Modern Sample Preparation for Chromatography
- 2nd Edition - February 24, 2021
- Imprint: Elsevier
- Authors: Serban C. Moldoveanu, Victor David
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 2 1 4 0 5 - 3
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 8 9 8 2 0 - 1
Modern Sample Preparation for Chromatography, Second Edition explains the principles of sample preparation for chromatographic analysis. A variety of procedures are applied to mak… Read more
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Request a sales quoteModern Sample Preparation for Chromatography, Second Edition explains the principles of sample preparation for chromatographic analysis. A variety of procedures are applied to make real-world samples amenable for chromatographic analysis and to improve results. This book's authors discuss each procedure’s advantages, disadvantages and their applicability to different types of samples, along with their fit for different types of chromatographic analysis. The book contains numerous literature references and examples of sample preparation for different matrices and new sections on green approaches in sample preparation, progress in automation of sample preparation, non-conventional solvents for LLE (ionic liquids, deep eutectic mixtures, and others), and more.
- Presents numerous techniques applied for sample preparation for chromatographic analysis
- Provides an up-to-date source of information regarding the progress made in sample preparation for chromatography
- Describes examples for specific types of matrices, providing a guide for choosing the appropriate sample preparation method for a given analysis
Analytical chemists involved in separation science; chemists of a wide range of levels from industry, research and academic sectorsPost graduate and upper undergraduate students in analytical chemistry
- Cover image
- Title page
- Table of Contents
- Copyright
- Preface
- I. General concepts in sample preparation
- Chapter 1. Preliminaries to sample preparation
- 1.1. Collection of information and planning for a chromatographic analysis
- 1.2. Statistical evaluation of quantitative data
- 1.3. Validation of an analytical method
- 1.4. Sampling
- Chapter 2. The role of sample preparation
- 2.1. Preliminary processing of the sample
- 2.2. Routine manipulations of the sample
- 2.3. Sample cleanup and fractionation
- 2.4. Concentration of the sample
- 2.5. Chemical modifications of the sample
- 2.6. Selection of a sample preparation procedure
- 2.7. Automation and high throughput in sample preparation
- Chapter 3. Chromatography as a core step for an analytical procedure
- 3.1. Basic concepts in chromatography
- 3.2. Overview of gas chromatography
- 3.3. Overview of high-performance liquid chromatography
- 3.4. Other chromatography types used as core analytical method
- II. Main sample preparation techniques
- Chapter 4. Mechanical processing in sample preparation
- 4.1. Grinding and sieving
- 4.2. Filtration, microfiltration, and ultrafiltration
- 4.3. Centrifugation
- Chapter 5. Phase transfer in sample preparation
- 5.1. Distillation, vaporization, and drying
- 5.2. Physical dissolution, crystallization, and precipitation
- Chapter 6. Solvent extraction
- 6.1. Properties of solvents relevant in the extraction process
- 6.2. Conventional liquid–liquid extraction
- 6.3. Special liquid–liquid extraction procedures
- 6.4. Conventional liquid–solid extraction
- 6.5. Accelerated solvent extraction
- 6.6. Microwave-assisted solvent extraction and ultrasound-assisted extraction
- 6.7. Supercritical solvent extraction
- 6.8. Solvent-gas extraction
- Chapter 7. Solid-phase extraction
- 7.1. Conventional solid-phase extraction
- 7.2. Chemical nature of materials used as SPE sorbent and their characterization
- 7.3. Types of SPE sorbents according to their functionalities or function
- 7.4. Formats used in SPE
- 7.5. Retention and elution mechanisms in SPE
- 7.6. Solvents used in solid-phase extraction
- 7.7. Selection and optimization of solid-phase extraction
- 7.8. Solid-phase extraction from headspace
- 7.9. Solid-phase microextraction
- 7.10. Stir-bar sorptive extraction
- 7.11. Matrix solid-phase dispersion
- 7.12. QuEChERS technique
- Chapter 8. Chromatographic procedures as preliminary separations
- 8.1. Thin-layer and open column liquid chromatography as sample preparation
- 8.2. Size-exclusion chromatography used in sample preparation
- 8.3. Other chromatographic techniques used for sample preparation
- Chapter 9. Membrane separations as sample preparation techniques
- 9.1. Gas diffusion through membranes
- 9.2. Membranes used in special liquid–liquid extraction
- 9.3. Reversed osmosis and dialysis
- Chapter 10. Electroseparations in sample preparation
- 10.1. Electrophoretic techniques
- 10.2. Other electroseparation techniques
- Chapter 11. Other separation techniques in sample preparation
- 11.1. Overview of ion exchange use in sample preparation
- 11.2. Other techniques in sample preparation
- Chapter 12. The role of derivatization in chromatography
- 12.1. Derivatization for sample dissolution
- 12.2. Improvement of gas chromatographic analysis by derivatization
- 12.3. Improvement of liquid chromatographic analysis by derivatization
- 12.4. Derivatization for chiral separations
- Chapter 13. Chemical reactions used in analytical derivatizations
- 13.1. Reactions with formation of alkyl or aryl derivatives
- 13.2. Reactions with formation of silyl derivatives
- 13.3. Derivatives formation through acylation reactions
- 13.4. Reactions of addition to carbon–heteroatom multiple bonds involved in derivatization
- 13.5. Derivatization reactions with formation of cyclic compounds
- 13.6. Other derivatization reactions
- 13.7. Derivatization reactions on solid support or involving solid-phase reagents
- Chapter 14. Chemical degradation of polymers for chromatographic analysis
- 14.1. Chemical degradation of polymeric carbohydrates
- 14.2. Chemical degradation of proteins for chromatographic analysis
- 14.3. Chemical degradation of other macromolecular compounds for chromatographic analysis
- Chapter 15. Comments on sample preparation in chromatography for different types of materials
- 15.1. Sample preparation techniques for the environmental analysis (air, water, and soil)
- 15.2. Sample preparation for the analysis of pharmaceuticals
- 15.3. Sample preparation for the analysis of biological samples
- 15.4. Sample preparation for food and agricultural products
- 15.5. Sample preparation related to the analysis of other materials and/or processes
- Index
- Edition: 2
- Published: February 24, 2021
- Imprint: Elsevier
- No. of pages: 696
- Language: English
- Paperback ISBN: 9780128214053
- eBook ISBN: 9780323898201
SM
Serban C. Moldoveanu
Serban C. Moldoveanu was Senior Principal Scientist at R. J. Reynolds Tobacco Company, USA, and retired at the end of 2023. His research activity was focused on various aspects of chromatography including method development for the analysis by GC/MS, HPLC, and LC/MS/MS of natural products and cigarette smoke. He has also performed research on pyrolysis of a variety of polymers and small molecules. He has written over 150 publications in peer reviewed journals, eleven books, and several chapter contributions. He is a member of the editorial board of the Journal of Analytical Methods in Chemistry and of Frontiers in Chemistry.
Affiliations and expertise
Senior Principal Scientist, RJ Reynolds Tobacco Co., Winston-Salem, NC, USAVD
Victor David
Victor David was a Professor and Head of the Department of Analytical Chemistry, University of Bucharest, Romania. Recently retired, he remains Emeritus Professor at the same Department. His main field of research is separation science (theory and applications in various scientific domains). He is the author of more than 200 publications, including over 150 scientific papers in peer reviewed journals and 25 books and chapters. He is member of editorial board of Biomedical Chromatography, Molecules, Journal of Essential Oil-Bearing Plants and Revue Roumaine de Chimie.
Affiliations and expertise
Professor and Head of the Department of Analytical Chemistry, University of Bucharest, RomaniaRead Modern Sample Preparation for Chromatography on ScienceDirect