Phytomedicine

A Treasure of Pharmacologically Active Products from Plants

1st Edition - February 20, 2021
Imprint: Academic Press
Editors: Rouf Ahmad Bhat, Khalid Rehman Hakeem, Moonisa Aslam Dervash
Language: English
Paperback ISBN:
9 7 8 - 0 - 1 2 - 8 2 4 1 0 9 - 7
eBook ISBN:
9 7 8 - 0 - 1 2 - 8 2 4 1 1 0 - 3

Phytomedicine: A Treasure of Pharmacologically Active Products from Plants aims to present updated knowledge of plant-based medicines in terms of their research and developme… Read more

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Phytomedicine: A Treasure of Pharmacologically Active Products from Plants aims to present updated knowledge of plant-based medicines in terms of their research and development, production, and utilization, from the viewpoint of sustainability and by using the latest technologies. The book explores different phytometabolites on a mass scale, coupled with the efficacy, performance and applicability on target organisms to treat curable and fatal diseases.

Readers will find a coherent package of phytotherapeutic information regarding inclusive assortment of research based, scientific amplitude of metabolites from the plant world encompassing various action plans. Information is presented sequentially regarding phytochemistry, biological activity and the serviceable aspects of bioactive compounds. The book also addresses various advancements and achievements of novel drugs from plants using molecular and enzymatic activities, and various technological tools in an ecofriendly fashion.

Cover image
Title page
Table of Contents
Copyright
Contributors
About the editors
Foreword
Preface
About the book
Chapter 1: Phytomedicines: Diversity, extraction, and conservation strategies
Abstract
1: Introduction
2: Prepreparation of plant samples for extraction of phytochemicals
3: Extraction methods for phytochemicals
4: Diversity of phytochemicals
5: Regulation of herbal drugs
6: Global market potential of phytomedicines
7: Causes for increased interest in phytomedicines
8: Conservation strategies for phytomedicines
9: Conclusion
Chapter 2: Biotechnological approaches for conservation of medicinal plants
Abstract
1: Introduction
2: Knowledge about diversity of medicinal plants in the last decade
3: The problems of subtracting medicinal herbs
4: Conservation strategies for medicinal plants
5: Plant tissue culture: A strategy for conservation of medicinal plants
6: Conclusions
Chapter 3: Plant biotechnologies for processing raw products in phytomedicines
Abstract
1: Introduction
2: Impact of GMOs on public health
3: GMOs: Allergy triggers
4: Protocol for risk assessment for food allergies
5: α-Amylase inhibitors
6: Trypsin inhibitors
7: Lectins
8: Proteins related to pathogenesis
9: Modification of plant toxicity
10: Trends in biotechnologies
11: Conclusions and recommendations
Chapter 4: Phytomedicine and phytonanocomposites—An expanding horizon
Abstract
Acknowledgments
1: Introduction
2: Approved or established plant-based drugs
3: Phytonanocomposites
4: Concluding remarks and perspectives
Chapter 5: Herbal medicine: Old practice and modern perspectives
Abstract
1: Introduction
2: Plant active ingredients for treatment
3: Plants as sources of antimicrobial agents
4: Herbal medicine
5: Herbal medicine history
6: Herbal medicine nowadays
7: Preference for herbal drugs in modern societies
8: Phytochemicals: The mechanism of action
9: Prospects of phytochemicals as a repository of antimicrobial and chemotherapeutic representatives
10: Natural products: The future scaffolds for novel antimicrobials
11: Conclusion
Chapter 6: Bioactive compounds obtained from plants, their pharmacological applications and encapsulation
Abstract
1: Introduction
2: Factors that influence the production of bioactive compounds
3: Application of bioactive compounds from plants in medicine
4: Encapsulation of phytochemicals
5: Future perspectives of phytomedicines
6: Conclusions
Chapter 7: Medicinal plants and their traditional uses in different locations
Abstract
1: Introduction
2: Traditional medicine
3: Ethnopharmacology
4: Medicinal plants
5: Herbal medicine
6: Global use of herbal medicine
7: Use of medicinal plants in Mexico: Case study
8: Conclusion and perspectives
Chapter 8: Perspectives of phytotherapeutics: Diagnosis and cure
Abstract
1: Overview of phytotherapeutics
2: Preclinical and clinical research on phytotherapeutics
3: Quality control and standardization of phytotherapeutics
4: Unevenness in phytotherapeutics: Variation in the concentration of biologically active constituents
5: Phytotherapeutics for treating major ailments involving vital organs
6: New drug delivery systems and formulations for phytotherapies
7: Misuse of phytotherapies: Consideration of side effects
8: Recent developments in phytotherapy
9: Conclusion
Chapter 9: Ethnobotanical perspectives in the treatment of communicable and noncommunicable diseases
Abstract
1: Introduction
2: State of disease
3: Ethnobotany perspectives
4: Conclusions
Chapter 10: Health benefits of bioactive compounds from microalgae
Abstract
1: Introduction
2: Microalgae and bioactive compounds production and synthesis
3: Bioactive compounds
4: Role of bioactive compound in health promotion
5: Conclusion
Chapter 11: Some special diets used as neutraceuticals in Unani system of medicine with modern aspects
Abstract
1: Introduction
2: Special diets used in Unani Medicine with modern approach
3: Conclusion and future aspect
Chapter 12: Phytomedicines: Synergistic and antagonistic phytometabolites-drug interactions
Abstract
1: Background
2: Phytometabolite-drug interaction
3: Not recommended combinations of drugs with phytometabolites
4: Citrus paradisi (grapefruit) juice and drugs
5: Conclusions and recommendations
Chapter 13: Role of genetically modified plant repository in biopharmaceutical industries
Abstract
1: Introduction
2: Genetically modified plants
3: Production system for plant-derived biopharmaceuticals
4: Plant expression host
5: Mode of action
6: Future developments of GM plants in biopharmaceuticals
Chapter 14: Role of phytomedicines in metabolic disorders
Abstract
1: Introduction
2: Metabolic disorders: Definition, causes, and prevalence
3: Traditional remedies used for the treatment of MDs
4: In vitro and preclinical studies of the use of herbal medicine in MDs
5: Clinical studies of the use of herbal medicines and natural compounds in MD: Scientific evidence
6: Conclusion
Chapter 15: Artemisia amygdalina Decne.: A rich repository of pharmacologically vital phytoconstituents
Abstract
Acknowledgments
1: Introduction
2: Major therapeutic properties of A. amygdalina
3: Pharmacologically active phytoconstituents isolated from A. amygdalina
4: Conclusions
Chapter 16: Bioprospecting of endophytic fungi for antibacterial and antifungal activities
Abstract
1: Introduction
2: Bioprospecting of endophytic fungi
3: Antibacterial activity
4: Antifungal activity
5: Conclusion
Chapter 17: Bioprospecting appraisal of Himalayan pindrow fir for pharmacological applications
Abstract
1: Introduction
2: Conclusion and future prospects
Chapter 18: Date palm (Phoenix dactylifera L.) secondary metabolites: Bioactivity and pharmaceutical potential
Abstract
1: Introduction
2: Nutritional and health benefits of dates
3: Biotic factors influencing biosynthesis
4: Abiotic factors influencing biosynthesis
5: Pharmaceutical potentialities
6: Metabolomics
7: Conclusion
Chapter 19: The inhibitory role of the metabolites of Moringa oleifera seeds in cancer cells by apoptosis and cell cycle arrest activation
Abstract
1: Introduction
2: Moringa oleifera tree is miraculous
3: Pharmacological activities of the seeds of Moringa oleifera
4: Antioxidant and anticancer activities of the seeds of Moringa oleifera
5: Apoptosis and its pathways
6: Ability of compounds in Moringa oleifera seeds to activate cancer cell apoptosis
7: Fatty acid contents of Moringa oleifera seeds
8: Induction of cell cycle arrest by Moringa oleifera seed bioactive compounds
9: Conclusion
Chapter 20: The medicinal properties of Olax subscorpioidea
Abstract
1: Introduction
2: Distribution, description and traditional uses of Olax subscorpioidea
3: Anticancer properties of Olax subscorpioidea
4: Antimicrobial properties of Olax subscorpioidea
5: Other medicinal properties of Olax subscorpioidea
6: Conclusion
Chapter 21: Phytotherapeutic agents for neurodegenerative disorders: A neuropharmacological review
Abstract
1: Introduction
2: Neurodegenerative diseases and their progression
3: Phytochemicals overview and mechanism of actions
4: Specific neuroprotective phytochemicals and their mode of action on neurodegenerative disorders
5: Nano formulations from active phytochemicals having efficacy in neurodegenerative disorders
6: Conclusion
Chapter 22: Hepatotoxicity: Its physiological pathways and control measures using phyto-polyphenols
Abstract
1: Introduction
2: Liver as main metabolic organ
3: Hepatotoxic effects of some plant extracts/metabolites
4: Detoxification in liver
5: Paracetamol-induced liver injury
6: Attenuation of hepatotoxicity using natural phytochemicals
Chapter 23: Nanosized delivery systems for plant-derived therapeutic compounds and their synthetic derivative for cancer therapy
Abstract
1: Introduction
2: Phytochemicals and their synthetic analogues with anticancer potential
3: Problems encountered in use phytoconstituents as anticancer agents
4: Nanotechnology and phytomedicine
5: Phytoconstituents loaded nanoparticles with anticancer activity
6: Safety and toxicity of the developed nanoparticles
7: Clinical uses
8: Conclusion
Chapter 24: Potential antioxidative response of bioactive products from Ganoderma lucidum and Podophyllum hexandrum
Abstract
1: Introduction
2: Bioactive compounds of Podophyllum hexandrum and Ganoderma lucidum
3: Antioxidative property of Ganoderma lucidum
4: Antioxidative properties of Podophyllum hexandrum
5: Biosynthetic pathway of an antioxidant Podophyllotoxin
6: Biosynthetic pathway of Polysaccharide from Ganoderma lucidum
7: Conclusion
Chapter 25: Phytomedicine and the COVID-19 pandemic
Abstract
1: Introduction
2: The origin of COVID-19 pandemic
3: Pathogenesis of SARS-CoV-2
4: Options for the treatment of Covid-19 infection: Is there room for phytomedicine?
5: Prospective phytomedicines for COVID-19 and their possible mode of action
6: Plant secondary metabolites and antiviral drugs
7: Conclusion
Chapter 26: Phytopharmaceutical marketing: A case study of USPs used for phytomedicine promotion
Abstract
1: Introduction
2: Phytopharmaceutical market global scenario
3: USP: A USP is what makes you different from your competitor
4: Popular USPs in phytomedicine marketing
5: USPs can be misleading
6: Conclusion
Index

Rouf Ahmad Bhat

Dr. Rouf Ahmad Bhat pursued his doctorate at Sher-e-Kashmir University of Agricultural Sciences and Technology Kashmir (Division of Environmental Sciences) and is presently working in the Department of School Education, Government of Jammu and Kashmir. Dr. Bhat has been teaching for the past 09 years and is an author of more than 55 research articles (h-index 32; i-index 52; total citation 4000) and 50 chapters and has published more than 50 books with international publishers. Besides, he has worked as an associate environmental expert in World Bank-funded Flood Recovery Project and the environmental support staff in the Asian Development Bank (ADB) funded development projects.

Affiliations and expertise

Renowned Researcher and Instructor in Environmental Sciences, Department of School Education, Jammu and Kashmir, India

Khalid Rehman Hakeem

Dr. Khalid Rehman Hakeem (PhD) is Professor at King Abdulaziz University, Jeddah, Saudi Arabia. He has more both teaching and research experience in plant eco-physiology, biotechnology and molecular biology, medicinal plant research, plant-microbe-soil interactions as well as in environmental studies. He has served as the visiting scientist at Jinan University, Guangzhou, China. He has more than 110 research publications in peer-reviewed international journals has extensive book publishing experience as well. He is included in the advisory board of Cambridge Scholars Publishing, UK. He is a fellow of Plantae group of the American Society of Plant Biologists, member of the World Academy of Sciences, member of the International Society for Development and Sustainability, Japan, and member of Asian Federation of Biotechnology, Korea.

Affiliations and expertise

Professor, Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah, Makkah Province Kingdom of Saudi Arabia

Moonisa Aslam Dervash

Moonisa Aslam Dervash is an assistant professor at Cluster University Srinagar, with specializations in mesofauna, phyto-chemistry, and carbon sequestration. She is the author of numerous research articles and has published several books with international publishers.

Affiliations and expertise

Assistant Professor, Department of Environmental Science, Cluster University Srinagar, Srinagar, India

Life Sciences

Physical Sciences & Engineering

Social Sciences & Humanities

Health

Phytomedicine

A Treasure of Pharmacologically Active Products from Plants

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Rouf Ahmad Bhat

Khalid Rehman Hakeem

Moonisa Aslam Dervash

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