Molecular Biology
- 4th Edition - April 1, 2027
- Latest edition
- Authors: David P. Clark, Nanette J. Pazdernik, Michelle R. McGehee, Kelly S Bender
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 4 5 3 6 0 - 1
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 4 5 3 6 1 - 8
Molecular Biology 4th edition provides a thoroughly revised, invaluable resource for college and university students in the life sciences, medicine and related fields. This… Read more
Purchase options
Molecular Biology 4th edition provides a thoroughly revised, invaluable resource for college and university students in the life sciences, medicine and related fields. This esteemed text continues to meet the needs of students and professors by including chapters on RNA, genome editing systems such as CRISPR/Cas9, and epigenetics, emphasizing the latest advances in each of these rapidly expanding areas of research. The book includes a new unit focused on -omics, taking the student through an understanding of the different types of information garnered from these comprehensive, high-throughput research studies. This volume effectively introduces basic concepts that are followed by more specific applications as the text evolves, with the goal of providing a strong foundation of knowledge that is essential for subsequent courses in biotechnology, advanced gene regulation, cell metabolism, and cancer biology.
• Winner of a 2020 Textbook Excellence Award (College) (Texty) from the Textbook and Academic Authors Association
• Features an entire unit dedicated to -omics research, including chapters on genomics/epigenomics, transcriptomics, and proteomics/metabolomics
• Includes expanded coverage about the function of RNA, genome editing systems such as CRISPR/Cas9, and epigenetic effects on cellular function
• Provides an ancillary package with updated PowerPoint slide images, clicker questions, and a test bank to reduce the workload for the instructor
• Features an entire unit dedicated to -omics research, including chapters on genomics/epigenomics, transcriptomics, and proteomics/metabolomics
• Includes expanded coverage about the function of RNA, genome editing systems such as CRISPR/Cas9, and epigenetic effects on cellular function
• Provides an ancillary package with updated PowerPoint slide images, clicker questions, and a test bank to reduce the workload for the instructor
Biology students who have completed an introductory biology, chemistry, and genetics course.
Unit 1: Basic Technical and Biological Principles
1. From Molecules to Organisms
2. Genes, Genomes, and DNA
3. Working with Nucleic Acids
4. Polymerase Chain Reaction
5. Cloning Genes
6. DNA Sequencing
Unit 2: The Central Dogma of Molecular Biology
7. Cell Division and DNA Replication
8. Transcription of Genes
9. Processing of RNA 10. Protein Synthesis
11. Protein Structure and Function
Unit 3: Regulating Gene Expression
12. Regulation of Transcription in Prokaryotes
13. Regulation of Transcription in Eukaryotes
14. Regulation of Protein Synthesis
15. Noncoding RNA
16. CRISPR-Cas Systems
17. Analysis of Gene Expression
Unit 4: Omics Research—NEW
Unit 12. Genomics and Systems Biology (Previously Ch. 9)
13. Epigenetics and Epigenomics (Prev Ch. 22)
14. Microbiomics and Metagenomics (NEW)
15. Transcriptomics (NEW)
16. Proteomics: Global Analysis of Proteins (Prev Ch. 15)
17. Metabolomics (including Lipidomics) (NEW)
Unit 5: Subcellular Genetic Elements
18. Plasmids
19. Viruses, Viroids, and Prions
20. Mobile DNA
Unit 6: Changing the DNA Blueprint
21. DNA Damage and Repair
22. Recombination
23. Bacterial Genetics
24. Molecular Evolution
1. From Molecules to Organisms
2. Genes, Genomes, and DNA
3. Working with Nucleic Acids
4. Polymerase Chain Reaction
5. Cloning Genes
6. DNA Sequencing
Unit 2: The Central Dogma of Molecular Biology
7. Cell Division and DNA Replication
8. Transcription of Genes
9. Processing of RNA 10. Protein Synthesis
11. Protein Structure and Function
Unit 3: Regulating Gene Expression
12. Regulation of Transcription in Prokaryotes
13. Regulation of Transcription in Eukaryotes
14. Regulation of Protein Synthesis
15. Noncoding RNA
16. CRISPR-Cas Systems
17. Analysis of Gene Expression
Unit 4: Omics Research—NEW
Unit 12. Genomics and Systems Biology (Previously Ch. 9)
13. Epigenetics and Epigenomics (Prev Ch. 22)
14. Microbiomics and Metagenomics (NEW)
15. Transcriptomics (NEW)
16. Proteomics: Global Analysis of Proteins (Prev Ch. 15)
17. Metabolomics (including Lipidomics) (NEW)
Unit 5: Subcellular Genetic Elements
18. Plasmids
19. Viruses, Viroids, and Prions
20. Mobile DNA
Unit 6: Changing the DNA Blueprint
21. DNA Damage and Repair
22. Recombination
23. Bacterial Genetics
24. Molecular Evolution
- Edition: 4
- Latest edition
- Published: April 1, 2027
- Language: English
DC
David P. Clark
David P. Clark did his graduate work on bacterial antibiotic resistance to earn his Ph.D. from Bristol University, England. He later crossed the Atlantic to work as a postdoctoral researcher at Yale University and then the University of Illinois. Dr Clark recently retired from teaching Molecular Biology and Bacterial Physiology at Southern Illinois University which he joined in 1981. His research into the Regulation of Alcohol Fermentation in E. coli was funded by the U.S. Department of Energy, from 1982 till 2007. In 1991 he received a Royal Society Guest Research Fellowship to work at Sheffield University, England while on sabbatical leave.
Affiliations and expertise
Southern Illinois UniversityNP
Nanette J. Pazdernik
Nanette J. Pazdernik has devoted her career to the understanding of molecular biology and biotechnology, and then disseminating that knowledge by writing and teaching. She is a co-author of Biotechnology, 2nd edition and Molecular Biology, 3rd edition, with Dr. David P. Clark and Dr. Michelle McGehee. Both the second and third edition of Molecular Biology won a Texty award from the Textbook and Academic Authors Association. She has taught courses in General Biology, Genetics, as well as Anatomy and Physiology at Southwestern Illinois College, McKendree University, and Harris-Stowe University. She received her BA in Biology from Lawrence University in Appleton, Wisconsin, and her PhD in Molecular, Cellular, Developmental Biology and Genetics from the University of Minnesota. Her doctoral thesis studied protein structure-function relationships. Following her degrees, she investigated the signal transduction pathways that control apoptosis and immunity at Indiana University School of Medicine. In a second post-doctoral position, she studied the various molecules that maintain the stem cell niche in the Department of Genetics at Washington University School of Medicine in St. Louis, MO. Currently, Dr. Pazdernik works in the biotech industry as a scientific writer.
Affiliations and expertise
Integrated DNA TechnologiesMM
Michelle R. McGehee
Michelle R. McGehee earned a BA in Microbiology in 2000 and a PhD in Molecular Biology, Microbiology, and Biochemistry in 2005, both from Southern Illinois University in Carbondale, USA. Her graduate research focused on the genetic and biochemical regulation of lactate fermentation in Escherichia coli. Michelle is currently an assistant academic dean and biology professor at a college in Texas, where she teaches courses in both microbiology and genetics.
Affiliations and expertise
Blinn College