Peptide Solvation and H-bonds
- 1st Edition, Volume 72 - March 2, 2006
- Latest edition
- Editors: Robert Baldwin, David James Baker
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 0 3 4 2 7 2 - 3
- eBook ISBN:9 7 8 - 0 - 0 8 - 0 4 6 3 5 6 - 8
Volume 72, Peptide Solvation and H-bonds, addresses the role of peptide backbone solvation in the energetics of protein folding. Particular attention is focused on modeling and co… Read more
Volume 72, Peptide Solvation and H-bonds, addresses the role of peptide backbone solvation in the energetics of protein folding. Particular attention is focused on modeling and computation. This volume will be of particular interest to biophysicists and structural biologists.
- Challenges the longstanding and basic assumptions of structural biology
- Discusses how to solve the problem of protein structure prediction
- Addresses the quantitation of the energetics of folding
Biochemists, biophysicists, cell biologists, protein chemists, and structural biologists
Preface: New Directions in the Study of Peptide H-bonds and Peptide Solvation
1. Potential Functions for Hydrogen Bonds in Protein Structure Prediction and Design
2. Backbone-Backbone H-Bonds Make Context Dependent Contributions to Protein Folding Kinetics and Thermodynamics: Lessons from Amide-to-Ester Mutations
3. Modeling Polarization in Proteins and Protein-Ligand Complexes: Methods and Preliminary Results
4. Hydrogen Bonds in Molecular Mechanics Force Fields
5. Resonance Character of Hydrogen-Bonding Interactions in Water and Other H-Bonded Species
6. How Hydrogen Bonds Shape Membrane Protein Structure
7. Peptide and Protein Folding and Conformational Equilibria: Theoretical Treatment of Electrostatics and Hydrogen Bonding with Implicit Solvent Models
8. Thermodynamics of alpha-Helix Formation
9. The Importance of Cooperative Interactions and A Solid State Paradigm to Proteins – What Peptide Chemists Can Learn from Molecular Crystals
1. Potential Functions for Hydrogen Bonds in Protein Structure Prediction and Design
2. Backbone-Backbone H-Bonds Make Context Dependent Contributions to Protein Folding Kinetics and Thermodynamics: Lessons from Amide-to-Ester Mutations
3. Modeling Polarization in Proteins and Protein-Ligand Complexes: Methods and Preliminary Results
4. Hydrogen Bonds in Molecular Mechanics Force Fields
5. Resonance Character of Hydrogen-Bonding Interactions in Water and Other H-Bonded Species
6. How Hydrogen Bonds Shape Membrane Protein Structure
7. Peptide and Protein Folding and Conformational Equilibria: Theoretical Treatment of Electrostatics and Hydrogen Bonding with Implicit Solvent Models
8. Thermodynamics of alpha-Helix Formation
9. The Importance of Cooperative Interactions and A Solid State Paradigm to Proteins – What Peptide Chemists Can Learn from Molecular Crystals
- Edition: 1
- Latest edition
- Volume: 72
- Published: March 2, 2006
- Language: English
RB
Robert Baldwin
Former Senior Lecturer, Willesden College of Technology, London
Affiliations and expertise
Department of Biochemistry, Stanford Medical School, California, USADB
David James Baker
Affiliations and expertise
Doctor & Consultant Medical Toxicologist, Centre for Radiation, Chemicals and Environmental Hazards (CRCE) (London), Health Protection Agency, London, UKRead Peptide Solvation and H-bonds on ScienceDirect