Principles of Developmental Genetics
- 1st Edition - July 19, 2007
- Editor: Sally A. Moody
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 3 6 9 5 4 8 - 2
- eBook ISBN:9 7 8 - 0 - 0 8 - 0 5 5 0 7 1 - 8
Unlike anything currently available in the market, Dr. Sally A. Moody and a team of world-renowned experts provide a groundbreaking view of developmental genetics that will… Read more
Unlike anything currently available in the market, Dr. Sally A. Moody and a team of world-renowned experts provide a groundbreaking view of developmental genetics that will influence scientific approaches in embryology, comparative biology, as well as the newly emerging fields of stem cell biology and regenerative medicine. Principles of Developmental Genetics highlights the intersection of developmental biology with new revolutionary genomic technologies, and details how these advances have accelerated our understanding of the molecular genetic processes that regulates development. This definitive resource provides researchers with the opportunity to gain important insights into the clinical applicability of emerging new technologies and animal model data. This book is a must-have for all researchers in genetics, developmental biology, regenerative medicine, and stem cell biology.
• Includes new research not previously published in any other book on the molecular genetic
processes that regulates development
• Chapters present a broad understanding on the application of animal model systems, allowing
researchers to better treat clinical disorders and comprehend human development
• Relates the application of new technologies to the manipulation of stem cells, causes of
human birth defects, and several human disease conditions
• Each chapter includes a bulleted summary highlighting clinical aspects of animal models
processes that regulates development
• Chapters present a broad understanding on the application of animal model systems, allowing
researchers to better treat clinical disorders and comprehend human development
• Relates the application of new technologies to the manipulation of stem cells, causes of
human birth defects, and several human disease conditions
• Each chapter includes a bulleted summary highlighting clinical aspects of animal models
Clinical researchers and graduate students in genetics, developmental biology, cell and molecular biology, stem cell research, and evolutionary biology
I. The Impact of Genetic and Genomic Tools on Developmental Biology
1. Untangling the Gordian knot: Cell Signaling Events that Instruct Development
Philippe Soriano and Renée V. Hoch
2. Finding Gene Expression Changes using Microarray Technology
Tadayoshi Hayata and Ken W.Y. Cho
3. Chemical and Functional Genomic Approaches to Study Stem Cell Biology and Regeneration
Wen Xiong and Sheng Ding
4. Assessing Neural Stem Cell Properties using Large Scale Genomic Analysis
Soojung Shin, Jonathan D. Chesnut and Mahendra S. Rao
5. Epigenetic Influences on Gene Expression Pathways
Sundeep Kalantry and Terry Magnuson
6. New Insights into Vertebrate Origins
Billie J. Swalla
7. Understanding Human Birth Defects Through Model Organism Studies
Feyza Engin and Brendan Lee
II. Early Embryology, Fate Determination and Patterning
8. Germ Line Determinants and Oogenesis
Kelly M Haston and Renee A Reijo Pera
9. Patterning the Anterior-Posterior Axis during Drosophila Embryogenesis
Kristy L. Kenyon
10. Anterior-Posterior Patterning in Mammals
Sigolène M. Meilhac
11. Signaling Cascades, Gradients, and Gene Networks in Dorsal/Ventral Patterning
Girish S. Ratnaparkhi and Albert J. Courey
12. Early Development of Epidermis and Neural Tissue
Keiji Itoh and Sergei Y. Sokol
13. Formation of the Embryonic Mesoderm
Lisa L. Chang and Daniel S. Kessler
14. Endoderm
Debora Sinner, James M Wells and Aaron M. Zorn
15. Notch Signaling – A Versatile Tool for the Fine Patterning of Cell Fate in Development
Ajay B. Chitnis
16. Multiple roles of T-box genes
L. A. Naiche and Virginia E. Papaioannou
III. Morphogenetic and Cell Movements
17. Gastrulation in Vertebrates
Lilianna Solnica-Krezel and Diane S. Sepich
18. Regulation of tissue separation in the amphibian embryo
Herbert Steinbeisser
19. Role of the Basement Membrane in Cell Migration
Kiyoji Nishiwaki, Kiyoji Nishiwaki and Yukihiko Kubota
20. Epithelial Morphogenesis
Ronit Wilk and Howard D. Lipshitz
21. Branching Morphogenesis of Mammalian epithelia
Jamie Davies
22. The Roles of Ephrin-Eph in Morphogenesis
Ira O. Daar
IV. Ectodermal Organs
23. Neural Cell Fate Determination
Stephen N. Sansom and Frederick J. Livesey
24. Pathfinding and Patterning of Axonal Connections
S.A Linn, S.R. Kadison and C.E. Krull
25 Retinal Development
Kathryn B. Moore and Monica L. Vetter
26. Neural Crest Determination
Roberto Mayor
27. Determination of Pre-Placodal Ectoderm and Sensory Placodes
Sally A. Moody
28. Molecular Genetics of Tooth Development
Irma Thesleff
29. The Inner Ear
Donna F. Fekete and Ulrike J. Sienknecht
30. Craniofacial Formation and Congenital Defects
S.A. Brugmann and J.A. Helms
V. Mesodermal Organs
31. Induction of the Cardiac Lineage
Andrew S. Warkman and Paul A. Krieg
32. Heart Patterning and Congenital Defects
John Belmont
33. Blood Vessel Formation
Karina Yaniv and Brant M. Weinstein
34. Blood Induction and Embryonic Formation
Xiaoying Bai and Leonard I. Zon
35. Topics in Vertebrate Kidney Formation: A Comparative Perspective
Thomas M. Schultheiss
36. Development of The Genital System
Hongling Du hugh S Taylor
37. Diaphragmatic Embryogenesis and Human Congenital Diaphragmatic Defects
Kate G. Ackerman and David R. Beier
38. Formation of Vertebrate Limbs
Yingzi Yang
39. Skeletal Development
Peter G. Alexander, Amanda T. Boyce, and Rocky S. Tuan
VI. Endodermal Organs
40. Patterning the Embryonic Endoderm into Presumptive Organ Domains
Billie A. Moore-Scott and James M. Wells
41. Developmental Genetics of the Pulmonary System
Thomas J. Mariani
42. Pancreas Development and Stem Cells
Maureen Gannon
43. Early Liver Development and Hepatic Progenitor Cells
Jay D. Kormish and Kenneth S. Zaret
44. Intestinal Stem Cells in Physiologic Regeneration and Disease
David H. Scoville, Xi C. He, Goo Lee, Toshiro Sato, Terrence A. Barrett, and Linheng Li
1. Untangling the Gordian knot: Cell Signaling Events that Instruct Development
Philippe Soriano and Renée V. Hoch
2. Finding Gene Expression Changes using Microarray Technology
Tadayoshi Hayata and Ken W.Y. Cho
3. Chemical and Functional Genomic Approaches to Study Stem Cell Biology and Regeneration
Wen Xiong and Sheng Ding
4. Assessing Neural Stem Cell Properties using Large Scale Genomic Analysis
Soojung Shin, Jonathan D. Chesnut and Mahendra S. Rao
5. Epigenetic Influences on Gene Expression Pathways
Sundeep Kalantry and Terry Magnuson
6. New Insights into Vertebrate Origins
Billie J. Swalla
7. Understanding Human Birth Defects Through Model Organism Studies
Feyza Engin and Brendan Lee
II. Early Embryology, Fate Determination and Patterning
8. Germ Line Determinants and Oogenesis
Kelly M Haston and Renee A Reijo Pera
9. Patterning the Anterior-Posterior Axis during Drosophila Embryogenesis
Kristy L. Kenyon
10. Anterior-Posterior Patterning in Mammals
Sigolène M. Meilhac
11. Signaling Cascades, Gradients, and Gene Networks in Dorsal/Ventral Patterning
Girish S. Ratnaparkhi and Albert J. Courey
12. Early Development of Epidermis and Neural Tissue
Keiji Itoh and Sergei Y. Sokol
13. Formation of the Embryonic Mesoderm
Lisa L. Chang and Daniel S. Kessler
14. Endoderm
Debora Sinner, James M Wells and Aaron M. Zorn
15. Notch Signaling – A Versatile Tool for the Fine Patterning of Cell Fate in Development
Ajay B. Chitnis
16. Multiple roles of T-box genes
L. A. Naiche and Virginia E. Papaioannou
III. Morphogenetic and Cell Movements
17. Gastrulation in Vertebrates
Lilianna Solnica-Krezel and Diane S. Sepich
18. Regulation of tissue separation in the amphibian embryo
Herbert Steinbeisser
19. Role of the Basement Membrane in Cell Migration
Kiyoji Nishiwaki, Kiyoji Nishiwaki and Yukihiko Kubota
20. Epithelial Morphogenesis
Ronit Wilk and Howard D. Lipshitz
21. Branching Morphogenesis of Mammalian epithelia
Jamie Davies
22. The Roles of Ephrin-Eph in Morphogenesis
Ira O. Daar
IV. Ectodermal Organs
23. Neural Cell Fate Determination
Stephen N. Sansom and Frederick J. Livesey
24. Pathfinding and Patterning of Axonal Connections
S.A Linn, S.R. Kadison and C.E. Krull
25 Retinal Development
Kathryn B. Moore and Monica L. Vetter
26. Neural Crest Determination
Roberto Mayor
27. Determination of Pre-Placodal Ectoderm and Sensory Placodes
Sally A. Moody
28. Molecular Genetics of Tooth Development
Irma Thesleff
29. The Inner Ear
Donna F. Fekete and Ulrike J. Sienknecht
30. Craniofacial Formation and Congenital Defects
S.A. Brugmann and J.A. Helms
V. Mesodermal Organs
31. Induction of the Cardiac Lineage
Andrew S. Warkman and Paul A. Krieg
32. Heart Patterning and Congenital Defects
John Belmont
33. Blood Vessel Formation
Karina Yaniv and Brant M. Weinstein
34. Blood Induction and Embryonic Formation
Xiaoying Bai and Leonard I. Zon
35. Topics in Vertebrate Kidney Formation: A Comparative Perspective
Thomas M. Schultheiss
36. Development of The Genital System
Hongling Du hugh S Taylor
37. Diaphragmatic Embryogenesis and Human Congenital Diaphragmatic Defects
Kate G. Ackerman and David R. Beier
38. Formation of Vertebrate Limbs
Yingzi Yang
39. Skeletal Development
Peter G. Alexander, Amanda T. Boyce, and Rocky S. Tuan
VI. Endodermal Organs
40. Patterning the Embryonic Endoderm into Presumptive Organ Domains
Billie A. Moore-Scott and James M. Wells
41. Developmental Genetics of the Pulmonary System
Thomas J. Mariani
42. Pancreas Development and Stem Cells
Maureen Gannon
43. Early Liver Development and Hepatic Progenitor Cells
Jay D. Kormish and Kenneth S. Zaret
44. Intestinal Stem Cells in Physiologic Regeneration and Disease
David H. Scoville, Xi C. He, Goo Lee, Toshiro Sato, Terrence A. Barrett, and Linheng Li
- Edition: 1
- Published: July 19, 2007
- Language: English
SM
Sally A. Moody
Sally A. Moody is Professor of Anatomy and Cell Biology at the George Washington University Medical Center, and a member of both the Neuroscience and Genetics programs. Prior to this appointment she was on the faculty of the Anatomy and Cell Biology Department, the Department of Neuroscience, and the Developmental Biology program at the University of Virginia. She trained in developmental neurobiology at the University of Florida’s Department of Neuroscience and the University of Utah’s Department of Neurobiology and Anatomy. Dr. Moody’s current research focuses on the cascade of interactions that instruct lineages to give rise to the frog nervous system. She has taught developmental neurobiology in the MBL "Neurobiology" course and was co-director of the "Early Development of Xenopus Laevis" course at the Cold Spring Harbor Laboratory. She has also served on many National Institute of Health advisory committees dealing with issues in developmental biology and developmental neurobiology, and served on the Board of Trustees of the Society for Developmental Biology.
Affiliations and expertise
George Washington University, Washington, DC, USA