
Receptor Endocytosis and Signalling in Health and Disease - Part B
- 1st Edition, Volume 196 - February 22, 2023
- Editors: Indra Mani, Vijai Singh
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 9 5 5 5 9 - 1
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 5 5 6 0 - 7
Receptor Endocytosis and Signalling in Health and Disease, Part B, Volume 196 highlights the different aspects of receptor endocytosis and signaling, covering several receptors… Read more

Receptor Endocytosis and Signalling in Health and Disease, Part B, Volume 196 highlights the different aspects of receptor endocytosis and signaling, covering several receptors which are associated with different organs and that play a key role in normal functioning in the body, including somatostatin, Mas receptor, AMPA, Dopamine, 5-HT1-2, GABA, GPCR, nuclear receptor, Integrin, BCR, CRHR1, etc. Chapters in this new release include Internalization of somatostatin receptors in brain and periphery, Mas receptor, signaling and trafficking in health and disease, Endocytosis of AMPA receptors: Role in neurological conditions, Endocytosis of dopamine receptor: Signaling in brain, and more.
Additional chapters cover Endocytosis of LXRs: Signalling in liver, Endocytosis of LDL receptor: Importance in cardiovascular diseases, Advances in the molecular level understanding of G-protein-coupled receptor, Nuclear receptor: Structure and function, Integrin receptor trafficking in health and disease, B Cell Receptor (BCR) endocytosis,CRHR1 endocytosis: Spatiotemporal regulation of receptor signaling, and much more.
- Provides information on the structure and function of nuclear receptors
- Discusses the basic pathways involved in receptor internalization, subcellular trafficking, metabolic degradation, and signaling
- Includes a wide range of neurological receptors and their roles
Preface
Indra Mani and Vijai Singh
Adhiraj Roy
2. Prion receptors, prion internalization, intra- and inter-cellular transport
Luigi Celauro, Marco Zattoni and Giuseppe Legname
3. Internalization of somatostatin receptors in brain and periphery
Zsolt Csaba and Pascal Dournaud
4. Endocytosis of AMPA receptors: Role in neurological conditions
Norbert Bencsik, Carlos Omar Oueslati Morales, Angelika Hausser and Katalin Schlett
5. Endocytosis of dopamine receptor: Signaling in brain
Ichiro Kawahata and Kohji Fukunaga
6. Endocytosis and signaling of 5-HT1A receptor
Ragini, Sakshi, Ashok Saini and Indra Mani
7. Endocytosis of GABA receptor: Signaling in nervous system
Preeti Sharma, B. Sharan Sharma, Hardik Raval and Vijai Singh
8. The endocytosis, trafficking, sorting and signaling of neurotrophic receptors
Katja Burk
9. Endocytosis of glutamate receptor: Signaling in neurological conditions
Prerna Yadav, Mansi Podia, Shashi Prabha Kumari and Indra Mani
10. Nuclear receptor: Structure and function
Pranati Sar
11. CRHR1 endocytosis: Spatiotemporal regulation of receptor signaling
Paula A. dos Santos Claro, Micaela Silbermins, Carolina Inda and Susana Silberstein
12. Amyloid precursor protein in Alzheimer's disease
Rupesh Maurya, Gargi Bhattacharjee, Khushal Khambhati, Nisarg Gohil, Priyanka Singh, Indra Mani, Dinh-Toi Chu, Suresh Ramakrishna, Pau Loke Show and Vijai Singh
13. Integrin receptor trafficking in health and disease
Victor Samuel, Thejaswitha Rajeev, Lariza Ramesh and Ananthalakshmy Sundararaman
14. Synthetic receptors in medicine
Sarita Mishra, Mahima Raval, Vijai Singh and Anand K. Tiwari
15. Receptor biology: Challenges and opportunities
Indra Mani and Vijai Singh
- Edition: 1
- Volume: 196
- Published: February 22, 2023
- Language: English
IM
Indra Mani
VS
Vijai Singh
Prof. Vijai Singh is currently serving as Head of the Department of Biosciences, School of Science and Dean (Research & Innovation) at Indrashil University, Rajpur, Mehsana, India. Prior to this, he held the position of Associate Professor in the same department at Indrashil University. He has also served as Assistant Professor in the Department of Biological Sciences and Biotechnology at the Institute of Advanced Research, Gandhinagar, and in the Department of Biotechnology at the Invertis University, Bareilly, India. Earlier of his career, Prof. Singh worked as a Postdoctoral Fellow in the Synthetic Biology Group at the Institute of Systems and Synthetic Biology, Paris, France and at the School of Energy & Chemical Engineering at the Ulsan National Institute of Science and Technology, Ulsan, South Korea. He earned his Ph.D. in Biotechnology in 2009 from the ICAR-National Bureau of Fish Genetic Resources, Uttar Pradesh Technical University, Lucknow, India. His doctoral research focused on the development of molecular and immunoassays for the diagnosis of Aeromonas hydrophila. Prof. Singh’s research interests lies in the design and construction of novel biosynthetic pathways for production of medically and industrially important biomolecules. His laboratory is also actively engaged in developing CRISPR-Cas systems for gene knock out, knock in, gene regulation and diagnostic. With over 15 years of research and teaching experience, his areas of expertise include synthetic biology, metabolic engineering, bioinformatics, microbiology, and industrial microbiology. He has an extensive academic record, with over 110 articles, 89 book chapters, 26 books and 3 patents to his credits. Prof. Singh has received number of prestigious awards, including the Bioclues Innovation, Research and Development Award (2023) from the BIOCLUES Society, the Vice Chancellor's Best Research Award (2023) from Indrashil University, and the Agathiyar Chemical Biology Award (2023) from the Society of Chemical and Synthetic Biology. At Indrashil University, he currently serves as chairman of the Board of Study, and is a member of the Academic Council of Indrashil University. He also holds the position of the Member Secretary of the Institutional Biosafety Committee (IBSC) at the university. Dr. Singh is actively involved in national and international scientific advisory roles.