Micro/Nanofluidics and Lab-on-Chip Based Emerging Technologies for Biomedical and Translational Research Applications - Part A

1st Edition, Volume 186 - January 13, 2022
Editors: Alok Pandya, Vijai Singh
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 9 8 8 9 9 - 5
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 9 8 9 0 0 - 8

Micro/Nanofluidics and Lab-on-Chip Based Emerging Technologies for Biomedical and Translational Research Applications, Volume 185, Part A represents the collation of chapters… Read more

Micro/Nanofluidics and Lab-on-Chip Based Emerging Technologies for Biomedical and Translational Research Applications - Part A

Purchase options

ROBOTICS & AUTOMATION

Empowering Progress

Up to 25% off Essentials Robotics and Automation titles

Explore now

Image with Robotics & Automation book covers

Institutional subscription on ScienceDirect

Request a sales quote

Micro/Nanofluidics and Lab-on-Chip Based Emerging Technologies for Biomedical and Translational Research Applications, Volume 185, Part A represents the collation of chapters written by eminent scientists worldwide. Chapters in this updated release include An introduction to microfluidics and their applications, Design and fabrication of Micro/Nanofluidics devices and systems, Detection and separation of proteins using Micro/Nanofluidics devices, Micro/Nanofluidics devices for DNA/RNA detection and separation, Paper based microfluidics a forecast towards the most affordable and rapid point-of-care devices, Paper based micro/Nanofluidics devices for biomedical applications, Advances of Microfluidics Devices and their Applications in Personalized Medicine, and much more.

Additional chapters cover Microfluidics for single cell analysis, Fluorescence Based Miniaturized Microfluidic and Nanofluidic Systems for Biomedical Applications, Active Matter Dynamics in Confined Microfluidic Environments, Challenges and opportunities in micro/nanofluidics and lab-on-a-chip, and Paper-microfluidic signal-enhanced immunoassays.

Cover image
Title page
Table of Contents
Copyright
Contributors
Preface
Chapter One: An introduction to microfluidics and their applications
Abstract
1: Introduction
2: Type of micro/nanofluidics
3: Design and fabrication of microfluidics devices
4: Paper based microfluidics
5: Application of microfluidics devices
6: Conclusion and future remarks
Acknowledgments
Chapter Two: Design and fabrication of micro/nanofluidics devices and systems
Abstract
1: Introduction
2: Theory of micro/nanofluidics
3: Fabrication of micro/nanofluidic devices
4: Design thinking approach for micro/nanofluidics
5: Outlook
Chapter Three: Detection and separation of proteins using micro/nanofluidics devices
Abstract
1: Introduction
2: Protein separation using microfluidics system/devices
3: Conclusion
Chapter Four: Micro/nanofluidic devices for DNA/RNA detection and separation
Abstract
1: Introduction
2: Separation of nucleic acid using NF and MF
3: Detection of nucleic acid using NF and MF using different fabrication techniques
4: Future prospects
Acknowledgments
Chapter Five: Paper based microfluidics: A forecast toward the most affordable and rapid point-of-care devices
Abstract
1: Introduction and historical perspective of paper-based microfluidic devices
2: Fabrication methods
3: Fluid flow control and liquid handling
4: Applications of paper-based microfluidic devices
5: Current limitations and future works
6: Conclusion and final thoughts
Acknowledgment
Chapter Six: Paper based micro/nanofluidics devices for biomedical applications
Abstract
1: Importance of paper as a diagnostic device
2: Paper as a sample pretreatment platform in clinical diagnosis
3: Paper microfluidic diagnostic devices
4: Dipstick paper biosensors
5: Lateral flow assay (LFA)
6: MicroPAD (μPAD)
7: Fabrications of paper microfluidics
8: Detection techniques
9: Readout devices
10: Biomedical applications
11: Paper nanofluidics
12: Challenges and research gaps
13: Conclusions
14: Future outlook
Acknowledgment
Chapter Seven: Advances in microfluidics devices and its applications in personalized medicines
Abstract
1: Introduction
2: Microfluidics for cancer theranostics
3: Microfluidics for detection of cardiovascular diseases
4: Microfluidics for detection of diabetes
5: Microfluidics for detection of pulmonary disease and therapy
6: Conclusion and future perspectives
Acknowledgments
Chapter Eight: Microfluidics for single cell analysis
Abstract
1: Introduction
2: Design and fabrication of microfluidics devices and chips
3: Droplets-based single cell analysis and their applications
4: Use of microfluidics devices for single cell analysis
5: Conclusion and future remarks
Acknowledgments
Chapter Nine: Fluorescence based miniaturized microfluidic and nanofluidic systems for biomedical applications
Abstract
1: Introduction
2: Microfluidic systems for biomedical applications
3: Nanofluidic systems for biomedical applications
4: Conclusion and future prospects
Acknowledgments
Chapter Ten: Active matter dynamics in confined microfluidic environments
Abstract
Chapter Eleven: Paper-microfluidic signal-enhanced immunoassays
Abstract
1: Introduction and the history of paper-based immunoassays
2: Classification of signal enhancement strategies used in paper-based immunoassays
3: SWOT analysis: Paper-based immunoassays
Chapter Twelve: Challenges and opportunities in micro/nanofluidic and lab-on-a-chip
Abstract
1: Understand micro/nanofluidic (MF/NF)
2: Understand lab-on-a-chip
3: Challenges in designing micro/nanofluidic
4: Challenges in designing lab-on-a-chip device
5: Opportunities in micro/nanofluidic and lab-on-a-chip devices
Acknowledgments
Index

Alok Pandya

Dr. Alok Pandya is an innovator, interdisciplinary researcher, and academic leader specializing in the development of personalized biosensors for point-of-care/need diagnostics and rapid disease detection. His work focuses on developing advanced biosensing technologies for real-time health monitoring. Currently serving as an Associate Professor at the School of Applied Science and Technology, Gujarat Technological University, he brings over 11 years of research experience dedicated to biosensor-driven rapid diagnostics. Before joining GTU, Dr. Pandya spent 8 years as an Assistant Professor at the Institute of Advanced Research (IAR) and 3 years as a Research Associate at Ahmedabad University. He has also been a Visiting Professor at the University of California, San Diego, conducting research on wearable biosensors, and an Entrepreneurial Lead under the US National Science Foundation’s I-Corps™ program, gaining expertise in medical innovation and technology commercialization. A researcher and technologist, Dr. Pandya has published 60+ research articles, authored 5 books & 12+ book chapters, and holds 5 granted patents. His work has secured national and international funding to advance biomedical and forensic diagnostic technologies. He has been honored with prestigious awards, including the SERB-International Research Experience Award, the SERB Young Scientist Award, and the IAR Research Excellence Award. Dr. Pandya has developed cutting-edge biosensing platforms for rapid AMR detection, cardiovascular disease diagnostics, plant pathogen identification, and forensic body fluid analysis. With global research collaborations spanning France, the USA, and India, Dr. Pandya continues to drive innovation in biosensor technology, translating scientific discoveries into real-world applications for precision diagnostics and personalized healthcare.

Affiliations and expertise

School of Applied of Science and Technology, Gujarat Technological technology, Ahmedabad

Vijai Singh

Dr Vijai Singh is a Professor and Dean (Research & Innovation) at School of Sciences, Indrashil University, Rajpur, Mehsana, Gujarat, India. He was an Associate Professor in the Department of Biosciences, School of Sciences, Indrashil University, Rajpur, Mehsana, Gujarat, India. Prior this this, he was an Assistant Professor in the Department of Biological Sciences and Biotechnology at the Institute of Advanced Research, Gandhinagar, India and also an Assistant Professor in the Department of Biotechnology at the Invertis University, Bareilly, India. Prior to that, he was a Postdoctoral Fellow in the Synthetic Biology Group at the Institute of Systems and Synthetic Biology, Paris, France and School of Energy & Chemical Engineering at the Ulsan National Institute of Science and Technology, Ulsan, South Korea. He received his Ph.D. in Biotechnology from the National Bureau of Fish Genetic Resources, Uttar Pradesh Technical University, Lucknow, India with a research focus on the development of molecular and immunoassays for diagnosis of Aeromonas hydrophila. His research interests are focused on building novel biosynthetic pathways for production of medically and industrially important biomolecules. Additionally, his laboratory is working on CRISPR-Cas9 tools for genome editing. He has more than 11 years of research and teaching experience in synthetic biology, metabolic engineering, bioinformatics, microbiology, and industrial microbiology. He has published 100 articles, 70 chapters, 15 books and 3 patents. He serves as an associate editor, editorial board member, and reviewer of several peer-reviewed journals. He is also a member of the Board of Study and Academic Council of Indrashil University and is the Member Secretary of the Institutional Biosafety Committee (IBSC) at the same University.

Affiliations and expertise

Department of Biosciences, School of Science, Indrashil University, Rajpur, Mehsana, India

Life Sciences

Physical Sciences & Engineering

Social Sciences & Humanities

Health