Phytochemical Nanodelivery Systems as Potential Biopharmaceuticals
- 1st Edition - January 13, 2023
- Editors: J. Basilio Heredia, Erick P. Gutierrez-Grijalva, Angel Licea-Claverie, Janet Alejandra Gutierrez-Uribe, Jayanta Kumar Patra
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 9 0 3 9 0 - 5
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 0 4 1 5 - 5
Phytochemical Nanodelivery Systems as Potential Biopharmaceuticals comprehensively reviews current information on nanotechnology applied to phytochemical nanoencap… Read more
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Request a sales quotePhytochemical Nanodelivery Systems as Potential Biopharmaceuticals comprehensively reviews current information on nanotechnology applied to phytochemical nanoencapsulation to enhance their bioavailability and bioactivity.
The book is divided into two sections, the first section critically reviews current information on the field of nanotechnology and phytochemicals, and the second section highlights the pre-clinical and clinical studies of phytochemicals to comprehensively review the efficacy of these molecules as drugs of human use.
Phytochemical Nanodelivery Systems as Potential Biopharmaceuticals provides a useful overview of this rapidly evolving field for materials scientists and pharmaceutical scientists, as well as for those with an interest in biopharmaceuticals from plant sources, such as organic chemists and food scientists.
- Provides an introduction to both phytochemicals and nanomaterials for use in biopharmaceutics, allowing both materials scientists and pharmaceutical scientists to gain a basic understanding of each field
- Reviews key phytochemical types for use as biopharmaceuticals, including terpenes, alkaloids, glucosinolates and more
- Explores the various nanomaterials and nanoencapsulation techniques for administration of phytochemical nanoformulations
Materials scientists, pharmaceutical scientists. Organic chemists and food scientists with an interest in biopharmaceuticals from plant sources
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Preface
- Section 1: Nanomaterials applied to phytochemicals
- Chapter 1: Phytochemicals as potential biopharmaceutical agents
- Abstract
- 1.1: Terpenes
- 1.2: Alkaloids
- 1.3: Phenolic compounds
- 1.4: Glucosinolates
- 1.5: Preclinical studies
- 1.6: Clinical studies
- 1.7: Conclusions
- References
- Chapter 2: Diseases with the highest mortality
- Abstract
- 2.1: Introduction
- 2.2: Epidemic transition and increasing trends of noncommunicable diseases
- 2.3: Common risk factors
- 2.4: Conclusions and perspectives
- References
- Chapter 3: Nanomaterials
- Abstract
- 3.1: Introduction
- 3.2: Classification and morphology
- 3.3: Synthetic and natural polymer nanostructures
- 3.4: Synthesis of nanostructures by polymerization and copolymerization
- 3.5: Synthesis of nanostructures by polymer modification
- 3.6: Preparation of nanostructures by self-assembly
- 3.7: Concluding remarks
- References
- Chapter 4: Methods of nanoencapsulation of phytochemicals using organic platforms
- Abstract
- 4.1: Introduction
- 4.2: Nanoencapsulation in liposomes
- 4.3: Nanoencapsulation in micelles
- 4.4: Nanoencapsulation in polyelectrolyte complexes
- 4.5: Nanoencapsulation in nanogels
- 4.6: Nanoencapsulation in dendrimers
- 4.7: Determination of encapsulation efficiency, drug loading, and stability
- 4.8: Concluding remarks
- References
- Chapter 5: Administration of phytochemical nanoformulations (main routes of drug delivery)
- Abstract
- 5.1: Introduction
- 5.2: Oral drug delivery
- 5.3: Intravenous drug delivery
- 5.4: Inhalational/pulmonary drug delivery system
- 5.5: Transdermal drug delivery system
- 5.6: Less conventional modes of drug delivery
- 5.7: Nanodelivery systems
- 5.8: Phytochemicals
- 5.9: Conclusion
- References
- Section 2: Phytochemicals and nanotechnology
- Chapter 6: Nanoformulations applied to the delivery of terpenes
- Abstract
- 6.1: Introduction
- 6.2: Terpenes nanodelivery systems
- 6.3: Administration routes of terpenes nanodelivery systems
- 6.4: Role of terpenes in the formulations
- 6.5: Potential terpene nanodelivery systems in prevention and treatment of diseases
- 6.6: Conclusions
- References
- Chapter 7: Nanoformulations applied to the delivery of alkaloids
- Abstract
- 7.1: Introduction
- 7.2: Alkaloids
- 7.3: Alkaloid’s delivery systems: In vitro studies
- 7.4: Alkaloid delivery systems: In vivo studies
- 7.5: Conclusions
- References
- Chapter 8: Nanoformulations applied to the delivery of phenolic compound
- Abstract
- 8.1: Introduction
- 8.2: Nanotechnology as an efficient strategy for delivery of polyphenols
- References
- Chapter 9: Nanoformulations applied to the delivery of sulforaphane
- Abstract
- 9.1: Introduction
- 9.2: Biological activity of glucosinolates and their hydrolysis products, isothyocianates
- 9.3: Nanoformulations for the delivery of sulforaphane
- 9.4: Conclusions
- References
- Chapter 10: Perspectives
- Abstract
- References
- Index
- No. of pages: 366
- Language: English
- Edition: 1
- Published: January 13, 2023
- Imprint: Elsevier
- Paperback ISBN: 9780323903905
- eBook ISBN: 9780323904155
JH
J. Basilio Heredia
Dr J. Basilio Heredia is a Research Professor at the Research Center for Food and Development, (CONACYT) Mexico.
He completed his PhD in Food Science and Technology at Texas A&M University, USA (2006). His research focuses on phytochemicals, nutraceuticals, antioxidants and bioactive compounds for biomedical applications.
Affiliations and expertise
Research Professor, Research Center for Food and Development, (CONACYT), MexicoEG
Erick P. Gutierrez-Grijalva
Dr Gutiérrez-Grijalva has a degree in Biochemical Engineering, and a Doctorate in Sciences, with specialization in the study of metabolomics, bioavailability and bioactivity of phytochemicals from medicinal plants from CIAD. His research is focuses on the metabolomics, bioactivity and bioavailability of phytochemicals, with specialism in the phytochemicals from plants of the Northwestern region of Mexico.
Affiliations and expertise
Research Center for Food and Development, CONACYT (Consejo Nacional de Ciencia y Tecnología), Sinaloa, MexicoAL
Angel Licea-Claverie
Dr Angel Licea-Claveríe is a full-time Professor at the Instituto Tecnológico de Tijuana, which is part of the Tecnológico Nacional de México (Mexico). He completed his PhD on Polymer Chemistry at the Leuna-Merseburg Technological University in Germany (1990). He has 20 years of experience in the study of temperature and pH sensitive polymers and 14 years of experience on controlled radical polymerization techniques. His research group have studied the controlled release of anti-inflammatory and anticancer drugs from the sensitive polymeric materials developed. Currently he works on the development of nanocarriers and hydrogel-based nanocomposite biomaterials. He is a member of the Mexican Polymer Society since 1998 and was its National President (2016-2017), he is also a Member of the Mexican Chemical Society since 1994, and Member of the American Chemical Society, Division of Polymer Chemistry, since 2006.
Affiliations and expertise
Full-time Professor, Instituto Tecnológico de Tijuana, Tecnologico Nacional de Mexico, MexicoJG
Janet Alejandra Gutierrez-Uribe
Dr. Janet Gutiérrez is an Associate Professor in the NutriOmics research group at the School of Engineering and Sciences from Tecnológico de Monterrey, and Director of the Department of Bioengineering and Science from the South Region of Tecnológico de Monterrey. For over 15 years, she has been working on the phytochemistry and nutritional biochemistry of phenolic compounds and other nutraceuticals. She has published more than 90 papers in different prestigious journals and is the inventor of more than 10 patents and applications in Mexico and abroad. Working with industry and social services are her main drivers in the development of challenges related to biochemistry, molecular biology, cell culture and nutraceutical discovery and characterization. In 2017, the State of Nuevo Leon awarded her with the medal for the Civic Merit due to her research career.
She is a member of the National Researchers Council; the technical committee of the National Network for Research on functional foods and nutraceuticals (AlfaNutra) and participant in CYTED Network for Foods with Probiotic functionality for malnourished childen (PROINFANT). Additionally, since 2018, she is a part of the Young Scientists selected by the World Economic Forum.
Affiliations and expertise
Associate professor, Tecnologico de Monterrey, School of Engineering and Sciences; Healthy Foods Unit Leader, The Institute for Obesity Research, Tecnologico de Monterrey, MexicoJP
Jayanta Kumar Patra
Prof. Dr. Jayanta Kumar Patra, M.Sc., Ph.D., P.D.F, is currently working as an Associate Professor
at Dongguk University, Republic of Korea. He holds about 14 years of research and teaching experience in the fields of food, pharmacology, and nano-biotechnology. To his credit, he has published more than 200 papers in various national and international peer-reviewed journals and around 50 book chapters
in different edited books. Dr. Patra has also authored 22 books in various academic publications.
Affiliations and expertise
Associate Professor, Research Institute of Integrative Life Sciences, Dongguk University, South KoreaRead Phytochemical Nanodelivery Systems as Potential Biopharmaceuticals on ScienceDirect