Nanostructures for Novel Therapy

Chapter 1: Novel approaches for preparation of nanoparticles

• Abstract
• 1. Introduction
• 2. Synthetic Methods for Preparation of Metal Nanoparticles
• 3. Application of Metal Nanoparticles in Theranostics
• 4. Conclusions
• Acknowledgments

Chapter 2: Applications of nanoscale drugs carriers in the treatment of chronic diseases

• Abstract
• 1. Introduction in Drug Delivery and Targeting
• 2. Applications of Nanotechnology in Drug Delivery and Targeting
• 3. Conclusions

Chapter 3: Functionalization of nanoparticles in specific targeting and mechanism release

• Abstract
• 1. Introduction
• 2. Controlled-Release Mechanisms
• 3. Project of Nanoparticles
• 4. Nanoparticles Targeting
• 5. Conclusions

Chapter 4: Fabrication and characterization of natural/synthesized, micro-, and nanostructured materials for biomedical applications

• Abstract
• 1. Introduction
• 2. Pearl Shell
• 3. Microstructure Analysis of Nacre by Transmission Electron Microscopy
• 4. Micro-/Nanoparticles
• 5. Surface Modification of Nanoparticles
• 6. 2D Periodic Structure by Thermal Imprinting Process
• 7. Functionalities for Biomedical Applications
• 8. Summary and Future Directions

Chapter 5: Multifunctional nanostructured biopolymeric materials for therapeutic applications

• Abstract
• 1. Introduction
• 2. Biopolymers
• 3. Multifunctional Nanostructured Materials
• 4. Therapeutic Applications
• 5. Conclusions and Perspectives

Chapter 6: Polymeric pharmaceutical nanoparticles developed by electrospray

• Abstract
• 1. Introduction
• 2. Polymeric Particles and Atomizers
• 3. Electrospray
• 4. Therapeutic Nanoparticles Loaded by Electrospray
• 5. Conclusions

Chapter 7: Nanoformulation and administration of PUFA-rich systems for applications in modern healthcare

• Abstract
• 1. Introduction
• 2. Lipid Nanoparticles: Types and Fabrication Technology
• 3. Understanding the Physiological System for Therapy: The Significance of Lipid Nanotechnology at Tissue and Cellular Level
• 4. Therapeutic Lipid Nanostructures
• 5. Risk and Hazard Assessment
• 6. Challenges and Scope
• 7. Conclusions
• Acknowledgments

Chapter 8: Electrospinning and surface modification methods for functionalized cell scaffolds

• Abstract
• 1. Electrospinning for Tissue Engineering
• 2. Fundamentals of the Electrospinning Process
• 3. Tuning the Morphology of Electrospun Scaffolds and its Effects on Cell Behavior
• 4. Surface Modification Methods of Electrospun Nanofibers
• 5. Conclusions

Chapter 9: Short peptide self-assembled nanostructures for therapeutics innovative delivery

• Abstract
• 1. Introduction
• 2. Preparation and Characterization of Self-Assembling Short Peptides
• 3. Drug-Delivery Applications
• 4. Self-Assembly to Achieve a Therapeutic Effect
• 5. Conclusions and Future Outlook
• Abbreviations

Chapter 10: Peptoids: tomorrow’s therapeutics

• Abstract
• 1. Introduction
• 2. Peptoid Synthesis
• 3. Peptoid Structures
• 4. Applications of Peptoids
• 5. Conclusions

Chapter 11: Electrospinning of collagen nanofiber scaffolds for tissue repair and regeneration

• Abstract
• 1. Introduction
• 2. Tissue Engineering
• 3. Scaffold
• 4. Nanofibers
• 5. Electrospinning
• 6. Applications of Electrospun Collagen

Chapter 12: Nanostructured therapeutic systems with bioadhesive and thermoresponsive properties

• Abstract
• 1. Introduction
• 2. Bioadhesive Systems
• 3. Stimuli-Responsive Polymers
• 4. Hydrogels
• 5. Mucoadhesive Thermoresponsive Systems
• 6. Characterization of Mucoadhesive Thermoresponsive Systems
• 7. Conclusions

Chapter 13: Design considerations in the development of wound healing bionanomaterials

• Abstract
• 1. Introduction
• 2. Skin: Properties, Growth, and Regeneration
• 3. Bionanomaterials
• 4. Nanostructures
• 5. Nanofabrication
• 6. Conclusions

Chapter 14: Role of nanostructure molecules in enhancing the bioavailability of oral drugs

• Abstract
• 1. Nanotechnology: Some Basic Concepts
• 2. Nanostructure Molecules or Nanoparticles
• 3. Absorption of Oral Drugs in the Gastrointenstinal Tract
• 4. Nanoscience and Nanotechnology: From Basic Science to Applications

Chapter 15: Improvement steps of plastic surgery to tissue engineering by nanotechnology

• Abstract
• 1. Introduction
• 2. Development of Nanotechnology Into Nanomedicine
• 3. Nanomaterials Used in Medical Therapeutics
• 4. Nanotechnology in Diagnostics
• 5. Nanotechnology and Drug Delivery
• 6. Use of Nanotechnology in Tissue Engineering
• 7. Conclusions

Chapter 16: Dendrimers and dendronized materials as nanocarriers

• Abstract
• 1. Introduction
• 2. Synthetic Approach
• 3. Physico-Chemical Properties of Dendritic Molecules useful for Nanocarriers
• 4. Drug–Dendritic Polymer Interactions
• 5. Types of Targeting by Nanodelivery System
• 6. Routes of Administration of Dendritic Molecules
• 7. Successful Examples of Dendritic Molecules as Nanocarriers
• 8. Conclusions
• Acknowledgments

Chapter 17: Gold nanostructures: preparation, properties, application in SERS, and biophotonics

• Abstract
• 1. Introduction
• 2. Experimental
• 3. Theoretical
• 4. Methods for Preparation of Gold Nanoparticles and Nanostructures. Application in SERS
• 5. Application of Au Nanostructures in Biophotonics
• 6. Conclusions
• Acknowledgments

Chapter 18: Quantum dots for bioimaging and therapeutic applications

• Abstract
• 1. Introduction
• 2. QDs for Bioimaging Applications
• 3. QDs for Therapy
• 4. Conclusions

Chapter 19: Lipid-based synthetic gene carriers

• Abstract
• 1. Introduction
• 2. Equilibrium Lipoplex Structure on the Nanoscale
• 3. The Kinetics of Lipoplex Formation
• 4. Discussion
• 5. Conclusions
• Conflict of Interests

Chapter 20: Using microsensors to promote the development of innovative therapeutic nanostructures

• Abstract
• 1. Introduction
• 2. Nano-Objects Definition and Properties
• 3. Integrated Analyte Handling
• 4. Measurements Techniques
• 5. Conclusions

Chapter 21: The effect of nanostructured surfaces on stem cell fate

• Abstract
• 1. Introduction
• 2. Nanostructured Surfaces
• 3. Stem Cells within the Human Body and Their Use in Regenerative Medicine
• 4. Interactions of Nanostructured Surfaces and Stem Cells
• 5. Future Perspective
• Acknowledgments

Chapter 22: Applications of aptamers for the diagnosis and therapy of different diseases

• Abstract
• 1. Introduction
• 2. Selection of Aptamers
• 3. Aptamers as Therapeutics
• 4. Challenges of Aptamers
• 5. Nanotechnology and Aptamers
• 6. Conclusions

Chapter 23: Recent progress in therapeutic diagnosis using photonic crystal nanostructures

• Abstract
• 1. Introduction to Photonic Crystal Nanostructures
• 2. Origin of Photonic Bandgap
• 3. Photonic Crystal Slabs
• 4. Materials and Fabrication Methods
• 5. Introduction to Biosensors
• 6. PC Laser Biosensors and Lab-on-Chip Devices
• 7. Conclusions

Chapter 24: Novel carriers and approaches: insight for psoriasis management

• Abstract
• 1. Introduction
• 2. Types of Psoriasis
• 3. Pathogenesis of Psoriasis
• 4. Function of Cytokines
• 5. Treatment Approaches for Psoriasis
• 6. Novel Colloidal Carriers for Psoriasis Treatment
• 7. Lipid-Based Particulate Carriers
• 8. Emulsion-Based Carriers
• 9. Conclusions

Chapter 25: Use of nanostructures based on noble metals in nanobiomedicine

• Abstract
• 1. Introduction
• 2. Optical Properties of Metal Nanostructures
• 3. Applications in Biological Systems and Biomedicine
• 4. Summary

Chapter 26: Innovative nonviral vectors for small-interfering RNA delivery and therapy

• Abstract
• 1. Introduction
• 2. Obstacles to In Vivo siRNA Delivery: The Biological Barriers and the Immunological Response
• 3. Chemical Modifications of siRNA
• 4. siRNA Delivery Systems: Focus on Liposomes and Lipoplexes
• 5. Clinical Trials
• 6. Conclusions

Chapter 27: siRNA-based nucleoceuticals for tissue regeneration

• Abstract
• 1. Introduction
• 2. Heart Regeneration
• 3. Kidney Regeneration
• 4. Liver Regeneration
• 5. Ocular Regeneration
• 6. Peritoneal Fibrosis Regeneration
• 7. Cartilage Regeneration
• 8. Skin Regeneration
• 9. Bone Regeneration
• 10. Nerve Regeneration
• 11. Conclusions

Chapter 28: Bone tissue regenerative medicine via bioactive nanomaterials

• Abstract
• 1. Introduction
• 2. Synthetic Approaches for Bone Tissue Replacement
• 3. Nanomaterials as key Enablers of Bone Regeneration
• 4. Risks and Obstacles of Nanomaterials Applications
• 5. Perspectives and Outlooks
• Acknowledgments

Chapter 29: Toxicity of nanostructures—a general approach

• Abstract
• 1. Introduction
• 2. Metallic Nanostructures
• 3. Nonmetallic Nanostructures
• 4. Conclusions

Chapter 30: Role of Excipients in formulation development and biocompatibility of lipid nanoparticles (SLNs/NLCs)

• Abstract
• 1. Introduction
• 2. Role of Excipients in SLNs and NLCs
• 3. Conclusions
• Acknowledgment