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Pili in Mycobacterium Tuberculosis
Structure, Function, and Therapeutic Advances
- 1st Edition - June 27, 2024
- Authors: Ali Akbar Velayati, Parissa Farnia
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 2 1 7 1 2 - 8
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 1 7 1 3 - 5
Pili in Mycobacterium Tuberculosis: Structure, Function, and Therapeutic Advances discusses the types of pili produced by the tuberculosis-causing bacterium, Mycobacterium tuberc… Read more
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Request a sales quotePili in Mycobacterium Tuberculosis: Structure, Function, and Therapeutic Advances discusses the types of pili produced by the tuberculosis-causing bacterium, Mycobacterium tuberculosis (MTB). The book examines the structure of pili shown under electron and atomic force microscopy and, by using whole genome sequencing, outlines the importance of pili in MTB. It also explores the role of pili in bacteria–host interactions and in drug development and delivery.
The book provides an overview of the structure, synthesis, and function of pili in bacteria. This includes taxonomy and the role of pili in diseases. It also examines the structure of pili and the preparation of MTB for electronic and atomic microscopy. It explores the various life cycles of pili, the susceptibility patterns of MTB, the differences of pili formation in MTB, and their role in increase surveillance. It goes on to discuss the expression and function of pili using whole genome sequencing and PCR-based methods and delves into bacteria–host interactions. Lastly, it explores the development of new drugs and their therapeutic delivery by pili.
The book provides an overview of the structure, synthesis, and function of pili in bacteria. This includes taxonomy and the role of pili in diseases. It also examines the structure of pili and the preparation of MTB for electronic and atomic microscopy. It explores the various life cycles of pili, the susceptibility patterns of MTB, the differences of pili formation in MTB, and their role in increase surveillance. It goes on to discuss the expression and function of pili using whole genome sequencing and PCR-based methods and delves into bacteria–host interactions. Lastly, it explores the development of new drugs and their therapeutic delivery by pili.
- Covers the structure, synthesis, and function of pili produced by the tuberculosis-causing bacterium, MTB
- Introduces seven types of pili in MTB
- Explains the mechanism of bacteria–host attachment and importance of this phenomena in MTB pili and other bacteria
- Emphasizes the use of advances techniques to study and investigate the TB-bacilli and its interaction with host cells
Researchers in microbiology involved in the study of mycobacteriology and the MTBC bacteria, particularly those interested in researching pili in Mycobacterium tuberculosis Researchers working in antibiotics development, vaccine development, and host-directed therapy
- Cover image
- Title page
- Table of Contents
- Copyright
- Dedication
- About the authors
- Chapter 1. The structure and function of pili in bacteria
- Abstract
- 1.1 The taxonomy of the genus Mycobacterium
- 1.2 Different pili in bacteria genies
- 1.3 The pili at genomic level
- 1.4 The role and function of pili in diseases
- References
- Further reading
- Chapter 2. The structure of pili under electron and atomic force microscopy
- Abstract
- 2.1 Preparation of Mycobacterium tuberculosis for electron microscopy
- 2.2 Preparation of Mycobacterium tuberculosis for atomic force microscopy
- 2.3 Preparation of different life cycle and susceptibility pattern of Mycobacterium tuberculosis
- 2.4 Differences of pili formation in Mycobacterium tuberculosis and their role in increase surveillance
- References
- Further reading
- Chapter 3. The pili at genomic level
- Abstract
- 3.1 Whole genome of Mycobacterium tuberculosis
- 3.2 Genes related to pili expression and function in tuberculosis and other Mycobacterium species
- References
- Further reading
- Chapter 4. The design for drug delivery using pili in Mycobacterium tuberculosis
- Abstract
- 4.1 Pili application in drug delivery in different bacteria
- 4.2 Pili application in drug delivery in mycobacteria
- References
- Further reading
- Chapter 5. Role of Mycobacterium tuberculosis pili in host
- Abstract
- 5.1 The role of bacteria pili in host
- 5.2 Role of Mycobacterium tuberculosis pili in host
- References
- Further reading
- Index
- No. of pages: 340
- Language: English
- Edition: 1
- Published: June 27, 2024
- Imprint: Academic Press
- Paperback ISBN: 9780443217128
- eBook ISBN: 9780443217135
AV
Ali Akbar Velayati
Dr. Ali Akbar Velayati is the Director of the National Research Institute of Tuberculosis and Lung Diseases (NRITLD) at the Shahid Beheshti University of Medical Sciences. He is a Full Professor of Pediatric Infectious Diseases, and he has guided more than 300 MD and PhD students. He is also the Head of Mycobacteriology Research Center (MRC) in NRITLD, where he directly monitors the basic and clinical trial on tuberculosis. Dr. Velayati is the President of the Asian African Society of Mycobacteriology and of the Society of Biomedical and Biotechnology Scientists. He is the Chief Editor of the International Journal of Mycobacteriology, the Journal of Preventive, Diagnostic and Treatment Strategies in Medicine, and the Biomedical and Biotechnology Research Journal.
Affiliations and expertise
Mycobacteriology Research Center (MRC) and Director, National Research Institute of Tuberculosis and Lung Disease (NRITLD), WHO Collaborating Centre, Shahid Beheshti University of Medical Sciences, Tehran, IranPF
Parissa Farnia
Dr. Parissa Farnia is the Director of the Iranian National Reference Tuberculosis Laboratory (INRT) at the Mycobacteriology Research Center (MRC) in the National Research Institute of Tuberculosis and Lung Disease (NRITLD). Her expertise and research interests include mycobacteriology, infectious diseases, and tuberculosis. She has published in multiple international journals such as Journal of Clinical Microbiology, Chest, Clinical infectious Diseases, and the International Journal of Tuberculosis and Lung Disease and serves on several editorial boards including International Journal of Mycobacteriology, the Journal of Preventive, Diagnostic and Treatment Strategies in Medicine, and the Biomedical and Biotechnology Research Journal.
Affiliations and expertise
Mycobacteriology Research Center (MRC), National Research Institute of Tuberculosis and Lung Disease (NRITLD), WHO Collaborating Centre, Shahid Beheshti University of Medical Sciences, Tehran, IranRead Pili in Mycobacterium Tuberculosis on ScienceDirect