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Polymeric Biomaterials for Healthcare Applications

1st Edition - May 7, 2022

Editor: Kokkarachedu Varaprasad

Paperback ISBN:

9 7 8 - 0 - 3 2 3 - 8 5 2 3 3 - 3

eBook ISBN:

9 7 8 - 0 - 3 2 3 - 8 5 2 3 4 - 0

Polymeric Biomaterials for Healthcare Applications details a broad range of polymeric biomaterials, methods of synthesis and preparation, and their various applications in… Read more

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Polymeric Biomaterials for Healthcare Applications details a broad range of polymeric biomaterials, methods of synthesis and preparation, and their various applications in healthcare and biomedicine. The book provides a fundamental overview of polymers and processing technologies to allow clinical scientists to explore the use of these polymers in alternative applications. A wide variety of healthcare applications are covered, including treatment for autoimmune diseases and bacterial infections, tissue engineering, gene delivery, wound dressing, and more. The book provides a core introductory text for clinical and materials scientists new to the area of polymeric biomaterials.

This book will prove useful to academics and researchers in materials science, biomedical engineering, clinical science and pharmaceutical science.

Cover image
Title page
Table of Contents
Copyright
List of contributors
1. The importance of polymers in the preparation of medical devices for human body applications
Abstract
1.1 Introduction
1.2 Polyethylene
1.3 Polypropylene
1.4 Polyurethanes
1.5 Polyvinylidene fluoride
1.6 Poly(dimethyl siloxane)
1.7 Polyamide
1.8 Carbon nanotube-based polymeric composites
1.9 Poly(methyl methacrylate)
1.10 The effects of sterilization on medical devices
1.11 Conclusion and prospects
Acknowledgments
References
2. Polymeric beads for targeted drug delivery and healthcare applications
Abstract
2.1 Introduction
2.2 Some preparation protocols of polymeric beads
2.3 Targeted drug encapsulation of polymeric beads for drug delivery
2.4 Anti-human immunodeficiency virus drugs
2.5 Polymeric beads for wound dressing
2.6 Sterilization methods used for polymeric beads
2.7 Other medical applications of beads
2.8 Polymeric beads for miscellaneous applications
2.9 Vaccine delivery
2.10 Conclusion
Acknowledgments
References
3. Polymer nanoparticles (nanomedicine) for therapeutic applications
Abstract
3.1 Introduction
3.2 Polymeric nanoparticles
3.3 Characteristics of polymeric nanoparticles
3.4 Characterization of polymeric nanoparticles
3.5 Synthesis of polymeric nanoparticles
3.6 Solvent evaporation
3.7 Salting out
3.8 Nanoprecipitation
3.9 Dialysis
3.10 Supercritical fluid technology
3.11 Polymerization methods
3.12 Biomedical applications of polymeric nanoparticles
3.13 Challenges and conclusion
3.14 Conclusion
References
4. Polymers used in green synthesis of nanoparticles and their importance in pharmaceutical and biomedical applications
Abstract
4.1 Introduction
4.2 Significance of polymers for the green synthesis of metal nanoparticles
4.3 Polymers used in green synthesis of metal nanoparticles
4.4 Polymeric networks in green synthesis of metal nanoparticles
4.5 The importance of the sterilization process
4.6 Wound dressing
4.7 Anticancer applications
4.8 Conclusions and future perspectives
Acknowledgments
References
5. Biopolymer-based biodegradable biomaterials for in vivo and in vitro biomedical applications
Abstract
5.1 Introduction
5.2 Uses and preparation of biopolymer-based biomaterials for tissue-engineering applications
5.3 Importance of sterilization for biodegradable polymers
5.4 Future scope for biodegradable biomaterials
5.5 Future use of biodegradable biomaterials
5.6 Conclusion
References
6. A glimpse of biomedical application potential of biodegradable polymers for anticancer drug delivery
Abstract
6.1 Introduction
6.2 Classification of biodegradable polymers
6.3 Stimulus-based release from a biodegradable polymer
6.4 Characterization of polymeric nanocarrier systems
6.5 Targeted drug delivery
6.6 Applications
6.7 Theranostic applications
6.8 Patents on biodegradable polymeric drug delivery systems
6.9 Conclusion and future perspectives
Acknowledgment
Conflict of interest
References
7. The importance of polymers in the preparation of biomaterials for removal of metal and control of bacterial infections for healthcare applications
Abstract
7.1 Introduction
7.2 Polysaccharides for metal ion removal from water
7.3 Polysaccharides for healthcare applications
7.4 Polysaccharide-metal composites: biocompatible materials with biocide activity and their applications in the medical field
7.5 Future use and perspective
7.6 Conclusion
Acknowledgments
References
8. Functionalization of biopolymer keratin-based biomaterials and their absorption properties for healthcare application
Abstract
8.1 Introduction
8.2 History and classification
8.3 Types of bonding in keratin
8.4 Functionalization of keratin
8.5 Absorption properties of keratin
8.6 Healthcare applications of keratin biomaterials
8.7 Future prospects of keratin biopolymer
8.8 Conclusions
References
9. Controlling the toxicity of antibiotics and metal nanoparticles by using polymers for the treatment of bacterial infection for medical applications
Abstract
9.1 Introduction
9.2 Advantages and disadvantages of antimicrobial polymers
9.3 Physicochemical properties
9.4 Targeted polymer-antibiotic conjugates
9.5 Treatment for drug-resistant bacteria
9.6 Sterilization process
9.7 Future use of polymers in healthcare
9.8 Conclusion
References
10. The efficacy of injectable biomaterials for wound care, orthopedic application, and tissue engineering
Abstract
10.1 Introduction
10.2 Synthesis methods of injectable hydrogels and properties
10.3 Chemical crosslinking methods
10.4 Physical crosslinking methods
10.5 Biomaterials used for the development of injectable hydrogels and their advantages
10.6 Injectable hydrogels for wound care and skin regeneration
10.7 Injectable hydrogels for the treatment of arthritis
10.8 Injectable hydrogels for bone regeneration
10.9 Injectable hydrogels for cartilage regeneration
10.10 Injectable hydrogels for tendon repair
10.11 Injectable hydrogels for vascular regeneration
10.12 Sterilization process for injectable biomaterials
10.13 Conclusion
Acknowledgments
References
11. Temperature-sensitive polymers for biomaterials for drug delivery, gene delivery, and tissue engineering
Abstract
11.1 Introduction
11.2 Application and properties of thermosensitive polymers in drug delivery
11.3 Application and properties of thermosensitive polymers in gene delivery
11.4 Application and properties of thermosensitive polymers in tissue engineering
11.5 Conclusion and future prospectives
References
12. Development of medical polymers for applications in neurological disorders
Abstract
12.1 Introduction
12.2 Chitosan
12.3 Poly(lactic-co-glycolic acid)
12.4 Alginate
12.5 Alzheimer’s disease
12.6 Parkinson’s disease
12.7 Conclusions and future prospects
References
13. Polymeric materials for autoimmune diseases
Abstract
13.1 Introduction
13.2 Synthetic and natural polymers for autoimmune diseases
13.3 Conclusion and future prospects
Acknowledgments
References
Index