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Paper and Thin Layer Chromatography

  • 4th Edition - January 1, 1976
  • Latest edition
  • Editors: Ivor Smith, J. W. T. Seakins
  • Language: English

Chromatographic & Electrophoretic Techniques, Fourth Edition, Volume I: Paper and Thin Layer Chromatography presents the methods of paper and thin layer chromatography. This… Read more

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Description

Chromatographic & Electrophoretic Techniques, Fourth Edition, Volume I: Paper and Thin Layer Chromatography presents the methods of paper and thin layer chromatography. This book discusses the practical approach in the application of paper and thin layer chromatography techniques in the biological sciences. Organized into 18 chapters, this edition begins with an overview of the clinical aspects related to the detection of those metabolic diseases that can result in serious illness presenting in infancy and early childhood. This text then discusses the three major types of screening for inherited metabolic disorders in which paper or thin-layer chromatography are being used, including screening the healthy newborn population, screening the sick hospitalized child, and screening mentally retarded patients. Other chapters consider the procedures for thin layer chromatography. This book discusses as well the complexity of amino acid mixtures present in natural products. The final chapter deals with the detection of synthetic basic drugs. This book is a valuable resource for chemists and toxicologists.

Table of contents


Editors and Authors

Preface


1. Introduction

(a) The Early History of Chromatography

(b) Introduction to Paper and Thin Layer Chromatography

(c) Chromatography and Screening for Inborn Errors of Metabolism


2. Paper Chromatographic Apparatus and Techniques


3. Thin Layer Chromatography


4. Sources of Error in Paper and Thin Layer Chromatography


5. Aminoacids and Related Compounds

Section 1. Techniques

Section 2. Applications in Clinical Biochemistry


6. Imidazoles


7. Tryptophan Metabolites—TLC


8. Purines, Pyrimidines and Related Compounds


9. Sugars


10. Phenolic Acids


11. Ketoacids


12. Organic Acids


13. Steroids


14. Lipids


15. The Spark Chamber—A Technique for the Rapid Mapping of Radiochromatograms

Toxicological Applications of Chromatography


16. Part 1—Initial Screening and Tentative Identification of Drugs


17. Part 2—Confirmation of Acidic and Neutral Drugs


18. Part 3—Confirmation of Alkaloids and Basic Drugs

Index

Product details

  • Edition: 4
  • Latest edition
  • Published: November 15, 2013
  • Language: English

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