Poly(lactic-co-glycolic acid) (PLGA) Nanoparticles for Drug Delivery
- 1st Edition - March 2, 2022
- Imprint: Elsevier
- Editor: Prashant Kesharwani
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 9 1 2 1 5 - 0
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 1 4 3 1 - 4
Poly(lactic-co-glycolic acid) (PLGA) Nanoparticles for Drug Delivery is a comprehensive guide to PLGA nanoparticles for targeting various diseases, covering principles, formation… Read more
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Request a sales quotePoly(lactic-co-glycolic acid) (PLGA) Nanoparticles for Drug Delivery is a comprehensive guide to PLGA nanoparticles for targeting various diseases, covering principles, formation, characterization, applications, regulations and the latest advances. Sections introduce the fundamental aspects of PLGA nanoparticles for drug delivery, including properties, preparation methods, characterization, drug loading methods, and drug release mechanisms, along with a focus on applications. Application of PLGA nanoparticles for the treatment of cancer, inflammatory, cerebral, cardiovascular, and infectious diseases, as well as in regenerative medicine, photodynamic and photothermal therapy, and gene therapy, are all explained in detail.
The final chapters explore recent advances and regulatory aspects. This book is a valuable resource for researchers and advanced students across nanomedicine, polymer science, bio-based materials, chemistry, biomedicine, biotechnology, and materials engineering, as well as for industrial scientists and R&D professionals with an interest in nanoparticles for drug delivery, pharmaceutical formulations and regulations, and development of innovative biodegradable materials.
- Presents the fundamentals of PLGA nanoparticles, including properties, preparation, characterization, and biofate and cellular interactions
- Provides in-depth coverage of a broad range of specific applications of PLGA nanoparticles across disease treatment, regenerative medicine and therapeutic areas
- Offers a methodical approach to PLGA nanoparticles in drug delivery that is supported by data tables, illustrative figures and flowcharts
Researchers and advanced students in nanoparticles, nanomedicine, polymer science, bio-based materials, chemistry, biomedicine, biotechnology, and materials engineering, Scientists, R&D professionals, and clinicians with an interest in pharmaceutical formulations and regulations, and development of innovative plant-derived materials
PART A Synthesis and characterization of PLGA nanoparticles for drug delivery
1. History, introduction, and properties of PLGA nanoparticles as drug delivery carriers
Gulsel Yurtdas¸ Kirimlio>glu
2. Preparation and characterization of PLGA nanoparticles
Raphaël Cornu, Gautier Laurent, and Arnaud Beduneau
3. Drug loading methods and mechanism of drug release from PLGA nanoparticles
Gulsel Yurtdas¸ Kirimlio>glu
4. Biofate and cellular interactions of PLGA nanoparticles
Letícia Bueno Macedo, Cristiane Franco Codevilla, Daniela Mathes, Bianca Costa Maia,
Clarice Madalena Bueno Rolim, and Daniele Rubert Nogueira-Librelotto
PART B Application of PLGA nanoparticles in drug delivery
5. Targeting strategies using PLGA nanoparticles for efficient drug delivery
Priyanka Sharma, Navneet Kaur, and Asifkhan Shanavas
6. Current progress in PLGA-based nanoparticles for treatment of cancer diseases
Irem Karasu, Sedenay Akbas¸, and Yılmaz Çapan
7. PLGA-based nanoparticles for enhanced diagnosis and cancer therapy
Archana Kumari, Arijit Mal, Roly Yogendra Kaushik, and Rajdip Bandyopadhyaya
8. PLGA-based nanoparticles for the treatment of inflammatory diseases
Deepti Singh, Mohammad Afsar Khan, and Hifzur R. Siddique
9. PLGA-based nanoparticles for treatment of cerebral diseases
Juna Brigit Chacko and Sajan Jose
10. PLGA-based nanoparticles for treatment of cardiovascular diseases
JulyanaNoval de Souza Ferreira, VannylaViktória Viana Vasconcelos, Barbara Silva Figueiredo,
Demian Paiva Alves, Antony Luca Luna Vieira de Abreu, Priscila Ponate de Souza,
Dayana Laura Nascimento Costa, and Andre Romero da Silva
11. PLGA-based nanoparticles for treatment of infectious diseases
Johannes Buescher, Armin Walter Novak, Saeed Ahmed Khan, Agnes-Valencia Weiß, Sangeun Lee, and Marc Schneider
12. PLGA-based nanoparticles as regenerative medicine
Deepika Sharma, Smruti Rekha Rout, Gowtham Kenguva, Mahender Khatravath, Gaurav K. Jain, Geeta Aggarwal, Prashant Kesharwani, and Rambabu Dandela
13. Photodynamic and photothermal therapy using PLGA nanoparticles
Deepak Dinakaran, Abul Kalam Azad, and Brian C. Wilson
14. Gene therapy using PLGA nanoparticles
Smruti Rekha Rout, Gowtham Kenguva, Deepika Sharma, Amirhossein Sahebkar, Vidhu Aeri, Prashant Kesharwani, and Rambabu Dandela
PART C Recent advances and regulatory aspects in PLGA nanoparticles
15. Hybrid PLGA nanoparticles as advanced drug delivery and theranostic applications
Hayrettin Tonbul and Yılmaz Çapan
16. Clinical translation of PLGA nanoparticles into the market
Khushboo Jani and Neeraj Kaushal
17. Biological toxicity and environmental hazards associated with PLGA nanoparticles
Zachary R. Stromberg, Daniel E. Jacobsen, Philip A. Kocheril, and Jessica Z. Kubicek-Sutherland
18. PLGA nanoparticles: Current uses and emerging trends
Itaciara Larroza Nunes, Flávia Barbosa Schappo, Larissa Santos Assuncão, and Camila Duarte Ferreira Ribeiro
- Edition: 1
- Published: March 2, 2022
- No. of pages (Paperback): 532
- Imprint: Elsevier
- Language: English
- Paperback ISBN: 9780323912150
- eBook ISBN: 9780323914314
PK
Prashant Kesharwani
Dr. Prashant Kesharwani is assistant professor of Pharmaceutics at Department of Pharmaceutical Sciences, Dr. Harisingh Gour Vishwavidyalaya, Sagar, Madhya Pradesh, India. He has more than 12 years of teaching, research, and industrial experience at international levels from various countries, including the United States, Malaysia, and India. An overarching goal of his current research is the development of nanoengineered drug delivery systems for various diseases. He has more than 350 international publications in well-reputed journals and more than 25 international books (Elsevier). He is a recipient of many research grants from various funding bodies. He is also the recipient of several internationally acclaimed awards, such as “USERN Laureate award”, most prestigious “SERB-Ramanujan Fellowship Award”. He actively participates in outreach and scientific dissemination for the service of the wider community. His Number of citations is = 26779; h-index = 85; i-10 index = 370 (According to google scholar on March 2025). He has more than 30 international publications published in very high impact factor journals (Progress in Polymer Sciences IF 32.063, Molecular Sciences IF 41.444, Progress in Material Sciences IF 48.580, Advanced Materials IF 29.4, Drug Resistance Update IF 22.841 and Material Todays IF 32.072). He has presented many invited talks and oral presentations at prestigious scientific peer-conferences, received international acclaims and awards for research contribution, supervised students/junior researchers and actively participated in outreach and scientific dissemination for the service of the wider community.
Affiliations and expertise
Department of Pharmaceutical Sciences, Dr. Harisingh Gour Vishwavidyalaya, Sagar, Madhya Pradesh, IndiaRead Poly(lactic-co-glycolic acid) (PLGA) Nanoparticles for Drug Delivery on ScienceDirect