
Nutraceutical Fruits and Foods for Neurodegenerative Disorders
- 1st Edition - November 21, 2023
- Imprint: Academic Press
- Editors: Raj K. Keservani, Rajesh K. Kesharwani, Mila Emerald, Anil K. Sharma
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 1 8 9 5 1 - 7
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 8 9 5 2 - 4
Nutraceutical Fruits and Foods for Neurodegenerative Disorders presents food-based strategies, specifically related to nutraceuticals, in delaying the onset and slowing down of the… Read more

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Request a sales quoteNutraceutical Fruits and Foods for Neurodegenerative Disorders presents food-based strategies, specifically related to nutraceuticals, in delaying the onset and slowing down of the propensity of neuronal devastation. In addition to highlighting the positive effects of nutraceutical fruits and foods on brain health, the book also explores the medicinal properties of fruits, vegetables, berries and nutraceuticals, along with their contribution to environmental factors, potential hazards and the need for specific regulatory actions. This book will be a welcomed reference for nutrition researchers, dieticians, nutritionists and academicians studying related fields.
- Presents the positive aspects of nutraceutical fruits and food effect on brain health
- Highlights the structure activity relationship of constituents present in nutraceuticals in the treatment and cure of neurodegenerative diseases
- Explores the nuances of novelty in dosage form design, production, authentication, quality control and market authorization of nutraceuticals
Nutrition researchers, dieticians, nutritionists, academicians studying related fields
- Cover image
- Title page
- Table of Contents
- Copyright
- List of contributors
- Chapter 1. Role of fruit and food components in brain cognition
- Abstract
- 1.1 Introduction
- 1.2 Brain food and its components
- 1.3 The role of micronutrients in the brain
- 1.4 Conclusion
- Acknowledgment
- Conflict of interest
- References
- Chapter 2. Nutraceutical fruits and foods: local wisdoms in Indochina
- Abstract
- 2.1 Introduction
- 2.2 Nutraceuticals in neurological disorder
- 2.3 Complementary and alternative medicine and nutraceutical fruits and foods
- 2.4 Local wisdom on nutraceutical fruits and foods
- 2.5 Health-care local wisdom in Indochina
- 2.6 Conclusion
- References
- Chapter 3. Functional food for mitochondrial dysfunction and autophagy in neurodegenerative diseases
- Abstract
- 3.1 Introduction
- 3.2 Neurodegenerative disease
- 3.3 Normal mitochondrial function
- 3.4 Evidence for mitochondrial dysfunction in neurodegenerative disease
- 3.5 Functional food
- 3.6 Conclusion
- References
- Chapter 4. Fruits and foods to improve kids brain health
- Abstract
- 4.1 Introduction
- 4.2 Neurodegenerative disease related to kid's brain health
- 4.3 Types of neurodegenerative disorders
- 4.4 Nutraceuticals for kid's brain health
- 4.5 Conclusion
- References
- Further Reading
- Chapter 5. Memory-boosting fruits and foods for elderly
- Abstract
- 5.1 Introduction
- 5.2 Indian medicine system
- 5.3 Traditional Chinese medicine system
- 5.4 Traditional Iranian medicine system
- 5.5 Herbal drugs used in memory enhancement
- 5.6 Conclusion
- Conflict of interest
- References
- Chapter 6. Role of functional foods and nutraceuticals for depression, post-traumatic stress disorder, and suicidal behaviors
- Abstract
- 6.1 Introduction
- 6.2 Mental disorders
- 6.3 Types of mental disorders
- 6.4 Mechanisms of mental disorders induction
- 6.5 Antidepressants and their mode of actions
- 6.6 Post-traumatic stress disorder and their mode of action
- 6.7 Suicidal behaviors and their mode of action
- 6.8 Side effects of existing drugs
- 6.9 Role of the brain-gut-microbiota axis in mental disorders
- 6.10 Classification of nutraceuticals
- 6.11 Other commonly found nutraceuticals
- 6.12 Nutraceuticals for the management of mental disorders
- 6.13 Side effects of nutraceutical supplementation
- 6.14 New treatment regimen: nutraceuticals as gut microbiota modulators
- 6.15 Conclusion
- References
- Chapter 7. Nutraceuticals for prevention and management of anxiety
- Abstract
- 7.1 Introduction
- 7.2 Nutraceuticals: role in anxiety and depression
- 7.3 Herbal based medicines for prevention of anxiety and stress
- 7.4 Medicinal plants as an anxiolytic agent
- 7.5 Nutritional supplements
- 7.6 Omega 3 adenosyl-methionine
- 7.7 Conclusions and future directions
- Acknowledgments
- Conflict of interest
- References
- Chapter 8. Importance of functional foods in the management of autism
- Abstract
- 8.1 Introduction
- 8.2 Diet and the development of autism spectrum disorder
- 8.3 Treatment for autism spectrum disorder
- 8.4 The gluten-free and casein-free diet
- 8.5 Conclusion
- Conflict of interest
- References
- Further reading
- Chapter 9. Role of probiotics in brain health
- Abstract
- 9.1 Introduction
- 9.2 Probiotics
- 9.3 Probiotics and brain health
- 9.4 Role of probiotics on major neurological diseases
- 9.5 Conclusion
- List of abbreviations
- Author contributions
- Acknowledgments
- References
- Chapter 10. Nutraceutical’s potentials in neurodegenerative disease
- Abstract
- 10.1 Introduction
- 10.2 Neurodegenerative disease
- 10.3 Mechanism of neurotoxicity
- 10.4 Nutraceuticals in neurodegenerative disease
- 10.5 Role of various nutraceuticals in neurodegenerative diseases
- 10.6 Conclusion and future perspectives
- References
- Chapter 11. Neuroprotective effect of dietary polyphenols
- Abstract
- 11.1 Introduction
- 11.2 Classes of polyphenols
- 11.3 Signaling pathways
- 11.4 Future prospects
- 11.5 Conclusion
- References
- Chapter 12. Herbal nutraceuticals in health and neurodegenerative diseases
- Abstract
- 12.1 Herbal nutraceuticals and brain function in health and neurodegenerative diseases
- 12.2 Herbal nutraceutical
- 12.3 Chief constituents of herbal extract
- 12.4 The chief component of herbal nutraceutical and neurodegenerative diseases, any link?
- 12.5 Conclusion
- References
- Chapter 13. Effect of nutrients on brain function
- Abstract
- 13.1 Introduction
- 13.2 Nutrition’s influence on brain function
- 13.3 Food calories and mental performance
- 13.4 Antioxidant foods
- 13.5 Epigenetics and diet
- 13.6 Future prospects
- 13.7 Conclusion
- Acknowledgement
- Conflict of interest
- References
- Chapter 14. Effect of plant-based diets on the brain
- Abstract
- 14.1 Introduction
- 14.2 Neurodegenerative disorders
- 14.3 Types of neurodegenerative and cardiovascular disorders
- 14.4 Nutraceutical products: a promising medication source for neurodegenerative diseases
- 14.5 Conclusion
- References
- Further reading
- Chapter 15. Role of dietary fibers in the management of hypertension and its association with neurodegeneration
- Abstract
- 15.1 Introduction
- 15.2 Mechanisms of development of neurodegenerative diseases
- 15.3 Hypertension
- 15.4 Types of hypertensions
- 15.5 Secondary hypertension
- 15.6 Some other types of hypertension
- 15.7 Resistant hypertension
- 15.8 Malignant hypertension
- 15.9 Isolated systolic hypertension
- 15.10 Hypertension and neurodegeneration
- 15.11 Dietary fiber
- 15.12 Applications
- 15.13 Dietary fibers used in management of hypertension
- 15.14 Risk factors and prevention of hypertension
- 15.15 Modifiable risk factors for hypertension
- 15.16 Role of dietary fiber in the management of hypertension
- 15.17 Conclusion
- References
- Chapter 16. Potentials of berries and pomegranate in management of the neurodegenerative disorders
- Abstract
- 16.1 Introduction
- 16.2 Constituents of pomegranate and berries
- 16.3 Role of berries and pomegranate in neurodegenerative disorders
- 16.4 Effect of pomegranate on Parkinson's disease
- 16.5 Athero-preventive effects of blueberries
- 16.6 Influencing gut microbiota
- 16.7 Multiple sclerosis
- 16.8 EPILEPSY
- 16.9 Neurobehavioral abnormalities
- 16.10 Conclusion
- References
- Chapter 17. Effect of green tea on human brain health
- Abstract
- 17.1 Introduction
- 17.2 Chemical constituents
- 17.3 Green tea effects on neurodegenerative diseases
- 17.4 Neuroprotective action of green tea
- 17.5 Commercial and clinical perspective
- 17.6 Future perspective
- 17.7 Conclusion
- References
- Chapter 18. Role of garlic and onion for better cognition and maintenance of neurodegenerative diseases
- Abstract
- 18.1 Introduction
- 18.2 Neurodegeneration
- 18.3 Phytochemical constituents present in garlic
- 18.4 Pathophysiology and pharmacology
- 18.5 Toxicological studies
- 18.6 Onion and its phytoconstituents
- 18.7 Conclusion
- References
- Chapter 19. Role of antioxidants in neutralizing oxidative stress
- Abstract
- 19.1 Introduction
- 19.2 Oxidants
- 19.3 Reactive oxygen species
- 19.4 Reactive nitrogen species
- 19.5 Generation of free radicals
- 19.6 Endogenous sources of oxidants
- 19.7 Exogenous source of oxidants
- 19.8 Exercises
- 19.9 Cigarette smoke
- 19.10 Ozone exposure
- 19.11 Hyperoxia
- 19.12 Ionizing radiation
- 19.13 Heavy metal ions
- 19.14 Oxidative stress
- 19.15 Mechanisms of cell signaling mediated by reactive oxygen species/reactive nitrogen specie
- 19.16 Antioxidants
- 19.17 Enzymatic antioxidants
- 19.18 Nutritional antioxidants
- 19.19 Vitamin C
- 19.20 Vitamin E
- 19.21 Prooxidant agents
- 19.22 Ascorbic acid
- 19.23 Polyphenols
- 19.24 Flavonoids and essential oils
- 19.25 Flavanols flavanones isoflavones
- 19.26 Gingerols gingerenone
- 19.27 Genistein
- 19.28 Genistein
- 19.29 Aesculetin
- 19.30 Aesculetin
- 19.31 Curcumin
- 19.32 Resveratrol
- 19.33 Resveratrol
- 19.34 Selenium
- 19.35 Radiation therapy
- 19.36 Conclusions
- References
- Chapter 20. Nutraceutical interventions in Alzheimer's disease
- Abstract
- 20.1 Introduction
- 20.2 Factors responsible for neurodegenerative disorder
- 20.3 Progression of neurodegenerative disease stages
- 20.4 Retrogenesis
- 20.5 Cognitive dysfunction
- 20.6 Gait abnormality
- 20.7 Nutraceuticals to prevent or mitigate neurodegeneration
- 20.8 Alzheimer’s disease
- 20.9 Etiology and pathophysiology of Alzheimer’s disease
- 20.10 Current treatments and remedies
- 20.11 Flavonoids
- 20.12 Saffron and its constituents
- 20.13 Adjuvant therapy in Alzheimer disease
- 20.14 Bacosides
- 20.15 Quercetin
- 20.16 Ashwagandha
- 20.17 Omega 3 denosyl-methionine
- 20.18 Parkinson’s disease
- 20.19 Vitamins
- 20.20 Polyphenol stilbenes
- 20.21 Resveratrol
- 20.22 Oxyresveratrol
- 20.23 Phytoestrogens
- 20.24 Ginsenoside
- 20.25 Genistein
- 20.26 Polyphenolic compounds
- 20.27 Catechins in green tea
- 20.28 Curcuminoids
- 20.29 Baicalein
- 20.30 Adjuvant therapy in Parkinsonism disease
- 20.31 Omega-3 fatty acids
- References
- Chapter 21. Nutraceuticals and gutbiota-brain axis
- Abstract
- 21.1 Introduction
- 21.2 Mechanism involved in the microbiota-gut-brain axis
- 21.3 Effect of antibiotics on gut bacteria
- 21.4 Dietary nutrients and their effect on gut-brain axis
- 21.5 Omega 3-fatty acids
- 21.6 Probiotics
- 21.7 Conclusion
- References
- Chapter 22. Nutraceuticals regulation: an overview of the regulatory frameworks in USA, EU, and Japan
- Abstract
- 22.1 Introduction
- 22.2 Nutraceuticals regulations in the USA
- 22.3 Nutraceutical regulations in the EU
- 22.4 Nutraceuticals regulations in Japan
- References
- Chapter 23. Nutraceuticals in the management of Parkinson’s disease and dementia
- Abstract
- 23.1 Introduction
- 23.2 Conclusion
- References
- Chapter 24. Scrutinizing the landscape of DNA methylation epigenetic face(s) in glioblastomas
- Abstract
- 24.1 Introduction
- 24.2 Part 1
- 24.3 Part 2
- 24.4 Perspective
- 24.5 Future prospective
- Acknowledgment
- Author contributions
- Funding
- Conflicts of interest
- Availability of data and materials
- Declaration of interest
- Compliance with ethical standards/Ethics approval
- Consent to participate
- Consent to publish
- Abbreviations
- References
- Chapter 25. Role of protein-rich diet in brain functions
- Abstract
- 25.1 Introduction
- 25.2 Sensitivity to protein contained in diet
- 25.3 A high-protein diet sends signals to the nucleus tractus solitarius
- 25.4 Dietary protein and brain centers of homeostatic regulation
- 25.5 The role of reward centers in protein regulation
- 25.6 Mechanism by which proteins can control the reward and food intake
- 25.7 Cognitive effects of vagal nerve stimulation
- 25.8 Nutrient effects on cognition
- 25.9 Caloric intake and cognition
- 25.10 Control of protein intake
- 25.11 Conclusion and future prospects
- Acknowledgement
- References
- Chapter 26. Therapeutic potential of nutraceuticals for the management of neurodegenerative disorders
- Abstract
- 26.1 Introduction
- 26.2 Polyphenolic flavonoid
- 26.3 Nonflavonoid polyphenols as neuroprotective agents
- 26.4 Phenolic acids and diterpenes having significant neuroprotective properties
- 26.5 Organosulfur compounds and conjugated polyenes as neuroprotective agents
- 26.6 Amino acid derivative as neuroprotective agent
- 26.7 Conclusions
- References
- Chapter 27. Nutraceuticals and anxiety
- Abstract
- 27.1 Introduction
- 27.2 Types of anxiety
- 27.3 Causes of anxiety disorder
- 27.4 Drugs used in treatment of anxiety
- 27.5 Mechanisms involved in anxiety
- 27.6 Role of neurotransmitters in some neurological (mental) disorder
- 27.7 Nutraceuticals as potential anxiolytics
- 27.8 Side effects of nutraceuticals
- References
- Chapter 28. Pomegranate and berries as source of bioactive compounds for neurodegenerative disorders
- Abstract
- 28.1 Introduction
- 28.2 Pomegranate fruit
- 28.3 Boysenberries
- 28.4 Choqueberries
- 28.5 Cloudberries
- 28.6 Cranberries
- 28.7 Bilberries
- 28.8 Elderberries
- 28.9 Goji berries
- 28.10 Final remarks
- References
- Index
- Edition: 1
- Published: November 21, 2023
- Imprint: Academic Press
- No. of pages: 596
- Language: English
- Paperback ISBN: 9780443189517
- eBook ISBN: 9780443189524
RK
Raj K. Keservani
Raj K. Keservani, MPharm, is a Faculty of B. Pharmacy, CSM Group of Institutions, Allahabad, India. He has more than 12 years of academic (teaching) experience from various institutes of India in pharmaceutical education. He has published 31 peer-reviewed papers in the field of pharmaceutical sciences in national and international journals, 43 book chapters, three co-authored books, and 18 edited books. He is also active as a reviewer for several international scientific journals. Mr. Keservani graduated with a pharmacy degree from the Department of Pharmacy, Kumaun University, Nainital (Uttarakhand), India. He received his Master of Pharmacy (MPharm) (specialization in pharmaceutics) from the School of Pharmaceutical Sciences, Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal, India. Mr. Keservani is a life member of Society of Pharmaceutical Education and Research (SPER). His research interests include nutraceutical and functional foods, novel drug delivery systems (NDDS), transdermal drug delivery/drug delivery, health science, cancer biology, and neurobiology.
Affiliations and expertise
Faculty of B. Pharmacy, CSM Group of Institutions India, IndiaRK
Rajesh K. Kesharwani
Rajesh K. Kesharwani, PhD, MTech, has more than 10 years of research and eight years of teaching experience at various institutes of India, imparting bioinformatics, and biotechnology education. He has received several awards, including the NASI-Swarna Jayanti Puruskar by The National Academy of Sciences of India. He has supervised PhD, postgraduate, and undergraduate students for their research work and has authored over 40 peer-reviewed articles, 20 book chapters, and 11 edited books with international publishers. Dr. Kesharwani received his PhD from the Indian Institute of Information Technology, Allahabad, India, and worked at NIT Warangal. He has been a recipient of the Ministry of Human Resource Development (India) Fellowship and Senior Research Fellowship from the Indian Council of Medical Research, India. His research fields of interest are medical informatics, protein structure and function prediction, computer-aided drug designing, structural biology, drug delivery, cancer biology, nano-biotechnology, and biomedical sciences.
Affiliations and expertise
Nehru Gram Bharati, IndiaME
Mila Emerald
Prof. Mila Emerald, Ph.D., Dr. Sc., President and CEO at PHYTOCEUTICALS International ™ & NOVOTEK Global Solutions ™, Ph.D. in Cellular Biochemistry and Molecular Biophysics, Dr. Science in Neuroscience, and professorship from the Cornell University, dedicated her life to research of nutraceuticals and natural products, their therapeutic properties, and applications. Her work, business, and research are dedicated to the role of natural nanomaterials and novel drugs delivery systems, in nutraceuticals, fermented products, functional foods, probiotics, essential oils and natural extracts complexes, and their crucial role in human wellbeing and health. She is also focused on the natural compounds, which can potentially be used in prevention and maintenance of bacterial, fungal, as well as viral pathogens, including SARS-COV2. Dr. M. Emerald is honoured to be one of the winners in the International Challenge called: “Next Great Impossible” on Nanotechnology, by Sigma-Aldrich/Merck, one of the most viewed profiles on the LinkedIn.
Affiliations and expertise
Phytoceuticals International, CanadaAS
Anil K. Sharma
Anil K. Sharma, PhD, MPharm, is working as an assistant professor at the Department of Pharmacy, School of Medical and Allied Sciences, GD Goenka University, Gurugram, India. He has more than ten years of academic experience in pharmaceutical sciences. He has published 35 peer-reviewed papers in the field of pharmaceutical sciences in national and international journals as well as 28 book chapters. In addition, he has edited 16 books with reputable publishers. He received a bachelor’s degree in pharmacy from the University of Rajasthan, Jaipur, India, and a Master of Pharmacy degree from the School of Pharmaceutical Sciences, Rajiv Gandhi ProudyogikiVishwavidyalaya, Bhopal, India, with a specialization in pharmaceutics. He earned his PhD in pharmacy from the University of Delhi, India.His research interests encompass nutraceutical and functional foods, novel drug delivery systems (NDDS), drug delivery, nanotechnology, health science/life science, and biology/cancer biology/neurobiology.
Affiliations and expertise
Assistant professor, Department of Pharmacy, School of Medical and Allied Sciences, GD Goenka University, Gurugram, IndiaRead Nutraceutical Fruits and Foods for Neurodegenerative Disorders on ScienceDirect