
Nanomaterials for Photodynamic Therapy
- 1st Edition - January 14, 2023
- Imprint: Woodhead Publishing
- Editor: Prashant Kesharwani
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 8 5 5 9 5 - 2
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 0 3 5 4 - 7
Nanomaterials for Photodynamic Therapy takes a unique approach to this area, with a key focus on the use of nanomaterials and nanocarriers for photodynamic therapy (PDT). The bo… Read more

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Request a sales quoteThe book bridges the gap between the physics and clinical aspects of PDT, offering a unique nanomaterials-focused perspective. This book will prove useful for materials scientists, biomedical engineers, electrical and optical engineers, and pharmaceutical scientists interested in cancer treatment.
- Reviews a broad range of nanomaterials for PDT, such as graphene oxide, dendrimers, solid lipid nanoparticles, and more
- Provides a helpful introduction to the history and mechanism of action behind PDT
- Discusses challenges in clinical translational, particularly in drug-resistant cancers
- Cover image
- Title page
- Table of Contents
- Copyright
- Dedication
- List of contributors
- About the editor
- Preface
- Acknowledgments
- 1. A narrative history of photodynamic therapy
- Abstract
- 1.1 Light
- 1.2 On history
- 1.3 Definition of light treatment
- 1.4 Phototherapy
- 1.5 Photochemotherapy
- 1.6 Photodynamic therapy: basic concepts of discovery
- 1.7 Photodynamic reaction: scientific history of photodynamic therapy
- 1.8 Photosensitizers
- 1.9 Illumination and delivery of light
- 1.10 Dosimetry
- 1.11 Clinical history of modern photodynamic therapy
- 1.12 Photodynamic therapy in Great Britain
- 1.13 Skin
- 1.14 GENITO-URINARY
- 1.15 Esophageal
- 1.16 Lung
- 1.17 Ear, Nose, and Throat/CENTRAL NERVOUS SYSTEM
- 1.18 Ophthalmology
- 1.19 Antimicrobial
- 1.20 Nanotechnology and Photodynamic Therapy
- References
- 2. Mechanisms of photodynamic therapy
- Abstract
- 2.1 Introduction
- 2.2 Mechanisms of photodynamic therapy
- 2.3 Applications of photodynamic therapies in different diseases
- 2.4 Conclusion
- References
- 3. Mechanisms of photodynamic therapy for cancer treatment
- Abstract
- 3.1 Introduction
- 3.2 Advantages and limitations of photodynamic therapy in cancer treatment
- 3.3 Photodynamic therapy components
- 3.4 Mechanism of reactive oxygen species generation by photodynamic action
- 3.5 Molecular damage induced by photodynamic therapy-derived reactive oxygen species
- 3.6 Cancer cell death induced by photodynamic therapy
- 3.7 Indirect effects of photodynamic therapy for tumor eradication
- 3.8 Use of photodynamic therapy for overcoming drug resistance in cancer
- 3.9 Summary points
- Acknowledgments
- References
- 4. Sensitizers in photodynamic therapy
- Abstract
- 4.1 Introduction
- 4.2 Classifications of photosensitizers
- 4.3 Targeted photosensitizers for effective photodynamic therapy
- 4.4 Concluding remarks and future perspectives
- Disclosures
- References
- 5. Polymeric micelles–mediated photodynamic therapy
- Abstract
- Abbreviation and acronym
- 5.1 Introduction
- 5.2 Nanoparticles in photodynamic therapy
- 5.3 Polymeric micelles
- 5.4 Polymeric micelles in anticancer photodynamic therapy
- 5.5 Conclusive summary
- References
- 6. Liposomes in photodynamic therapy
- Abstract
- 6.1 Photodynamic therapy
- 6.2 Liposomes
- 6.3 Liposomes in photodynamic therapy approach
- 6.4 Future perspectives of photodynamic therapy
- References
- 7. Organic nanoparticles in photodynamic therapy
- Abstract
- 7.1 Antimicrobial photodynamic therapy—a brief introduction
- 7.2 Nanoparticle–microbe interaction: mechanisms of action
- 7.3 Antimicrobial photodynamic therapy using organic nanoparticles
- 7.4 Nanoparticles as drug carriers in antimicrobial photodynamic therapy
- 7.5 Biosafety and toxicity considerations of nanoparticles-based antimicrobial photodynamic therapy
- 7.6 Conclusion
- Acknowledgments
- References
- 8. Lipid-based nanoparticles in photodynamic therapy
- Abstract
- List of abbreviations
- 8.1 Introduction
- 8.2 Lipid-based nanoparticles as drug delivery systems
- 8.3 Lipid nanoparticles for photodynamic therapy
- 8.4 Visudyne (Verteporfin for injection): a case of success
- 8.5 Functionalized liposomes as a smart strategy for third generation photodynamic therapy development
- 8.6 Conclusions and remarks for future perspectives
- Dedication
- References
- 9. Solid lipid nanoparticles in photodynamic therapy
- Abstract
- 9.1 History and advances of photodynamic therapy
- 9.2 Advances in the development of nanoparticles as therapeutic agents for anticancer drug delivery
- 9.3 Solid lipid nanoparticles for drug delivery systems
- 9.4 Designing solid lipid nanoparticles: current status and future perspectives
- 9.5 Solid lipid nanoparticles applications and future perspectives
- 9.6 Conclusion
- References
- 10. Actively targeted nanoparticles in photodynamic therapy
- Abstract
- 10.1 Introduction
- 10.2 Utility of nanomaterials in photodynamic therapy
- 10.3 Targeting mechanism involved in photodynamic therapy
- 10.4 Conclusion
- References
- 11. Dendrimers in photodynamic therapy
- Abstract
- 11.1 Introduction
- 11.2 Application of dendrimers in drug delivery and targeting
- 11.3 Approaches of dendrimers for photodynamic therapy
- 11.4 Different dendrimers involved in photodynamic therapy
- 11.5 Design and development of dendrimers for photodynamic therapy
- 11.6 Dendrimer strategies for cancer and other diseases
- 11.7 Conclusion and future perspective
- Acknowledgments
- References
- 12. Carbon nanomaterials for photothermal therapy
- Abstract
- 12.1 Introduction
- 12.2 Carbon dots
- 12.3 Carbon nanoparticles
- 12.4 Carbon nanotubes
- 12.5 Graphene
- 12.6 Other carbonaceous nanomaterials used for photothermal therapy
- 12.7 Challenges
- 12.8 Conclusion
- References
- 13. Fullerenes and fullerene–dye structures in photodynamic therapy
- Abstract
- 13.1 Introduction
- 13.2 Structure, physical, and chemical properties of fullerenes
- 13.3 Fullerene–dye structures—the theoretical background
- 13.4 Fullerene–dye—types of chemical structures
- 13.5 Summary: key points for the design of fullerene-based photosensitizers for PDT
- 13.6 Conclusion
- Acknowledgments
- References
- 14. Quantum dots in photodynamic therapy
- Abstract
- Abbreviations
- 14.1 Introduction
- 14.2 Synthesis of quantum dots
- 14.3 Photophysical and photochemical properties of quantum dots
- 14.4 Biological applications
- 14.5 Conclusion
- References
- 15. Photodynamic therapy in cosmetics
- Abstract
- 15.1 Introduction
- 15.2 Cosmetic applicability of photodynamic therapy
- 15.3 Conclusion
- References
- 16. Translational aspects of photodynamic therapy in drug-resistant cancer
- Abstract
- 16.1 Introduction
- 16.2 Basic concepts and elements of photodynamic therapy
- 16.3 Drug resistance in cancer
- 16.4 Preclinical assessment of photodynamic therapy and evaluation in drug-resistant cancer models
- 16.5 Clinical use of photodynamic therapy
- 16.6 Innovative and combinatorial approaches in photodynamic therapy
- References
- 17. Toward photodynamic cancer chemotherapy with C60-Doxorubicin nanocomplexes
- Abstract
- 17.1 Introduction
- 17.2 Photodynamic therapy with C60
- 17.3 Drug delivery with C60
- 17.4 Photodynamic chemotherapy with C60
- 17.5 Outlook
- References
- 18. Challenges, conclusions, and future aspects of photodynamic therapy
- Abstract
- 18.1 Introduction
- 18.2 Challenges, conclusions, and future perspectives of photodynamic therapy
- References
- Index
- Edition: 1
- Published: January 14, 2023
- Imprint: Woodhead Publishing
- No. of pages: 568
- Language: English
- Paperback ISBN: 9780323855952
- eBook ISBN: 9780323903547
PK
Prashant Kesharwani
Dr. Prashant Kesharwani is assistant professor of Pharmaceutics at Department of Pharmaceutical Sciences, Dr. Harisingh Gour Vishwavidyalaya, Sagar, Madhya Pradesh, India. He has more than 12 years of teaching, research, and industrial experience at international levels from various countries, including the United States, Malaysia, and India. An overarching goal of his current research is the development of nanoengineered drug delivery systems for various diseases. He has more than 350 international publications in well-reputed journals and more than 25 international books (Elsevier). He is a recipient of many research grants from various funding bodies. He is also the recipient of several internationally acclaimed awards, such as “USERN Laureate award”, most prestigious “SERB-Ramanujan Fellowship Award”. He actively participates in outreach and scientific dissemination for the service of the wider community. His Number of citations is = 26779; h-index = 85; i-10 index = 370 (According to google scholar on March 2025). He has more than 30 international publications published in very high impact factor journals (Progress in Polymer Sciences IF 32.063, Molecular Sciences IF 41.444, Progress in Material Sciences IF 48.580, Advanced Materials IF 29.4, Drug Resistance Update IF 22.841 and Material Todays IF 32.072). He has presented many invited talks and oral presentations at prestigious scientific peer-conferences, received international acclaims and awards for research contribution, supervised students/junior researchers and actively participated in outreach and scientific dissemination for the service of the wider community.