
Neuroscience for Addiction Medicine: From Prevention to Rehabilitation - Constructs and Drugs
- 1st Edition, Volume 223 - January 14, 2016
- Imprint: Elsevier
- Editors: Hamed Ekhtiari, Martin Paulus
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 4 - 6 3 5 4 5 - 7
- eBook ISBN:9 7 8 - 0 - 4 4 4 - 6 3 5 4 4 - 0
Neuroscience for Addiction Medicine: From Prevention to Rehabilitation: Constructs and Drugs is the latest volume from Progress in Brain Research focusing on new trends and devel… Read more

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Request a sales quoteNeuroscience for Addiction Medicine: From Prevention to Rehabilitation: Constructs and Drugs is the latest volume from Progress in Brain Research focusing on new trends and developments in addiction research. This established international series examines major areas of basic and clinical research within neuroscience, as well as popular emerging subfields such as addiction. This volume takes an integrated approach to review and summarize some of the most recent progress from the subfield of addiction research, with particular emphasis on potential applications in a clinical setting.
- Explores new trends and developments in basic and clinical research in the addiction subfield of neuroscience
- Uses an integrated approach to review and summarize recent progress
- Emphasizes potential applications in a clinical setting
- Enhances the literature of neuroscience by further expanding the established international series Progress in Brain Research
Part 1: Neuroscience Constructs for Addiction Medicine
Chapter 1: Neuroscience of resilience and vulnerability for addiction medicine: From genes to behavior
- Abstract
- 1 Behavioral Traits
- 2 Neurobiological Factors
- 3 Genetics
- 4 Epigenetics
- 5 Developmental Factors
- 6 Conclusion and Future Directions
Chapter 2: Drug-induced neurotoxicity in addiction medicine: From prevention to harm reduction
- Abstract
- 1 Introduction
- 2 Drug-Induced Neurotoxicity: Mechanisms and Pathways
- 3 Drug-Induced Neurotoxicity: Triggering and Susceptibility Factors
- 4 Drug-Induced Neurotoxicity: Potential Preventive Strategies
- 5 Drug-Induced Neurotoxicity in Addiction Medicine
- 6 Conclusion and Future Directions
- Acknowledgments
Chapter 3: Stress psychobiology in the context of addiction medicine: from drugs of abuse to behavioral addictions
- Abstract
- 1 Introduction
- 2 Stress Response Systems
- 3 Stress as a Vulnerability Factor for Initiation and Maintaining Substance Abuse
- 4 Stress as a Risk Factor for Relapse
- 5 Stress and Behavioral Addictions
- 6 Moderators of the Stress Effects on the Addiction Cycle
- 7 Discussion
- 8 Conclusion
Chapter 4: Reinforcement principles for addiction medicine; from recreational drug use to psychiatric disorder
- Abstract
- 1 Introduction
- 2 Positive and Negative Reinforcement
- 3 Secondary and Conditioned Reinforcement
- 4 Measuring Reinforcement in Animal Models
- 5 Drugs of Abuse and Emergent Withdrawal Symptoms as Reinforcers
- 6 Neuroadaptational Intersections of Reinforcement Processes in Addiction
- 7 Conclusion and Future Directions
- Acknowledgments
Chapter 5: Neuroscience of attentional processes for addiction medicine: from brain mechanisms to practical considerations
- Abstract
- 1 Introduction
- 2 Clinical Relevance of Attentional Bias: Is Attentional Bias and Artifact of Impaired Executive Control?
- 3 Attention Retraining: A Multimodal Activity
- 4 Attentional Bias: Therapeutic Implications
- 5 Pharmacological Interventions
- 6 Noninvasive Brain Stimulation
- 7 Conclusions and Future Directions
Chapter 6: Neuroscience of learning and memory for addiction medicine: from habit formation to memory reconsolidation
- Abstract
- 1 Introduction
- 2 Drug-induced Alterations to Learning and Memory
- 3 Learning and Memory Systems as Addiction Medicine
- 4 Special Considerations for Memory Manipulations in the Treatment of Addiction
- 5 Conclusions and Future Directions
Chapter 7: Neuroscience of drug craving for addiction medicine: From circuits to therapies
- Abstract
- 1 Introduction
- 2 Models of Drug Craving: From Behavioral to Cognitive Perspectives
- 3 Neurocognitive Basis of Drug Craving: Region-Based Perspective
- 4 Neurocognitive Basis of Drug Craving: Network-Based Perspective
- 5 Neurocognitive Model of Drug Craving as a Dynamic Process
- 6 Neurocognitive Interventions in Craving-Related Processes
- 7 Clinical Implications for an Integrative Neurocognitive Model of Craving
- 8 Conclusions and Future Directions
Chapter 8: Response inhibition and addiction medicine: from use to abstinence
- Abstract
- 1 Introduction
- 2 Response Inhibition Tasks
- 3 The Neurobiology of Control
- 4 Response Inhibition and Drugs of Abuse
- 5 Response Inhibition and Abstinence
- 6 Conclusion and Future Directions
Chapter 9: Neuroscience of inhibition for addiction medicine: from prediction of initiation to prediction of relapse
- Abstract
- 1 Introduction
- 2 Commonly Used Response Inhibition Tasks in Drug Addiction
- 3 Part 1: Progression into Addiction/Problematic Substance Use (Table 1)
- 4 Part 2: Prediction of Clinical Outcome in Already Addicted Individuals (Table 2)
- 5 Conclusion and Future Directions
- Acknowledgments
Part 2: Drugs and Behaviours for Addiction Medicine
Chapter 10: Neuroscience of nicotine for addiction medicine: novel targets for smoking cessation medications
- Abstract
- 1 Introduction
- 2 Phases of Nicotine Dependence
- 3 Neurocircuitry Underlying the Development of Nicotine Dependence
- 4 Neural Substrates Underlying Nicotine Dependence
- 5 Conclusion and Future Directions
- Acknowledgments
Chapter 11: Neuroscience of alcohol for addiction medicine: Neurobiological targets for prevention and intervention in adolescents
- Abstract
- 1 Introduction
- 2 Brain Volume
- 3 White Matter Microstructure
- 4 Brain Function
- 5 Conclusion and Future Directions
Chapter 12: Neuroscience of opiates for addiction medicine: From stress-responsive systems to behavior
- Abstract
- 1 Introduction
- 2 AVP and V1b Systems
- 3 Endogenous Opioid Systems
- 4 Orexin and Its Receptors
- 5 HPA Axis
- 6 Conclusion and Future Directions
Chapter 13: Opioid neuroscience for addiction medicine: From animal models to FDA approval for alcohol addiction
- Abstract
- 1 Introduction: The Role of Opioids in Alcohol Reward
- 2 Clinical Studies of Naltrexone in Alcoholism
- 3 A118G OPRM1 Mis-Sense Single-Nucleotide Polymorphism: Molecular and Cellular Effects
- 4 A118G OPRM1 Mis-Sense Single-Nucleotide Polymorphism: Animal Model Studies
- 5 A118G OPRM1 Mis-Sense Single-Nucleotide Polymorphism: Human Pharmacogenetic Studies of Alcohol
- 6 Pharmacogenetic Studies of Naltrexone Clinical Trials for Alcohol Addiction
- 7 Conclusion and Future Directions
Chapter 14: Competing neurobehavioral decision systems theory of cocaine addiction: From mechanisms to therapeutic opportunities
- Abstract
- 1 Introduction
- 2 The Competing Neurobehavioral Decision Systems Theory
- 3 The Competing Neurobehavioral Decisions Systems Theory and Cocaine
- 4 The CNDS and Cocaine Treatment
- 5 Conclusion and Future Directions
- Acknowledgments
Chapter 15: Clinical neuroscience of amphetamine-type stimulants: From basic science to treatment development
- Abstract
- 1 Introduction
- 2 Pharmacology and Neurotoxicity
- 3 Neurocognitive Effects
- 4 Treatment
- 5 Conclusion and Future Directions
Chapter 16: Behavioral addictions in addiction medicine: from mechanisms to practical considerations
- Abstract
- 1 Introduction
- 2 Gambling Disorder
- 3 Neural Features of Gambling Disorder
- 4 Genetics
- 5 Treatment of Gambling Disorder
- 6 Problematic Internet Use and IGD
- 7 Neural Features of PIU
- 8 Genetics
- 9 Treatment
- 10 Future Directions
- Acknowledgments
Chapter 17: Neural systems implicated in obesity as an addictive disorder: from biological to behavioral mechanisms
- Abstract
- 1 Introduction
- 2 Shared Neural Systems: Reward Dysfunction
- 3 Shared Neural Systems: Impulsivity
- 4 Shared Neural Systems: Emotion Dysregulation
- 5 Summary of Shared Neural Systems
- 6 Differences Between Obesity and Addictive Disorders
- 7 Differences Between Addictive Disorders
- 8 Future Directions in Food Addiction Research
- 9 Concluding Remarks
- Acknowledgments
- Edition: 1
- Volume: 223
- Published: January 14, 2016
- No. of pages (Hardback): 348
- No. of pages (eBook): 348
- Imprint: Elsevier
- Language: English
- Hardback ISBN: 9780444635457
- eBook ISBN: 9780444635440
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Hamed Ekhtiari
MP