Organic Nanomaterials for Cancer Phototheranostics
- 1st Edition - August 26, 2023
- Editors: Manzar Abbas, Atia Atiq, Muhammad Ovais, Michael R Hamblin
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 9 5 7 5 8 - 8
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 5 7 5 9 - 5
Organic Nanomaterials for Cancer Phototheranostics highlights the use of biocompatible building blocks to make nanomaterials that can aid in medical treatment through better di… Read more

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Request a sales quoteOrganic Nanomaterials for Cancer Phototheranostics highlights the use of biocompatible building blocks to make nanomaterials that can aid in medical treatment through better diagnostic and antitumor efficacy. The book synthesizes the current literature on synthetic strategies and designs based on peptides, proteins, polymers, lipids, and their conjugates, as well as composites and complexes with metals and inorganic components used to form the nanomaterials. Mechanistic approaches, clinical problems, and therapeutic and diagnostics mechanisms are covered in each chapter. Cellular interactions and uptake, pharmacokinetics, biodistribution, drug delivery efficiency, and safety concerns of these types of nanomaterials are also discussed. Other topics cover photostability, clearance, metabolism, in-vitro and in-vivo mechanisms, therapeutic efficacy, imaging, and toxicology.
- Outlines fabrication and design strategies of peptides, proteins, polymers, lipids, composites, and complexes with metals and inorganic components
- Discusses the limitations and challenges of organic nanomaterials in clinical use, including their mechanisms of penetration into cancer cells and tissue, photostability, clearance, and metabolism
- Covers clinical problems and therapeutic and diagnostics mechanisms
Researchers and postgraduate students in the fields of materials science, biomedical engineering, cancer research and nanotechnology. Oncologists interested in novel cancer therapies
- Cover image
- Title page
- Copyright
- Table of Contents
- List of Contributors
- Introduction
- Chapter 1 Contemporary developments, trends, and challenges in cancer phototheranostics
- 1.1 Introduction
- 1.2 Overview of organic nanomaterials
- 1.3 Fundamentals parameters of phototheranostics
- 1.4 Jablonski diagram
- 1.5 Recent developments in organic nanomaterials
- 1.6 Conclusion and future perspectives
- References
- Chapter 2 The role of nanotechnology: Organic nanomaterials and the mechanism of cancer phototheranostics
- 2.1 Introduction
- 2.2 Parameters of nanomaterials influencing cancer phototheranostics
- 2.3 Therapeutic mechanism of molecular drugs in assembled state
- 2.4 FDA-approved organic nanomaterials
- 2.5 Challenges for clinical translation
- 2.6 Conclusion and future perspectives
- References
- Chapter 3 Synthetic strategies of short peptide-modified nanomaterials for diagnostics and phototherapy
- 3.1 Introduction
- 3.2 Physicochemical properties needed for phototheranostics
- 3.3 Molecular design of amino acid and short peptide-based phototheranostics agent
- 3.4 Conclusion and future perspectives
- Acknowledgment
- References
- Chapter 4 Development of metal– peptide composite nanomaterials for diagnosis and phototherapy
- 4.1 Introduction
- 4.2 Molecular design of phototheranostics agents
- 4.3 Molecular design of short peptides with metals for phototheranostics
- 4.4 Conclusion and future perspectives
- Acknowledgments
- References
- Chapter 5 Fabrication of protein-based nanomaterials as photonanomedicine agents
- 5.1 Introduction
- 5.2 Types of proteins used to produce protein nanomaterials
- 5.3 Fabrication of protein-based nanomaterials
- 5.4 Protein-based nanomaterials for PDT and PTT
- 5.5 Protein-based nanomaterials for photoimmunotherapy
- 5.6 Protein-AIEgens nanocomposites
- 5.7 Protein-based nanomaterials for photoacoustic imaging
- 5.8 Conclusion and future perspectives
- References
- Chapter 6 Synthetic strategies of protein–metal nanomaterials as photonanomedicine agents
- 6.1 Introduction
- 6.2 Protein-based nanoparticles
- 6.3 Synthetic strategies of metal–protein-based nanomaterials
- 6.4 Proteins types used to harvest protein–metal nanohybrids
- 6.5 Metal–protein-based nanomaterials as photonanomedicine agents
- 6.6 Conclusion and future perspectives
- References
- Chapter 7 Fabrication of polymeric nanomaterials for phototheranostics of cancer
- 7.1 Introduction
- 7.2 Polymer-based nanoparticles
- 7.3 Polymeric micelles
- 7.4 Liposomes
- 7.5 Nanogels
- 7.6 Dendrimers
- 7.7 Types of phototheragnostic
- 7.8 Conclusion and future perspectives
- References
- Chapter 8 Development of metal–polymer composite nanomaterials for diagnosis and phototherapy
- 8.1 Introduction
- 8.2 Conventional phototherapy methods and their limitations
- 8.3 Recent advances in metal–polymer nanocomposites for diagnosis applications
- 8.4 Recent advances in metal–polymer nanocomposites for phototherapy applications
- 8.5 Challenges and future translational opportunities
- 8.6 Conclusion and future perspectives
- Acknowledgment
- References
- Chapter 9 Lipid-based nanomaterials as phototheranostic agents
- Abbreviations
- 9.1 Introduction
- 9.2 Development and classification of lipidic nanomaterials
- 9.3 Cancer-targeted delivery of lipid nanoparticles
- 9.4 Application of lipid nanoparticles in cancer therapy and imaging
- 9.5 Phototheranostic agent
- 9.6 Application of lipidic nanomaterials in photodynamic therapy
- 9.7 Application of PTA as nanomedicines in clinical trials
- 9.8 Lipidic nanocarriers as phototheranostic agent
- 9.9 Conclusion and future perspectives
- References
- Chapter 10 Safety considerations of organic nanomaterials for phototheranostics
- 10.1 Introduction
- 10.2 Organic nanomaterials as phototheranostic agents: current trends
- 10.3 Safety considerations of organic nanomaterials
- 10.4 Factors affecting the biocompatibility of organic nanomaterials
- 10.5 Conclusion and future perspectives
- References
- Index
- No. of pages: 350
- Language: English
- Edition: 1
- Published: August 26, 2023
- Imprint: Woodhead Publishing
- Paperback ISBN: 9780323957588
- eBook ISBN: 9780323957595
MA
Manzar Abbas
AA
Atia Atiq
MO
Muhammad Ovais
MH