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Miller’s Basics of Anesthesia
- 8th Edition - July 5, 2022
- Editor: Manuel Pardo
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 7 9 6 7 7 - 4
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 7 9 6 7 8 - 1
Long regarded as the undisputed leading text of its kind, Miller’s Basics of Anesthesia provides comprehensive yet concise coverage of both basic science and clinical topics in… Read more
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Request a sales quoteFeatures a reader-friendly format with color-coded section tabs, easy-to-read chapters, and a concise writing style, along with color patterns in every chapter for quick navigation.
Contains new chapters on Clinician Well-Being, Perioperative Point-of-Care Ultrasound, Environmental Impact of Anesthetics, and Perioperative Medicine.
Covers key topics such as anesthesia neurotoxicity, palliative care, sleep medicine, trauma, and much more.
Includes high-quality images that offer a detailed visual understanding of complex topics, while numerous figures and tables condense material for easier retention and review.
Shares the knowledge and experience of renowned anesthesia expert Dr. Manuel C. Pardo, Jr. and a team of more than 80 global contributing authors.
Serves both as an initial learning resource and a useful tool for solidifying the essential “must know” information and reviewing core knowledge for maintenance of certification.
Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
- Cover Image
- Title Page
- Copyright
- Dedication
- Contributors
- Preface
- Foreword
- Table of Contents
- Section I Introduction
- Chapter 1 Scope of Anesthesia Practice
- ANESTHESIOLOGY AS A MULTIDISCIPLINARY SPECIALTY
- PERIOPERATIVE PATIENT CARE
- ANESTHESIA WORKFORCE
- TRAINING AND CERTIFICATION IN ANESTHESIOLOGY
- QUALITY AND SAFETY
- VALUE-BASED CARE
- FUTURE OF ANESTHESIA CARE
- ACKNOWLEDGMENT
- REFERENCES
- Chapter 2 Learning Anesthesia
- COMPETENCIES, MILESTONES, AND ENTRUSTABLE PROFESSIONAL ACTIVITIES
- STRUCTURED APPROACH TO ANESTHESIA CARE
- LEARNING STRATEGIES
- REFERENCES
- Chapter 3 Clinician Well-Being
- DEFINING TERMS
- WHY WELL-BEING IS IMPORTANT
- FACTORS AFFECTING CLINICIAN WELL-BEING
- MENTAL HEALTH
- INTERVENTIONS TO IMPROVE WELL-BEING
- REFERENCES
- Section II Pharmacology and Physiology
- Chapter 4 Basic Pharmacologic Principles
- PHARMACOKINETIC PRINCIPLES
- PHARMACODYNAMIC PRINCIPLES
- SPECIAL POPULATIONS
- SUMMARY
- REFERENCES
- Chapter 5 Clinical Cardiac and Pulmonary Physiology
- HEMODYNAMICS
- CARDIAC REFLEXES
- CORONARY BLOOD FLOW
- PULMONARY CIRCULATION
- PULMONARY GAS EXCHANGE
- PULMONARY MECHANICS
- CONTROL OF BREATHING
- INTEGRATION OF THE HEART AND LUNGS
- REFERENCES
- Chapter 6 Autonomic Nervous System
- ANATOMY OF THE AUTONOMIC NERVOUS SYSTEM
- ADRENERGIC PHARMACOLOGY
- SELECTIVE α-ADRENERGIC RECEPTOR AGONISTS
- β2-ADRENERGIC RECEPTOR AGONISTS
- α-ADRENERGIC RECEPTOR ANTAGONISTS
- β-ADRENERGIC ANTAGONISTS
- CHOLINERGIC PHARMACOLOGY
- REFERENCES
- Chapter 7 Inhaled Anesthetics
- HISTORY
- CHEMICAL AND PHYSICAL PROPERTIES
- UPTAKE AND DISTRIBUTION IN THE BODY
- MINIMUM ALVEOLAR CONCENTRATION
- MECHANISMS
- ORGAN SYSTEM EFFECTS
- UNIQUE ISSUES WITH NITROUS OXIDE
- TOXICITY AND ADVERSE EVENTS
- METABOLISM, ELIMINATION, AND RECOVERY
- ENVIRONMENTAL CONSIDERATIONS (ALSO SEE CHAPTER 49)
- REFERENCES
- Chapter 8 Intravenous Anesthetics
- WHY INTRAVENOUS ANESTHETICS?
- GABAA RECEPTOR AGONISM
- PROPOFOL
- BARBITURATES
- BENZODIAZEPINES
- KETAMINE
- ETOMIDATE
- DEXMEDETOMIDINE
- ACKNOWLEDGMENTS
- REFERENCES
- Chapter 9 Opioids
- BASIC PHARMACOLOGY
- CLINICAL PHARMACOLOGY
- CLINICAL APPLICATION
- EMERGING DEVELOPMENTS
- ACKNOWLEDGMENT
- REFERENCES
- Chapter 10 Local Anesthetics
- HISTORY
- NERVE CONDUCTION
- LOCAL ANESTHETIC ACTIONS ON SODIUM CHANNELS
- DIFFERENTIAL LOCAL ANESTHETIC BLOCKADE
- SPREAD OF LOCAL ANESTHESIA AFTER INJECTION
- PHARMACOKINETICS
- ADVERSE EFFECTS
- SPECIFIC LOCAL ANESTHETICS
- WHEN LOCAL ANESTHESIA FAILS
- FUTURE LOCAL ANESTHETICS
- CONCLUSIONS
- ACKNOWLEDGMENTS
- REFERENCES
- Chapter 11 Neuromuscular Blocking and Reversal Agents
- INTRODUCTION
- THE NEUROMUSCULAR JUNCTION
- STRUCTURE–ACTIVITY RELATIONSHIPS
- DEPOLARIZING NEUROMUSCULAR BLOCKING AGENTS: SUCCINYLCHOLINE
- NONDEPOLARIZING NEUROMUSCULAR BLOCKING AGENTS
- MONITORING THE EFFECTS OF NONDEPOLARIZING NEUROMUSCULAR BLOCKING AGENTS
- ANTAGONISM OF RESIDUAL NEUROMUSCULAR BLOCK
- SUMMARY
- ACKNOWLEDGMENT
- REFERENCES
- Chapter 12 Anesthetic Neurotoxicity
- ANESTHETIC DRUGS AS A CAUSE FOR NEURODEGENERATION AND LONG-TERM NEUROCOGNITIVE DEFICITS
- CLINICAL EVIDENCE FOR NEUROTOXICITY
- INTRAOPERATIVE COURSE AND NEUROCOGNITIVE OUTCOMES
- CONCLUSION
- REFERENCES
- Section III Preoperative Preparation and Intraoperative Management
- Chapter 13 Preoperative Evaluation
- HISTORY AND PHYSICAL EXAMINATION
- PREOPERATIVE EVALUATION OF COMMON COEXISTING DISEASES
- PREOPERATIVE TESTING
- RISK ASSESSMENT
- MEDICATION MANAGEMENT
- NPO GUIDELINES
- INFORMED CONSENT FOR ANESTHESIA
- PREOPERATIVE EVALUATION CLINICS
- ACKNOWLEDGMENT
- REFERENCES
- Chapter 14 Choice of Anesthetic Technique
- TYPES OF ANESTHESIA
- CHOOSING AN APPROPRIATE ANESTHETIC TECHNIQUE
- PRACTICAL ASPECTS OF ANESTHESIA CHOICE
- ACKNOWLEDGMENT
- REFERENCES
- Chapter 15 Anesthesia Delivery Systems
- THE ANESTHESIA WORKSTATION
- FUNCTIONAL ANATOMY OF THE ANESTHESIA WORKSTATION
- ANESTHETIC BREATHING CIRCUITS
- ANESTHESIA VENTILATORS
- SCAVENGING SYSTEMS
- CHECKING YOUR ANESTHESIA WORKSTATION
- ACKNOWLEDGMENT
- REFERENCES
- Chapter 16 Airway Management
- ANATOMY AND PHYSIOLOGY OF THE UPPER AIRWAY
- AIRWAY ASSESSMENT
- AIRWAY MANAGEMENT TECHNIQUES
- INVASIVE AIRWAY ACCESS
- COMPLICATIONS
- AIRWAY MANAGEMENT IN INFANTS AND CHILDREN (ALSO SEE CHAPTER 34)
- ACKNOWLEDGMENT
- REFERENCES
- Chapter 17 Spinal, Epidural, and Caudal Anesthesia
- PRINCIPLES
- PRACTICE
- EVIDENCE
- ANATOMY
- MECHANISM OF ACTION
- PHYSIOLOGIC EFFECTS
- INDICATIONS
- CONTRAINDICATIONS
- SPINAL ANESTHESIA
- EPIDURAL ANESTHESIA
- COMBINED SPINAL-EPIDURAL ANESTHESIA
- CAUDAL ANESTHESIA
- COMPLICATIONS
- REFERENCES
- Chapter 18 Peripheral Nerve Blocks
- INTRODUCTION
- ULTRASOUND BASICS
- CERVICAL PLEXUS BLOCK
- UPPER EXTREMITY BLOCKS
- LOWER EXTREMITY BLOCKS
- CHEST AND ABDOMEN BLOCKS
- INTRAVENOUS REGIONAL ANESTHESIA (BIER BLOCK)
- REFERENCES
- Chapter 19 Patient Positioning and Associated Risks
- PHYSIOLOGIC ASPECTS OF POSITIONING
- GENERAL POSITIONING PRINCIPLES
- POSITIONING FOR ROBOTIC-ASSISTED SURGERY
- PRESSURE INJURIES
- BITE INJURIES
- PERIPHERAL NERVE INJURIES
- EVALUATION AND TREATMENT OF PERIOPERATIVE NEUROPATHIES
- PERIOPERATIVE EYE INJURY AND VISUAL LOSS
- ANESTHESIA OUTSIDE THE OPERATING ROOM
- CONCLUSION
- REFERENCES
- Chapter 20 Anesthetic Monitoring
- INTRODUCTION
- RESPIRATORY SYSTEM
- CIRCULATORY SYSTEM
- CENTRAL NERVOUS SYSTEM
- PERIPHERAL NERVOUS SYSTEM
- TEMPERATURE
- MAGNETIC RESONANCE IMAGING AND ADVERSE CONDITIONS
- MULTIFUNCTION DISPLAYS AND DECISION SUPPORT
- REFERENCES
- Chapter 21 Point-of-Care Ultrasound
- REVIEW OF ULTRASOUND PHYSICS
- ULTRASOUND TRANSDUCERS
- PREPARING FOR THE EXAMINATION
- BASIC CARDIAC ULTRASOUND
- PULMONARY ULTRASOUND
- ABDOMINAL ULTRASOUND
- CONCLUSIONS AND FUTURE DIRECTIONS
- REFERENCES
- Chapter 22 Acid–Base Balance and Blood Gas Analysis
- DEFINITIONS
- REGULATION OF THE HYDROGEN ION CONCENTRATION
- ANALYSIS OF ARTERIAL BLOOD GASES
- DIFFERENTIAL DIAGNOSIS OF ACID–BASE DISTURBANCES
- OTHER INFORMATION PROVIDED BY ANALYSIS OF ARTERIAL BLOOD GASES AND pH
- REFERENCES
- Chapter 23 Hemostasis
- INTRODUCTION
- NORMAL HEMOSTASIS
- BLEEDING DISORDERS
- PROTHROMBOTIC STATES
- LABORATORY EVALUATION OF HEMOSTASIS
- ANTITHROMBOTIC AND PROCOAGULANT DRUGS
- PERIOPERATIVE MANAGEMENT OF ANTITHROMBOTIC THERAPY
- CONCLUSION
- ACKNOWLEDGMENT
- REFERENCES
- Chapter 24 Fluid Management
- INTRODUCTION
- PHYSIOLOGY OF FLUID BALANCE
- FLUID REPLACEMENT SOLUTIONS
- HEMODYNAMIC MONITORING FOR FLUID RESPONSIVENESS
- PERIOPERATIVE FLUID STRATEGIES FOR OPTIMAL VOLUME STATUS
- CONCLUSIONS
- ACKNOWLEDGMENT
- REFERENCES
- Chapter 25 Blood Therapy
- BLOOD BANKING ESSENTIALS
- BLOOD COMPONENTS
- PATIENT BLOOD MANAGEMENT AND THE DECISION TO TRANSFUSE RED BLOOD CELLS
- COMPLICATIONS OF BLOOD THERAPY
- AUTOLOGOUS BLOOD TRANSFUSIONS
- CONCLUSIONS AND FUTURE DIRECTIONS
- REFERENCES
- Section IV Special Anesthetic Considerations
- Chapter 26 Cardiovascular Disease
- CORONARY ARTERY DISEASE
- VALVULAR HEART DISEASE
- DISTURBANCES OF CARDIAC CONDUCTION AND RHYTHM
- HEART FAILURE
- HYPERTROPHIC CARDIOMYOPATHY
- PULMONARY HYPERTENSION
- CARDIAC TAMPONADE
- ANEURYSMS OF THE AORTA
- CARDIOPULMONARY BYPASS
- ACKNOWLEDGMENTS
- REFERENCES
- Chapter 27 Chronic Pulmonary Disease
- INTRODUCTION
- ASTHMA
- CHRONIC OBSTRUCTIVE PULMONARY DISEASE
- INTERSTITIAL LUNG DISEASE
- CYSTIC FIBROSIS
- OBSTRUCTIVE SLEEP APNEA (ALSO SEE CHAPTER 48)
- PULMONARY HYPERTENSION
- ANESTHESIA FOR LUNG RESECTION
- MEDIASTINOSCOPY
- MEDIASTINAL MASSES
- REFERENCES
- Chapter 28 Renal, Liver, and Biliary Tract Disease
- RENAL DISEASE
- LIVER DISEASE
- DISEASES OF THE BILIARY TRACT
- REFERENCES
- Chapter 29 Nutritional, Gastrointestinal, and Endocrine Disease
- NUTRITIONAL DISORDERS
- GASTROINTESTINAL DISORDERS
- ENDOCRINE DISORDERS
- REFERENCES
- Chapter 30 Central Nervous System Disease
- NEUROANATOMY
- NEUROPHYSIOLOGY
- INTRACRANIAL PRESSURE AND BRAIN RELAXATION
- NEUROPROTECTION
- NEUROPHYSIOLOGIC MONITORING
- ANESTHESIA FOR NEUROSURGERY
- COMMON CLINICAL CASES
- REFERENCES
- Chapter 31 Ophthalmology and Otolaryngology
- OPHTHALMOLOGY
- OTOLARYNGOLOGY
- REFERENCES
- Chapter 32 Orthopedic Surgery
- RHEUMATOLOGIC DISORDERS
- SPINE SURGERY
- SURGERY IN THE SITTING POSITION
- FRACTURED HIP
- TOTAL JOINT REPLACEMENT
- REFERENCES
- Chapter 33 Obstetrics
- PHYSIOLOGIC CHANGES IN PREGNANT WOMEN
- PHYSIOLOGY OF THE UTEROPLACENTAL CIRCULATION
- STAGES OF LABOR
- ANATOMY OF LABOR PAIN
- METHODS OF LABOR ANALGESIA
- NEURAXIAL TECHNIQUES
- CONTRAINDICATIONS OF NEURAXIAL ANESTHESIA
- COMPLICATIONS OF NEURAXIAL ANESTHESIA
- ANESTHESIA FOR CESAREAN DELIVERY
- ABNORMAL PRESENTATIONS AND MULTIPLE BIRTHS
- HYPERTENSIVE DISORDERS OF PREGNANCY
- HEMORRHAGE IN PREGNANT WOMEN
- AMNIOTIC FLUID EMBOLISM
- ANESTHESIA FOR NONOBSTETRIC SURGERY DURING PREGNANCY
- DIAGNOSIS AND MANAGEMENT OF FETAL DISTRESS
- EVALUATION OF THE NEONATE AND NEONATAL RESUSCITATION
- REFERENCES
- Chapter 34 Pediatrics
- DEVELOPMENTAL PHYSIOLOGY
- PHARMACOLOGIC DIFFERENCES
- FLUIDS AND ELECTROLYTES
- TRANSFUSION THERAPY
- PEDIATRIC AIRWAY
- ANESTHETIC CONSIDERATIONS
- MEDICAL AND SURGICAL DISEASES AFFECTING THE NEONATE
- CONGENITAL HEART DISEASE
- SPECIAL ANESTHETIC CONSIDERATIONS
- REFERENCES
- Chapter 35 Geriatrics
- INTRODUCTION
- THE PHYSIOLOGIC CHANGES OF AGING
- PHARMACOLOGIC CONSIDERATIONS
- PREOPERATIVE ASSESSMENT AND RISK MANAGEMENT
- INTRAOPERATIVE CONSIDERATIONS
- POSTOPERATIVE MANAGEMENT
- CHRONIC PAIN IN THE ELDERLY
- PERIOPERATIVE NEUROCOGNITIVE DISORDERS
- SUMMARY
- ACKNOWLEDGMENT
- REFERENCES
- Chapter 36 Organ Transplantation
- CONSIDERATIONS FOR ORGAN TRANSPLANTATION
- KIDNEY TRANSPLANTATION
- LIVER TRANSPLANTATION
- HEART TRANSPLANTATION
- LUNG TRANSPLANTATION
- PANCREAS TRANSPLANTATION
- CONCLUSION
- REFERENCES
- Chapter 37 Outpatient Anesthesia
- INTRODUCTION
- PATIENT SELECTION
- SURGERIES AND PROCEDURES
- PREOPERATIVE EVALUATION
- ANESTHETIC TECHNIQUES
- POSTOPERATIVE CARE
- QUALITY IMPROVEMENT
- ADVANCES AND NEW TRENDS IN OUTPATIENT ANESTHESIA
- CONCLUSION
- REFERENCES
- Chapter 38 Anesthesia for Procedures in NonOperating Room Locations
- CHARACTERISTICS OF NORA LOCATIONS
- SAFETY AND CONCERNS IN RADIOLOGY SUITES
- MAGNETIC RESONANCE IMAGING
- ANESTHESIA FOR NONINVASIVE IMAGING PROCEDURES
- INTERVENTIONAL RADIOLOGY
- ENDOSCOPY AND ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY
- CATHETER-BASED CARDIOLOGY PROCEDURES
- ELECTROCONVULSIVE THERAPY
- REFERENCES
- Section V The Recovery Period
- Chapter 39 Postanesthesia Recovery
- ADMISSION TO THE POSTANESTHESIA CARE UNIT
- EARLY POSTOPERATIVE PHYSIOLOGIC CHANGES
- UPPER AIRWAY OBSTRUCTION
- PULMONARY EDEMA IN THE PACU
- MONITORING AND TREATMENT OF HYPOXEMIA
- HEMODYNAMIC INSTABILITY
- RENAL DYSFUNCTION
- POSTOPERATIVE HYPOTHERMIA AND SHIVERING
- POSTOPERATIVE NAUSEA AND VOMITING
- DELIRIUM
- DELAYED AWAKENING
- DISCHARGE CRITERIA
- POSTANESTHESIA SCORING SYSTEMS
- REFERENCES
- Chapter 40 Perioperative Pain Management
- COMMON TERMINOLOGY
- NEUROBIOLOGY OF PAIN
- ANALGESIC DELIVERY SYSTEMS
- SYSTEMIC THERAPY
- NEURAXIAL ANALGESIA (ALSO SEE CHAPTER 17)
- SURGICAL SITE (INCISION) INFILTRATION
- INTRAARTICULAR ADMINISTRATION
- PARAVERTEBRAL BLOCKS
- PERIPHERAL NERVE BLOCK
- REGIONAL ANALGESIA
- TRANSVERSUS ABDOMINIS PLANE BLOCK
- REFERENCES
- Section VI Consultant Anesthetic Practice
- Chapter 41 Critical Care Medicine
- ICU DEFINITIONS, INTERPROFESSIONAL CARE, AND PHYSICIAN STAFFING
- ORGAN FAILURE AND SUPPORT
- A-F BUNDLE
- ACKNOWLEDGMENT
- REFERENCES
- Chapter 42 Perioperative Medicine
- INTRODUCTION
- THE PERIOPERATIVE MEDICINE CONSULTANT
- IMPROVING PERIOPERATIVE OUTCOMES AND OPERATIONALIZING PERIOPERATIVE MEDICINE
- VALUE-ADDED PREOPERATIVE SCREENING AND TESTING
- MEDICAL MANAGEMENT OF THE MOST COMMON COMORBIDITIES
- PSYCHOLOGICAL STATE: ASSESSMENT AND INTERVENTIONS
- COGNITIVE SCREENING AND INTERVENTIONS (ALSO SEE CHAPTER 35)
- HEALTH LITERACY AND SHARED DECISION MAKING
- OTHER OPPORTUNITIES TO IMPROVE PERIOPERATIVE OUTCOMES
- FUTURE DIRECTIONS IN PERIOPERATIVE MEDICINE: SOCIAL DETERMINANTS OF HEALTH
- REFERENCES
- Chapter 43 Anesthesia for Trauma
- INTRODUCTION
- INITIAL MANAGEMENT
- INTRAOPERATIVE MANAGEMENT
- SPECIAL CONSIDERATIONS
- ACKNOWLEDGMENT
- REFERENCES
- Chapter 44 Chronic Pain Management
- INTRODUCTION
- CHRONIC PAIN FOUNDATIONS
- PAINFUL CONDITIONS: SPINE
- PAINFUL CONDITIONS: NEUROPATHIC PAIN
- PAINFUL CONDITIONS: CHRONIC POSTSURGICAL PAIN
- PAIN CONDITIONS: ADDITIONAL GENERATORS
- PSYCHOLOGICAL TREATMENT PILLAR: CATASTROPHIZING
- PHYSICAL MEDICINE TREATMENT PILLAR
- PHARMACOLOGIC TREATMENT PILLAR
- PROCEDURAL TREATMENT PILLAR
- NEUROMODULATION: ADVANCED INTERVENTIONAL PAIN MEDICINE
- SUMMARY
- ACKNOWLEDGMENT
- REFERENCES
- Chapter 45 Cardiopulmonary Resuscitation
- INTRODUCTION
- EVIDENCE BASED
- PRINCIPLES OF MANAGEMENT
- REFERENCES
- Chapter 46 Quality and Patient Safety in Anesthesia Care
- INTRODUCTION
- DEFINITIONS: QUALITY VERSUS SAFETY
- SPECIFIC APPROACHES TO ANESTHESIA SAFETY
- FROM SAFETY TO QUALITY: MAKING ANESTHESIA BOTH SAFER AND BETTER
- TOOLS FOR IMPROVING LOCAL OUTCOMES
- SUMMARY
- REFERENCES
- Chapter 47 Palliative Care
- INTRODUCTION
- WHAT DO PALLIATIVE CARE TEAMS DO?
- PALLIATIVE CARE AND PAIN
- CHALLENGES IN THE PALLIATIVE CARE PATIENT
- PERIOPERATIVE MANAGEMENT OF THE PALLIATIVE CARE PATIENT
- CONCLUSION
- REFERENCES
- Chapter 48 Sleep Medicine and Anesthesia
- INTRODUCTION
- BASIC SLEEP PHYSIOLOGY
- GENERAL ANESTHESIA
- OTHER AROUSAL STATES
- SLEEP AND ANESTHESIA STATES
- FUNCTIONAL NEUROANATOMY OF SLEEP AND AROUSAL PATHWAYS
- SLEEP-DISORDERED BREATHING OR SLEEP-RELATED BREATHING DISORDERS
- OBSTRUCTIVE SLEEP APNEA
- CONCLUSION
- REFERENCES
- Chapter 49 Anesthesia and Environmental Health
- HEALTH, HEALTH CARE, AND CLIMATE CHANGE
- ENVIRONMENTAL IMPACT OF ANESTHESIA GASES
- OCCUPATIONAL HAZARDS OF INHALED ANESTHETICS
- LOW-FLOW ANESTHESIA
- CLOSED-CIRCUIT ANESTHESIA
- CO2 ABSORBENTS
- WASTE ANESTHETIC GAS SCAVENGING SYSTEMS
- ENVIRONMENTAL IMPACT OF PROPOFOL
- DRUG WASTE
- ENVIRONMENTAL IMPACT OF OPERATING ROOM PRACTICES
- SUMMARY
- REFERENCES
- Index
- No. of pages: 951
- Language: English
- Edition: 8
- Published: July 5, 2022
- Imprint: Elsevier
- Hardback ISBN: 9780323796774
- eBook ISBN: 9780323796781
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