Micro- and Nanoengineered Gum-Based Biomaterials for Drug Delivery and Biomedical Applications
- 1st Edition - January 21, 2022
- Imprint: Elsevier
- Editors: Sougata Jana, Subrata Jana
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 9 0 9 8 6 - 0
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 0 9 8 7 - 7
Micro- and Nanoengineered Gum-Based Biomaterials for Drug Delivery and Biomedical Applications focuses on micro- and nanotechnology in gums and biopolymers as drug and biomolecule… Read more
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Request a sales quoteMicro- and Nanoengineered Gum-Based Biomaterials for Drug Delivery and Biomedical Applications focuses on micro- and nanotechnology in gums and biopolymers as drug and biomolecule carriers and their applications in biomedicine. Currently, natural gums and polymers are widely utilized as biocarrier systems, to deliver drugs and biomolecules to the target site, for prolonged release and the desired therapeutic effect. Natural gums and polymers are important because they are easily available from natural sources and are characteristically biodegradable, biocompatible, and nontoxic. Natural gums and polymers are also chemically modified with other polymers, in the presence of cross-linking agents, to develop scaffolds, matrices, composites, and interpenetrating polymer networks using micro- and nanotechnology. The book also discusses biological applications, such as gene delivery, cancer therapy, tissue engineering, bioimaging, and theranostics.
This book is an important reference source for biomaterials scientists, biomedical engineers, and pharmaceutical scientists, who are looking to increase their understanding of how micro- and nanoengineered biomaterials are being used to create more efficient gum-based drug delivery systems.
- Explains how micro- and nanoengineering is being used to make a variety of gum types more effective as nanocarriers.
- Explores the major biomedical applications of various gum classes.
- Assesses the major challenges of using micro- and nanotechnologies in gum-based biomedical systems.
Materials scientists and engineers.
- Cover
- Title page
- Table of Contents
- Copyright
- Contributors
- Editors' biography
- Preface
- Chapter 1: Nanomedicine approaches and strategies for gum-based stealth nanocarriers
- Abstract
- 1.1: Introduction
- 1.2: Need for stealth nanocarriers
- 1.3: Hydrophilic polymers as shielding agent for nanocarriers
- 1.4: Gum-based stealth nanocarriers: An alternative approach for transportation of payloads to targeted sites
- 1.5: Concluding remarks
- References
- Chapter 2: Micro- and nanoscale drug delivery systems based on xanthan gum hydrogels
- Abstract
- 2.1: Introduction
- 2.2: Homopolymeric XG-based hydrogels
- 2.3: Copolymeric XG-based hydrogels
- 2.4: XG-based nanocomposite hydrogels
- 2.5: Drug delivery potential of xanthan gum hydrogels as nano- and microcarriers for different routes of administration
- 2.6: Concluding remarks
- References
- Chapter 3: Chitosan-based nanoengineered drug delivery system
- Abstract
- 3.1: Introduction
- 3.2: Drug delivery applications of chitosan-based nanoengineered systems
- 3.3: Conclusions
- References
- Chapter 4: Pectin-based micro- and nanomaterials in drug delivery
- Abstract
- 4.1: Introduction
- 4.2: Properties of pectin
- 4.3: Pectin extraction
- 4.4: Modification of pectin
- 4.5: Pectin in biomedical applications
- 4.6: Pectin-based hybrid materials in drug delivery
- 4.7: Pectin-based composite materials in drug delivery applications
- 4.8: Conclusions
- References
- Chapter 5: Gellan gum nanoparticles in drug delivery
- Abstract
- Acknowledgments
- 5.1: Introduction
- 5.2: Gellan gum
- 5.3: Production and characterization of gellan gum nanoparticles
- 5.4: Gellan gum nanoparticles (GG nanoparticles) in drug delivery
- 5.5: Conclusions
- References
- Chapter 6: Gum kondagogu as a potential material for micro- and nanoparticulate drug delivery
- Abstract
- 6.1: Introduction
- 6.2: Modifications of gum kondagogu
- 6.3: Applications of gum kondagogu as a microparticulate and nanoparticulate carrier
- 6.4: Conclusions
- References
- Chapter 7: Gum-based nanoparticles in cancer therapy
- Abstract
- 7.1: Introduction
- 7.2: Principal natural gums in pharmaceutical applications
- 7.3: Method of preparation of GNPs
- 7.4: Characterization techniques for GNPs
- 7.5: General biomedical applications of gums
- 7.6: Gum-based nanoparticles in cancer therapy
- 7.7: Conclusions
- References
- Chapter 8: Gum-based micro- and nanobiomaterials in gene delivery
- Abstract
- 8.1: Introduction
- 8.2: Classification
- 8.3: Biomedical application of gums
- 8.4: Nonviral gene delivery
- 8.5: Natural gum-based gene delivery vectors
- 8.6: Conclusions
- References
- Chapter 9: Locust bean gum-based micro- and nanomaterials for biomedical applications
- Abstract
- 9.1: Introduction
- 9.2: Locust bean gum
- 9.3: Biodegradation of LBG
- 9.4: Bioactivity of LBG
- 9.5: Pharmaceutical applications of LBG
- 9.6: LBG microparticles
- 9.7: LBG nanoparticles
- 9.8: Conclusions
- References
- Chapter 10: Alginate microspheres: Synthesis and their biomedical applications
- Abstract
- 10.1: Introduction
- 10.2: Structure and physicochemical properties of alginates
- 10.3: Fabrication of alginate microspheres
- 10.4: Alginate microsphere and its biomedical applications
- 10.5: Conclusions
- References
- Chapter 11: Biomedical applications of cashew gum-based micro- and nanostructures
- Abstract
- 11.1: Introduction
- 11.2: Isolation and purification of cashew gum
- 11.3: Chemical composition and molecular structure of cashew gum
- 11.4: Physiochemical characteristics of cashew gum
- 11.5: Chemical modifications of cashew gum
- 11.6: Cashew gum-based microstructures
- 11.7: Cashew gum-based nanostructures
- 11.8: Conclusions
- References
- Chapter 12: Dextran-based micro- and nanobiomaterials for drug delivery and biomedical applications
- Abstract
- 12.1: Introduction
- 12.2: Application of dextrans
- 12.3: Dextran-based micro- and nanogels
- 12.4: Dextran-based electrospun nanofibers
- 12.5: Dextran-based micro- and nanoparticles
- 12.6: Concluding remarks
- References
- Chapter 13: Gum arabic-based nanocarriers for drug and bioactive compounds delivery
- Abstract
- 13.1: Introduction
- 13.2: Safety of gum arabic
- 13.3: Chemical composition and structure
- 13.4: Gum arabic: An excellent polysaccharide for encapsulation of bioactive agents
- 13.5: Different nanocarriers prepared with GA
- 13.6: Application of GA nanocarriers for various food bioactive agents
- 13.7: Conclusions and further remarks
- References
- Chapter 14: Tamarind gum as a wall material in the microencapsulation of drugs and natural products
- Abstract
- 14.1: Introduction
- 14.2: Tamarind gum characterization
- 14.3: Functional properties of tamarind gum
- 14.4: Tamarind gum-based colloidal systems in food and pharmaceutical applications
- 14.5: Tamarind gum in industrial applications
- References
- Chapter 15: Tree gum-based nanostructures and their biomedical applications
- Abstract
- Acknowledgments
- 15.1: Introduction
- 15.2: Tree gum exudates—Structure and properties
- 15.3: Nanoarchitectures based on tree gums
- 15.4: Tree gum-based NPs for biomedical applications
- 15.5: Tree gum composite nanofibers for biomedical applications
- 15.6: Tree gum-based nanostructures for drug delivery
- 15.7: Hydrogels/nanogels based on tree gums for biomedical applications
- 15.8: Conclusions
- References
- Chapter 16: Application of micro- and nanoengineering tragacanth and its water-soluble derivative in drug delivery and tissue engineering
- Abstract
- 16.1: Introduction
- 16.2: Composition and chemical structure of TG
- 16.3: Properties
- 16.4: Characterization
- 16.5: Chemical modification of TG
- 16.6: Biomedical applications
- References
- Chapter 17: Development of Persian gum-based micro- and nanocarriers for nutraceutical and drug delivery applications
- Abstract
- 17.1: Introduction
- 17.2: Medicinal applications of Amygdalus scoparia
- 17.3: Chemical composition, structure, and properties
- 17.4: Improving solubility and functionality of PG
- 17.5: Drug delivery systems
- 17.6: Other biological applications of PG
- 17.7: Concluding remarks and future trends
- References
- Chapter 18: Guar gum-based hydrogel and hydrogel nanocomposites for biomedical applications
- Abstract
- 18.1: Introduction
- 18.2: Chemistry of hydrogels
- 18.3: Synthetic routes of hydrogel
- 18.4: Polymers for hydrogel systems
- 18.5: Chemistry of guar gum
- 18.6: Applications of gg-based hydrogels
- 18.7: Guar gum-based hydrogels
- 18.8: Conclusions
- References
- Index
- Edition: 1
- Published: January 21, 2022
- No. of pages (Paperback): 514
- No. of pages (eBook): 514
- Imprint: Elsevier
- Language: English
- Paperback ISBN: 9780323909860
- eBook ISBN: 9780323909877
SJ
Sougata Jana
Dr. Sougata Jana is an Assistant Professor in the Department of Pharmaceutics at Gupta College of Technological Sciences, Asansol, India. His research focuses on the modification of synthetic and natural biopolymers, formulation development, such as oral drug delivery, transdermal drug delivery, preparation and characterization of drug-loaded microspheres, micro-particles, nanoparticles and gels, and development of interpenetrating networking systems for drug delivery.
Affiliations and expertise
Assistant Professor, Department of Pharmaceutics, Gupta College of Technological Sciences, Asansol, West Bengal, IndiaSJ
Subrata Jana
Dr. Subrata Jana is an Associate Professor in the Department of Chemistry at Indira Gandhi National Tribal University, Amarkantak, India. His research interests are molecular recognition and supramolecular chemistry, organic synthesis, medicinal chemistry, protein engineering, and enzyme catalysis.
Affiliations and expertise
Associate Professor, Department of Chemistry, Indira Gandhi National Tribal University, Amarkantak, Madhya Pradesh, IndiaRead Micro- and Nanoengineered Gum-Based Biomaterials for Drug Delivery and Biomedical Applications on ScienceDirect