
Penn Clinical Manual of Urology
- 3rd Edition - March 5, 2023
- Imprint: Elsevier
- Editors: Thomas J. Guzzo, Robert C. Kovell, Justin B. Ziemba, Dana A. Weiss, Alan J. Wein
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 7 7 5 7 5 - 5
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 8 4 3 8 - 0
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 7 7 5 7 6 - 2
Brief, well-illustrated chapters, an easy-to-read format, and a convenient, portable size make Penn Clinical Manual of Urology, 3rd Edition, your go-to resource for fast reference… Read more

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Covers key topics such as recent advances in urologic oncology, including prostate cancer diagnosis and treatment; pelvic surgery; urinary tract function, dysfunction, and reconstruction; and male sexual health.
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Contains self-assessment questions online for every chapter and suggested readings for further study, making it an excellent resource for clinical questions and answers, as well as for exam study.
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Includes new algorithms and suggested core readings, clinical pearls, and updated content on physical examination.
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Highlights new imaging techniques that aid in the identification and treatment of a wide range of urologic issues—from simple to complex.
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Includes an abundance of clinical photos, algorithms, tables, charts, and MRI/CT scans that highlight and clarify the text.
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An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.
- Cover image
- Title page
- Table of Contents
- Copyright
- Dedication
- Contributors
- Preface
- List of Illustrations
- List of Tables
- 1. Signs and symptoms: The initial examination
- Background
- Urologic manifestations of disease
- History
- The physical examination
- The urinalysis and culture
- Initial point-of-care imaging
- Blood tests
- Summary
- Suggested readings
- 2. Diagnostic and interventional uroradiology
- Diagnostic uroradiology
- Plain films (kidney, ureters, and bladder plain radiography)
- Ultrasonography
- Computed tomography
- Intravenous urography
- Retrograde pyeloureterography
- Antegrade pyelography
- Cystography
- Modifications of cystography
- Voiding cystourethrogram
- Retrograde urethrogram
- Loopogram and pouchogram
- Angiography
- Radionuclide imaging
- Interventional uroradiology
- Percutaneous nephrostomy
- Ureteral stenting
- Dilation of ureteral and urethral stenoses
- Percutaneous drainage of renal and related retroperitoneal fluid collections
- Renal cyst aspiration and ablation
- Urinary tract biopsy techniques
- Suggested readings
- 3. Lower urinary tract infections in women and pyelonephritis
- Lower urinary tract infection
- Pyelonephritis
- Suggested readings
- 4. Lower urinary tract infection in males
- Introduction
- Bacterial cystitis
- Prostatitis
- Epididymitis and orchitis
- Antibiotic addendum
- Suggested readings
- 5. Specific infections of the genitourinary tract
- Genitourinary tuberculosis
- Genitourinary schistosomiasis
- Genitourinary fungal infections
- Rare parasitic genitourinary infections
- Other genitourinary infections
- Suggested readings
- 6. Sexually transmitted infections
- Introduction
- Bacterial urethritis
- Epididymitis
- Genital lesions
- Genital herpes
- Syphilis
- Chancroid
- Lymphogranuloma venereum
- Granuloma inguinale
- Molluscum contagiosum
- Vaginitis
- Ectoparasites
- Viral hepatitis
- Zika virus
- Human immunodeficiency virus
- Suggested readings
- 7. Interstitial cystitis/bladder pain syndrome
- Definition
- The hunner lesion
- Epidemiology
- Etiology
- Diagnosis
- Initial management
- Oral therapy
- Intravesical therapy
- Hydrodistention
- Neuromodulation
- Surgical therapy
- Philosophy of management
- Suggested readings
- 8. Urolithiasis in the adult
- Epidemiology
- Composition of renal stones
- Pathogenesis and physiochemical properties
- Stone formation and vascular calcification
- Clinical manifestations of nephrolithiasis
- Evaluation of patients with nephrolithiasis (Fig. 8.1)
- Management of nephrolithiasis
- Additional counseling considerations
- References
- Suggested readings
- 9. Penn clinical manual chapter on urologic emergencies
- Introduction
- Gross hematuria
- Acute urinary retention
- Issues with indwelling foley drainage
- Flank pain and upper tract obstruction
- Postobstructive diuresis
- Oliguria/anuria (AKI)
- Acute scrotum
- Emergent urologic infections
- Priapism
- Penile fracture
- Foreskin
- Foreign bodies
- Spinal cord compression
- Suggested readings
- 10. Urinary and genital trauma
- Introduction
- Kidney injuries
- Ureteral injuries
- Bladder injuries
- Urethral injuries
- Injuries to the male external genitalia
- Injuries to the female genitalia
- Conclusions
- Suggested readings
- 11. Urethral stricture and lower urinary tract reconstruction
- Introduction
- Etiologies
- Urethral anatomy
- Clinical evaluation
- Preoperative evaluation and optimization
- Operative management
- Anterior urethral strictures
- Posterior urethral stenosis
- Devastated urethras or outlets
- Complications of urethral stricture management
- Female urethral strictures
- Suggested readings
- 12. Urinary fistula
- Vesicovaginal fistula
- Ureterovaginal fistula
- Urethrovaginal fistula
- Enterovesical fistula
- Rectourethral fistula
- Other urinary fistula
- Suggested readings
- 13. Nocturia
- Introduction
- Epidemiology
- Nocturia and bother
- Beyond bother: Nocturia and quality of life, morbidity, and mortality
- Causes of nocturia
- Initial evaluation of nocturia
- Treatment
- Suggested readings
- 14. Lower urinary tract function and dysfunction; urinary incontinence
- Introduction
- Relevant lower urinary tract anatomy, physiology, pharmacology, and terminology
- Normal lower urinary tract function
- Abnormalities of filling/storage and emptying/voiding: Overview of pathophysiology (Tables 14.3 and 14.4)
- The neurourologic evaluation (Table 14.5)
- Classification of lower urinary tract dysfunction
- Neurogenic lower urinary tract dysfunction
- Urinary incontinence
- Treatment of lower urinary tract dysfunction
- Suggested readings
- 15. Benign prostatic hyperplasia and related entities
- General considerations
- Definitions and epidemiology
- Prostatic size and morphology pertinent to benign prostatic hyperplasia
- Etiologic theories of benign prostatic hyperplasia: Pathophysiology
- Lower urinary tract symptoms
- Signs of benign prostatic hyperplasia
- Urodynamics of bladder outlet obstruction
- The natural history of benign prostatic hyperplasia and its alteration
- Evaluation of lower urinary tract symptoms suspected to be due to benign prostatic hyperplasia
- Indications for treatment
- Treatment of benign prostatic hyperplasia and related entities
- 16. Adult genitourinary cancer: Prostate and bladder
- Prostate cancer
- Carcinoma of the bladder
- Suggested readings
- 17. Adult genitourinary cancer: Renal and testicular
- Neoplasms of the kidney
- Urothelial tumors of the renal pelvis and ureter
- Testicular tumors
- Suggested readings
- 18. Adult genitourinary cancer: Urethral and penile
- Penile cancer
- Self-assessment questions
- 19. Radiation therapy
- Physics
- Radiobiology
- Treatment planning
- Clinical radiation oncology
- Summary
- Suggested readings
- 20. Laparoscopic surgical anatomy, laparoscopy, and robotic-assisted laparoscopic surgery
- Introduction
- Patient selection
- Patient positioning
- Robotic-assisted laparoscopic prostatectomy
- Other pelvic and upper tract surgery
- Access
- Physiologic changes of pneumoperitoneum
- Trocar placement
- Laparoendoscopic single-site surgery
- Surgical anatomy of the upper urinary tract
- Surgical anatomy of the lower urinary tract
- Complications
- Suggested readings
- 21. Male sexual dysfunction
- Introduction
- Peyronie’s disease
- Physiology of sexual function
- Ejaculatory dysfunction
- Evaluation of sexual dysfunction
- Treatment
- Surgical management of erectile dysfunction
- Types of prostheses
- Suggested readings
- 22. Male fertility and sterility
- Epidemiology
- Reproductive anatomy and physiology
- Gross anatomy
- Reproductive hormonal axis
- Classification of abnormalities
- Evaluation of the infertile male
- Treatment options
- Suggested readings
- 23. Disorders of the adrenal gland
- Adrenal anatomy
- Adrenal physiology
- Adrenal disorders
- Evaluation of adrenal pathology in urologic practice
- Suggested readings
- 24. Retroperitoneal tumors and retroperitoneal fibrosis
- Retroperitoneal anatomy
- Benign diseases of the retroperitoneum
- Malignant pathology of the retroperitoneum
- Suggested readings
- 25. Embryology and differences of sex development
- Normal sexual development
- DSD categories
- Evaluation and management of ambiguous genitalia at birth
- Treatment options and indications
- Gender
- Follow-up
- Suggested readings
- 26. Congenital anomalies
- Upper urinary tract
- Lower urinary tract
- External genital malformations
- Cloacal dysgenesis/persistent cloaca
- Suggested readings
- 27. Pediatric oncology
- Wilms tumor
- Neuroblastoma
- Genitourinary rhabdomyosarcoma
- Testis tumors
- Suggested readings
- 28. Pediatric urolithiasis
- Pediatric nephrolithiasis
- Urinary metabolic abnormalities
- References
- Suggested readings
- 29. Pediatric voiding function and dysfunction
- Basic embryology
- Anatomy and physiology
- The normal voiding cycle
- The clinical manifestations of voiding dysfunction
- The clinical approach to the patient
- Treatment of dysfunctional voiding/elimination by category
- Diabetes insipidus
- Suggested readings
- 30. Transitional urology
- Introduction
- Spina bifida
- Exstrophy-epispadias complex
- Long-term consideration of complex urologic reconstruction
- Hypospadias
- Posterior urethral valves
- Prune belly syndrome
- Urologic issues in childhood cancer survivors
- Suggested readings
- 31. Geriatric urology
- Urology and aging patients
- Special aspects of approach to the geriatric patient
- Therapeutic decisions
- The perioperative period
- Suggested readings
- 32. Quality and safety considerations in urology
- Introduction: What is patient safety and quality improvement?
- Medical error: Consequences and contributing factors
- Creating safety culture in the workplace
- Standardizing health care systems and improving reliability
- Methods of patient safety investigation
- Quality improvement: Principles and methods
- Conclusion
- Suggested readings
- 33. Clinical research design and statistics
- Research question
- Errors in research
- Study design
- Study population
- Variables
- Statistical analysis
- Implementing the study
- Suggested readings
- Index
- Edition: 3
- Published: March 5, 2023
- Imprint: Elsevier
- No. of pages: 1136
- Language: English
- Paperback ISBN: 9780323775755
- eBook ISBN: 9780443284380
- eBook ISBN: 9780323775762
TG
Thomas J. Guzzo
RK
Robert C. Kovell
JZ
Justin B. Ziemba
DW
Dana A. Weiss
AW
Alan J. Wein
Professor and Chair, Division of Urology
University of Pennsylvania Health System