Nanotechnology-Based Sensing Platforms for Illicit Drugs
- 1st Edition - April 11, 2025
- Imprint: Elsevier
- Editors: Sayan Ganguly, Poushali Das, Amin Reza Rajabzadeh, Seshasai Srinivasan
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 2 3 7 4 0 - 9
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 3 7 4 1 - 6
Nanotechnology-Based Sensing Platforms for Illicit Drugs reviews different types of sensors that detect illicit drugs, with a special focus on the advantages provided by incorpora… Read more
Purchase options
Institutional subscription on ScienceDirect
Request a sales quoteNanotechnology-Based Sensing Platforms for Illicit Drugs reviews different types of sensors that detect illicit drugs, with a special focus on the advantages provided by incorporating nanotechnology in their design. The book starts with the fundamentals, classification, progress, the current state of research on nanotechnology-based sensors, and an overview of materials commonly used. Subsequent chapters focus on the chemical interactive behaviors of drugs and their detection methods. It includes a thorough discussion on the design, fabrication, and characterization of sensors for illicit drug detection. Final sections provide an overall outlook on recent technological advances in drug detection devices and future research.
This book is a valuable resource for researchers, scientists, and professionals interested in biosensors, nanotechnology, and their applications in illicit drug detection.
- Reviews cutting-edge research in the fabrication, characterization, properties, and application of sensors for illicit drugs
- Presents a wide range of applications for nanomaterials in sensor-based technologies
- Highlights sensing mechanisms and their behavior against different molecules
Advanced students and researchers interested in biosensors, nanotechnology, and their application to illicit drug detection, Scientists and engineers, from both academia and industry, working on developing diagnostics to support illicit drug testing
- Title of Book
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Chapter 1. General introduction to nanotechnology-based sensors
- Introduction
- Classification of nanosensors
- Surface modifications and nanosensors functionalization
- Nanosensors and their applications
- Optical nanosensors
- Fluorescent nanosenors
- Mechanical nanosensors
- Magnetic nanosensors
- Conclusions
- Chapter 2. Classical materials for sensors
- Introduction
- Applications of nanotechnology in detection of drugs
- Nanosensors and their working principle
- Colorimetric
- Surface-enhanced Raman spectroscopy
- Electrochemiluminescence
- Electrochemical
- Materials used as drug detection sensors
- Carbon-based material for drug detection
- Aptamers
- Metal nanoparticles
- Polymer materials
- Role of artificial intelligence in drug sensing
- Machine learning
- Deep learning
- Generative AI
- Conclusion
- Chapter 3. Chemical interactive behaviors of drugs
- Introduction
- Drug–receptor interactions
- Pharmacokinetics and drug interactive behavior
- Chemical interactions
- Polymer–drug interactions
- Quantum dots–drug interactions
- Conclusions
- AI disclosure
- Chapter 4. Drug detection methods
- Introduction
- Prevalent varieties of substances used for drug-facilitated sexual assault
- Alcohol
- Cannabis
- Cocaine
- Heroin
- MDMA (Ecstasy)
- Methamphetamine
- Rohypnol (flunitrazepam)
- Fentanyl
- Conventional techniques for detecting illicit drugs
- Detection windows
- Ultraviolet spectroscopy
- Thin-layer chromatography
- Immunoassay
- Mass spectrometry (MS)
- Summary
- Chapter 5. Design and fabrication strategies for drugs and biological sensors
- Introduction
- Overview on biosensors and nanosensors for drug detection
- Basic design and skeletal components of a sensor device
- Ideal materials and considerations for sensor fabrication
- Nanomaterials for enhanced sensitivity
- Biocompatible materials for in vivo applications
- Integration of molecularly imprinted polymers
- Considerations for wearable sensor design
- Materials for implantable sensors
- Smart materials for real-time monitoring
- Quantum materials and the way ahead
- Types of sensors and fabrication process
- Optical sensors
- Electrochemical sensors
- Piezoelectric sensors
- Challenges associated with the designing and fabrication of sensors
- Future perspectives for improvement in sensing technologies
- Conclusions
- Chapter 6. Characterization of various sensors
- Introduction
- Essential sensors for everyday activities
- Optical characterization methods
- Electrical characterization methods
- Thermal characterization methods
- Mechanical characterization methods
- Potential for future development and expansion
- Conclusions
- Chapter 7. Electrochemical detection of illicit drugs
- Introduction
- Electrochemical behavior of illicit drugs
- Synthesis and properties of nanomaterials-based composite for electrochemical sensors
- Nanoparticles-based composite
- Carbonaceous nanomaterials-based composite
- Nanofilms-based composite
- Application of nanomaterials composites-based electrochemical sensors for detection of illicit drugs
- Carbonaceous nanostructures-based sensor
- Metal/metal oxide nanomaterials-based sensors
- Polymer composites-based sensor
- Summary
- Chapter 8. Colorimetric sensors for illicit drug detection
- Introduction
- Illicit drugs—What are they?
- A brief explanation on chemical sensors
- Nanomaterials-based colorimetric detection of illicit drugs
- Colorimetric detection design based on lateral flow assay system
- Colorimetric detection design based on smartphone/mobile phones attached RGB system
- Colorimetric detection design based on microfluidic system
- Colorimetric detection design based on solution system
- Colorimetric detection design based on solid supports system
- Colorimetric detection design based on enzyme mimetic (peroxidase) system
- Common recognition materials applied in colorimetric detection fabrication
- Aptamers as biological recognition material
- Antibodies as biological recognition material
- Enzymes as biological recognition material
- Other biological recognition materials
- Colorimetry combined with fluorescence-based detection of illicit drugs
- Colorimetric detection of illicit drugs based on organic/inorganic chromophores
- Summary and outlooks
- Chapter 9. Fluorescence-based sensors for detection of illicit drugs
- Introduction
- Principle
- Advantages of using fluorescence-based sensors for detection
- Specific sensor types in fluorescence-based detection of illicit drugs
- Working principle
- Applications
- Critical analysis
- Molecularly imprinted polymers (MIPs) in fluorescence-based detection of illicit drugs
- Working principle
- Applications
- Critical analysis
- Quantum dots: Illuminating multiplicity in illicit drug detection
- Working principles
- Applications
- Critical analysis
- Comparative analysis of fluorescence-based sensors and conventional techniques
- Fluorescence-based sensors
- Mass spectrometry
- Nuclear magnetic resonance
- Raman spectroscopy
- Capillary electrophoresis
- Gas chromatography
- Liquid chromatography
- Breath test
- Blood test
- Urine test
- Saliva test
- Hair test
- Emerging trends and innovations in the detection of illicit drugs
- Regulatory and ethical considerations in the utilization of fluorescence-based sensors for drug detection
- Conclusion
- Chapter 10. Surface-enhanced Raman spectroscopy for detection of illicit drugs
- Introduction
- SERS-based detection of illicit drugs in biological fluid
- SERS-based detection of illicit drugs in wastewater
- Microfluidic integrated SERS platforms
- Conclusion and future perspective
- Chapter 11. Chromatography for detection of illicit drugs
- Introduction
- Primary ideas of chromatography on bioanalysis
- Applications
- Conclusions and future outlook
- Chapter 12. Devices used in the detection of illicit drugs
- Introduction
- Transformative role of portable sensor technologies
- The impact of portable sensor technologies in forensic toxicology
- Advancements in criminal investigations and public health
- Extending the reach and accessibility of forensic toxicology
- Worldwide impact of illicit drug use
- Rapid proliferation of illicit drugs
- Indirect consequences of drug abuse
- Collaborative approach to addressing illicit drug use
- Addressing the global impact of illicit drug use
- Evolving drug landscape in Europe
- Challenge of polydrug consumption
- Need for advancements in detection techniques
- Significance of biosensors in scientific and technical research
- Role of biosensors in addressing contemporary challenges
- Diverse types of biosensors
- Critical role of biosensors in scientific and technical advancements
- Electrochemical biosensors
- Impact and significance in various fields (Kroning and Wang, 2021)
- Specific applications and advantages (Zheng et al., 2013)
- Application of electrochemical sensors
- Fourier transform infrared spectroscopy
- Advantages and challenges of electrochemical sensors
- The global issue of illicit drug trade
- Consequences of illicit drug production and trafficking
- Negative health outcomes and policy responses
- Addressing the complexities of the illicit drug trade
- Impact of the pandemic on drug trafficking
- Comprehensive overview of illicit drugs and drug trafficking
- Effects on aquatic environment
- Importance of monitoring
- Challenges and urgent need for alternative detection tools
- Potential of sensor-based methods for detecting illicit drugs
- Sensor-based detection tools
- Importance of detecting illicit drugs in water samples
- Optical sensors for illicit drug detection
- Significance and categorization of detection methods
- Chapter 13. Rapid detection of illicit drugs in saliva
- Introduction
- Scope of study
- Sources of saliva in forensic investigation
- Use of saliva in various drugs detection
- Types of illicit drugs
- Challenges in rapid detection
- Collection techniques of saliva
- Storage and extraction of samples
- Detection techniques
- Chromatographic techniques
- Liquid chromatography–mass spectrometry (Case study-1)
- Gas chromatography–mass spectrometry (Case study-2)
- Spectroscopic techniques
- Infrared spectroscopy (IR)
- Ultraviolet spectroscopy (UV)
- Raman spectroscopy
- Microfluidics
- Quality assurance of drug testing
- Conclusion
- Chapter 14. Advantages of point-of-care detections
- Introduction
- Enhanced patient care and outcomes
- Rapid diagnostics
- Personalized treatment
- Remote monitoring
- Operational efficiency and cost savings
- Streamlined workflows
- Bedside decision-making
- Resource conservation
- Cost savings
- Improved infection control and public health
- Reduced transmission risk
- Outbreak management
- Surveillance and monitoring
- Conclusion
- Chapter 15. Commercially adoptable nanotechnology platform for illicit drug sensing
- Introduction
- Different types of nanoparticles in illicit drug sensing
- Gold nanoparticles as sensing probe
- Carbon nanotubes (CNTs) as sensing probe
- Graphene as sensing probe
- Summary and outlook
- Chapter 16. Challenges and future perspective of illicit drug sensors and strategies
- Introduction
- Brief background on current technologies and strategies
- Sensitivity and selectivity
- Exploring the difficulties in distinguishing between chemically analogous illicit substances
- Importance of high sensitivity and selectivity in sensor development
- Real-time detection
- Blockchain technology
- Blockchain for secure and transparent data management in drug detection
- Illicit drug detection methods and artificial intelligence
- Summary of challenges and current limitations
- Index
- Edition: 1
- Published: April 11, 2025
- Imprint: Elsevier
- No. of pages: 450
- Language: English
- Paperback ISBN: 9780443237409
- eBook ISBN: 9780443237416
SG
Sayan Ganguly
Sayan Ganguly is a researcher at the University of Waterloo, Canada. His primary research interests include superabsorbent hydrogels, polymer-graphene nanocomposites, MXene-polymer systems, 3D printing, polymer composites for EMI shielding, and conducting polymer composites.
Affiliations and expertise
Senior Postdoctoral Researcher, University of Waterloo, CanadaPD
Poushali Das
Poushali Das is a senior postdoctoral research fellow at McMaster University's Faculty of Engineering, Hamilton, Canada. Her research interests include multifunctional luminescent quantum dots and their applications in sensors, antioxidant properties, and the biomedical field, polymer–quantum dot nanocomposites, MXene–polymer nanocomposites, and sonochemical synthesis of nanocomposites.
Affiliations and expertise
Senior Postdoctoral Research Fellow, McMaster University, CanadaAR
Amin Reza Rajabzadeh
Dr. Amin Reza Rajabzadeh is an Associate Professor and former Chair of the Biotechnology Program at the School of Engineering Practice and Technology, McMaster University, Canada. Dr. Rajabzadeh specializes in the field of biochemical engineering with a focus on biosensors, bioseparation and purification, bioprocess monitoring and control, bioreactor design, and environmental engineering. Dr. Rajabzadeh is a Professional Engineer of Ontario and is a member of the Canadian Engineering Education Association and the American Society for Engineering Education. Dr. Rajab Zadeh was a MacPherson Leadership in Teaching and Learning (LTL) Fellow from 2017 to 2019.
Affiliations and expertise
Associate Professor, McMaster University, CanadaSS
Seshasai Srinivasan
Dr. Seshasai Srinivasan is an Associate Professor in McMaster University's Faculty of Engineering. Prior to this, he has held a Research Scientist and a part-time instructor position in the Department of Mechanical and Industrial Engineering of Ryerson University, a postdoctoral position at the Laboratory of Food Process Engineering of the Swiss Federal Institute of Technology (ETH-Zurich) in Switzerland and a Research Associate position in the Engine Research Center of the University of Wisconsin-Madison.
Affiliations and expertise
Associate Professor, McMaster University, CanadaRead Nanotechnology-Based Sensing Platforms for Illicit Drugs on ScienceDirect