Regulatory T-Cells

Contributors

Chapter 1: Stability of Regulatory T-cell Lineage

1. Introduction

2. The Treg Cell Lineage

3. Differentiation and Functional Adaptation of Foxp3+ Treg Cells

4. Regulation of Treg Cell Differentiation by Foxp3

5. Controversies Over Stability Versus Plasticity of the Treg Cell Lineage

6. Concluding Remarks

Chapter 2: Thymic and Peripheral Differentiation of Regulatory T Cells

1. Introduction

2. Thymic Development of Treg Cells

3. Peripheral Treg Cell Development

4. Summary

Chapter 3: Regulatory T Cells in Infection

1. Introduction

2. Regulatory T Cells

3. Infections

4. Treg Activation—a Common Immune-Evasion Strategy Achieved Through Diverse Routes

5. Antigen Specificity of Natural and Adaptive Tregs in Infection

6. Tregs and the Hygiene Hypothesis

7. Conclusion

Chapter 4: Biological Functions of Regulatory T Cells

1. Introduction

2. Biologic Functions of Polyclonal Tregs In Vivo

3. Biologic Effects of Antigen-Specific Tregs In Vivo

4. Conclusions and Speculations

Chapter 5: Extrathymic Generation of Regulatory T Cells—Chances and Challenges for Prevention of Autoimmune Disease

1. Introduction

2. Intra- and Extrathymic Induction of Foxp3+ Tregs

3. Enhancement of e.t. Treg Generation

4. Tolerogenic Vaccination by Strong-Agonist Mimetopes of Self-Antigens in Order to Prevent Autoimmune Disease

5. Concluding Remarks

Index

Contents of recent volumes