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Peritoneal Tumor Microenvironment of Cancers on Cancer Hallmarks

Perspectives of Translational Medicine

  • 1st Edition - June 27, 2024
  • Latest edition
  • Editors: Yong Sang Song, Danny N. Dhanasekaran, Benjamin K. Tsang, Johji Inazawa, Massoud Mirshahi, Marc Pocard, Ciro Isidoro
  • Language: English

Peritoneal Tumor Microenvironment of Cancers on Cancer Hallmarks: Perspectives of Translational Medicine provides readers with cutting-edge knowledge on tumor microe… Read more

Description

Peritoneal Tumor Microenvironment of Cancers on Cancer Hallmarks: Perspectives of Translational Medicine provides readers with cutting-edge knowledge on tumor microenvironment. By exploring multiple aspects on tumor microenvironment, it gives an integrative insight on cancer diseases ranging from diagnosis to prediction of prognosis and individualized treatment. The book discusses topics such as clinical significance of tumor microenvironment, tumorigenesis and cancer progression, histopathological features of cancer in peritoneum, immune cells in tumor, exosomal cell-to-cell interactions, and therapeutic approaches to target tumor microenvironment. In addition, it discusses tumor evolution during chemotherapy and metastasis and future perspectives on identification and validation of biomarkers using liquid biopsy. This book is a valuable resource for cancer researchers, oncologists, medical doctors, and several members of biomedical field who want to understand the complex microenvironment of peritoneal tumors.

Key features

  • Discusses how to apply tumor microenvironment knowledge to diagnosis, prediction of prognosis, and individualized treatment of cancer
  • Provides readers with up-to-date knowledge on translational medicine, focusing on bench-to-bedside approach for cancer treatment and diagnosis
  • Presents collaborative research works from the perspectives of medical doctors, cancer researchers, basic biological scientists, and bioinformaticians to provide integrative insights on tumor microenvironment

Readership

Cancer researchers, oncologists, medical scientists, clinicians, graduate students

Table of contents

1. What is the tumor microenvironment?

2. Clinical significance of peritoneal cancers

3. Tumor microenvironment of peritoneal carcinomatosis: the concept of premetastatic niche altered before tumor implantation

4. Cellular models for peritoneal cancer research

5. Metabolism of cancer cells altered in peritoneal tumor microenvironment

6. Cell-to-cell interactions in peritoneal tumor microenvironment

7. Diagnostic, prognostic, and therapeutic biomarkers of ovarian cancer

8. Current and future perspectives of xenograft models of human ovarian cancer

9. Tumor microenvironment and chemoresistance

10. Tumor microenvironment and metastatic progression of cancer

11. Role of microbiome and microbial extracellular vesicles in tumor microenvironment

12. Tumor evolution during chemotherapy

13. Tumor evolution during metastasis

14. Future perspective: identification and validation of biomarkers using liquid biopsy

Product details

  • Edition: 1
  • Latest edition
  • Published: June 27, 2024
  • Language: English

About the editors

YS

Yong Sang Song

Yong Sang Song, MD, PhD is currently Professor at Seoul National University, College of Medicine. He received his MD and PhD at the Seoul National University (1983 and 1994 respectively). He was elected as the chairperson of Korean Society of Urogynecology in 2006. He was selected as the Director of Cancer Research Institute at Seoul National University in 2009, and as the President of Korean Society of Cancer Prevention in 2012. He served as the President of International Society of Precision Cancer Medicine (ISPCM) in 2018. His major research interests are molecular mechanisms of tumors, especially the role of tumor microenvironment in cancer cell metabolism, chemoresistance and precision medicine in gynecologic cancer. He is particularly interested in the impact of components of tumor microenvironment in ovarian cancer progression.
Affiliations and expertise
Professor, Seoul National University, College of Medicine, Seoul, South Korea

DD

Danny N. Dhanasekaran

Danny N. Dhanasekaran, PhD, is Samuel Roberts Noble Foundation Endowed Chair in Cancer Research. He is Deputy Director for Basic Sciences and Director, SCC-COBRE & Center for Basic Cancer Research, Stephenson Cancer Center, University of Oklahoma Health Science Center, USA. Danny N. Dhanasekaran, PhD, is Samuel Roberts Noble Foundation Endowed Chair in Cancer Research. He is Deputy Director for Basic Sciences and Director, SCC-COBRE & Center for Basic Cancer Research, Stephenson Cancer Center, University of Oklahoma Health Science Center, USA.
Affiliations and expertise
Samuel Roberts Noble Foundation Endowed Chair in Cancer Research, Deputy Director for Basic Sciences, Director, SCC-COBRE & Center for Basic Cancer Research, Stephenson Cancer Center, University of Oklahoma Health Science Center, USA

BT

Benjamin K. Tsang

Benjamin K Tsang, PhD, is director of Reproductive Biology Unit, professor of Obstetrics & Gynecology and Cellular & Molecular Medicine; Life Research Institute, Interdisciplinary School of Health Sciences, Professor Emeritus, University of Ottawa; Senior Scientist, Chronic Disease Program, Emeritus Senior Scientist, Ottawa Hospital Research Institute.
Affiliations and expertise
Director, Reproductive Biology Unit, Professor, Department of Obstetrics and Gynaecology and Cellular & Molecular Medicine and the Interdisciplinary School of Health Sciences, University of Ottawa, Canada

JI

Johji Inazawa

Johji Inazawa, MD, PhD, is director/ specially appointed Professor, Research Core Center, Tokyo Medical and Dental University (TMDU), Emeritus Professor, TMDU, Japan.
Affiliations and expertise
Director, Bioresource Research Center, and Professor, Department of Molecular Cytogenetics, Medical Research Institute, Tokyo Medical and Dental University, Japan

MM

Massoud Mirshahi

Massoud Mirshahi, MD, PhD, is Professor, Research INSERM unit, Paris 7 University Paris Diderot, France.
Affiliations and expertise
Professor, Research INSERM unit, Paris 7 University Paris Diderot, France

MP

Marc Pocard

Marc Pocard, MD, PhD, is Director Research INSERM unit, and Professor, Abdominal and Oncologic Surgery, Paris 7 University Paris Diderot, France.
Affiliations and expertise
Professor, Abdominal and Oncologic Surgery, Paris 7 University Paris Diderot, France

CI

Ciro Isidoro

Professor Ciro Isidoro, Clinical Biochemistry and Clinical Molecular Biology, and Professor of Medical Oncology in the Department of Health Sciences, University of Piemonte Orientale, Italy.
Affiliations and expertise
Professor, Clinical Biochemistry and Clinical Molecular Biology, and Professor, Medical Oncology, Department of Health Sciences, University of Piemonte Orientale, Italy

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