Limited Offer
Save 50% on book bundles
Immediately download your ebook while waiting for your print delivery. No promo code needed.
Principles and Practice of Pediatric Sleep Medicine
- 3rd Edition - July 16, 2022
- Editors: Stephen H. Sheldon, Meir H. Kryger, David Gozal, Temitayo O. Oyegbile-Chidi, Craig Canapari
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 7 5 5 6 6 - 5
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 7 5 5 6 8 - 9
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 7 5 5 6 7 - 2
Globally recognized as the definitive resource for any health practitioner who treats children, Principles and Practice of Pediatric Sleep Medicine provides state-of-the-… Read more
Purchase options
Institutional subscription on ScienceDirect
Request a sales quoteGlobally recognized as the definitive resource for any health practitioner who treats children, Principles and Practice of Pediatric Sleep Medicine provides state-of-the-art information on virtually all sleep-related problems encountered in pediatric patients. Written by preeminent sleep medicine experts Drs. Stephen H. Sheldon, Meir H. Kryger, David Gozal, and Craig Canapari, this full-color 3rd Edition equips you with a complete understanding of both medical and psychiatric pediatric sleep disorders in one convenient, trustworthy resource.
- Separates content into normal and abnormal sleep for quick access to key information.
- Offers four distinct parts: Principles, Diagnosis, Clinical Practice, and an all-new two-section Atlas to support diagnostic and treatment decisions, covering both normal development and specific sleep disorders.
- Includes a new chapter on ambulatory monitoring of pediatric obstructive sleep apnea and a new, combined section covering history and differential diagnosis.
- Provides extensive, up-to-date coverage of obstructive sleep apnea diagnosis and treatment; sleep-related breathing disorders; parasomnias; evaluation and management of sleepy children; evaluation and management of circadian rhythm abnormalities; and pharmacology.
- Includes a section on scoring and assessment of sleep and related physiological events.
- Features sleep studies (polysomnography), graphs, charts, and diagrams to support the text, as well as abundantly referenced chapters to help you investigate topics further.
- An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date.
Sleep medicine specialists
- Cover image
- Title page
- Table of Contents
- Activate your eBook today!
- Copyright
- List of Contributors
- Preface
- Acknowledgment
- Part I: Principles
- 1. History of Pediatric Sleep Medicine
- Abstract
- CHAPTER HIGHLIGHTS
- Overview
- Introduction
- Development of Pediatrics as a Unique Discipline
- Development of Sleep Medicine as a Unique Discipline
- Summary
- References
- 2. Development of Sleep in Infants and Children
- Abstract
- CHAPTER HIGHLIGHTS
- Introduction
- Sleep Onset
- Wake
- Transitional Sleep
- Stage N2 Sleep
- Stage N3 Sleep
- Stage REM Sleep
- Normal Course of Evolution of Sleep Across The Night
- References
- 3. Chronobiology and Circadian Rhythm Disorders in Children and Adolescents
- Abstract
- Introduction
- The Two-Process Model
- Circadian Rhythm Sleep–Wake Disorders: Diagnosis and Treatment
- Delayed Sleep–Wake Phase Disorder
- Advanced Sleep–Wake Phase Disorder
- Irregular Sleep–Wake Rhythm Disorder
- Non–24-Hour Sleep–Wake Phase Disorder
- Conclusion
- References
- 4. Sleep During Adolescence
- Abstract
- CHAPTER HIGHLIGHTS
- Sleep-Wake Patterns
- Sleep-Wake Regulation
- Changes to Sleep-Wake Regulation Across Adolescence
- Psychosocial Context
- Acknowledgments
- References
- 5. Pharmacology of Sleep in Children
- Abstract
- CHAPTER HIGHLIGHTS
- Introduction
- General Principles for Medication Use inPediatric Insomnia
- Specific Medications Used for Pediatric Insomnia
- Summary
- References
- Key References
- Recommended Readings
- 6. Promoting Healthy Sleep Practices
- Abstract
- Introduction
- Building Safe Sleep Practices
- Adequate Sleep Duration
- Bedtime Routines and Sleep-Onset Associations
- Contributing Factors
- Summary
- References
- Part II: Diagnosis
- 7. Taking a Sleep History
- Abstract
- Introduction
- Developing a Differential Diagnosis: Process of Solving Clinical Problems
- The Physical Examination
- Other Assessments
- References
- 8. Differential Diagnosis in Pediatric Sleep Medicine
- Abstract
- Differential Diagnosis
- Pediatric Insomnia (Problem Sleeplessness)
- Excessive Daytime Sleepiness (Problem Sleepiness)
- Arousals/Awakenings
- Regularity and Duration of Sleep
- Sleep Breathing Disorders
- References
- Part III: Clinical Practice
- Section I: The Insomnia (Disorders of Initiating and Maintaining Sleep)
- 9. Sleep and Colic
- Abstract
- CHAPTER HIGHLIGHTS
- Terminology and Definitions
- Properties and “Natural Course”
- Prevalence
- Pathogenesis
- Outcome and Prognosis
- Diagnosis
- Treatment
- Infantile Colic and Sleep Problems
- References
- 10. Sleep and Gastroesophageal Reflux
- Abstract
- Introduction
- Esophageal Physiology
- Mechanisms of Gastroesophageal Reflux
- Esophageal Physiology During Sleep
- Gastroesophageal Reflux Disease
- Gastroesophageal Reflux Disease Diagnosis
- Future Directions
- Conclusions
- References
- 11. Sleep and Pain
- Abstract
- CHAPTER HIGHLIGHTS
- Introduction
- Bidirectional Relationship of Pain and Sleep
- Methods of Sleep Assessment
- Psychologic Interventions/Treatments
- Pharmacologic Interventions
- Conclusion
- References
- 12. Enuresis and Obstructive Sleep Apnea in Children
- Abstract
- Abstract
- Epidemiology
- Etiology
- Pathophysiology
- Secondary Nocturnal Enuresis
- Therapeutic Options in Children With Nocturnal Enuresis
- Summary: Clinical Implications and Future Research
- Future Research: “The Central Hypothesis”
- References
- 13. Bedtime Problems and Nightwakings
- Abstract
- CHAPTER HIGHLIGHTS
- Introduction
- Summary
- References
- 14. Attention Deficit, Hyperactivity, and Sleep Disorders
- Abstract
- Introduction
- Sleep Disturbances and Comorbidity of Neurocognitive and Behavioral Deficits
- OBJECTIVES
- Shared Neurobiology of Sleep and Wakefulness, and Regulation of Behavior and Executive Function
- Psychotropic Medications Frequently Used in Treatment of Attention-Deficit/Hyperactivity Disorder and Effects on Sleep
- Conceptualizing Attention-Deficit/Hyperactivity Disorder and Its Inherent Heterogeneity
- Primary Sleep Disorders or Conditions Associated with Attention-Deficit/Hyperactivity Disorder
- Behavioral Management of Sleep Disturbances in Youth with Attention-Deficit/Hyperactivity Disorder
- Future Directions
- References
- 15. Sleep and Its Disturbances in Autism Spectrum Disorder
- Abstract
- Introduction
- Epidemiology
- Causes of Sleep Problems in Children with ASD
- References
- 16. Metabolic Syndrome and Obesity
- Abstract
- CHAPTER HIGHLIGHTS
- Introduction
- Obesity in Children
- Sleep and the Components of Metabolic Syndrome
- Treatment of Obstructive Sleep Apnea in Obese Children
- Summary
- References
- Section II: The Hypersomnias
- 17. Narcolepsy
- Abstract
- Introduction
- Epidemiology
- Clinical Features
- Pathophysiology
- Diagnosis
- Differential Diagnosis
- Case Presentation
- Management
- Future Directions
- References
- 18. Idiopathic Hypersomnia
- Abstract
- Introduction
- Epidemiology
- Pathophysiology
- Evaluation of Sleepiness in Children
- Clinical Presentation
- Differential Diagnosis of Idiopathic Hypersomnolence
- Treatment
- Summary
- References
- 19. Kleine-Levin Syndrome and Recurrent Hypersomnias
- Abstract
- Introduction
- Clinical Characteristics
- Etiology
- Evaluation
- Treatment
- References
- 20. Posttraumatic and Post-Neurosurgical Hypersomnia
- Abstract
- References
- 21. Medication-Related Hypersomnia
- Abstract
- Introduction
- Hypersomnia
- Sleep–Wake Continuum: Anatomy and Its Substrates
- Abuse or Misuse of Prescription and Over-the-Counter Medications Contributing to Hypersomnia
- Medications That Result in Sleepiness as Either an Intended or Unintended Consequence
- Other Medications That Can Cause Daytime Sleepiness
- Complementary Alternative Medications
- Cannabinoids
- Evaluating Hypersomnia Resulting From Medications: Considerations for the Clinician
- Summary
- References
- Section III: Sleep & Breathing Disorders
- 22. Normal Respiratory Physiology During Sleep in Infants and Children
- Abstract
- Introduction
- Thoracic Cage and Pulmonary Mechanics
- Response to Mechanical Loading of the Respiratory System During Sleep
- Maintenance of Upper Airway Patency During Sleep in Normal Children
- Ventilation During Sleep in Normal Children
- Control of Ventilation During Sleep
- Normal Arousal from Sleep
- Summary
- References
- 23. Apnea of Prematurity
- Abstract
- CHAPTER HIGHLIGHTS
- Introduction
- Pathophysiology
- Relevance
- Treatment
- References
- 24. Apnea of Infancy and Apparent Life-Threatening Events
- Abstract
- Definitions of Apparent Life-Threatening Events and Brief Resolved Unexplained Events
- Relationship Between Apparent Life-Threatening Events and Sudden Infant Death Syndrome
- Should All Apparent Life-Threatening Events Infants be Admitted?
- Long-Term Follow-Up: Home Monitoring
- Impact of the New American Academy of Pediatrics Brief Resolved Unexplained Event Guidelines
- Summary
- References
- 25. Primary Snoring
- Abstract
- Primary Snoring
- Future Directions
- References
- 26. Obstructive Sleep Apnea Syndrome in Childhood: Pathophysiology and Clinical Characteristics
- Abstract
- Definitions
- Pathophysiology
- OSA and Obesity
- OSA and Asthma
- OSA and Inflammation
- OSA in Infants
- Clinical Characteristics
- Clinical Consequences of OSA
- Summary
- References
- 27. Diagnosis of Obstructive Sleep Apnea
- Abstract
- Introduction
- Nomenclature
- Clinical History
- Physical Examination
- Questionnaires
- Imaging Studies
- Airway Endoscopy
- Metabolic Testing
- Video/Audio Recordings
- Overnight Polysomnography
- Normative Polysomnographic Data
- Domiciliary Studies
- Night-to-Night Polysomnographic Variability
- Diagnostic and Event Classification
- Phenotyping/Endotyping Classification
- Ancillary Testing
- Special Considerations in Infants
- Conclusions
- References
- 28. Ambulatory Monitoring in Pediatric Obstructive Sleep Apnea
- Abstract
- CHAPTER HIGHLIGHTS
- Introduction
- Obstructive Sleep Apnea in Children
- Gold Standard for Diagnosis: In-Lab Polysomnogram (PSG)
- Factors in Diagnosis
- Can Ambulatory Monitoring Provide the Essential Elements to Diagnose Obstructive Sleep Apnea in Children?
- Portable Monitoring Classifications
- Other Monitoring Options
- Currently Experimental Noncontact Methods for Assessing Sleep-Disordered Breathing in the Home
- Children Are Not Small Adults
- Conclusion
- References
- 29. Cognitive and Behavioral Consequences of Obstructive Sleep Apnea
- Abstract
- Introduction
- Behavior
- Cognition
- Causality
- Potential Mechanisms
- Summary
- References
- 30. Cardiovascular Consequences of Obstructive Sleep Apnea
- Abstract
- Introduction
- SDB-Related Cardiac and Vascular Dysfunction
- Conclusion
- References
- 31. Metabolic Consequences of Sleep-Disordered Breathing
- Abstract
- Introduction
- Sleep Curtailment, Irregular Sleep, and Obesity
- Obesity as a Risk Factor of Obstructive Sleep Apnea
- Obstructive Sleep Apnea May Promote Obesity and Its Consequences
- References
- 32. Sleep-Disordered Breathing in Cystic Fibrosis and Asthma
- Abstract
- Sleep-Disordered Breathing in Cystic Fibrosis and Asthma
- Introduction to Cystic Fibrosis
- Factors Affecting Sleep in Cystic Fibrosis
- Polysomnography Findings in Cystic Fibrosis
- Poor Sleep Quality
- Conclusions
- Introduction to Asthma
- Asthma and Sleep-Disordered Breathing
- Pathophysiologic Overlap Between Asthma and Sleep-Disordered Breathing
- Asthma and Sleep Quality
- Conclusions
- References
- 33. Sleep-Disordered Breathing and Allergic Disorders
- Abstract
- Introduction to Allergic Disease
- Sleep-Disordered Breathing and Allergy
- Bidirectional Relationship between Sleep and Allergy
- Asthma
- Allergic Rhinitis
- Atopic Dermatitis
- Other Allergic Conditions to Consider
- Conclusion
- References
- 34. Treatment of Children with Obstructive Sleep Apnea Syndrome
- Abstract
- Introduction
- Treatment Options
- Uvulopalatopharyngoplasty
- Hypoglossal Nerve Stimulation
- Supplemental Oxygen
- Weight Loss/Role of Bariatric Surgery
- Watchful Waiting
- Summary
- References
- 35. The Otolaryngologist Approach to Obstructive Sleep Apnea
- Abstract
- CHAPTER HIGHLIGHTS
- Introduction
- History
- Physical Exam
- Medical Therapy for Obstructive Sleep Apnea in Children
- Adenotonsillectomy for Obstructive Sleep Apnea in Children
- Additional Surgical Alternatives
- Conclusions
- References
- 36. Sleep Disordered Breathing: A Dental Perspective
- Abstract
- Introduction
- Etiology of Malocclusion
- Pediatric Oral Health and Sleep
- Surgical Versus Nonsurgical Treatment Options for Pediatric SDB/OSA
- Summary and Future Considerations
- References
- 37. CPAP Therapy for OSA in Children
- Abstract
- Understanding Positive Airway Pressure Therapy
- Bi-Level Positive Airway Pressure Therapy
- Titration Studies and AutoPAP Therapy
- Safety and Benefits of Positive Airway Pressure Use for the Treatment of Childhood OSAS
- Positive Airway Pressure Adherence and Factors Affecting Positive Airway Pressure Compliance
- Device and Mask Factors
- Positive Airway Pressure Device Compliance Monitoring and a Follow-Up
- Positive Airway Pressure Desensitization
- High-Flow Nasal Cannula
- Summary
- References
- 38. Noninvasive Ventilation in Neuromuscular Disease
- Abstract
- References
- 39. Novel Pharmacologic Approaches for Treatment of Obstructive Sleep Apnea
- Abstract
- CHAPTER HIGHLIGHTS
- Introduction
- Evidence of Local Upper Airway and Systemic Inflammation in Pediatric Obstructive Sleep Apnea
- Leukotriene and Leukotriene Receptors
- Glucocorticoid Receptors and Corticosteroids in Pediatric Obstructive Sleep Apnea
- References
- 40. Congenital Central Hypoventilation Syndrome
- Abstract
- Introduction
- Pathophysiology and Neuroanatomy
- Diagnosis
- Phenotype
- Management
- Outcomes
- Recommended Resources
- References
- 41. Rapid-Onset Obesity with Hypothalamic Dysfunction, Hypoventilation, and Autonomic Dysregulation Syndrome
- Abstract
- Introduction
- Pathophysiology
- Diagnosis and Presentation
- Differential Diagnosis
- Management
- Outcomes
- Additional Considerations
- References
- Section IV: Parasomnias
- 42. Disorders of Arousal
- Abstract
- Introduction
- Clinical Description
- Pathophysiology of Disorders of Arousal
- Genetics of Disorders of Arousal
- Sleep Homeostasis and Disorders of Arousal
- Polysomnography in Disorders of Arousal
- Clinical Evaluation of Children With Disorders of Arousal
- Polysomnography
- Treatment of Children With Disorders of Arousal
- Summary
- References
- 43. REM Sleep Parasomnia in Children
- Abstract
- Introduction
- REM Sleep Behavior Disorder
- Conclusions
- References
- Section V: Movement Disorders
- 44. Restless Legs Syndrome, Periodic Leg Movements, and Periodic Limb Movement Disorder
- Abstract
- Introduction
- Symptoms and Prevalence of Restless Legs Syndrome and Periodic Limb Movement Disorder in Children
- Periodic Limb Movement Disorder and Periodic Leg Movements
- Pathophysiology of Restless Legs Syndrome/Periodic Limb Movement Disorder
- The Genetics of Restless Legs Syndrome/Periodic Limb Movement Disorder
- The Diagnosis of Restless Legs Syndrome/Periodic Limb Movement Disorder in Children
- Restless Legs Syndrome and Attention-Deficit/Hyperactivity Disorder
- Restless Legs Syndrome and Restless Sleep Disorder in Children
- Treatment and Management of Restless Legs Syndrome/Periodic Limb Movement Disorder
- References
- 45. Sleep-Related Movement Disorders
- Abstract
- Introduction
- Assessment of Rhythmic Movements Surrounding the Sleep Period
- Sleep-Related Movement Disorders
- References
- Section VI: Sleep in Medical Disorders and Special Populations
- 46. Sleep and Sleep Disorders in Children with Epilepsy
- Abstract
- Questionnaire-Based Studies on the Prevalence of Sleep Disorders in Children with Epilepsy
- Non–Rapid Eye Movement Activator and Rapid Eye Movement Neuroprotective of Interictal Epileptiform Activity and Seizures
- Sleep-Related Epilepsies
- Diagnosing Sleep-Related Epilepsy
- Effects of Vagal Nerve Stimulation on Respiration During Sleep
- Treating Sleep Disorders in Children with Epilepsy
- Conclusion
- References
- 47. Neoplasms and Sleep: Impact and Implications
- Abstract
- Introduction
- Mechanisms of Sleep Disturbance
- Excessive Daytime Sleepiness
- Insomnia
- Fatigue
- Demographic and Treatment Variables Related to Differences in Sleep Problems
- Impact of Sleep Disturbance
- Interventions
- Summary
- References
- 48. Sleep in Psychiatric Disorders
- Abstract
- Introduction
- Sleep in Early-Onset Bipolar Disorder
- Sleep in Childhood Anxiety and Related Disorders
- Shared Factors and Mechanisms of Interest for Anxiety and Related Disorders
- Psychosocial Treatment
- Pharmacologic Treatment
- References
- 49. School Start Times
- Abstract
- Chapter Highlights
- Introduction
- Conclusion
- References
- Section VII: Scoring and Assessment of Sleep and Related Physiological Events
- 50. Polysomnography and Multiple Sleep Latency Test
- Abstract
- Introduction
- Indications for Polysomnography
- Organization of Sleep Services in the Context of the Sleep Study
- Running the Polysomnogram
- The Multiple Sleep Latency Test
- Scoring and Interpreting the Data
- Summary
- References
- Part IV: Atlas
- Section I: Normal Development
- 51. The Premature Infant
- Abstract
- Introduction
- References
- 52. Infants 0–3 Months
- Abstract
- Infant at Term
- Two-Month-Old Infant
- 53. Infants 3–6 Months
- Abstract
- 4-Month-Old Infant
- 54. Infants 6–12 Months
- Abstract
- 9-Month-Old
- 55. Toddler 12 Months to 2 Years
- Abstract
- 1-Year-Old
- 2-Year-Old
- 56. Children 2–5 Years Old
- Abstract
- 4-Year-Old
- 57. School-Age Children 5–10 Years Old
- Abstract
- 9-Year-Old
- Section II: Disorders
- 58. Sleep-Related Breathing Disorders
- Abstract
- Definitions
- 59. Partial Arousal Disorders: Parasomnias
- Abstract
- NREM PARASOMNIAS
- REM SLEEP PARASOMNIAS
- 60. Central Hypersomnias
- Abstract
- Central Hypersomnias
- 61. Sleep-Related Movement Disorders
- Abstract
- Periodic Limb Movement Disorder
- 62. Sleep-Related Seizures and Epilepsy
- Abstract
- Spike and Wave Activity
- Generalized Tonic/Clonic Seizure
- Index
- Confidence is ClinicalKey
- No. of pages: 544
- Language: English
- Edition: 3
- Published: July 16, 2022
- Imprint: Elsevier
- Hardback ISBN: 9780323755665
- eBook ISBN: 9780323755689
- eBook ISBN: 9780323755672
SS
Stephen H. Sheldon
Affiliations and expertise
Professor, Pediatrics, Northwestern University Feinberg School of Medicine; Director, Sleep Medicine Center, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IllinoisMK
Meir H. Kryger
Affiliations and expertise
Professor, Pulmonary, Critical Care, and Sleep Medicine, Yale School of Medicine, New Haven, Connecticut