Molecular Biology of Neurodegenerative Diseases: Visions for the Future - Part B
- 1st Edition, Volume 177 - January 16, 2021
- Editor: David B. Teplow
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 2 4 1 4 3 - 1
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 2 4 1 4 4 - 8
Molecular Biology of Neurodegenerative Diseases: Visions for the Future, Part B, Volume 177 in the Progress in Molecular Biology and Translational Science series, provides the… Read more
Molecular Biology of Neurodegenerative Diseases: Visions for the Future, Part B, Volume 177 in the Progress in Molecular Biology and Translational Science series, provides the most topical, informative and exciting monographs available on a wide variety of research topics. The series includes in-depth knowledge on the molecular biological aspects of organismal physiology, with this release including chapters on Alzheimer's disease, Prion-like propagation of alpha-synuclein, What - if anything - can we learn about neurodegenerative diseases from yeast?, Mitochondrial rejuvenation and replacement as a novel strategy for treatment of age-related neurodegenerative diseases, and more.
- Includes comprehensive coverage of molecular biology
- Presents ample use of tables, diagrams, schemata and color figures to enhance the reader's ability to rapidly grasp the information provided
- Contains contributions from renowned experts in the field
Scientists working actively in a field, including those at levels ranging from graduate student to senior investigator. New investigators to a field who wish to familiarize themselves with the latest work
Preface
David Teplow
1. Relevance of transgenic mouse models for Alzheimer's disease
Leon Tai, Juan Maldonado Weng, Mary Jo LaDu and Scott Brady
2. Mitochondrial transplant to replenish damaged mitochondria: A novel therapeutic strategy for neurodegenerative diseases?
Abhisek Mukherjee, Andrea D Becerra Calixto, Melissa Chavez, Jean Paul Delgado Charris and Claudio Soto
3. Activity-dependent neuroprotective protein (ADNP)-end-binding protein (EB) interactions regulate microtubule dynamics toward protection against tauopathy
Yanina Ivashko-Pachima and Illana Gozes
4. Applying available knowledge and resources to alleviate familial and sporadic neurodegenerative disorders
Mark P. Mattson
5. The cellular machinery of post-endocytic APP trafficking in Alzheimer's disease: A future target for therapeutic intervention?
Lawrence S.B. Goldstein and Utpal Das
6. The search for novel targets in Alzheimer's disease—The 90s redux
Christian Behl
7. Adult hippocampal neurogenesis in Alzheimer's disease
Ahmed Disouky and Orly Lazarov
8. Early detection and personalized medicine: Future strategies against Alzheimer's disease
Antonio Di Meco and Robert Vassar
9. Inflammation and Parkinson’s disease pathogenesis: Mechanisms and therapeutic insight
Gianluigi Forloni, Pietro la Vitola, Milica Cerovic and Claudia Balducci
- Edition: 1
- Volume: 177
- Published: January 16, 2021
- Language: English
DT
David B. Teplow
David B. Teplow, Ph.D., is a Professor of Neurology, Emeritus, at UCLA and an internationally recognized leader in efforts to understand and treat Alzheimer's disease. Dr. Teplow's group has used a multi-disciplinary approach to determine how neurotoxic peptides, such as the amyloid β-protein (Alzheimer's disease) and α-synuclein (Parkinson’s disease), form neurotoxic structures that kill neurons and to develop the means to block these processes. Dr. Teplow received undergraduate training at UC Berkeley; a Ph.D. from the University of Washington; and was a postdoctoral scholar at Caltech. Before coming to UCLA, Dr. Teplow was a faculty member in the Department of Neurology, Harvard Medical School. Dr. Teplow has published >250 peer-reviewed articles, books and book chapters, and commentaries, in addition to serving on numerous national and international scientific advisory boards. Dr. Teplow was a founding editor of the Journal of Molecular Neuroscience and Current Chemical Biology, He is Co-Editor-in-Chief of the Elsevier serial Progress in Molecular Biology and Translational Science and is Associate Editor-in-Chief of the American Journal of Neurodegenerative Disease.
Affiliations and expertise
Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA, USARead Molecular Biology of Neurodegenerative Diseases: Visions for the Future - Part B on ScienceDirect