Protein Digestion-Derived Peptides

Chemistry, Bioactivity, and Health Effects

1st Edition - April 12, 2024
Editors: Cristina Martinez-Villaluenga, Blanca Hernandez-Ledesma
Language: English
Paperback ISBN:
9 7 8 - 0 - 4 4 3 - 1 9 1 4 1 - 1
eBook ISBN:
9 7 8 - 0 - 4 4 3 - 1 5 4 6 7 - 6

Protein Digestion-Derived Peptides: Chemistry, Bioactivity, and Health Effects presents the latest international advances in fundamental and applied research on the impact of… Read more

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Protein Digestion-Derived Peptides: Chemistry, Bioactivity, and Health Effects presents the latest international advances in fundamental and applied research on the impact of gastrointestinal digestion on the release of bioactive peptides from food sources.

This book covers the fundamentals and applications of gastrointestinal digestion and absorption models as well as the impact of food matrices, their components and protein characteristics, and peptide bioactivity, bioaccessibility, and bioavailability. Moreover, the book expands coverage in vitro and in vivo approaches to simulate gastrointestinal digestion of food proteins and absorption models to evaluate the bioaccessibility and bioavailability of released peptides.

Developed for nutrition researchers, food scientists, and pharmaceutical scientists, this book is a welcomed resource for those who wish to understand the impact of peptides on chronic disease.

Cover image
Title page
Table of Contents
Copyright
List of contributors
Preface
Chapter 1. Food protein digestion by in vitro static approaches
Abstract
1.1 Introduction
1.2 Food protein digestion
1.3 Static models for food protein digestion investigations
1.4 Main applications of INFOGEST protocols to protein digestion
1.5 Other static models including the addition of a colon step: main potentialities
1.6 Conclusions and future perspectives
References
Chapter 2. Modeling elderly gastrointestinal digestion for the evaluation of the release of bioactive peptides
Abstract
2.1 Introduction
2.2 Age-related changes in the gastrointestinal tract
2.3 In vitro simulation of elderly gastrointestinal digestion
2.4 Bioactive peptides and aging
2.5 In vitro studies of bioactive peptides bioaccessibility using elderly gastrointestinal conditions
2.6 Conclusion
References
Chapter 3. Oral bioaccessibility and bioavailability of protein hydrolysates and bioactive peptides derived from food sources
Abstract
3.1 Background
3.2 Susceptibility of peptides against endoproteinase and exopeptidase
3.3 Food-derived peptides in body
3.4 Biological functions of food-derived peptides in the human body
3.5 Conclusion and future prospect
References
Chapter 4. Dynamic simulation of food protein digestion and bioactive peptide release
Abstract
4.1 Introduction
4.2 Physiology of human digestion
4.3 Gastrointestinal digestion models
4.4 Simulation of digestion of food proteins using dynamic models
4.5 Conclusions and future perspectives
References
Chapter 5. Assessing the bioactivity of dietary peptides and their resistance to digestion: a combined approach using in silico, in vitro, and in vivo analyses
Abstract
5.1 Introduction
5.2 Conclusions
References
Chapter 6. Bioactive peptides from milk and dairy proteins: models of digestion and intestinal barrier
Abstract
6.1 Introduction
6.2 From proteins to peptides: methods to obtain bioactive peptides and amino acids
6.3 In vitro, ex vivo, and multiorgans intestinal tissue-based models
6.4 Conclusion
References
Chapter 7. Bioactive peptides from marine sources after simulated gastrointestinal digestion
Abstract
7.1 Introduction
7.2 In vitro gastrointestinal digestion
7.3 In silico gastrointestinal digestion
7.4 Prospects and challenges
References
Chapter 8. Bioactive peptides released from meat and meat products during gastrointestinal digestion
Abstract
8.1 Introduction
8.2 Bioactive peptides released from meat
8.3 Bioactive peptides released from meat-derived products
8.4 In vivo studies
8.5 In silico studies
8.6 Conclusions and future perspectives
References
Chapter 9. Bioactive peptides released from pseudo-cereal proteins during gastrointestinal digestion
Abstract
9.1 Pseudo-cereals: general aspects, proteins, and their susceptibility to proteolysis by enzymes of the gastrointestinal tract
9.2 Bioactivities of peptides from simulated gastrointestinal digestion of purified proteins and protein isolates/concentrates
9.3 Bioactivities of peptides from simulated gastrointestinal digestion of flour and food matrices
9.4 Conclusion
References
Chapter 10. Bioactive peptides released from legumes during gastrointestinal digestion
Abstract
10.1 Introduction
10.2 Legume proteins
10.3 Legume protein digestion
10.4 The effect of food processing on legumes protein digestibility
10.5 Bioactivity of legume peptides/protein hydrolysates over digestion
10.6 The role of bioinformatic analysis in legume-based bioactive peptide release from gastrointestinal digestion
10.7 Conclusion
10.8 Challenges and future perspectives
References
Chapter 11. Bioactive peptides released from Cucurbitaceae seed proteins during gastrointestinal digestion
Abstract
Abbreviations
11.1 Introduction
11.2 Cucurbitaceae seed proteins as a source of bioactive peptides
11.3 Bioaccessibility of Cucurbitaceae seed hydrolysates and derived bioactive peptides
11.4 Conclusions and future perspectives
Funding
Acknowledgments
Conflicts of interest
References
Chapter 12. Bioactive peptides released from microalgae during gastrointestinal digestion
Abstract
12.1 Introduction
12.2 Microalgae-based proteins and peptides
12.3 Release of bioactive peptides from microalgae
12.4 Conclusions
References
Chapter 13. Bioactive peptides released from seaweeds during gastrointestinal digestion
Abstract
List of Abbreviations
13.1 Introduction
13.2 Protein content and composition of seaweeds
13.3 Seaweed protein hydrolysis
13.4 Seaweed protein digestibility
13.5 Bioactive properties of seaweed-derived peptides
13.6 Conclusion
Acknowledgments
References
Chapter 14. Bioactive peptides released from edible insects during gastrointestinal digestion
Abstract
14.1 Introduction
14.2 Edible insects
14.3 Conclusions
References
Chapter 15. Bioactive peptides from fruit food waste after simulated gastrointestinal digestion
Abstract
List of abbreviations
15.1 Introduction
15.2 Protein content in fruit waste
15.3 Fruit waste bioactive peptides released in gastrointestinal digestion
15.4 Bioactivity of peptides
15.5 Concluding remarks
Acknowledgments
Conflict of interest
References
Index

Life sciences

Physical sciences & Engineering

Social sciences & Humanities

Health