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Monoclonal Antibodies against Bacteria
1st Edition - August 22, 1985
Editor: Alberto Macario
eBook ISBN:9780323154420
9 7 8 - 0 - 3 2 3 - 1 5 4 4 2 - 0
Monoclonal Antibodies against Bacteria, Volume I explores the generation, characterization, and utilization of monoclonal antibodies against bacteria and on other monoclonal… Read more
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Monoclonal Antibodies against Bacteria, Volume I explores the generation, characterization, and utilization of monoclonal antibodies against bacteria and on other monoclonal products relevant to antibacterial immune responses. Organized into 12 chapters, this book begins with a discussion on monoclonal antibodies against bacteria, encompassing its scope, research, and directions. It shows that the coordinated use of antisera and panels of monoclonal antibodies is proving useful for classification as a diagnostic tool with prognostic implications in the case of pathogens, or as a preliminary step in taxonomy. Also, monoclonal antibodies hold great potential as instruments in working with bacteria for industrial or biotechnological purposes, including genetic engineering. This book also elucidates the use of monoclonal antibodies of predefined molecular specificity for tracing molecular ""signatures"" left by a given strain in other microorganisms, subcellular structures, and materials from ecologic niches. The possibility of antibacterial and antitoxin therapies with monoclonal antibodies is also addressed. This treatise will be a valuable reference work to anyone working with monoclonal antibodies or getting ready to prepare them against the strain(s) (or bacterial structures) of his/her interest.
Contributors
Preface
Introduction: Monoclonal Antibodies against Bacteria for Medicine, Dentistry, Veterinary Sciences, Biotechnology, and Industry—An Overview
Contents of Volume II
1 Monoclonal Antibodies against Gonococcal Pili: Uses in the Analysis of Gonococcal Immunochemistry and Virulence
I. Introduction
II. Background
III. Results and Discussion
IV. Conclusions
V. Prospects for the Future
VI. Summary
References
2 Monoclonal Antibodies against Group B Streptococcus
I. Introduction
II. Background
III. Methods and Results
IV. Conclusions
V. Summary
References
3 Studies with Monoclonal Antibodies to Mycobacteria
I. Introduction
II. Results and Discussion
III. Conclusions and Prospects for the Future
IV. Summary
References
4 Monoclonal Antibodies to Characterize the Antigenic Heterogeneity of Bacteroides intermedius
I. Introduction
II. Background
III. Results and Discussion
IV. Conclusions
V. Prospects for the Future
VI. Summary
References
5 Monoclonal Antibodies against Legionella pneumophila Serogroup 1 Antigens: Characterization and Their Potential Applications
I. Introduction
II. Background
III. Results and Discussion
IV. Conclusions
V. Prospects for the Future
VI. Summary
References
6 Monoclonal Antibodies Specific for the O-Antigen of Shigella flexneri and Shigella sonnei: Immunochemical Characterization and Clinical Usefulness
I. Introduction
II. Background
III. Results and Discussion
IV. Conclusions and Prospects for the Future
V. Summary
References
7 Monoclonal Antibodies against Group- and Type-Specific Antigens of Vibrio cholerae O:1
I. Introduction
II. Background
III. Results and Discussion
IV. Conclusions
V. Prospects for the Future
VI. Summary
References
8 Monoclonal Antibodies against Tetanus Toxin and Tetanus Toxoid
I. Introduction
II. Background
III. Methods for Generation of Monoclonal Antibodies
IV. Results and Discussion
V. Prospects for the Future
VI. Summary
References
9 Human Monoclonal Antibodies for Prophylaxis and Therapy of Bacterial Infections
I. Introduction
II. Background
III. Results and Discussion
IV. Conclusions and Future Prospects
V. Summary
References
10 Monoclonal T Cells and T-Cell Hybridomas with Antibacterial Activity
I. Introduction
II. Background
III. Results and Discussion
IV. Conclusions and Prospects for the Future
V. Summary
References
11 A Preview of the Uses of Monoclonal Antibodies against Methanogens in Fermentation Biotechnology: Significance for Public Health
I. Introduction
II. Background
III. Results and Discussion
IV. Conclusions
V. Prospects for the Future
VI. Summary
References
12 An International Hybridoma Data Bank: Aims, Structure, Function