
Polymeric Nanosystems
Theranostic Nanosystems, Volume 1
- 1st Edition - March 22, 2023
- Editors: Md Saquib Hasnain, Amit Kumar Nayak, Tejraj M. Aminabhavi
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 8 5 6 5 6 - 0
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 8 8 5 7 7 - 5
Polymeric Nanosystems: Theranostic Nanosystems, Volume One examines the applications of nanotherapeutic systems and nanodiagnostics in relation to polymeric nanosystems. In the la… Read more

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Request a sales quotePolymeric Nanosystems: Theranostic Nanosystems, Volume One examines the applications of nanotherapeutic systems and nanodiagnostics in relation to polymeric nanosystems. In the last decade, numerous biopolymers have been utilized to prepare polymeric nanosystems for therapeutic applications. These biopolymers include polylactic acid, polylactide-co-glycolide, polycaprolactone, acrylic polymers, cellulose and cellulose derivatives, alginates, chitosan, gellan gum, gelatin, albumin, chontroitin sulfate, hyaluronic acid, guar gum, gum Arabic, gum tragacanth, xanthan gum, and starches. Besides these biopolymers, grafted polymers are also being used as advanced polymeric materials to prepare many theranostic nanocarriers and nanoformulations. This book explores the array of polymeric nanosystems to understand therapeutic potentials.
It will be useful to pharmaceutical scientists, including industrial pharmacists and analytical scientists, health care professionals, and regulatory scientists actively involved in the pharmaceutical product and process development of tailor-made polysaccharides in drug delivery applications.
- Contains in-depth discussions of the polymeric nanosystems including high-quality graphics, flowcharts, and graphs for enhanced understanding
- Reviews the literature on polymeric nanosystems while also suggesting new avenues
- Includes contributions in all areas of polymeric nanosystems, providing a thorough and interdisciplinary work
- Cover image
- Title page
- Table of Contents
- Copyright
- List of contributors
- Preface
- Chapter 1. Polymer-based nanotheranostics: current status and challenges
- Abstract
- Abbreviations
- 1.1 Introduction
- 1.2 Polymeric theranostics
- 1.3 Polymers for nanotheranostics
- 1.4 Concluding remarks, future implications, and prospects
- References
- Chapter 2. Poly(lactic acid) and poly(lactic-co-glycolic acid)-based nanocarrier systems for theranostic applications
- Abstract
- 2.1 Introduction
- 2.2 Chemistry of polylactic acid and poly(lactic-co-glycolic acid)
- 2.3 Polylactic acid-based nanocarrier systems for theranostic applications
- 2.4 PLGA-based nanocarrier systems for theranostic applications
- 2.5 Conclusion and future prospects
- References
- Chapter 3. Polycaprolactone-based nanoparticles for advanced therapeutic applications
- Abstract
- 3.1 Introduction
- 3.2 Physicochemical properties of poly-ε-caprolactone
- 3.3 Methods for preparation of poly-ε-caprolactone nanoparticles
- 3.4 Poly-ε-caprolactone nanoparticles for various advanced therapeutic applications
- 3.5 Conclusion
- References
- Chapter 4. Acrylate-based polymeric nanotheranostics
- Abstract
- 4.1 Introduction
- 4.2 Mechanism of targeted drug delivery systems in cancer
- 4.3 Passive targeting
- 4.4 Active targeting
- 4.5 Polymeric nanomedicines and nanotheranostics systems for drug delivery
- 4.6 Acrylate-based polymers for theranostic applications
- 4.7 Final remarks and conclusions
- References
- Chapter 5. Cellulose and cellulose derivatives-based nanosystems as therapeutic platform
- Abstract
- 5.1 Introduction
- 5.2 Types of cellulose
- 5.3 Application of cellulose and its derivatives-based nanosystems on nanotheranostics
- 5.4 Limitations and prospects
- 5.5 Conclusion
- References
- Chapter 6. Alginate-based nanosystems for therapeutic use
- Abstract
- 6.1 Introduction
- 6.2 Alginate delivery system
- 6.3 Conclusion
- References
- Further reading
- Chapter 7. Chitin- and chitosan-based nanomaterials for therapeutic applications
- Abstract
- 7.1 Introduction
- 7.2 Sources and chemical structure of chitin and chitosan
- 7.3 Extraction of chitin and chitosan
- 7.4 Therapeutic applications
- 7.5 Conclusion
- References
- Chapter 8. Gellan gumbased nanosystems for therapeutic applications
- Abstract
- 8.1 Introduction
- 8.2 The history of Gellan gum
- 8.3 General principals of Gellan
- 8.4 Properties of Gellan gum
- 8.5 Advantages and disadvantages of Gellan gum
- 8.6 Factors affected by Gellan gum drug delivery
- 8.7 Gellan gum drug route administration
- 8.8 Gellan gum used as nanosystem drug delivery
- 8.9 Applications of Gellan gum
- 8.10 In vitro evaluation of Gellan gum formulations
- 8.11 Gellan gum nanosystem drug delivery in comparison with conventional drugs
- 8.12 New approaches to Gellan gum-based nanosystems for therapeutic applications
- References
- Chapter 9. Chondroitin sulfate-derived theranostic nanosystems
- Abstract
- 9.1 Introduction
- 9.2 Chondroitin sulfate-based nanosystems
- 9.3 Conclusion and perspective
- References
- Chapter 10. Hyaluronic acid-based nanosystems for theranostic delivery and imaging
- Abstract
- 10.1 Introduction
- 10.2 Properties of hyaluronic acid
- 10.3 Hyaluronic acid-drug conjugates
- 10.4 Hyaluronic acid-based hydrogel
- 10.5 Hyaluronic acid-based drug delivery systems
- 10.6 The role of hyaluronic acid-based nanosystems in imaging
- 10.7 The role of hyaluronic acid-based nanosystems in therapy
- 10.8 Theranostic delivery for hyaluronic acid-based nanosystems
- 10.9 Conclusion
- References
- Chapter 11. Pullulan-based nanocarriers for therapeutic applications
- Abstract
- 11.1 Introduction
- 11.2 Therapeutic applications of pullulan and its derivatives
- References
- Chapter 12. Xanthan gum-based nanocarriers for therapeutic delivery
- Abstract
- 12.1 Introduction
- 12.2 Xanthan gum: source, chemical composition, properties, and uses
- 12.3 Synthesis of xanthan gum-based hydrogels
- 12.4 Application of xanthan gum-based hydrogels in therapeutic delivery
- 12.5 Miscellaneous applications of xanthan gum-based systems
- 12.6 Conclusion and future perspectives
- Acknowledgments
- Conflicts of interest
- References
- Chapter 13. Gum tragacanth-based nanosystems for therapeutic applications
- Abstract
- 13.1 Nanomedicine
- 13.2 Gum tragacanth
- 13.3 Production and collection of gum tragacanth
- 13.4 Structure of gum tragacanth
- 13.5 Rheological characteristics
- 13.6 Degradation
- 13.7 Cytotoxicity
- 13.8 Applications of gum tragacanth
- 13.9 Nanotechnology
- 13.10 Nanoparticle applications
- 13.11 Nanohydrogels
- 13.12 Nanoencapsulation
- 13.13 Nanofibers
- 13.14 Conclusion
- References
- Chapter 14. Pectin-based nanoformulations for therapeutic applications
- Abstract
- 14.1 Introduction
- 14.2 Nanoformulation of pectin
- 14.3 Therapeutic applications of nano-pectin
- 14.4 Conclusions
- References
- Chapter 15. Guar-gum-based nanocarriers for drug delivery and targeting
- Abstract
- 15.1 Introduction
- 15.2 Extraction of guar-gum
- 15.3 Guar gum productions
- 15.4 Various properties of natural Guar-gum polymer
- 15.5 Guar-gum-based nanocarriers for drug delivery applications
- 15.6 Conclusions and prospects
- Acknowledgment
- References
- Chapter 16. Carrageenan-based nanosystems for therapeutic applications
- Abstract
- 16.1 Introduction
- 16.2 Carrageenan-based nanosystems
- 16.3 Therapeutic application of carrageenan-based nanosystem
- 16.4 Conclusion and future perspective
- References
- Chapter 17. Starch-based nanosystems for theranostic applications
- Abstract
- 17.1 Introduction
- 17.2 Starch-based nanosystems
- 17.3 Starch nanoparticles
- 17.4 Starch nanocrystals
- 17.5 Nutrients and nutraceutical encapsulation
- 17.6 Encapsulation of pharmaceuticals
- 17.7 Conclusion
- References
- Chapter 18. Gelatin-based nanosystems for therapeutic applications
- Abstract
- 18.1 Introduction
- 18.2 Gelatin nanosystems: methods of production
- 18.3 Gelatin-based nanosystems applications
- 18.4 Conclusions and future perspectives
- References
- Chapter 19. Albumin-based nanocarriers for therapeutic applications
- Abstract
- 19.1 Introduction
- 19.2 Albumin-types and structures
- 19.3 Albumin-based nanocarriers
- 19.4 Surface functionalization of albumin nanocarriers and applications
- 19.5 Applications of albumin nanocarriers
- 19.6 Clinical translation of albumin-based nanocarriers
- 19.7 Conclusion
- Acknowledgments
- References
- Chapter 20. Silk protein-based nanoparticles for therapeutic applications
- Abstract
- 20.1 Introduction
- 20.2 Therapeutic presentations of sericin nanoparticles
- 20.3 Sericin nanoparticles in wound healing and corneal wound healing
- 20.4 Sericin nanoparticle in cancer therapy
- 20.5 Sericin nanoparticles in cardiotherapy
- 20.6 Sericin nanoparticles in CNS disorders
- 20.7 Sericin nanoparticles as potential antioxidant
- 20.8 Sericin nanoparticles as potential drug carriers
- 20.9 Therapeutic presentations of fibroin nanoparticles
- 20.10 Fibroin-based nanoparticles for drug delivery
- 20.11 Fibroin nanoparticles in tissue engineering
- 20.12 Fibroin nanoparticles for protein delivery
- 20.13 Fibroin nanoparticles in gene delivery
- 20.14 Fibroin nanoparticles in enzyme immobilization
- 20.15 Fibroin nanocomposites for biomedical applications
- 20.16 Fibroin nanoparticles for nerve regeneration
- 20.17 Fibroin nanoparticles for biosensing and bioimaging
- 20.18 Conclusions and future perspectives
- References
- Chapter 21. Zein-based nanoparticles for drug delivery and targeting
- Abstract
- 21.1 Introduction
- 21.2 Preparation methods of zein NPs and their stability
- 21.3 Oral administration of zein NPs to the intestinal tract
- 21.4 Zein-based nanoformulations in cancer treatment
- 21.5 Polysaccharide modification of zein NPs to deliver drugs to cancer cells
- 21.6 Zein-modification with other proteins to develop anticancer drug delivery means
- 21.7 Zein-based delivery of active substances against diabetes type II
- 21.8 Zein-based NPs as antiinflammatory delivery means
- 21.9 Zein-based nanoformulations as antimicrobial means
- 21.10 Analysis of α-zein peptides reveals some extra features
- 21.11 Conclusion
- Acknowledgement
- References
- Chapter 22. Casein-based nanosystems for therapeutic applications
- Abstract
- 22.1 Introduction to nanotechnology
- 22.2 Protein-based nanoparticles
- 22.3 Background of casein
- 22.4 Structural aspects of casein
- 22.5 Casein-based nanoparticles
- 22.6 Synthesis of casein-based nanoparticles
- 22.7 Therapeutic applications of casein-based nanoparticles
- 22.8 Toxicity of casein-based nanoparticles
- 22.9 Future perspectives and challenges
- 22.10 Conclusion
- Acknowledgment
- References
- Chapter 23. Polymeric nanosystems for cancer theranostics
- Abstract
- 23.1 Introduction
- 23.2 Polymer-based nanosystems for theranostic application
- 23.3 Multifunctionality of polymers nanostructures for theranostic application
- 23.4 Actively targeted polymer nanoparticles for theranostic application
- 23.5 Polymeric nanoparticles for both therapy and imaging application
- 23.6 Conclusion
- References
- Chapter 24. Polymeric nanosystems for cardiovascular therapeutics
- Abstract
- 24.1 Introduction
- 24.2 Polymeric nanosystem
- 24.3 Potential biocompatibility
- 24.4 Easy functionality
- 24.5 Passive and active targeting
- 24.6 Polymeric nanosystems for the treatment of cardiovascular system
- 24.7 Liposomes
- 24.8 Dendrimers
- 24.9 Polymeric nanoparticles
- 24.10 Nanoparticles
- 24.11 Nanotechnology and hypertensive disease
- 24.12 Application of nanotechnology in pulmonary hypertension
- 24.13 Application of nanotechnology in acute myocardial infarction treatment
- 24.14 Future perspective and conclusion
- Acknowledgments
- Author disclosure statement
- References
- Chapter 25. Polymeric nanosystems for neurological therapeutics
- Abstract
- 25.1 Introduction
- 25.2 Polymeric nanosystems
- 25.3 Conclusions and future perspective
- References
- Chapter 26. Polymeric nanosystems for antidiabetic therapeutics
- Abstract
- 26.1 Introduction
- 26.2 Conclusions
- References
- Chapter 27. Molecular imprinting and surface grafting of glycoprotein fragments in polymeric nanosystems: from cancer diagnosis to virus targeting
- Abstract
- 27.1 Introduction
- 27.2 Glycoproteins, glycans, and monosaccharides and their roles in biology
- 27.3 Tailoring of polymers to medical applications
- 27.4 Molecular imprinting and grafting in synthetic materials
- 27.5 Application with labeling, imaging, and development of cancer therapies
- 27.6 Application with antiviral polymers
- Acknowledgments
- References
- Index
- No. of pages: 908
- Language: English
- Edition: 1
- Published: March 22, 2023
- Imprint: Academic Press
- Paperback ISBN: 9780323856560
- eBook ISBN: 9780323885775
MH
Md Saquib Hasnain
AN
Amit Kumar Nayak
Dr. Amit Kumar Nayak (MPharm, PhD) is working as a professor, at the Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha ‘O' Anusandhan (Deemed to be University), Odisha, India. He has earned his PhD from IFTM University, Moradabad, Uttar Pradesh, India. He has over 14 years of research experiences in the field of pharmaceutics, especially in the development and characterization of novel biopolymeric and nanostructured drug delivery systems. Till date, he has authored more than 138 research and review publications in various high-impact peer-reviewed journals and 135 book chapters. He has edited/authored 23 international books to his credit. Dr. Nayak has presented his research work at several conferences. He has received University Foundation Day Research Award, 2019 and 2022 by Biju Patnaik University of Technology, Odisha. Dr. Nayak is a life member of the Association of Pharmaceutical Teachers of India (APTI) and a registered pharmacist.
TA
Tejraj M. Aminabhavi
Tejraj M. Aminabhavi is the Director of Research at the Center for Energy and Environment , School of Advanced Sciences, KLE Technological University, Hubballi, India. He works in the area of membrane transport processes, molecular modeling of polymer surfaces, wastewater treatment technologies, drug delivery polymers and sustainable environmental engineering.