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Personal Care Products and Human Health

1st Edition - August 1, 2023

Editor: Philippa D. Darbre

Paperback ISBN:

9 7 8 - 0 - 3 2 3 - 9 9 6 8 4 - 6

eBook ISBN:

9 7 8 - 0 - 3 2 3 - 9 9 6 8 5 - 3

Personal Care Products and Human Health provides background, historical context and the latest research results on personal care products (PCPs) and their impact on human health… Read more

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Personal Care Products and Human Health provides background, historical context and the latest research results on personal care products (PCPs) and their impact on human health and the environment. Sections provide an overview of the functions and mechanisms of action of components of personal care products, discuss environmental toxicology, outline the problems of contamination of water systems from increasing use of personal care products and the resulting toxicities to aquatic wildlife, and offer chapters written by specialists on different aspects of concern for the effects of excessive personal care product usage on human health.

This is a comprehensive reference for toxicologists, environment scientists and those interested in learning about the science behind personal care products and current concerns for environmental and human health.

Cover image
Title page
Table of Contents
Copyright
Contributors
Preface
Section 1. Introduction to the constituents of PCPs and their functions
Chapter 1. Introduction to personal care products
1.1. Introduction
1.2. Historical background
1.3. Sites of exposure of the human body to personal care products
1.4. Functional components of personal care products
1.5. Cosmeceuticals
1.6. Age- and gender-targeted products
1.7. Product format and packaging
1.8. Benefits, adverse effects, and arising concerns
1.9. Concluding comments
Chapter 2. Overview of constituent compounds with concerns for adverse effects on human health
2.1. Introduction
2.2. Widely used constituent chemicals with arising human health concerns
2.3. Nanomaterials
2.4. Natural versus synthetic compounds
2.5. Long-term low-dose mixtures
2.6. Early life exposures
2.7. Concluding comments
Chapter 3. Nanomaterials
3.1. Introduction
3.2. Inorganic nanoparticles in sunscreens
3.3. Use of gold and silver nanoparticles
3.4. Other inorganic nanoparticles
3.5. Organic nanoparticles
3.6. Concluding comments
Chapter 4. Cosmeceuticals
4.1. Introduction
4.2. Antiaging cosmeceuticals
4.3. Skin whitening and depigmentation
4.4. Hair care cosmeceuticals
4.5. Wound healing and antiinflammatory cosmeceuticals
4.6. Antimicrobial and personal pest control cosmeceuticals
4.7. Disorder-related cosmeceuticals
4.8. Aromatherapy
4.9. Concluding comments
Chapter 5. Plant-based ingredients in personal care products
5.1. Introduction
5.2. Essential oils
5.3. Phytoestrogens
5.4. Plant-based colorants
5.5. Plant-based sun protection
5.6. Plant-based oils, fats, and waxes
5.7. Plant-based preservatives
5.8. Plant-based detergents
5.9. Plant-based wound healing
5.10. Plant-based skin lightening
5.11. Plant cell culture for sustainable production of plant extracts
5.12. Concluding comments
Section 2. Environmental monitoring and human exposure
Chapter 6. Water pollution by personal care products
6.1. Introduction
6.2. Occurrence of PCP in water bodies
6.3. Main classes of compounds and materials contained in personal care products
6.4. Sustainable cosmetics production
Chapter 7. Human exposure and uptake into human tissues
7.1. Introduction
7.2. Parabens
7.3. Triclosan and triclocarban
7.4. UV filters
7.5. Synthetic musks
7.6. Phthalates
7.7. Aluminium
7.8. Cyclic volatile methylsiloxanes
7.9. Concluding comments
Section 3. Human health concerns
Chapter 8. Contact dermatitis
8.1. Introduction
8.2. Global burden and increasing prevalence of PCP-related contact dermatitis
8.3. Anatomical sites of PCP-related contact dermatitis
8.4. Causative PCP components
8.5. Concluding comments
Chapter 9. Respiratory irritation and sensitization
9.1. Introduction
9.2. The respiratory tract as a target for inhaled ingredients of personal care products
9.3. Components of personal care products as pollutants of indoor air
9.4. Occupational asthma in beauty salon workers
9.5. Fragrance and asthma
9.6. Talcum powder
9.7. Nanoparticles
9.8. Early life exposures and adult lung function
9.9. Concluding comments
Chapter 10. Endocrine disruption
10.1. Introduction: What are endocrine-disrupting chemicals and where are they found in personal care products?
10.2. Evidence that endocrine-disrupting chemicals are absorbed from dermal application of personal care products
10.3. Evidence that chemical constituents of personal care products possess endocrine-disrupting properties
10.4. Evidence that endocrine-disrupting chemicals contained in personal care products can affect human health
10.5. Concluding comments
Chapter 11. Early life exposure and developmental consequences
11.1. Introduction
11.2. Evidence for placental transfer of chemicals in personal care products
11.3. Evidence for transfer of chemicals in personal care products during breast feeding
11.4. Early life exposures and disruption of endocrine-regulated developmental pathways
11.5. Early life exposures and susceptibility to dermatitis
11.6. Early life exposures and susceptibility to respiratory disease
11.7. Early life exposures and susceptibility to cancer development
11.8. Concluding comments
Chapter 12. Development of cancer
12.1. Introduction
12.2. Chemical ingredients in personal care products and the hallmarks of cancer
12.3. Individual susceptibility and lifestyle choices
12.4. Lifestyle choices and the tumor microenvironment
12.5. Personal care products and breast cancer
12.6. Personal care products and cancers in other endocrine-sensitive tissues
12.7. Personal care products and endocrine therapy of cancer
12.8. Talcum powder and ovarian cancer
12.9. Sun care products and skin cancer
12.10. Concluding comments
Chapter 13. Aluminum and its carcinogenic traits
13.1. Introduction
13.2. Carcinogens and carcinogenic metals
13.3. Aluminum
13.4. Conclusions
Section 4. Regulatory considerations
Chapter 14. Regulatory considerations and public education
14.1. Introduction
14.2. How is regulation brought about in different countries?
14.3. Challenges for risk assessment of personal care products
14.4. Role of nongovernmental organizations and the mass media
14.5. Use of the precautionary principle
14.6. Need for public education
14.7. Concluding comments
Index