Pili in Mycobacterium Tuberculosis
Structure, Function, and Therapeutic Advances
- 1st Edition - July 1, 2024
- Authors: Ali Akbar Velayati, Parissa Farnia
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 2 1 7 1 2 - 8
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 1 7 1 3 - 5
Pili in Mycobacterium Tuberculosis: Structure, Function, and Therapeutic Advances discusses the types of pili produced by the tuberculosis-causing bacterium, Mycobacte… Read more
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Request a sales quotePili in Mycobacterium Tuberculosis: Structure, Function, and Therapeutic Advances discusses the types of pili produced by the tuberculosis-causing bacterium, Mycobacterium tuberculosis (MTBC). The book examines the structure of pili shown under electron and atomic force microscopy and by using whole genome sequencing, and outlines the importance of pili in mycobacterium tuberculosis. It then explores the role of pili in bacteria-host interactions and in drug development and delivery. Sections open with an overview of the structure, synthesis, and function of pili in bacteria. This includes taxonomy and the role of pili in diseases.
The book also examines the preparation of Mycobacterium tuberculosis for electronic and atomic microscopy and looks at the different life cycles and susceptibility patterns of MTBC and goes on to discuss the expression and function of pili using whole genome sequencing and PCR-based methods and delves into bacteria host interactions. Lastly, it explores the development of new drugs and its delivery by pili.
- Covers the structure, synthesis, and function of pili produced by the tuberculosis-causing bacterium, Mycobacterium tuberculosis (MTBC)
- Explains the mechanism of bacteria-host attachment and the importance of this phenomena in mycobacterium tuberculosis pili and other bacteria
- Emphasizes the use of advanced techniques to study and investigate the TB-bacilli and its interaction with host cells
Researchers in microbiology involved in the study of mycobacteriology and the MTBC bacteria, particularly those interested in researching pili in Mycobacterium tuberculosis Researchers working in antibiotics development, vaccine development, and host-directed therapy
1: The structure and function of pili in bacteria
1.1. Taxonomy of mycobacteria
1.2. Different pili in bacteria genes
1.3. Cell wall and pili in mycobacteria
1.4. The role and function of pili in diseases
2: The structure of pili under electron and atomic force microscopy
2.1 Preparation of Mycobacterium tuberculosis for electron microscopy
2.2 Preparation of Mycobacterium tuberculosis for atomic force microscopy
2.3 Preparation of different life cycle and susceptibility pattern of Mycobacterium tuberculosis
2.4 Differences of pili formation in Mycobacterium tuberculosis and their role in increase surveillance
3: The pili at genomic level
3.1. Whole genome of Mycobacterium Tuberculosis
3.2. Genes related to pili expression and function in Tuberculosis and other mycobacterium species
4: The design for drug delivery using pili in Mycobacterium tuberculosis
4.1 Pili application in drug –delivery in different bacteria
4.2 Pili application in drug –delivery in mycobacteria pili, Mycobacterium tuberculosis, drug delivery system
5: The Role and possible function of pili in Mycobacterium tuberculosis with host
5.1: the role of bacterial pili in host
5.2: the role and possible function of mycobacterium tuberculosis pili in host
1.1. Taxonomy of mycobacteria
1.2. Different pili in bacteria genes
1.3. Cell wall and pili in mycobacteria
1.4. The role and function of pili in diseases
2: The structure of pili under electron and atomic force microscopy
2.1 Preparation of Mycobacterium tuberculosis for electron microscopy
2.2 Preparation of Mycobacterium tuberculosis for atomic force microscopy
2.3 Preparation of different life cycle and susceptibility pattern of Mycobacterium tuberculosis
2.4 Differences of pili formation in Mycobacterium tuberculosis and their role in increase surveillance
3: The pili at genomic level
3.1. Whole genome of Mycobacterium Tuberculosis
3.2. Genes related to pili expression and function in Tuberculosis and other mycobacterium species
4: The design for drug delivery using pili in Mycobacterium tuberculosis
4.1 Pili application in drug –delivery in different bacteria
4.2 Pili application in drug –delivery in mycobacteria pili, Mycobacterium tuberculosis, drug delivery system
5: The Role and possible function of pili in Mycobacterium tuberculosis with host
5.1: the role of bacterial pili in host
5.2: the role and possible function of mycobacterium tuberculosis pili in host
- No. of pages: 300
- Language: English
- Edition: 1
- Published: July 1, 2024
- Imprint: Academic Press
- Paperback ISBN: 9780443217128
AV
Ali Akbar Velayati
Dr. Velayati is the Director of National Research Institute of Tuberculosis and Lung Diseases (NRITLD) at the Shahid
Beheshti University of Medical Sciences. He is a Full Professor of Pediatric Infectious Disease and he has guided more than
300 MD and PhD students. He is the Head of Mycobacteriology Research Center in NRITLD, where he directly monitors
the basic and clinical trial on tuberculosis. Dr. Velayati is President of the Asian African Society of Mycobacteriology
and Chief Editor of the International Journal of Mycobacteriology. He is also the Chief Editor of the Journal of Preventive,
Diagnostic and Treatment Strategies in Medicine and the Biomedical and Biotechnology Research Journal.
Affiliations and expertise
Director, National Research Institute of Tuberculosis and Lung Diseases (NRITLD)PF
Parissa Farnia
Dr. Farnia has special expertise in Mycobacteriology. She has published the majority of her work in the Medicine area (58%) and holds a 1.0 FWCI in that category. She holds an average number of 3.2 citations per publication. She has published multiple times in journals including the International Journal of Clinical and Experimental Biology; the International Journal of Mycrobacteriology; and the International Journal of Tuberculosis and Lung Disease.
Dr. Farina’s publications span international, national and institutional collaboration. 32.7% of her publications are co-authored with researchers in other countries.
Affiliations and expertise
Director, Mycobacteriology Research Center, National Research Institute of Tuberculosis and Lung Disease (NRITLD), Shahid Beheshti University of Medical Science, WHO Collaborating Centre, Masih Daneshvari Hospital, Iran