
Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease
Volume 2
- 6th Edition - June 23, 2020
- Editors: Roger N. Rosenberg, Juan M. Pascual
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 1 3 8 6 6 - 3
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 1 3 8 6 7 - 0
Rosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Sixth Edition: Volume Two provides a comprehensive introduction and reference to the foundatio… Read more

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Request a sales quoteRosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Sixth Edition: Volume Two provides a comprehensive introduction and reference to the foundations and practical aspects relevant to the majority of neurologic and psychiatric disease. This updated volume focuses on degenerative disorders, movement disorders, neuro-oncology, neurocutaneous disorders, epilepsy, white matter diseases, neuropathies and neuronopathies, muscle and neuromuscular junction disorders, stroke, psychiatric disease, and a neurologic gene map. A favorite of over three generations of students, clinicians and scholars, this new edition retains and expands on the informative, concise and critical tone of the first edition.
This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, related professionals, and for the neuroscience and neurology research community at large. The content covers all aspects essential to the practice of neurogenetics to inform clinical diagnosis, treatment and genetic counseling.
- Provides comprehensive coverage on the neurogenetic foundation of neurological and psychiatric disease
- Presents detailed coverage of genomics, animal models and diagnostic methods, with new coverage on evaluating patients with biochemical abnormalities or gene mutations
- Includes new chapters on the pharmacogenomics of epilepsy and the most recent updates in molecular genetics, focusing on neurodegenerative and psychiatric diseases
Clinical neurologists, psychiatrists, psychologists, neuroscience researchers, clinical neurology researchers, general medical practitioners, and genetic and molecular biologists with an interest in neurogenetics
1. Genomics of Alzheimer’s disease
2. Parkinson disease and related disorders
3. Frontotemporal dementia
4. The neuronal ceroid-lipofuscinoses (Batten disease)
SECTION II. MOVEMENT DISORDERS
5. The inherited ataxias
6. Friedreich ataxia
7. Ataxia-telangiectasia
8. Dystonia
9. Huntington’s disease: clinical features, disease mechanisms, and management
10. The hereditary spastic paraplegias
SECTION III. NEURO-ONCOLOGY
11. Glioblastoma
SECTION IV. NEUROCUTANEOUS DISORDERS
12. Neurofibromatosis type 1
13. Tuberous sclerosis complex
14. Sturge-Weber syndrome
15. Hemangioblastomas of the central nervous system
16. Incontinentia pigmenti
SECTION V. EPILEPSY
17. Epilepsy genetics—considerations for clinical practice today and for the future
SECTION VI. WHITE MATTER DISEASES
18. Multiple sclerosis
19. Vanishing white matter disease
SECTION VII. NEUROPATHIES AND NEURONOPATHIES
20. Amyotrophic lateral sclerosis
21. Peripheral neuropathies
22. Spinal muscular atrophy
23. Pain genetics
SECTION VIII. MUSCLE AND NEUROMUSCULAR JUNCTION DISORDERS
24. Dystrophinopathies
25. Limb-girdle muscular dystrophy
26. The congenital myopathies
27. The distal myopathies
28. Hereditary inclusion-body myopathies
29. The myotonic dystrophies
30. Facioscapulohumeral muscular dystrophy
31. Muscle channelopathies: periodic paralyses and nondystrophic myotonias
32. Congenital myasthenic syndromes
SECTION IX. STROKE
33. Cerebral vasculopathies
34. Coagulopathies
35. Sickle cell disease
Sub-Section: Psychiatric Disease
36. Unipolar depression
37. Bipolar disorder
38. Schizophrenia
39. Obsessive
40. Tourette syndrome
41. Addiction
SECTION X. A NEUROLOGIC GENE MAP
42. A neurologic gene map
- No. of pages: 828
- Language: English
- Edition: 6
- Published: June 23, 2020
- Imprint: Academic Press
- Hardback ISBN: 9780128138663
- eBook ISBN: 9780128138670
RR
Roger N. Rosenberg
JP
Juan M. Pascual
Juan M. Pascual, M.D., Ph.D., is the inaugural holder of The Once Upon a Time Foundation Professorship in Pediatric Neurologic Diseases and also holds the Ed and Sue Rose Distinguished Professorship in Neurology. His laboratory research interests span virtually the entire field of neuroscience, including medical neuroscience, from molecular structure and function (including drug action), neural physiology and metabolism at the cellular, circuit and whole-brain level and neurogenetics, all of which is complemented with neurological patient care and clinical trials. Laboratory research greatly influences his clinical activities and patient observations guide his laboratory research direction. As a clinician, Dr. Pascual specializes in genetic and metabolic diseases of the nervous and neuromuscular systems of infants, children, and adults with a particular emphasis on complex diagnostic problems, second opinions for patients visiting from the rest of the U.S. and abroad, and in clinical trials. Dr. Pascual has special clinical research expertise in undiagnosed and rare diseases, glucose metabolism, mitochondrial, degenerative, and multi-organ disorders. Dr. Pascual is a tenured faculty member in four Departments at UT Southwestern Medical Center: Neurology and Neurotherapeutics, Physiology, Pediatrics, and the Eugene McDermott Center for Human Growth & Development / Center for Human Genetics. He is also Director of the Rare Brain Disorders Program (Clinic and Laboratory). He is also a member of the Division of Pediatric Neurology, of the graduate Ph.D. programs in Neuroscience and Integrative Biology, and of the postgraduate clinical training programs in Neurology, Pediatric Neurology, Pediatrics, and Medical Genetics. He teaches at UT Southwestern Medical School. In addition, Dr. Pascual is an adjunct professor in the Department of Biological Sciences at the School of Natural Sciences and Mathematics, The University of Texas at Dallas. Dr. Pascual directs a highly collaborative research laboratory and is credentialed campus-wide at Children's Medical Center Dallas, UT Southwestern University Hospitals and Clinics, and Parkland Memorial Hospital, where he consults on inpatients and outpatients with particularly complex or severe diseases. Much of his research is funded by the National Institutes of Health. Dr. Pascual received his M.D. degree with unique distinction from the Universidad de Granada, Spain, one of the oldest universities in the world, founded in 1349 by Yusuf I, Sultan of Granada and one of the builders of the Alhambra. He received his Ph.D. degree in Molecular Physiology and Biophysics from Baylor College of Medicine in Houston, Texas, under Arthur M. Brown, M.D., Ph.D., McCollum Professor and Chair. His postdoctoral research was conducted under Arthur Karlin, Ph.D., Higgins Professor and Director of the Center for Molecular Recognition, College of Physicians and Surgeons of Columbia University and, later, at the Colleen Giblin Research Laboratories for Pediatric Neurology at the same institution under a Neurological Sciences Academic Development Award from the National Institute of Neurological Disorders and Stroke. He also received residency training in Pediatrics at Washington University School of Medicine - St. Louis Children's Hospital and in Neurology and Pediatric Neurology at the Neurological Institute of New York - Columbia University Medical Center. He received certification in Neurology with Special Qualification in Child Neurology from the American Board of Psychiatry and Neurology.