Nanostructured Materials for Biomedical Applications
- 1st Edition - June 18, 2024
- Imprint: Elsevier
- Editors: Raji Vijayamma, Nandakumar Kalarikkal, Sabu Thomas
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 9 0 8 3 8 - 2
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 0 8 3 9 - 9
Nanostructured Materials for Biomedical Applications highlights progress, challenges and opportunities in nanomedicine and discusses novel engineering approaches of nanost… Read more
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Request a sales quoteNanostructured Materials for Biomedical Applications highlights progress, challenges and opportunities in nanomedicine and discusses novel engineering approaches of nanostructured materials that are useful in various biomedical applications. The book provides a comprehensive review of the state-of-the-art in bio-nanotechnology, with an emphasis on diverse biomedical applications, such as in drug delivery, bioimaging, hyperthermia and targeted cancer therapy. Users will find this to be a broad introductory reference for anyone new to the field or those who wish to gain a thorough overview of nanostructured materials in the context of biomedical applications.
The breadth of this book will appeal to an interdisciplinary audience, including materials scientists, pharmaceutical scientists and biomedical engineers.
The breadth of this book will appeal to an interdisciplinary audience, including materials scientists, pharmaceutical scientists and biomedical engineers.
- Covers a range of nanomaterial types, including metal nanoparticles, luminescent nanoparticles, cubosomes, smart nanostructures, and much more
- Reviews the diverse applications of nanomaterials in biomedicine, such as in theranostics, biosensing, cancer therapy, drug delivery and tissue engineering
- Provides a concise, introductory reference for those new to the fields of bionanomaterials and bio-nanotechnology
Materials scientists and biomedical engineers, Pharmaceutical scientists, polymer scientists
- Cover image
- Title page
- Table of Contents
- Copyright
- List of contributors
- Chapter 1. Introduction to the synthesis and characterization of nanostructured materials
- Abstract
- 1.1 Synthesis and characterization of nanostructured materials
- 1.2 Conclusion and the probable future trends of nanostructured materials
- References
- Chapter 2. Metal and metal oxide nanoparticles—applications in medicine
- Abstract
- 2.1 Introduction
- 2.2 Metallic and metal oxide nanoparticles obtaining and physicochemical characterization
- 2.3 Metallic and metal oxide nanoparticles’ applications in medicine
- 2.4 Nanotoxicology for metallic and metal oxide nanoparticles
- References
- Chapter 3. MOF based nanostructures for light mediated cancer therapy
- Abstract
- 3.1 Introduction
- 3.2 Targeted drug delivery systems
- 3.3 Photothermal therapy using metal nanoparticles
- Acknowledgments
- References
- Chapter 4. Biological interactions and fate of nanomaterials in living systems
- Abstract
- 4.1 Introduction
- 4.2 Interactions of nanomaterials in the living system
- 4.3 Interactions between nanomaterials and cells
- 4.4 Fate of nanomaterials
- 4.5 Conclusion
- References
- Chapter 5. Cubosomes – excellent pharmaceutical carriers
- Abstract
- 5.1 Cubosomes
- 5.2 Structural components
- 5.3 Types of cubosomes
- 5.4 Methods of preparation
- 5.5 Significance and limitations
- 5.6 Therapeutic applications of cubosomes
- 5.7 Conclusion
- References
- Chapter 6. Luminescent nanoclusters for applications in biomedical field
- Abstract
- 6.1 Introduction
- 6.2 Synthesis and characterization of gold nanoclusters
- 6.3 Structure–optical properties relationship
- 6.4 Functionalization for bioapplications
- 6.5 Biosensing strategies
- 6.6 Nanoclusters for multimodal imaging
- 6.7 Nanoclusters as nonlinear optical contrast agents for biological aging
- 6.8 Nanoclusters as nonlinear optical contrast agents for cancer therapy
- 6.9 Conclusion and outlooks
- References
- Chapter 7. Multifunctional magnetic nanoparticles for biomedical applications
- Abstract
- 7.1 Introduction
- 7.2 Methods of synthesizing magnetic nanoparticles
- 7.3 Techniques for magnetic nanoparticle functionalization
- 7.4 Magnetic nanoparticle application in biomedicine
- 7.5 Concluding remarks
- References
- Chapter 8. Self-assembled smart nanostructures for drug delivery applications
- Abstract
- 8.1 Introduction
- 8.2 Self-assembly
- 8.3 Classification of self-assembly
- 8.4 Colloid and surface chemistry of self-assembly
- 8.5 Methods for preparation of assembled nanostructure systems: layer-by-layer method
- 8.6 Types of interactions or forces in self-assembly
- 8.7 Plan of action for drug delivery by nanostructures
- 8.8 Fabrication of self-assembled aggregates
- 8.9 Nanocarriers for drug delivery
- 8.10 Criteria for the fabrication of delivery carriers
- 8.11 Types of nanostructures for drug delivery
- 8.12 Applications of self-assembled nanocarriers in drug delivery
- 8.13 Conclusion and future perspectives
- References
- Chapter 9. Recent advances in cancer nanotheranostics
- Abstract
- 9.1 Introduction
- 9.2 Composition of nanotheranostics
- 9.3 Biological barriers for cancer nanotheranostics
- 9.4 Therapeutic modalities of nanotheranostics
- 9.5 Diagnostic modalities of nanotheranostics
- 9.6 Classification of nanotheranostic agents
- 9.7 Conclusion
- Acknowledgment
- References
- Chapter 10. Application of nanocomposites in dentistry
- Abstract
- 10.1 Introduction
- 10.2 Role of nanocomposites in regeneration of alveolar bone
- 10.3 Nanocomposite materials for functionalization of dental implants
- 10.4 Carbon nanomaterials for implant surface coating
- 10.5 Application of nanocomposites in denture base materials
- 10.6 Orthodontic applications of nanocomposite
- 10.7 Conclusion
- References
- Chapter 11. Protein and peptide nanoparticles for drug delivery applications
- Abstract
- Graphical abstract
- 11.1 Introduction
- 11.2 Protein and peptide nanoparticles
- 11.3 Advantages of PNP in nanomedicine
- 11.4 Enhanced circulation time and stability
- 11.5 Better biocompatibility and biodegradability
- 11.6 Enhanced cellular uptake of NP
- 11.7 Peptides as targeting molecules
- 11.8 Different types of protein and peptide-conjugated nanoparticle
- 11.9 Preparation of protein-based nanoparticles
- 11.10 Application of PNP
- 11.11 PNP and cancer therapy
- 11.12 PNP and cardiovascular diseases
- 11.13 PNP for diabetes
- 11.14 PNP for obesity
- 11.15 PNP for wound healing
- 11.16 Current clinical status of PNP
- 11.17 PNP-drugs approved for clinical use
- 11.18 Conclusions/future direction
- References
- Chapter 12. Ferritin nanocages for targeted drug delivery applications
- Abstract
- 12.1 Introduction
- 12.2 Iron metabolism in mammals
- 12.3 Ferritin versus apoferritin
- 12.4 Ferritin from living sources
- 12.5 Cargo loading into ferritin
- 12.6 Applications of ferritin nanocages
- References
- Chapter 13. Health, safety, and risk assessments of nanomaterials in biomedical field
- Abstract
- 13.1 Introduction
- 13.2 Nanoparticles
- 13.3 Nanostructured material uptake by the human body
- 13.4 Nanotoxicity
- 13.5 Testing of nanomaterials
- 13.6 Approaches for increasing biocompatibility and reducing nanotoxicity of nanostructured materials
- 13.7 Capping of nanoparticles to reduce toxicity in plants
- 13.8 Conclusion
- References
- Index
- Edition: 1
- Published: June 18, 2024
- Imprint: Elsevier
- No. of pages: 486
- Language: English
- Paperback ISBN: 9780323908382
- eBook ISBN: 9780323908399
RV
Raji Vijayamma
Dr Raji Vijayamma is a postdoctoral researcher in Professor Sabu Thomas’ lab at International and Inter University Centre for Nanoscience and Nanotechnology, Mahatma Gandi University,, Kerala, India.
Affiliations and expertise
postdoctoral researcher in Professor Sabu Thomas’ lab at International and Inter University Centre for Nanoscience and Nanotechnology, Mahatma Gandi University, Kerala, India.NK
Nandakumar Kalarikkal
Dr. Nandakumar Kalarikkal is an Associate Professor at the School of Pure and Applied Physics and Joint Director
of the International and Inter University Centre for Nanoscience and Nanotechnology of Mahatma Gandhi University, Kottayam, Kerala, India. His research activities
involve applications of nanostructured materials, laser plasma, and phase transitions. He is the recipient of research fellowships and associateships from prestigious government organizations such as the Department of Science and Technology and Council of Scientific and Industrial Research of the Government of India. He has active collaborations with national and international scientific institutions in India, South Africa, Slovenia, Canada, France, Germany, Malaysia, Australia, and the United States. He has more than 130 publications in peer-reviewed journals. He also co-edited nine books of scientific interest and co-authored many book chapters.
Affiliations and expertise
Director, International and Inter University Centre for Nanoscience and Nanotechnology, and Director and Chair, School of Pure and Applied Physics, Mahatma Gandhi University, Kottayam, Kerala, IndiaST
Sabu Thomas
Prof. Sabu Thomas is a Professor of Polymer Science and Engineering and the Director of the School of Energy Materials at Mahatma Gandhi University, India. Additionally, he is the Chairman of the Trivandrum Engineering Science & Technology Research Park (TrEST Research Park) in Thiruvananthapuram, India. He is the founder director of the International and Inter-university Centre for Nanoscience and Nanotechnology at Mahatma Gandhi University and the former Vice-Chancellor of the same institution.
Prof. Thomas is internationally recognized for his contributions to polymer science and engineering, with his research interests encompassing polymer nanocomposites, elastomers, polymer blends, interpenetrating polymer networks, polymer membranes, green composites, nanocomposites, nanomedicine, and green nanotechnology. His groundbreaking inventions in polymer nanocomposites, polymer blends, green bionanotechnology, and nano-biomedical sciences have significantly advanced the development of new materials for the automotive, space, housing, and biomedical fields. Dr. Thomas has been conferred with Honoris Causa (DSc) by the University of South Brittany, France.
Affiliations and expertise
Professor and Director, International and Interuniversity Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, IndiaRead Nanostructured Materials for Biomedical Applications on ScienceDirect