Nutrition and Cancer

1st Edition, Volume 373 - October 11, 2022
Imprint: Academic Press
Editors: Aitziber Buque Martinez, Lorenzo Galluzzi
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 9 0 3 8 8 - 2
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 9 0 3 8 9 - 9

Nutrition and Cancer, Volume 373 presents a collection of chapters that describe the effect of different metabolic situations, their contribution to metabolic modulation, and th… Read more

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Nutrition and Cancer, Volume 373 presents a collection of chapters that describe the effect of different metabolic situations, their contribution to metabolic modulation, and their impact on tumor growth. Specific chapters in this release include Impact of obesity on cancer progression and treatment, Impact of dietary protein on cancer progression and treatment, Fasting mimicking diet and cancer therapy, Fasting and cancer responses to chemotherapy, Dietary polyamines and cancer, Ketogenic diets and cancer therapy, and Nutritional and metabolic approaches to target OXPHOS and glycolysis in cancer cells.

Cover
Title page
Table of Contents
Copyright
Contributors
Emergent impact of lifestyle on tumor progression and response to therapy
References
Chapter One: Modifying dietary amino acids in cancer patients
Abstract
1: Introduction
2: Reducing availability of NEAAs as an anti-cancer approach
3: Role of essential AAs in cancer biology
4: Altering dietary protein to limit tumor growth and enhance cancer therapy
5: Role of bacteria in mediating the pro-tumorigenic effects of dietary AAs
6: Current recommendations for protein intake in cancer patients
7: Considerations for evaluating the impact of modifying AA intake on treatment response and outcomes in patients with cancer
References
Chapter Two: Targeting amino acid metabolism in cancer
Abstract
1: Introduction
2: Asparagine
3: Arginine
4: Methionine
5: Cysteine
6: Concluding remarks
Acknowledgments
References
Chapter Three: Fasting and cancer: from yeast to mammals
Abstract
1: Introduction
2: Calorie restriction
3: Fasting and fasting mimicking diets
4: Fasting mimicking diets and cancer
5: Fasting-mimicking diets and non-toxic interventions to kill cancer cells
6: Fasting-mimicking diets in clinical oncology
Acknowledgments
References
Chapter Four: Fasting and cancer responses to therapy
Abstract
1: Introduction
2: Nutrients restriction in rodents and humans
3: Calorie restriction in cancer therapy
4: Alternative approaches to fasting and CR in cancer therapy
5: Conclusion
References
Chapter Five: Autophagy-inducing nutritional interventions in experimental and clinical oncology
Abstract
1: Introduction
2: Fasting and caloric restriction
3: Methionine restriction
4: Ketogenic diets
5: Nicotinamide-adenine dinucleotide: focus on nicotinamide
6: Mechanism: Immune, autophagy
7: Spermidine supplementation
8: Conclusions and perspectives
References
Chapter Six: Combination strategies to target metabolic flexibility in cancer
Abstract
1: Introduction
2: Cancer flexibility in metabolite utilization
3: The detrimental collaboration of energy-producing pathways in cancer cells
4: Conclusions and perspective
References

Aitziber Buque Martinez

Aitziber Buqué is currently a Post-Doctoral Associate with the Galluzzi Lab, in the Department of Radiation Oncology at Weill Cornell Medical College (New York), where she investigates innate and acquired mechanisms of resistance to immunotherapy in HR+ breast cancer and radiotherapy as a means to overcome them. Prior to joining the Galluzzi Lab (2018), Aitziber was a Post-Doctoral Associate with the Kroemer Lab in the Cordeliers Research Center (Paris, France; 2014-2018), after receiving her M.Sc. in Bioinformatics and Computational Biology (2006) from the Complutense University (Madrid, Spain) and her Ph.D. in Biomedicine (2013) from the BioCruces Research Institute (Barakaldo, Spain). Aitziber has a long-standing interest in the immunological mechanisms controlling cancer progression and response to treatment.

Affiliations and expertise

Postdoctoral Associate in Radiation Oncology, Radiation Oncology, Weill Cornell Medical College, NY, USA

Lorenzo Galluzzi

Lorenzo Galluzzi is Assistant Professor of Cell Biology in Radiation Oncology at the Department of Radiation Oncology of the Weill Cornell Medical College, Honorary Assistant Professor Adjunct with the Department of Dermatology of the Yale School of Medicine, Honorary Associate Professor with the Faculty of Medicine of the University of Paris, and Faculty Member with the Graduate School of Biomedical Sciences and Biotechnology of the University of Ferrara, the Graduate School of Pharmacological Sciences of the University of Padova, and the Graduate School of Network Oncology and Precision Medicine of the University of Rome “La Sapienza”. Moreover, he is Associate Director of the European Academy for Tumor Immunology and Founding Member of the European Research Institute for Integrated Cellular Pathology. Galluzzi is best known for major experimental and conceptual contributions to the fields of cell death, autophagy, tumor metabolism and tumor immunology. He has published over 450 articles in international peer-reviewed journals and is the Editor-in-Chief of four journals: OncoImmunology (which he co-founded in 2011), International Review of Cell and Molecular Biology, Methods in Cell biology, and Molecular and Cellular Oncology (which he co-founded in 2013). Additionally, he serves as Founding Editor for Microbial Cell and Cell Stress, and Associate Editor for Cell Death and Disease, Pharmacological Research and iScience.

Affiliations and expertise

Assistant Professor of Cell Biology in Radiation Oncology, Department of Radiation Oncology, Weill Cornell Medical College, NY, USA

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