Limited Offer
Save 50% on book bundles
Immediately download your ebook while waiting for your print delivery. No promo code needed.
Method Development in Analytical HPLC
- 1st Edition - November 1, 2024
- Authors: Serban C. Moldoveanu, Victor David
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 2 9 8 4 9 - 3
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 9 8 5 0 - 9
Method Development in Analytical HPLC presents the essential information for understanding the process of developing an HPLC method of analysis. It includes foundational informati… Read more
Purchase options
Institutional subscription on ScienceDirect
Request a sales quoteMethod Development in Analytical HPLC presents the essential information for understanding the process of developing an HPLC method of analysis. It includes foundational information related to HPLC, as well as discussion of sample types, the properties of analytes and matrices in the samples, and sample preparation, which is an important step in analytical methods development.
The book provides clear guidance for adopting analytical methods from the literature, informs development of original methods with selection of the suitable type of HPLC, of specific columns, mobile phase, and detection techniques with emphasis on the use of mass spectrometry for detection, as well as optimization and validation of the chosen analytical method. The book also includes useful details on method development for specific types of chromatography such as RP-HPLC, HILIC, ion exchange, size exclusion, and chiral.
Method Development in Analytical HPLC also includes information about green chemistry in analytical methods, computer assisted method development, and other key contemporary aspects of the subject.
1. Introductory concepts related to a chemical analysis
2. Retention and elution processes in HPLC
3. Instrumentation in HPLC
4. Performance and utilization of HPLC separation and detection
5. Samples for HPLC analysis
6. Sample preparation for an HPLC analysis
7. Chromatographic columns in HPLC
8. Mobile phase and the role of solvents in HPLC
9. Development of an HPLC analytical method
10. Selection of the best options in developing an HPLC analytical method
11. Method and data validation in HPLC analysis
2. Retention and elution processes in HPLC
3. Instrumentation in HPLC
4. Performance and utilization of HPLC separation and detection
5. Samples for HPLC analysis
6. Sample preparation for an HPLC analysis
7. Chromatographic columns in HPLC
8. Mobile phase and the role of solvents in HPLC
9. Development of an HPLC analytical method
10. Selection of the best options in developing an HPLC analytical method
11. Method and data validation in HPLC analysis
- No. of pages: 500
- Language: English
- Edition: 1
- Published: November 1, 2024
- Imprint: Elsevier
- Paperback ISBN: 9780443298493
- eBook ISBN: 9780443298509
SM
Serban C. Moldoveanu
Serban C. Moldoveanu was Senior Principal Scientist at R. J. Reynolds Tobacco Company, USA, and retired at the end of 2023. His research activity was focused on various aspects of chromatography including method development for the analysis by GC/MS, HPLC, and LC/MS/MS of natural products and cigarette smoke. He has also performed research on pyrolysis of a variety of polymers and small molecules. He has written over 150 publications in peer reviewed journals, eleven books, and several chapter contributions. He is a member of the editorial board of the Journal of Analytical Methods in Chemistry and of Frontiers in Chemistry.
Affiliations and expertise
Senior Principal Scientist, RJ Reynolds Tobacco Co., Winston-Salem, NC, USAVD
Victor David
Victor David was a Professor and Head of the Department of Analytical Chemistry, University of Bucharest, Romania. Recently retired, he remains Emeritus Professor at the same Department. His main field of research is separation science (theory and applications in various scientific domains). He is the author of more than 200 publications, including over 150 scientific papers in peer reviewed journals and 25 books and chapters. He is member of editorial board of Biomedical Chromatography, Molecules, Journal of Essential Oil-Bearing Plants and Revue Roumaine de Chimie.
Affiliations and expertise
Professor and Head of the Department of Analytical Chemistry, University of Bucharest, Romania