Pharmacology for Dentistry 5th ed
- 5th Edition - April 3, 2025
- Imprint: Elsevier India
- Authors: Tara V. Shanbhag, Smita Shenoy
- Language: English
- Paperback ISBN:9 7 8 - 8 1 - 3 1 2 - 7 0 9 2 - 9
- eBook ISBN:9 7 8 - 8 1 - 3 1 2 - 7 0 9 3 - 6
The fifth edition of Pharmacology for Dentistry is completely updated in accordance with the syllabus prescribed by Dental Council of India. It is designed to meet the requirement… Read more
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Request a sales quoteThe fifth edition of Pharmacology for Dentistry is completely updated in accordance with the syllabus prescribed by Dental Council of India. It is designed to meet the requirement of students pursuing undergraduate courses in dentistry and for practicing dentists.
New to This Edition
• Significant content enhancement and reorganization to ensure relevance and renewed focus on applicationbased learning.
• Treatment guidelines have been updated to ensure evidence-based clinical practice and quality of care.
• Key points highlight summary for dentists at end of topics wherever relevant, stimulates enthusiasm for subject.
• Mechanism of action of drugs are illustrated with diagrams whenever appropriate.
Salient Features
• Thorough update of content, figures, flowcharts, and tables with addition of specific description of drugs makes learning and comprehension easier for students.
• Textual presentation in simple, precise and point-wise manner, makes it easy to read and interpret the information.
• Some topics have been simplified for better understanding of the subject.
• Student-friendly mnemonics, line diagrams and flowcharts help students to revise the subject before examination.
Online Resources at www.medenact.com
• Complimentary access to full e-book
• 11 Animations on various topics, help learners understand concepts more deeply or practice for exams.
• Significant content enhancement and reorganization to ensure relevance and renewed focus on applicationbased learning.
• Treatment guidelines have been updated to ensure evidence-based clinical practice and quality of care.
• Key points highlight summary for dentists at end of topics wherever relevant, stimulates enthusiasm for subject.
• Mechanism of action of drugs are illustrated with diagrams whenever appropriate.
Salient Features
• Thorough update of content, figures, flowcharts, and tables with addition of specific description of drugs makes learning and comprehension easier for students.
• Textual presentation in simple, precise and point-wise manner, makes it easy to read and interpret the information.
• Some topics have been simplified for better understanding of the subject.
• Student-friendly mnemonics, line diagrams and flowcharts help students to revise the subject before examination.
Online Resources at www.medenact.com
• Complimentary access to full e-book
• 11 Animations on various topics, help learners understand concepts more deeply or practice for exams.
- Pharmacology for Dentistry
- Cover image
- Title page
- Table of Contents
- Copyright
- Foreword to the first edition
- Preface to the fifth edition
- Preface to the first edition
- Brief contents
- List of Illustrations
- List of Tables
- 1. General pharmacology
- Definitions
- Sources of drug information
- Drug nomenclature
- Sources of drugs
- Routes of drug administration
- Local routes
- Systemic routes
- Special drug-delivery systems
- Pharmacokinetics
- Drug absorption and bioavailability
- Drug distribution
- Biotransformation (drug metabolism)
- Drug excretion
- Pharmacokinetic parameters
- Pharmacodynamics
- Types of drug action
- Mechanism of drug action
- Dose–response relationship
- Combined effect of drugs
- Factors modifying drug action
- Drug factors
- Patient factors
- Drug interactions
- Pharmaceutical interactions
- Pharmacokinetic interactions
- Pharmacodynamic interactions
- Adverse drug effects
- Types of adverse drug reactions
- Adverse drug effects
- Pharmacovigilance
- Treatment of poisoning
- General management
- Specific management
- 2. Drug dosage forms
- Solid dosage forms
- Semisolid dosage forms
- Liquid dosage forms
- Gaseous and volatile liquid dosage forms
- Injectable dosage forms
- New drug-delivery systems
- 3. Autonomic pharmacology
- Introduction to autonomic pharmacology
- Cholinergic system
- Cholinergic transmission
- Cholinergic agents (cholinomimetics, parasympathomimetics)
- Classification
- Anticholinergic agents (cholinergic receptor blockers)
- Antimuscarinic agents (muscarinic receptor antagonists)
- Ganglionic blockers
- Skeletal muscle relaxants
- Classification
- Adrenergic agonists (sympathomimetic agents)
- Adrenergic transmission
- Metabolism of catecholamines
- Types, distribution and functions of adrenergic receptors
- Adrenergic drugs (sympathomimetics)
- Direct acting sympathomimetics
- Indirect acting sympathomimetics
- Mixed acting sympathomimetics
- Adrenergic receptor blockers
- Alpha-adrenergic blockers
- Classification
- Beta-adrenergic blockers
- Classification
- Drug interactions
- Therapeutic uses of β-blockers
- Selective β1-adrenergic blockers (second generation)
- β-blockers with additional vasodilatory action (third generation)
- 4. Renal pharmacology
- Mechanism of urine formation
- Diuretics
- Classification of diuretics according to primary site of action in the nephron (Fig. 4.1)
- 5. Drugs affecting cardiovascular function
- Antihypertensive drugs
- Blood pressure
- Classification of antihypertensive drugs (Fig. 5.1)
- Treatment of hypertension
- Drugs to be avoided in specific conditions
- Hypertensive urgency and emergency
- Antianginal drugs
- Drugs used in congestive cardiac failure
- Diuretics
- Vasodilators
- β-blockers
- Cardiac glycosides
- Sympathomimetic amines
- Phosphodiesterase 3 inhibitors
- Plasma expanders
- Colloidal solutions
- Crystalloids
- Uses of plasma expanders
- Contraindications
- Drugs used in shock
- 6. Drugs acting on central nervous system
- Neurotransmitters and central nervous system
- Neurotransmitters in the central nervous system
- Sedatives and hypnotics
- Classification of sedatives and hypnotics
- Benzodiazepines
- Inverse agonist (β-carboline)
- Benzodiazepine antagonist (flumazenil)
- Barbiturates
- Nonbenzodiazepine hypnotics
- General anaesthetics
- Classification
- Inhalational anaesthetics
- Parenteral general anaesthetics
- Preanaesthetic medication
- Conscious sedation
- Local anaesthetics
- Chemistry
- Some important local anaesthetics (Table 6.7)
- Techniques of local anaesthesia (Table 6.8)
- Drug interactions
- Alcohol (ethanol)
- Acute ethanol overdosage (acute alcohol intoxication)
- Withdrawal syndrome
- Chronic alcoholism
- Antiepileptic drugs
- Phenytoin (diphenylhydantoin)
- Fosphenytoin
- Carbamazepine (iminostilbene)
- Oxcarbazepine (iminostilbene)
- Phenobarbitone (barbiturate)
- Ethosuximide (succinimide)
- Valproic acid (sodium valproate): Carboxylic acid derivative
- Diazepam, lorazepam, clonazepam bzds
- Newer antiepileptics
- Status epilepticus
- Analgesics
- Opioid analgesics
- Opioid agonists
- Therapeutic uses of opioids
- Opioid antagonists: Naloxone, naltrexone and nalmefene (see Fig. 6.9)
- Psychopharmacology
- Antipsychotic drugs
- Antianxiety agents
- Antidepressants
- Tricyclic antidepressants (TCAs)
- Monoamine oxidase inhibitors
- Uses of antidepressants
- Drugs for bipolar disorder
- Lithium carbonate
- 7. Autacoids and respiratory system
- Histamine and antihistamines
- Histamine
- H1-receptor antagonists (H1-blockers, antihistamines)
- Prostaglandins and leukotrienes (eicosanoids)
- Prostaglandins
- Leukotrienes
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Classification
- Mechanism of action
- Pharmacological actions of aspirin and other nsaids
- Pharmacokinetics
- Dosage regimen for aspirin
- Adverse effects
- Salicylism
- Other NSAIDs (Table 7.4)
- Selective COX-2 inhibitors (coxibs)
- Clinical uses of nsaids (for basis and explanation, see ‘pharmacological actions’)
- Drug interactions
- Topical NSAIDs
- Respiratory system
- Drugs used in treatment of cough
- Drugs used in the treatment of bronchial asthma
- Classification of antiasthmatic drugs*
- Inhalational devices
- Treatment of acute severe asthma (status asthmaticus)**
- 8. Gastrointestinal pharmacology
- Emetics and antiemetics
- Mechanism of vomiting
- Emetics
- Antiemetics
- Classification
- Antidiarrhoeal agents
- Management of diarrhoea
- Laxatives (purgatives, cathartics)
- Classification (according to mechanism of action)
- Uses of laxatives with preferred preparations
- Pharmacotherapy of peptic ulcer and gastroesophageal reflux disease
- Physiology of gastric secretion
- Regulation of gastric acid secretion
- Classification of drugs used in peptic ulcer (Fig. 8.4)
- Drugs that inhibit gastric acid secretion
- Ulcer protectives
- Drugs that neutralize gastric acid (antacids)
- Antifoaming agents
- Anti–H. pylori agents
- Drugs useful in gastroesophageal reflux disease
- 9. Drugs affecting coagulation and blood formation
- Drugs affecting coagulation and bleeding
- Haemostatic agents
- Anticoagulants
- Fibrinolytics (thrombolytics)
- Antifibrinolytics
- Antiplatelet drugs
- Classification
- Uses of antiplatelet agents
- Haematinics
- Iron
- 10. Endocrine pharmacology
- Introduction
- Hypothalamic and pituitary hormones
- Thyroid hormones and antithyroid drugs
- Thyroid hormones
- Antithyroid drugs (Fig. 10.3)
- Anabolic steroids
- Corticosteroids
- Adverse reactions
- Therapeutic uses of glucocorticoids
- Relative contraindications for the use of corticosteroids
- Insulin and other antidiabetic agents
- Insulin
- Oral antidiabetic drugs (Table 10.5)
- Agents affecting calcium balance
- Calcium
- Parathyroid hormone
- Vitamin D
- Bisphosphonates
- Mechanism of action
- Pharmacokinetics
- Uses
- Adverse effects
- 11. Chemotherapy
- General considerations
- Classification of antimicrobial agents
- Resistance to antimicrobial agents
- Superinfection (suprainfection)
- Chemoprophylaxis
- Combination of antimicrobial agents
- List of microorganisms
- Selection of an appropriate antimicrobial agent (Fig. 11.3)
- Sulfonamides
- Cotrimoxazole
- Quinolones and fluoroquinolones
- β-Lactam antibiotics
- Penicillins
- β-Lactamase inhibitors
- Cephalosporins
- Carbapenems
- Monobactams
- Aminoglycosides
- Streptomycin
- Gentamicin
- Neomycin and framycetin
- Amikacin and netilmicin
- Tobramycin
- Broad-spectrum antibiotics
- Tetracyclines
- Chloramphenicol
- Macrolides
- Antipseudomonal agents (drugs used in pseudomonal infections)
- Drugs used in anaerobic infections
- Miscellaneous antibacterial agents
- Antitubercular drugs
- Drugs for treatment of tuberculosis
- Other antitubercular agents
- Treatment of tuberculosis
- Drug-sensitive tuberculosis
- Drug-resistant tuberculosis (DR-TB)
- Chemoprophylaxis of tuberculosis
- Role of glucocorticoids in tuberculosis
- Antileprotic drugs
- Dapsone or diamino-diphenyl sulfone
- Rifampin
- Clofazimine
- Chemotherapy of leprosy
- Lepra reaction
- Antifungal agents
- Polyene antibiotics
- Echinocandins
- Flucytosine
- Azoles
- Allylamine
- Other topical agents
- Antiviral agents
- Classification
- Antiherpes agents
- Other antiherpes agents
- Anti-influenza agents
- Antihepatitis drugs
- Antiretroviral agents
- Antimalarial drugs
- 4-aminoquinoline
- Quinoline methanol
- Artemisinin and its derivatives (qinghaosu compounds)
- Nitroimidazoles
- Metronidazole
- Tinidazole
- Secnidazole
- Ornidazole and satranidazole
- Anthelmintic drugs
- Mebendazole
- Albendazole
- Levamisole
- Pyrantel pamoate
- Diethylcarbamazine (DEC)
- Ivermectin
- Praziquantel
- Niclosamide
- Anticancer drugs
- Classification of anticancer drugs
- Toxicity of anticancer drugs (cytotoxic drugs)
- Antimetabolites
- Plant products
- Anticancer antibiotics
- Enzyme
- Hormonal agents
- 12. Dental pharmacology
- Fluorides
- Actions on teeth
- Fluorides in dentistry
- Topical fluorides
- Fluoride toxicity
- Astringents
- Types of astringents
- Uses of astringents
- Desensitizing agents
- Uses
- Anticaries agents
- Fluorides
- Nonfluoride agents
- Prevention of caries
- Antiplaque and antigingivitis agents
- Fluorides
- Enzymes
- Metal ions
- Triclosan
- Chlorhexidine
- Essential oils
- Quaternary ammonium compounds
- Others
- Dentifrices
- Active ingredients
- Inactive ingredients
- Uses of dentifrices
- Adverse effects of toothpaste
- Disclosing agents
- Bleaching agents
- Adverse effects
- Nonbleaching whiteners
- Obtundents
- Mechanism of action
- Commonly used obtundents
- Uses
- Disadvantage
- Mummifying agents
- Mouthwashes (mouthrinses)
- Uses of mouthwash
- Side effects
- Sialagogues
- Antisialagogues
- 13. Miscellaneous drugs
- Chelating agents
- Dimercaprol
- Disodium edetate
- Calcium disodium edetate
- Desferrioxamine (deferoxamine)
- Deferiprone
- d-Penicillamine
- Antiseptics and disinfectants
- Phenol and related agents
- Alcohols
- Aldehydes
- Oxidizing agents
- Halogens
- Acids
- Metallic salts
- Dyes
- Cationic surfactants
- Vitamins
- Drug treatment of medical emergencies
- Dental tray (emergency drug kit) for dentists
- Appendix
- Index
- Edition: 5
- Published: April 3, 2025
- Imprint: Elsevier India
- Language: English
- Paperback ISBN: 9788131270929
- eBook ISBN: 9788131270936
TS
Tara V. Shanbhag
Tara V Shanbhag is presently Professor and Head, Department of Pharmacology, Srinivas Institute of Medical Sciences and Research Centre, Mukka, Mangalore, India. She has extensive experience in teaching pharmacology to undergraduate students of medical, dental, nursing and allied health sciences. She is an honourable recipient of the ‘Good Teacher’ award. She has also authored books on Pharmacology for Dentistry and Pharmacology for Nurses. She has to her credit several articles in various national and international journals. She has been an examiner to various colleges and universities.
Affiliations and expertise
TARA V SHANBHAG MD
Professor and Head, Department of Pharmacology
Srinivas Institute of Medical Sciences and Research Centre
Mukka, Surathkal, Mangalore
Karnataka, India
Formerly, Professor, Department of Pharmacology
Kasturba Medical College, Manipal, Manipal Academy of Higher Education
Manipal, Karnataka, IndiaSS
Smita Shenoy
Smita Shenoy is presently Additional Professor, Department of Pharmacology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India. She has 15 years of teaching experience and has been an examiner to various colleges and universities. She has been honoured with the ‘Good Teacher’ award. She is a PhD guide. She has authored books on pharmacology and has published several articles in national
Affiliations and expertise
SMITA SHENOY MD
Additional Professor, Department of Pharmacology
Kasturba Medical College, Manipal, Manipal Academy of Higher Education
Manipal, Karnataka, India