New and Future Developments in Microbial Biotechnology and Bioengineering

Recent Advances in Application of Fungi and Fungal Metabolites: Current Aspects

1st Edition - September 21, 2020
Imprint: Elsevier
Editors: Joginder Singh Panwar, Praveen Gehlot
Language: English
Hardback ISBN:
9 7 8 - 0 - 1 2 - 8 2 1 0 0 5 - 5
eBook ISBN:
9 7 8 - 0 - 1 2 - 8 2 2 5 5 7 - 8

New and Future Developments in Microbial Biotechnology and Bioengineering presents an account of recent developments and applied aspects of fungi and its metabolites for human wel… Read more

Purchase options

BLOOM INTO SPRING SAVINGS

Save up to 25% on books and eBooks!

Shop now

Institutional subscription on ScienceDirect

Request a sales quote

New and Future Developments in Microbial Biotechnology and Bioengineering presents an account of recent developments and applied aspects of fungi and its metabolites for human welfare. The fungi and its metabolites are employed in diverse fields of agri-food, biochemistry, chemical engineering, diagnostics, pharmaceuticals and medical device development. The book contains chapters by the eminent researchers working with fungi and fungal metabolites who explain their importance and potential in manifold prospects. The book includes a description of various fungal metabolites and their chemistry and biotechnology.

Cover image
Title page
Table of Contents
Copyright
Contributors
Chapter 1: Fungal metabolites: A recent trend and its potential biotechnological applications
Abstract
Acknowledgements
Competing interests
1.1: Introduction
1.2: Maximization of the production of fungal metabolites
1.3: Fungal metabolites
1.4: Fungal mycotoxins
1.5: Limitations and future prospects
1.6: Conclusion
Chapter 2: Fungal resources: Current utilization, future prospects, and challenges
Abstract
2.1: Introduction
2.2: Bioactive compounds
2.3: Biological control
2.4: Edible fungi
2.5: Enzymes
2.6: Fungi as fungicide
2.7: Mycotoxins
2.8: Pigments
2.9: Conclusion
Chapter 3: Role of fungal secondary metabolites in plant protection
Abstract
3.1: Introduction
3.2: Classification of fungi
3.3: Types of metabolites
3.4: Classes of fungal secondary metabolites
3.5: The shikimic acid pathway
3.6: The acetate pathway
3.7: The MVA and MEP pathways
3.8: Fungus-plant interaction
3.9: A glimpse of commercially important metabolites from fungi
3.10: Utility of fungal secondary metabolites in plants
3.11: Conclusion
Chapter 4: Recent advancement and biomedical applications of fungal metabolites
Abstract
4.1: Introduction and historical aspects of fungi
4.2: Fungal metabolites
4.3: Biosynthesis of fungal metabolites
4.4: Pharmacological actions of metabolites
4.5: Clinical applications
4.6: Safety and toxicity issues of fungal metabolites
4.7: Concluding remarks and future perspectives
Chapter 5: Thermophilic fungi: Diversity, physiology, genetics, and applications
Abstract
5.1: Introduction
5.2: Diversity
5.3: Physiology
5.4: Genetics
5.5: Applications
5.6: Conclusions
Chapter 6: Endophytic fungi: Novel source of bioactive fungal metabolites
Abstract
6.1: Endophyte
6.2: Characteristic features of endophytic fungi
6.3: Host specificity
6.4: Bioactive compounds from endophytic fungi
6.5: Endophytic fungi producing anticancer compounds
6.6: Antifungal compounds
6.7: Antibacterial compounds
6.8: Antioxidant Compounds
6.9: Insecticidal compounds
6.10: Antiparasitic compounds
6.11: Antiviral compounds
6.12: Antitubercular compounds
6.13: Immunomodulatory compounds
6.14: Role of endophytic fungi
6.15: Cocultivation
6.16: Epigenetic modulations
6.17: Conclusions
Chapter 7: Lichens: Fungal symbionts and their secondary metabolites
Abstract
Acknowledgments
7.1: Introduction
7.2: Lichens: A composite plant group
7.3: Lichens: An emerging and promising source for secondary metabolites
7.4: Lichens: Fungal enigmatic organisms
7.5: Bioprospective values of lichens
7.6: Lichens: Medicinal boon
7.7: Lichen acids as a potential bactericidal compound
7.8: Lichen acids as a potential fungicidal compound
Chapter 8: Lichen as nature’s basket full of bioactive compounds
Abstract
Acknowledgments
Conflicts of interest
8.1: Introduction
8.2: Classification of lichens
8.3: Pathways for the biosynthesis of secondary metabolite production
8.4: Methods for isolating lichen metabolites
8.5: Properties of lichen metabolites
8.6: Lichen biotechnology
8.7: Recombinant lichen biology
8.8: Future prospects
Chapter 9: Septin proteins and their role in fungi and yeast
Abstract
9.1: Introduction
9.2: General structure of septins
9.3: Septins in yeast
9.4: Regulation of septins
9.5: Role of septins in fungal systems
9.6: Septins in other fungi
Chapter 10: Bioactive terpenoids from mushrooms
Abstract
10.1: Introduction
10.2: Classification of terpenoids and their abundance in basidiomycetes
10.3: Monoterpenoids
10.4: Sesquiterpenoids
10.5: Diterpenoids
10.6: Triterpenoids
10.7: Conclusion
Chapter 11: Arbuscular mycorrhizal fungi: Source of secondary metabolite production in medicinal plants
Abstract
Acknowledgments
11.1: Introduction
11.2: Arbuscular mycorrhizal symbiosis under root organ culture
11.3: Production of bioactive compounds in AMF colonized plants
11.4: AMF-colonized plants: Mechanism of secondary metabolite production
11.5: Conclusion and perspectives
Chapter 12: Endophytic fungal metabolites of medicinal plants and their bioactive properties
Abstract
Acknowledgments
Conflict of interest
12.1: Introduction
12.2: Natural products—A source of potentially bioactive compounds
12.3: Endophytic fungi from medicinal plants
12.4: Secondary bioactive metabolites from fungal endophytes
12.5: Bioactivity of metabolites derived from the endophytic fungi of medicinal plants
12.6: Antimicrobial metabolites from endophytic fungi
12.7: Anticancer metabolites from endophytic fungi
12.8: Antioxidant activities of endophytic fungi
12.9: Conclusion
Chapter 13: Bioactive natural products of endophytic fungal origin: Production, activity and biotechnology
Abstract
Acknowledgment
Conflict of interests
13.1: Introduction
13.2: Methodology
13.3: Endophytic fungi and their potential role in the agriculture industry
13.4: Endophytic fungi-mediated phytopathogen management
13.5: Endophytic fungi and host plant association and the effect on growth and nutrition uptake
13.6: Role of endophytic fungi in bioactive secondary metabolite synthesis
13.7: Bioactivity of metabolites harvested from endophytic fungi
13.8: Discussion: Product optimization, current bottlenecks, and future perspectives
13.9: Conclusion
Chapter 14: Genus Penicillium: Advances and application in the modern era
Abstract
14.1: Introduction
14.2: Penicillium, the reservoir of secondary metabolites
14.3: Application of Penicillium metabolites in modern times
14.4: Penicillium sp. in allergic bronchopulmonary mycosis
14.5: Future prospects
Chapter 15: Aspergillus terreus: Taxonomy, biology, and bioactive secondary metabolites with potential applications
Abstract
15.1: Introduction
15.2: Major bioactive secondary metabolites
15.3: Genetic modifications to trigger the production of SMs
15.4: Activating the silent pathway through the PKS-NRPS gene for high SM production
15.5: Kojic acid and its use in the food and fermentation industries
15.6: A. terreus: Medicinal and pharmaceutical uses
15.7: A. terreus in bioremediation
15.8: Conclusions and future prospects
Chapter 16: Bioprospect potential of gasteroid mushrooms of the genus Astraeus
Abstract
Acknowledgment
16.1: Introduction
16.2: Nutritional and nutraceutical potential
16.3: Antimicrobial and therapeutic potential
16.4: Bioactive metabolites
16.5: Conclusions
Chapter 17: Chemical creativity of Termitomyces mushrooms
Abstract
17.1: Bipotentialities of Termitomyces Heim
17.2: Biomedical applications of Termitomyces lipids
17.3: Conclusions and prospects
Chapter 18: The role of antioxidants and ROS scavenging machinery in wild mushrooms
Abstract
18.1: Introduction
18.2: Nutritional and medicinal value of wild mushrooms
18.3: Some wild edible mushrooms with antioxidant properties
18.4: Endogenous antioxidant defense system in mushrooms
18.5: Antioxidative scavenging machinery in wild mushrooms
18.6: Antioxidant compounds of wild mushrooms
18.7: Conclusion
Chapter 19: Mycotoxin metabolites of fungi
Abstract
19.1: Introduction
19.2: Mycotoxin metabolites
19.3: Occurrence of mycotoxins
19.4: Toxicological properties of mycotoxin
19.5: Mechanism of action
19.6: Conclusions
Chapter 20: Mechanistic evaluation of bioremediation properties of fungi
Abstract
20.1: Introduction
20.2: Bioremediation potential of fungi: Phylum level diversity
20.3: Basic degradation mechanism
20.4: Pollutant-specific approach
20.5: Enzyme-specific degradation approach
20.6: Future perspective of mycoremediation
Index

Joginder Singh Panwar

Prof. Joginder Singh is a Professor at the Department of Botany, Nagaland University, Lumami, Nagaland, India. Previously, he worked as a Professor in the School of Bioengineering and Biosciences, Lovely Professional University and also as a Young Scientist at Microbial Biotechnology and Biofertilizer Laboratory, Department of Botany, Jai Narain Vyas University on a research project funded by the Department of Science and Technology, Government of India. He is an active member of various scientific societies and organizations, including the Association of Microbiologists of India, the Indian Society of Salinity Research Scientists, the Indian Society for Radiation Biology, and the European Federation of Biotechnology. He has published extensively with Elsevier and Springer both in journals and books. He serves as a reviewer for many prestigious journals, including Current Research in Engineering, Science and Technology; Journal of Cleaner Production; Science of the Total Environment; Environmental Monitoring and Assessment; Pedosphere; Soil and Sediment Contamination; Symbiosis; International Journal of Phytoremediation; Ecotoxicology and Environmental Safety; Annals of Agricultural Sciences; and Annals of the Brazilian Academy of Sciences.

Affiliations and expertise

Professor, Department of Botany, Nagaland University, Nagaland, India

Praveen Gehlot

Dr. Praveen Gehlot is Associate Professor, Department of Botany, Jai Narain Vyas University Jodhpur. He did his PhD from JNV University Jodhpur, under the able guidance of Prof. D.K. Purohit. He has about 18 years of teaching and research experience. He has been an awardee of Young Scientist under FAST Track Scheme by Department of Science and Technology, New Delhi and later worked as a Pool-Officer of Council of Scientific and Industrial Research, New Delhi. Earlier, he taught at Budha Institute of Technology and Science Research College, Jodhpur and Government Bangor PG College, Pali, Rajasthan and subsequently served as an Associate Professor and Head, Department of Microbiology, Maharaja Ganga Singh University, Bikaner, Rajasthan. Dr. Gehlot worked out three major research projects sponsored by UGC, DST and CSIR, New Delhi. He has published more than 80 research papers, book chapters and review articles in journals of international and national repute and has edited three book entitled “Pyrenomycetes Fungi”, “Arbuscular Mycorrhizal Fungi” and “Microbes: In Action” published by AgroBios, India and “Fungi and their Role in Sustainable Development: Current Perspectives” published by Springer International. He attended several International and National Seminars, Symposia, Conferences and chaired technical sessions and presented papers in some of them. He is an active member Mycological Society of India, Society of Mycology and Plant Pathology, India, Association of Microbiologists of India, Indian Science Congress Association, etc.

Affiliations and expertise

Associate Professor, Department of Botany, Jai Narain Vyas University Jodhpur, India

Life Sciences

Physical Sciences & Engineering

Social Sciences & Humanities

Health