 1, 2025
- Imprint: Elsevier
- Editor: Douglas Scott Tyler
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 3 7 9 1 6 - 1
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 1 2 4 3 4 - 1
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 2 4 3 5 - 8
For generations of trainees and surgeons at all levels of experience, Sabiston Textbook of Surgery: The Biological Basis of Modern Surgical Practice has been the go-to text for… Read more

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Request a sales quoteFor generations of trainees and surgeons at all levels of experience, Sabiston Textbook of Surgery: The Biological Basis of Modern Surgical Practice has been the go-to text for definitive guidance on every aspect of general surgery. As the oldest continuously published textbook of surgery in North America, the fully revised 22nd Edition continues to provide the key information, essential teaching pearls, and updated content needed to make the most informed surgical decisions and achieve optimal outcomes for patients. Concisely written and evidence-based throughout, it covers the breadth of material required for certification and practice of general surgery, highlighted by detailed, full-color intraoperative illustrations and high-quality video clips.
- Provides detailed, practical answers and quickly accessible clinical content for surgeons at all levels, across all subspecialties—offering a one-stop, complete reference throughout a surgeon’s career, including information needed for residency and board certification.
- Contains new chapters on minimally invasive surgery, endoscopic techniques, simulation, and AI, as well as expanded discussions of robotic and minimally invasive approaches to surgical procedures.
- Follows a clear, consistent progression beginning with principles common to surgical specialties including fluid and electrolyte management, metabolic support, and wound healing; subsequent sections review the management of injury, transplantation, oncology, breast, endocrine, and abdominal procedures.
- Presents the underlying science and its clinical application to make informed surgical decisions and achieve optimal outcomes.
- Covers topics encountered by general surgery residents in training as well as in-depth coverage of subspecialty areas including head and neck, thoracic, vascular, urology, neurosurgery, pediatrics, and gynecology.
- Provides access to more than two dozen high-quality surgical procedure and technique videos (many are new!), new podcast-style audio resources, more than 2,000 superb images, and hundreds of quick-reference tables, boxes, and algorithms.
- Shares the fresh perspectives and expertise of new lead editor Dr. Douglas S. Tyler, and six new associate editors, Drs. Andrea Hayes-Dixon, O. Joe Hines, Rachel Kelz, Melina R. Kibbe, Christine Lau, and Mayur Patel.
- An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date.
General surgeons in training and in practice
Section 1 Surgical Training and Quality Control
1. Surgical Education Past, Present and Future
2. Surgical Simulation and new ways to optimize performance
3. Certification of Surgeon Competence
4. Preoperative Risk Assessment and Alterations in the COVID Era
5. Social Determinants of Health and Their Impact on Surgical Outcomes
6. Critical Assessment of Surgical Outcomes and Health Service Research
7. Surgical Quality Improvement Programs
8. Patient Reported Outcomes
9. Safety in the Surgical Environment
10. Advances and Training Considerations in Robotic Surgery
11. Advances and Training Considerations in Laparoscopic Surgery
12. Advances and Training Considerations in Endoscopy and Endoscopic Surgery
13. Telehealth in Surgery
14. Health Inequities and Disparities in Surgery
15. Global Surgery
16. Ethics and Professionalism in Surgery
17. Surgeon Health-Ergonomics
18. Surgeon Health and Well Being
Section 2 Perioperative Management
19. Principles of Preoperative and Operative Surgery
20. Anesthesiology Principles, Pain Management and Sedation
21. Optimizing surgical outcomes: Prehabilitation and rehabilitation
22. Enhanced Recovery After Surgery (ERAS): Evidence Based Perioperative Pathways to Optimize Outcomes
23. Wound Healing
24. The Evolving Role of the Microbiome in Surgical Practice
25. Surgical Site Infections
26. Surgical Complications: Overview and Grading
27. Surgery in the Geriatric Patient
28. Surgical in The Pregnant Patient
29. Surgical Considerations in the Transgender Patient
30. Surgical Palliative Care
31. Emerging Technologies in Surgery: Informatics, Electronics, and Smart Spaces
Section 3 Trauma and Critical Care
32. The Inflammatory Response
33. Shock, Electrolytes, and Fluid
34. Metabolism and Nutrition in Surgical Patients
35. Primary Soft Tissue Infections
36. Management of Acute Trauma
37. The Difficult Abdominal Wall
38. Management of Vascular Trauma
39. Management of Urologic Trauma
40. Emergency Care of Musculoskeletal Injuries
41. Emergency Care of Neurologic Injuries
42. Management of Pediatric Trauma
43. Burns
44. The Outdoors – Venomous Bites and Stings and Environmental Exposure
45. Management of Chronic Wounds
46. Surgical Critical Care
47. Moving Operating Room Procedures to the Intensive Care Unit
48. The Surgeon's Role in Disaster Management
Section 4: Transplantation and Immunology
49. Transplantation Immunobiology and Immunosuppression
50. Regenerative Medicine and Its Applications to Surgery
51. Surgical Considerations in Transplant Patients Undergoing Non-Transplant Related Procedures and Operating in Patients with Portal Hypertension
52. Kidney Transplantation
53. Liver Transplantation
54. Pancreas Transplantation
55. Islet Transplantation for the General Surgeon
56. Small Bowel Transplantation
57. Heart Transplantation
58. Lung Transplantation
59. Soft Tissue Transplantation
Section 5 Surgical Oncology
60. Tumor Biology and Tumor Markers
61. Tumor Immunology and Immunotherapy
62. Surgical Considerations in Cancer Patients Undergoing Non-Cancer Related Procedures
63. Melanoma and Cutaneous Malignancies
64. Sarcomas of the Soft Tissues, Retroperitoneum and Bone
65. Gastrointestinal Stromal Tumor
66. Benign Diseases of the Head and Neck
67. Head and Neck Cancers
68. Diseases of the Breast
69. Plastic Surgical Considerations in Cancer Surgery
70. Peritoneal Malignancies and HIPEC
71. Surgeon's Approach to Lymphadenopathy
72. The Spleen
Section 6 Endocrine Disorders
73. The Thyroid
74. Parathyroid
75. The Adrenal Glands
76. Pancreatic Neuroendocrine Tumors
77. Neuroendocrine Neoplasms (Carcinoid Tumors)
78. The Multiple Endocrine Neoplasia Syndromes
Section 7 Abdominal Wall Hernias
79. Preoperative Management of the Hernia Patient
80. Ventral Hernias
81. Hernias of the Abdominal Wall: Atypical Locations
82. Inguinal Hernias
Section 8 Alimentary
83. Benign Esophageal Disorders
84. Esophageal Cancer
85. The Acute Abdomen
86. Stomach
87. Gastric Cancer
88. Biliary System
89. The Liver
90. Secondary Tumors of the Liver
91. Small Intestine
92. Exocrine Pancreas
93. Pancreatic Cancer
94. The Appendix
95. Colon and Rectum
96. Cancers of the Colon, Rectum and Anus
97. Benign Anorectal Disorders
98. Acute Gastrointestinal Hemorrhage
99. Morbid Obesity
Section 9 Vascular
100. Hemostasis and Thrombosis
101. Contemporary Management of Carotid Disease
102. Aortic Disease
103. Peripheral Occlusive Disease
104. Extremity Amputations in the Modern Era: Indications, Technique and Outcomes
105. Peripheral Aneurysmal Disease
106. Visceral Ischemic Syndromes: Acute/Chronic Mesenteric Ischemia
107. Dialysis Access
108. Venous Disease
109. The Lymphatics
Section 10 Cardiothoracic Surgery
110. Lung, Chest Pleura and Mediastinum
111. Acquired Heart Disease: Coronary
112. Acquired Heart Disease: Valvular
113. Congenital Heart Disease
114. Pulmonary Embolism-Acute and Chronic
115. Percutaneous Heart Procedures
116. ECMO
Section 11 Specialties in General Surgery Subspecialty Considerations Relevant for the General Surgeon
117. Pediatric Surgery
118. Maternal-Fetal Surgery
119. Hand Surgery
120. Gynecologic Surgery
121. Urologic Surgery
1. Surgical Education Past, Present and Future
2. Surgical Simulation and new ways to optimize performance
3. Certification of Surgeon Competence
4. Preoperative Risk Assessment and Alterations in the COVID Era
5. Social Determinants of Health and Their Impact on Surgical Outcomes
6. Critical Assessment of Surgical Outcomes and Health Service Research
7. Surgical Quality Improvement Programs
8. Patient Reported Outcomes
9. Safety in the Surgical Environment
10. Advances and Training Considerations in Robotic Surgery
11. Advances and Training Considerations in Laparoscopic Surgery
12. Advances and Training Considerations in Endoscopy and Endoscopic Surgery
13. Telehealth in Surgery
14. Health Inequities and Disparities in Surgery
15. Global Surgery
16. Ethics and Professionalism in Surgery
17. Surgeon Health-Ergonomics
18. Surgeon Health and Well Being
Section 2 Perioperative Management
19. Principles of Preoperative and Operative Surgery
20. Anesthesiology Principles, Pain Management and Sedation
21. Optimizing surgical outcomes: Prehabilitation and rehabilitation
22. Enhanced Recovery After Surgery (ERAS): Evidence Based Perioperative Pathways to Optimize Outcomes
23. Wound Healing
24. The Evolving Role of the Microbiome in Surgical Practice
25. Surgical Site Infections
26. Surgical Complications: Overview and Grading
27. Surgery in the Geriatric Patient
28. Surgical in The Pregnant Patient
29. Surgical Considerations in the Transgender Patient
30. Surgical Palliative Care
31. Emerging Technologies in Surgery: Informatics, Electronics, and Smart Spaces
Section 3 Trauma and Critical Care
32. The Inflammatory Response
33. Shock, Electrolytes, and Fluid
34. Metabolism and Nutrition in Surgical Patients
35. Primary Soft Tissue Infections
36. Management of Acute Trauma
37. The Difficult Abdominal Wall
38. Management of Vascular Trauma
39. Management of Urologic Trauma
40. Emergency Care of Musculoskeletal Injuries
41. Emergency Care of Neurologic Injuries
42. Management of Pediatric Trauma
43. Burns
44. The Outdoors – Venomous Bites and Stings and Environmental Exposure
45. Management of Chronic Wounds
46. Surgical Critical Care
47. Moving Operating Room Procedures to the Intensive Care Unit
48. The Surgeon's Role in Disaster Management
Section 4: Transplantation and Immunology
49. Transplantation Immunobiology and Immunosuppression
50. Regenerative Medicine and Its Applications to Surgery
51. Surgical Considerations in Transplant Patients Undergoing Non-Transplant Related Procedures and Operating in Patients with Portal Hypertension
52. Kidney Transplantation
53. Liver Transplantation
54. Pancreas Transplantation
55. Islet Transplantation for the General Surgeon
56. Small Bowel Transplantation
57. Heart Transplantation
58. Lung Transplantation
59. Soft Tissue Transplantation
Section 5 Surgical Oncology
60. Tumor Biology and Tumor Markers
61. Tumor Immunology and Immunotherapy
62. Surgical Considerations in Cancer Patients Undergoing Non-Cancer Related Procedures
63. Melanoma and Cutaneous Malignancies
64. Sarcomas of the Soft Tissues, Retroperitoneum and Bone
65. Gastrointestinal Stromal Tumor
66. Benign Diseases of the Head and Neck
67. Head and Neck Cancers
68. Diseases of the Breast
69. Plastic Surgical Considerations in Cancer Surgery
70. Peritoneal Malignancies and HIPEC
71. Surgeon's Approach to Lymphadenopathy
72. The Spleen
Section 6 Endocrine Disorders
73. The Thyroid
74. Parathyroid
75. The Adrenal Glands
76. Pancreatic Neuroendocrine Tumors
77. Neuroendocrine Neoplasms (Carcinoid Tumors)
78. The Multiple Endocrine Neoplasia Syndromes
Section 7 Abdominal Wall Hernias
79. Preoperative Management of the Hernia Patient
80. Ventral Hernias
81. Hernias of the Abdominal Wall: Atypical Locations
82. Inguinal Hernias
Section 8 Alimentary
83. Benign Esophageal Disorders
84. Esophageal Cancer
85. The Acute Abdomen
86. Stomach
87. Gastric Cancer
88. Biliary System
89. The Liver
90. Secondary Tumors of the Liver
91. Small Intestine
92. Exocrine Pancreas
93. Pancreatic Cancer
94. The Appendix
95. Colon and Rectum
96. Cancers of the Colon, Rectum and Anus
97. Benign Anorectal Disorders
98. Acute Gastrointestinal Hemorrhage
99. Morbid Obesity
Section 9 Vascular
100. Hemostasis and Thrombosis
101. Contemporary Management of Carotid Disease
102. Aortic Disease
103. Peripheral Occlusive Disease
104. Extremity Amputations in the Modern Era: Indications, Technique and Outcomes
105. Peripheral Aneurysmal Disease
106. Visceral Ischemic Syndromes: Acute/Chronic Mesenteric Ischemia
107. Dialysis Access
108. Venous Disease
109. The Lymphatics
Section 10 Cardiothoracic Surgery
110. Lung, Chest Pleura and Mediastinum
111. Acquired Heart Disease: Coronary
112. Acquired Heart Disease: Valvular
113. Congenital Heart Disease
114. Pulmonary Embolism-Acute and Chronic
115. Percutaneous Heart Procedures
116. ECMO
Section 11 Specialties in General Surgery Subspecialty Considerations Relevant for the General Surgeon
117. Pediatric Surgery
118. Maternal-Fetal Surgery
119. Hand Surgery
120. Gynecologic Surgery
121. Urologic Surgery
- Edition: 22
- Published: June 1, 2025
- Imprint: Elsevier
- Language: English
- Hardback ISBN: 9780443379161
- Hardback ISBN: 9780443124341
- eBook ISBN: 9780443124358
DS
Douglas Scott Tyler
Douglas Tyler, MD, MSHCT, currently holds the John Woods Harris Distinguished Chair in Surgery at the University of Texas Medical Branch (UTMB) in Galveston, where he is also a Professor and Chairman of the Department of Surgery. He also holds an Adjunct Professor appointment at the University of Texas MD Anderson Cancer Center in the Department of Surgical Oncology. Dr. Tyler’s previous leadership positions included Division Chief of Surgical Oncology and Vice Chairman of the Department of Surgery at Duke University Medical Center; Chief of the Surgical Services at the Durham VA Medical Center; and within the Duke Cancer Institute he was both Head of the Melanoma program and Associate Director of the Duke Cancer Institute in charge of Strategic Planning. Dr. Tyler’s clinical practice focuses on GI cancers and melanoma. He has published over 270 peer-reviewed manuscripts and 75 book chapters. Dr. Tyler was inducted into the American College of Surgeons Academy of Master Surgeon Educators in 2019. Dr. Tyler is a Senior Director on the American Board of Surgery, having completed a six-year term as a Director in 2016. Dr. Tyler is the immediate past President of the Society of Surgical Oncology and Councilperson at large for the Society of Surgical Chairs.
Affiliations and expertise
John Woods Harris Distinguished Chair in Surgery, Professor and Chairman, Department of Surgery, University of Texas Medical Branch, John Sealy School of Medicine, USA