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Proteolytic Signaling in Health and Disease

1st Edition - October 13, 2021

Editor: Andre Zelanis

Language: English
Paperback ISBN:
9 7 8 - 0 - 3 2 3 - 8 5 6 9 6 - 6
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 8 5 6 9 7 - 3

In recent years, powered by evolving technologies and experimental design, studies have better illuminated the regulating role of proteolytic enzymes across human development and… Read more

Proteolytic Signaling in Health and Disease

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In recent years, powered by evolving technologies and experimental design, studies have better illuminated the regulating role of proteolytic enzymes across human development and pathologies. Proteolytic Signaling in Health and Disease provides an in-depth discussion of fundamental physiological and developmental processes regulated by proteases, from protein turnover and autophagy to antigen processing and presentation and major histocompatibility complex (MHC) molecules. Moving on from basic biology, international chapter authors examine a range of pathological conditions associated with proteolysis, including inflammation, wound healing, and cancer. Later chapters discuss the newly discovered network of connected events among proteases (and their inhibitors), the so-called ‘protease web’, and how best to study it. This book also empowers new research with up-to-date analytical methods and step-by-step protocols for studying proteolytic signaling events.