Modeling and Control of Drug Delivery Systems
- 1st Edition - February 6, 2021
- Imprint: Academic Press
- Editor: Ahmad Taher Azar
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 2 1 1 8 5 - 4
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 2 1 1 9 5 - 3
Modeling and Control of Drug Delivery Systems provides comprehensive coverage of various drug delivery and targeting systems and their state-of-the-art related works, ranging f… Read more
Purchase options
Institutional subscription on ScienceDirect
Request a sales quoteModeling and Control of Drug Delivery Systems provides comprehensive coverage of various drug delivery and targeting systems and their state-of-the-art related works, ranging from theory to real-world deployment and future perspectives. Various drug delivery and targeting systems have been developed to minimize drug degradation and adverse effect and increase drug bioavailability. Site-specific drug delivery may be either an active and/or passive process. Improving delivery techniques that minimize toxicity and increase efficacy offer significant potential benefits to patients and open up new markets for pharmaceutical companies.
This book will attract many researchers working in DDS field as it provides an essential source of information for pharmaceutical scientists and pharmacologists working in academia as well as in the industry. In addition, it has useful information for pharmaceutical physicians and scientists in many disciplines involved in developing DDS, such as chemical engineering, biomedical engineering, protein engineering, gene therapy.
- Presents some of the latest innovations of approaches to DDS from dynamic controlled drug delivery, modeling, system analysis, optimization, control and monitoring
- Provides a unique, recent and comprehensive reference on DDS with the focus on cutting-edge technologies and the latest research trends in the area
- Covers the most recent works, in particular, the challenging areas related to modeling and control techniques applied to DDS
Researchers, graduate students, engineers and practitioners in Biomedical Engineering, Control Engineering, Chemical Engineering, Computer Engineering and Computer Science. Researchers, graduate students, and practitioners in Electrical and Electronics Engineering; Mathematics and Applied Mathematics; Engineering Mathematics; Physics; Computational Physics; and Pharmaceutical Sciences
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Preface
- About the book
- Objectives of the book
- Organization of the book
- Book features
- Audience
- Acknowledgments
- Chapter 1: Hepatitis C Virus Epidemic Control Using a Nonlinear Adaptive Strategy
- Abstract
- 1: Introduction
- 2: Related Research Work
- 3: Dynamic Model of Hepatitis C Virus Epidemic
- 4: Nonlinear Adaptive Controller Formulation for Epidemiology of HCV
- 5: Results and Discussion
- 6: Conclusion
- Appendix: Barbalat's Lemma
- Chapter 2: Integral Sliding Mode Control of Immune Response for Kidney Transplantation
- Abstract
- 1: Introduction
- 2: Mathematical Model of Transplant Recipients
- 3: Control Scheme
- 4: Simulation Results
- 5: Conclusion Remarks
- Chapter 3: Smart Drug Delivery Systems
- Abstract
- 1: Introduction
- 2: pH-Responsive Drug Delivery Systems
- 3: Redox-Responsive Drug Delivery Systems
- 4: Thermoresponsive Drug Delivery Systems
- 5: Hypoxia-Responsive Drug Delivery Systems
- 6: Other External Stimuli-Responsive Systems
- 7: Conclusions
- Chapter 4: Polymeric Transdermal Drug Delivery Systems
- Abstract
- 1: Introduction
- 2: Skin Structure and Wounds
- 3: Wound Dressings
- 4: Different Drug Types
- 5: Thermodynamic/Kinetic of Drug Delivery Systems
- 6: Polymeric Transdermal Drug Delivery Systems
- 7: Concluding Remarks
- Chapter 5: Stimuli-Responsive Polymers as Smart Drug Delivery Systems
- Abstract
- 1: Introduction
- 2: Polymers as Responsive Drug Delivery Systems
- 3: Future Trend and Conclusion
- Chapter 6: Efficacy of Polymer-Based Wound Dressings in Chronic Wounds
- Abstract
- Acknowledgments
- 1: Introduction
- 2: Types of Wounds and Healing Phase
- 3: Wound Dressings
- 4: Conclusion
- Chapter 7: Recent Progress of Transdermal Drug Delivery Systems for Biomedical Applications
- Abstract
- 1: Introduction
- 2: Skin Morphology
- 3: Skin Penetration
- 4: Components of Transdermal Drug Delivery Systems
- 5: Approaches for Developing TDDS
- 6: Evaluation of Transdermal DDS
- 7: Transdermal Drug Delivery Systems in the Management of Diseases
- 8: Miscellaneous Bio Medical Applications of TDDS
- 9: Conclusion
- Chapter 8: Towards the Development of Delivery Systems of Bioactive Compounds With Eyes Set on Pharmacokinetics
- Abstract
- Acknowledgments
- 1: Introduction
- 2: Drug Delivery Systems
- 3: Issues on the Pharmacology of Natural Compounds
- 4: Pharmacokinetic Analysis
- 5: Study Models and Application in Dermal Delivery
- 6: Conclusions
- Chapter 9: Nanofiber: An Immerging Novel Drug Delivery System
- Abstract
- 1: Introduction
- 2: Nanofiber as Prolonged-Drug Delivery System
- 3: Clinical Applicability Challenges
- 4: Future Perspective
- 5: Conclusion
- Chapter 10: Molecular Dynamics Simulations on Drug Delivery Systems
- Abstract
- Acknowledgments
- 1: Introduction
- 2: Polymer Composites/Nanocomposites as Drug Delivery Systems
- 3: Graphene and Its Derivatives as Drug Delivery Systems
- 4: Carbon Nanotubes and Their Derivatives as Drug Delivery Systems
- 5: Fullerenes as Drug Delivery Systems
- 6: DNAs as Drug Delivery Systems
- 7: Peptides and Cell Penetrating Peptides as Drug Delivery Systems
- 8: Proteins as Drug Delivery Systems
- 9: Nanoparticles as Drug Delivery Systems
- 10: Liposomes as Drug Delivery Systems
- 11: Micelles as Drug Delivery Systems
- 12: Conclusion
- Chapter 11: Nanoparticle Drug Delivery: An Advanced Approach for Highly Competent and Multifunctional Therapeutic Treatment
- Abstract
- Acknowledgments
- 1: Introduction
- 2: Background of Nanoparticles in Human History and Drug Development
- 3: Types of Nanoparticles Used for Therapeutic Treatment
- 4: Toxicological Profile of Nanoparticles
- 5: Conclusion and Future Development
- Chapter 12: Targeted Drug Delivery: Advancements, Applications, and Challenges
- Abstract
- 1: Introduction
- 2: Active Targeting
- 3: Passive Targeting
- 4: Comparison of Active and Passive Targeting
- 5: Conclusion
- Chapter 13: Strategies-Based Intrathecal Targeted Drug Delivery System for Effective Therapy, Modeling, and Controlled Release Action
- Abstract
- 1: Introduction
- 2: Strategies for Intrathecal Drug Delivery
- 3: Emerging Trends in Intrathecal Drug Delivery
- 4: Conclusion
- Chapter 14: Biopolymer-Based Hydrogel Wound Dressing
- Abstract
- Acknowledgments
- Declaration of Interest
- 1: Introduction
- 2: Wound Dressing and Its Ideal Properties
- 3: Wound Dressing Based on Biopolymers
- 4: Clinical Application
- 5: Future Perspective
- Chapter 15: Novel Controlled Release Pulmonary Drug Delivery Systems: Current updates and Challenges
- Abstract
- 1: Introduction
- 2: Background
- 3: Methods
- 4: Nanocarrier Drug Delivery Systems
- 5: Drug Delivery Approaches for Pulmonary Respiratory Disease
- 6: Future Directions
- 7: Conclusion
- Chapter 16: Nanoparticle Formulations and Delivery Strategies for Sustained Drug Release in the Lungs
- Abstract
- 1: Introduction
- 2: Benefits and Drawbacks of the Pulmonary Route Over Other Administration Routes
- 3: Marketed Inhalable Products and Patient Compliance
- 4: The Role of Formulation for Controlled PDD
- 5: The Role of Inhaler Devices for Controlled PDD
- 6: Nanobiotechnology Solutions Against Asthma and COPD
- 7: Nanobiotechnology Solutions Against Pulmonary Infections and Cancer
- 8: Conclusions
- Chapter 17: Current Perspectives on Mycosynthesis of Nanoparticles and Their Biomedical application
- Abstract
- Acknowledgment
- Conflict of Interest
- 1: Introduction
- 2: Microbial Green synthesis: A Novel and Eco-friendly Approach
- 3: Mycosynthesis of Various NPs and Their Biomedical Applications
- 4: Conclusion and Future Prospects
- Chapter 18: Solid Oral Controlled-Release Formulations
- Abstract
- 1: Introduction
- 2: Need for Controlled-Release Dosage Forms
- 3: Terminologies Used for Describing Controlled-Release Formulations
- 4: Polymers used in Controlled-Release Systems
- 5: Types of Controlled-Release Drug Delivery Systems
- 6: Drug Release Characterization From Controlled-Drug Delivery Systems
- 7: Conclusion
- 8: Future Prospects
- Chapter 19: Advanced Solid Oral Controlled-Release Formulations
- Abstract
- 1: Introduction
- 2: Gastro-Retentive Drug Delivery Systems
- 3: Colon-Targeted Drug Delivery Systems
- 4: Feedback-Regulated Systems
- 5: Enteric Drug Delivery Systems
- 6: Osmotic Drug Delivery Systems
- 7: 3D Printing-Based Controlled-Release Formulations
- 8: Ultra-Long Acting Formulations
- 9: Patented Technologies
- 10: Future Perspective
- 11: Conclusion
- Chapter 20: Mucoadhesive Polymers: Gateway to Innovative Drug Delivery
- Abstract
- 1: Introduction
- 2: Mechanism of Mucoadhesion
- 3: Mucus Gel Layer
- 4: Evaluation of Mucoadhesive Properties
- 5: Mucoadhesive Polymers
- 6: Factors Affecting Mucoadhesion
- 7: Mucoadhesive Drug Delivery Systems
- 8: Marketed Mucoadhesive Products
- 9: Future Perspectives of Mucoadhesive Drug Delivery Systems
- 10: Conclusion
- Index
- Edition: 1
- Published: February 6, 2021
- No. of pages (Paperback): 408
- No. of pages (eBook): 408
- Imprint: Academic Press
- Language: English
- Paperback ISBN: 9780128211854
- eBook ISBN: 9780128211953
AT
Ahmad Taher Azar
Ahmad Azar is a Research Associate Professor at the Prince Sultan University, Riyadh, Kingdom Saudi Arabia. He is also an associate professor at the Faculty of Computers and Artificial intelligence, in Benha University, Egypt. He is the Editor in Chief of the International Journal of System Dynamics Applications (IJSDA), International Journal of Service Science, Management, Engineering, and Technology (IJSSMET), and International Journal of Intelligent Engineering Informatics (IJIEI), among others. He is currently Associate Editor of ISA Transactions, Elsevier, and the IEEE systems journal. Dr. Azar works in the areas of control theory & applications, process control, chaos control and synchronization, nonlinear control, renewable energy, computational intelligence.
Affiliations and expertise
Research Associate Professor, Prince Sultan University, Riyadh, Kingdom Saudi ArabiaAssociate Professor, Faculty of Computers and Artificial intelligence, Benha University, EgyptRead Modeling and Control of Drug Delivery Systems on ScienceDirect