
Modern Approaches for Evaluation and Treatment of GI Motility Disorders, An Issue of Gastroenterology Clinics of North America
- 1st Edition, Volume 49-3 - August 5, 2020
- Imprint: Elsevier
- Editor: Henry Parkman
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 7 1 2 9 9 - 6
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 7 1 3 0 0 - 9
Together with Consulting Editor, Dr. Alan Buchman, Dr. Parkman has created as state-of-the-art issue devoted to the modern technology and approaches for evaluation and treatment of… Read more

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Request a sales quoteTogether with Consulting Editor, Dr. Alan Buchman, Dr. Parkman has created as state-of-the-art issue devoted to the modern technology and approaches for evaluation and treatment of GI motility. He has provided coverage for the esophagus, colon, small intestine, and gut. Leaders in the field have contributed the detailed clinical review articles on the following topics: Enhancing High Resolution Esophageal Manometry: Use of Impedance, multiple rapid swallows, Position change, Solid food boluses, and other techniques; EndoFLIP in the esophagus: Assessing sphincter function, wall stiffness, motility to guide treatments; Evaluation and Treatment of patients with persistent reflux symptoms despite PPI treatment; Esophageal Evaluation for Patients undergoing Lung Transplant Evaluation: What should we do for evaluation and management; Tailoring Endoscopic and Surgical Treatments for GERD; Endoscopic and Surgical Treatments for Achalasia: Who to treat and how; Enhancing Scintigraphy for evaluation of gastric, small bowel, colonic motility; Targeting treatment for gastroparesis: Use of clinical tests to guide treatments; Endoscopic and Surgical Treatments for Gastroparesis: What to do and Whom to treat; Gastric Biopsies in Gastroparesis: Insights to Gastric Neuromuscular Disorders to Help with treatment; SIBO: How to diagnose and treat (and then treat again); Assessing anorectal function in constipation and fecal incontinence; Treating chronic abdominal pain in patients with Chronic Recurrent Abdominal Pain and IBS; and Refractory Chronic Constipation: How to evaluate and treat. Gastroenterologists will come away with the technical information they need to improve outcomes in their patients.
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Forthcoming Issues
- Foreword
- Preface
- Esophagus
- Enhancing High-Resolution Esophageal Manometry: Use of Ancillary Techniques and Maneuvers
- Key points
- Introduction
- High-resolution impedance manometry
- Upright swallows during high-resolution manometry and high-resolution impedance manometry
- Bolus volume and consistency
- Physiologic provocative maneuvers
- Pharmacologic provocative maneuvers
- Postprandial monitoring
- Ambulatory manometry
- Future research
- Summary
- EndoFLIP in the Esophagus: Assessing Sphincter Function, Wall Stiffness, and Motility to Guide Treatment
- Key points
- Introduction
- The functional luminal imaging probe catheter, study protocol, and data analysis
- Assessing motility
- Assessing the sphincter function
- Assessing wall stiffness
- Summary
- Evaluation and Treatment of Patients with Persistent Reflux Symptoms Despite Proton Pump Inhibitor Treatment
- Key points
- Varying definitions of proton pump inhibitor–refractory gastroesophageal reflux disease symptoms
- Proton pump inhibitor–refractory heartburn
- Treatments other than proton pump inhibitors
- Management of patients with heartburn refractory to proton pump inhibitor therapy
- Esophageal Evaluation for Patients Undergoing Lung Transplant Evaluation: What Should We Do for Evaluation and Management
- Key points
- Introduction
- Gastroesophageal reflux disease and lung disease
- Esophageal dysmotility and lung disease
- Aspiration and gastroesophageal reflux disease in lung transplant
- Testing in lung transplant evaluation and lung transplant recipients
- Treatment
- Scleroderma and lung transplantation
- Summary
- Tailoring Endoscopic and Surgical Treatments for Gastroesophageal Reflux Disease
- Key points
- Introduction
- Pathophysiology of gastroesophageal reflux disease and esophageal dysmotility
- Effects of surgical fundoplication on esophageal motility and manometry parameters
- Surgical fundoplication in patients with ineffective esophageal motility
- Surgical fundoplication in patients with esophageal aperistalsis
- Endoscopic management of gastroesophageal reflux disease
- Summary
- Endoscopic and Surgical Treatments for Achalasia: Who to Treat and How?
- Key points
- Introduction
- History of surgical therapy for achalasia
- Surgical therapy for achalasia
- Endoscopic therapy for achalasia
- Peroral endoscopic myotomy
- Gastroesophageal reflux after peroral endoscopic myotomy
- Chronic and end-stage achalasia
- Achalasia: a risk factor for carcinoma
- Future direction
- Summary
- Gastric
- Enhancing Scintigraphy for Evaluation of Gastric, Small Bowel, and Colonic Motility
- Key points
- Introduction
- Standardization and alternative meal enhancements
- Combined solid with liquid meal enhancements
- Enhancements in glucose control during gastric emptying studies
- Enhancements in solid meal intragastric meal distribution and fundic accommodation
- Enhanced assessment of dynamic antral and antropyloroduodenal motility
- Enhanced whole-gut transit scintigraphy
- Appropriate use criteria and Current Procedural Terminology coding enhancements for gastrointestinal scintigraphy
- Enhanced semiautomated commercial software for analysis
- Summary
- Targeting Treatment of Gastroparesis: Use of Clinical Tests to Guide Treatments
- Key points
- Introduction
- Treatments of gastroparesis
- Guiding decisions in suspected gastroparesis by emptying rates
- Guiding decisions by other tests in suspected gastroparesis
- Summary
- Endoscopic and Surgical Treatments for Gastroparesis: What to Do and Whom to Treat?
- Key points
- Introduction
- Endoscopic Botox pyloric therapy
- Gastric peroral endoscopic myotomy/peroral pyloromyotomy (GPOEM/POP)
- Surgical pyloromyotomy and pyloroplasty
- Enteral access
- Gastric electrical stimulation
- Combination of gastric electrical stimulation and pyloromyotomy
- Gastrectomy
- Decision-making for surgical treatments
- Gastric Biopsies in Gastroparesis: Insights into Gastric Neuromuscular Disorders to Aid Treatment
- Key points
- Introduction
- Cellular control of normal gastric function
- Cellular abnormalities associated with the pathogenesis of gastroparesis
- Deep molecular profiling in gastroparesis
- Correlation with clinical symptoms and gastric emptying
- Future directions
- Small Intestine
- Small Intestinal Bacterial Overgrowth: How to Diagnose and Treat (and Then Treat Again)
- Key points
- Introduction
- Pathophysiology
- Diagnosis
- Treatment of small intestinal bacterial overgrowth
- Summary
- Colon
- Assessing Anorectal Function in Constipation and Fecal Incontinence
- Key points
- Introduction
- Assessment of symptoms
- Digital rectal examination
- Anorectal manometry
- Rectal sensation testing
- Balloon expulsion testing
- Defecography
- Anal ultrasound
- Endoanal and external phased-array MRI
- Neurophysiology testing
- Electromyography
- Pudendal nerve terminal motor latency
- Translumbosacral anorectal magnetic stimulation test
- Newer techniques
- Summary
- Treating Chronic Abdominal Pain in Patients with Chronic Abdominal Pain and/or Irritable Bowel Syndrome
- Key points
- Introduction
- Clinical approach
- Treatment strategies
- Summary
- Refractory Constipation: How to Evaluate and Treat
- Key points
- Introduction
- Refractory constipation: terminology
- Refractoriness of constipation may result from uncontrolled underlying disease or treatment
- Clinical testing in patients with refractory constipation
- Differentiating subtypes of primary chronic idiopathic constipation
- Common pitfalls in assessment of refractory chronic constipation
- Significant colonic diseases resulting in slow transit constipation
- Choice of therapy for refractory chronic constipation
- The special circumstance of descending perineum syndrome and Ehlers-Danlos syndrome
- Summary
- Edition: 1
- Volume: 49-3
- Published: August 5, 2020
- Imprint: Elsevier
- No. of pages: 240
- Language: English
- Hardback ISBN: 9780323712996
- eBook ISBN: 9780323713009
HP
Henry Parkman
Henry Parkman is the Vice Chair of Research, Department of Medicine Professor and Medicine Director at the GI Motility Laboratory at the Lewis Katz School of Medicine. His main areas of research include the use of multichannel electrogastrography to assess gastric myoelectrical activity to detect gastric motor function in patients with dyspeptic symptoms. He has developed a noninvasive test to measure simultaneously both gastric emptying and gastric volume after ingestion of a solid meal under physiologic conditions which is useful in defining the pathophysiologic factors which cause symptoms in patients with functional dyspepsia and be useful to test the effects of new pharmaceutical agents. He is also investigating gastric motility, breath tests for gastric emptying, electrogastrography (EGG), new pharmaceutical treatments for gastroparesis and functional dyspepsia, small bowel motility recordings, esophageal pH and motility recordings.
Affiliations and expertise
Vice Chair of Research, Department of Medicine Professor, GI Motility Laboratory, Lewis Katz School of Medicine; and Medicine Director, ISA