
Natural Polymers in Wound Healing and Repair
From Basic Concepts to Emerging Trends
- 1st Edition - June 23, 2022
- Imprint: Elsevier
- Editors: Mahesh K. Sah, Naresh Kasoju, Joao F. Mano
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 9 0 5 1 4 - 5
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 0 5 1 5 - 2
Natural Polymers in Wound Healing and Repair: From Basic Concepts to Emerging Trends presents comprehensive coverage on the development and application of natural polymers… Read more

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Request a sales quoteNatural Polymers in Wound Healing and Repair: From Basic Concepts to Emerging Trends presents comprehensive coverage on the development and application of natural polymers in wound healing and repair, including fundamental concepts, traditional approaches, cutting-edge methods and emerging trends. The application of natural polymers has evolved from their use in the simplest wound management material, to drug eluting matrices, to cell-laden constructs, and to 3D bio-printed skin equivalents. This book reflects the remarkable progress that has been made in recent years in this innovative field.
This is an essential resource for researchers, scientists, and advanced students across polymer science, biomaterials, bio-based and sustainable materials, biomedicine, biomedical engineering, pharmaceuticals, and materials science and engineering. It will also be valuable to R&D professionals, scientists, technologists and all those working in a medical setting who are interested in the latest developments in advanced materials for wound management, healing and repair.
- Provides up-to-date coverage of natural polymer-based biomaterials in wound healing and repair, covering sources, processing and properties
- Describes cellular and molecular events in wound healing
- Introduces conventional and advanced methodologies for wound management
- Offers a comprehensive understanding of state-of-the-art and emerging concepts in wound healing, including drug-eluting matrices, cell-laden systems and personalized bio-fabrication strategies
- Cover image
- Title page
- Table of Contents
- Copyright
- List of contributors
- About the editors
- Preface
- Introduction
- Chapter 1. Fundamentals of skin wound healing and repair: A brief review on cellular and molecular pathophysiologic basis of wound healing
- Abstract
- Chapter Outline
- 1.1 Introduction
- 1.2 Roles of epidermal T cells during tissue repair
- 1.3 Other possible abnormal (pathological) tissue repair processes that frequently occur and are clinically relevant
- 1.4 Few basic experimental methods used for investigating the pathophysiology of wound healing
- 1.5 What the future holds in the experimental pathophysiology of skin wound healing
- 1.6 Concluding remarks
- Acknowledgment and dedication
- References
- Chapter 2. Traditional and advanced wound dressings: physical characterization and desirable properties for wound healing
- Abstract
- Chapter Outline
- 2.1 Introduction
- 2.2 Traditional and advanced wound dressings
- 2.3 Physical characterization of wound dressings
- 2.4 Ideal properties for the wound dressings
- 2.5 Conclusion
- References
- Chapter 3. Natural-based biomaterials for drug delivery wound healing patches
- Abstract
- Chapter Outline
- 3.1 Introduction
- 3.2 Transdermal drug delivery patches
- 3.3 Hydrogels versus nonhydrogels polymeric patches
- 3.4 Patches based on biopolymers
- 3.5 Conclusions
- References
- Chapter 4. Controlled drug delivery system for wound healing: formulations and delivery required therapeutic agents
- Abstract
- Chapter Outline
- 4.1 Introduction
- 4.2 Routes of delivery for wound healing
- 4.3 Route-specific drug delivery mechanisms
- 4.4 Drug delivery mediums
- 4.5 Therapeutic agents for wound healing
- 4.6 Conclusion
- References
- Chapter 5. Artificial skin: current advanced methods of fabrication and development
- Abstract
- Chapter Outline
- 5.1 Introduction
- 5.2 Why do we need alternatives to the skin graft?
- 5.3 Advanced tissue engineering approaches to regenerate skin
- 5.4 Modification of polymers for fabrication of artificial skin
- 5.5 Modern tissue engineering approaches to regenerate skin
- 5.6 Animal models to test tissue engineered fabricated skin
- 5.7 Current commercially available skin grafts in market
- 5.8 Advantages and disadvantages of artificially fabricated skin
- 5.9 Development of current fabrication technologies of artificial skin
- 5.10 Conclusion
- References
- Chapter 6. Natural polymer based hydrogel systems for wound management
- Abstract
- Chapter Outline
- 6.1 Introduction
- 6.2 Polysaccharide biomaterials for wound dressing
- 6.3 Protein biomaterials for wound dressing
- 6.4 Conclusion
- References
- Chapter 7. Natural polymer based electrospun systems for wound management
- Abstract
- Chapter Outline
- 7.1 Introduction
- 7.2 Fabrication of electrospun system for wound healing
- 7.3 Natural polymers–based electrospun system for wound management
- 7.4 Important natural polymers for nanofibrous system for wound healing
- 7.5 Commercially available natural polymer–based electrospun systems for wound management
- 7.6 Conclusions and future prospects
- Abbreviations
- References
- Chapter 8. Three-dimensional bioprinting of skin tissue equivalents using natural polymers as bioinks for potential applications in wound repair
- Abstract
- Chapter Outline
- 8.1 Introduction
- 8.2 Skin physiology and pathophysiology
- 8.3 Regenerative strategies for skin wound healing and repair
- 8.4 Three-dimensional bioprinting for biofabrication of skin constructs
- 8.5 Bioinks for three-dimensional bioprinting of skin tissue equivalents
- 8.6 Summary, challenges, and prospects
- Acknowledgments
- References
- Chapter 9. Blood-derived products in wound healing and repair
- Abstract
- Chapter Outline
- 9.1 Introduction
- 9.2 Wound healing process and role of blood components
- 9.3 Blood components, preparation, and translational potential
- 9.4 Summary and conclusion
- Acknowledgments
- References
- Chapter 10. Natural antimicrobial and bioactive agents as additives in wound dressings
- Abstract
- Chapter Outline
- 10.1 Introduction
- 10.2 Modern wound dressing
- 10.3 Bioactive wound dressing
- 10.4 Wound infections and natural antimicrobials
- 10.5 Requirement of antimicrobial wound dressing
- 10.6 Conclusion
- References
- Chapter 11. Curcumin-based strategies in wound healing and skin tissue regeneration
- Abstract
- Chapter Outline
- 11.1 Introduction: wounds and healing process
- 11.2 Wound healing efficacy of curcumin
- 11.3 Limitations in the use of CUR and recent adaptations
- 11.4 Wound healing efficacy of CUR-based nanoformulations
- 11.5 Summary and conclusion
- Acknowledgment
- Conflict of interest
- References
- Chapter 12. Collagen-based strategies in wound healing and skin tissue engineering
- Abstract
- Chapter Outline
- 12.1 Introduction
- 12.2 History of collagen in biomedical use
- 12.3 Collagen types
- 12.4 Sources of collagen
- 12.5 Things to know before collagen extraction and use
- 12.6 General procedure for type I collagen extraction
- 12.7 Reconstitution of collagen
- 12.8 Collagen cross-linking
- 12.9 Sterilization methods
- 12.10 Role of collagen in wound healing
- 12.11 Application of collagen in wound healing
- 12.12 Collagen in skin tissue engineering
- 12.13 Conclusion and remarks
- References
- Chapter 13. Silk fibroin and silk sericin in skin tissue engineering and wound healing: retrospect and prospects
- Abstract
- Chapter Outline
- 13.1 Introduction
- 13.2 Skin physiology
- 13.3 Skin pathophysiology and wound healing
- 13.4 Silk biomaterials
- 13.5 Silk fibroin in skin tissue engineering and wound healing
- 13.6 Silk sericin in skin tissue engineering and wound healing
- 13.7 Molecular insights into silk biomaterials in a wound healing context
- 13.8 Trends in clinical investigations and commercialization of silk-based wound healing biomaterials
- 13.9 Summary, challenges, and prospects
- Acknowledgment
- References
- Chapter 14. Chitin- and chitosan-based strategies in wound healing
- Abstract
- Chapter Outline
- 14.1 Introduction
- 14.2 Chitin
- 14.3 Chitosan
- 14.4 Application of chitin and chitosan as wound dressings
- 14.5 Conclusion
- Acknowledgments
- References
- Acronyms
- Chapter 15. Alginate-based wound dressings for skin healing and regeneration
- Abstract
- Chapter Outline
- 15.1 Introduction
- 15.2 Alginate properties and commercially available alginate wound dressings
- 15.3 Alginate-based wound dressings
- 15.4 Alginate-based hydrogels in skin regeneration
- 15.5 Conclusion
- Acknowledgment
- References
- Chapter 16. Eggshell membrane in skin tissue engineering and wound healing
- Abstract
- Chapter Outline
- 16.1 Introduction
- 16.2 Eggshell membrane and its processed forms
- 16.3 Eggshell membrane in wound healing and skin tissue engineering
- 16.4 Conclusions and future perspectives
- Acknowledgment
- Conflict of interest
- Abbreviations
- References
- Chapter 17. Decellularized extracellular matrices–based strategies in wound healing and skin tissue engineering
- Abstract
- Chapter Outline
- 17.1 Introduction
- 17.2 Tissue engineering approach to repair skin defects
- 17.3 Extracellular matrix-based biomaterials and substitutes: wound healing and skin regeneration
- 17.4 Translational challenges associated with decellularized matrices
- References
- Chapter 18. Innovative approaches and future perspectives of natural polymers in wound healing and repair
- Abstract
- Chapter Outline
- 18.1 Introduction
- 18.2 Electrospinning in advanced wound care
- 18.3 Three-dimensional printing in advanced wound care
- 18.4 Artificial skin and latest advances
- 18.5 Personalized wound care products
- 18.6 Challenges and future perspectives
- Acknowledgment
- References
- Index
- Edition: 1
- Published: June 23, 2022
- No. of pages (Paperback): 498
- No. of pages (eBook): 498
- Imprint: Elsevier
- Language: English
- Paperback ISBN: 9780323905145
- eBook ISBN: 9780323905152
MS
Mahesh K. Sah
NK
Naresh Kasoju
JM