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Post-transcriptional Gene Regulation in Human Disease

  • 1st Edition, Volume 32 - August 12, 2022
  • Editors: Buddhi Prakash Jain, Shyamal K Goswami, Tapan Sharma
  • Language: English
  • Paperback ISBN:
    9 7 8 - 0 - 3 2 3 - 9 1 3 0 5 - 8
  • eBook ISBN:
    9 7 8 - 0 - 3 2 3 - 9 1 4 2 4 - 6

Post-transcriptional Gene Regulation in Human Disease, a new volume in the Translational Epigenetics book series, offers a thorough overview and discussion of post-transcri… Read more

Post-transcriptional Gene Regulation in Human Disease

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Post-transcriptional Gene Regulation in Human Disease, a new volume in the Translational Epigenetics book series, offers a thorough overview and discussion of post-transcriptional genetic control mechanisms and their roles across various pathologies and human developmental outcomes, along with regulatory mechanisms targeted for therapeutic approaches. The book is broadly divided in two parts: early chapters describe the basics of post-transcriptional gene regulation, associated epigenetic mechanisms, the role of RNA binding proteins, the evolution of post-transcriptional gene regulation, and methods to study these mechanisms. The second half of the book includes deeper discussion of post-transcriptional gene regulation across specific diseases and therapeutics targets. Various post-transcriptional events, including alternative splicing and polyadenylation, mRNA stability, and miRNAs and their involvement in the disease progression, are examined in detail.