Metal Oxides for Biomedical and Biosensor Applications

1st Edition - December 3, 2021
Editor: Kunal Mondal
Language: English
Paperback ISBN:
9 7 8 - 0 - 1 2 - 8 2 3 0 3 3 - 6
eBook ISBN:
9 7 8 - 0 - 1 2 - 8 2 3 0 5 8 - 9

Metal Oxides for Biomedical and Biosensor Applications gives an in-depth overview of the emerging research in the biomedical and biosensing applications of metal oxides, including… Read more

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Metal Oxides for Biomedical and Biosensor Applications gives an in-depth overview of the emerging research in the biomedical and biosensing applications of metal oxides, including optimization of their surface and bulk properties. Sections cover biomedical applications of metal oxides for use in cell cultures, antibacterial and antimicrobial treatments, dental applications, drug delivery, cancer therapy, immunotherapy, photothermal therapy, tissue engineering, and metal oxide-based biosensor development. As advanced and biofunctionalized nano/micro structured metal oxides are finding applications in microfluidics, optical sensors, electrochemical sensors, DNA-based biosensing, imaging, diagnosis and analysis, this book provides a comprehensive update on the topic.

Additional sections cover research challenges, technology limitations, and future trends in metal oxides and their composites regarding their usage in biomedical applications.

Cover image
Title page
Table of Contents
Copyright
List of contributors
Series editor biography
Preface to the series
Section 1: Biomedical applications of metal oxides
1. Bioactivity, biocompatibility, and toxicity of metal oxides
Abstract
1.1 Introduction
1.2 Metals oxides and their biomedical applications
1.3 Bioactivity of metal oxides
1.4 Biocompatibility of metal oxide
1.5 Toxicity of metal oxides
1.6 Summary
References
Further reading
2. Drug delivery using metal oxide nanoparticles
Abstract
2.1 Introduction
2.2 Metal oxide-based nanoparticles for drug delivery and other biomedical applications
2.3 Concluding remarks and perspectives
References
3. Cancer therapy, immunotherapy, photothermal therapy
Abstract
3.1 Introduction
3.2 Cancer biology and nanoparticles
3.3 Metal oxides for cancer therapy
3.4 Iron oxides for cancer therapy
3.5 Titanium dioxides for cancer therapy
3.6 Zinc oxides for cancer therapy
3.7 Transition metal oxides for cancer therapy
3.8 Metal oxides for immunotherapy
3.9 Nanoparticles elicit immune responses by delivering targeted antigens
3.10 Cobalt oxides as immunotherapeutic agents
3.11 Hydroxides as immunotherapeutic agents
3.12 Iron oxides as immunotherapeutic agents
3.13 Graphene oxides as immunotherapeutic agents
3.14 Metal oxides for photothermal therapy
3.15 Graphene oxides as photothermal agents
3.16 Titanium dioxide as photothermal agents
3.17 Iron oxides as photothermal agents
3.18 Manganese oxides as photothermal agents
3.19 Conclusions
References
4. Metal oxides for cosmetics and sunscreens
Abstract
4.1 Introduction
4.2 Applications of metal oxides in cosmetics and sunscreens
4.3 Mechanism of dermal absorption and toxicity of metal oxides in human skin
4.4 Discussion and conclusions
References
5. Tissue engineering
Abstract
5.1 Metal oxides
5.2 Application of nanotechnology in tissue engineering
5.3 Application of metal oxides in tissue engineering
References
6. Role of light-active metal oxide-based nanohybrids in biofilm annihilation devices
Abstract
6.1 What this chapter seeks to do
6.2 Formation of bonds: molecules
6.3 Bonds to bands: solids
6.4 Nanocrystals: effects of surface and size
6.5 Nanocrystal–molecule interactions—the microscopic picture
6.6 Nanocrystal–molecule interactions—antibacterial action
6.7 Nanocrystal-molecule hybrids against biofilms
6.8 Outlook
Acknowledgment
References
Section 2: Metal oxide-based biosensors
7. Introduction to metal oxide-based biosensing
Abstract
7.1 Introduction
7.2 Synthesis strategies of metal oxides for biosensors
7.3 Microsystems biosensing devices
7.4 Conclusions and future visions
Acknowledgments
References
8. Exploring the potential of metal oxides for biomedical applications
Abstract
8.1 Introduction
8.2 Physicochemical properties of metal oxide nanoparticles
8.3 Commonly used metal oxides for biomedical applications
8.4 Conclusion and future perspectives
References
9. Surface coating and functionalization of metal and metal oxide nanoparticles for biomedical applications
Abstract
9.1 Introduction
9.2 Metal nanoparticles
9.3 Metal oxide nanoparticles
9.4 Metal and metal oxide functionalization
9.5 Metal and metal oxide nanoparticles
9.6 Conclusions
Acknowledgments
References
10. Metal oxidesbased microfluidic biosensing
Abstract
10.1 Introduction
10.2 Basics of microfluidics
10.3 Microfluidic metal oxide biosensors
10.4 Conclusion
References
11. Metal/metal oxides for electrochemical DNA biosensing
Abstract
11.1 Introduction in DNA biosensing
11.2 Fundamental properties of nanostructured metal oxides used for DNA biosensing
11.3 Size and surface particularities
11.4 Surface energy and electrical properties
11.5 Stability and reactivity
11.6 Biosensors based on DNA-functionalized nanostructured metal oxides
11.7 Metallic and semiconducting oxides used in DNA biosensing
11.8 DNA biosensors applications
11.9 Eukaryotic cells and microorganisms
11.10 DNA-based metal sensing
11.11 Conclusions and future perspectives
References
12. Metal oxides and their composites as flow-through biosensors for biomonitoring
Abstract
12.1 Introduction
12.2 Microfluidic devices
12.3 Methods for fabrication of microfluidic channels
12.4 Microfluidic and nanofluidic biosensor platforms
12.5 Biosensors: how they work? What are the benefits of biosensors in modern life?
12.6 Metal oxides and their composites in microfluidic biosensing
12.7 New advancement in microfluidic biosensors
12.8 Future perspective
References
13. Nanomaterials of metal and metal oxides for optical biosensing application
Abstract
13.1 Introduction
13.2 Optical biosensing strategies
13.3 Conclusion
Acknowledgment
References
14. Metal oxides for detection of cardiac biomarkers
Abstract
14.1 Introduction
14.2 Biomarkers for diagnosis
14.3 Future prospects and conclusion
References
Section 3: Specific metal oxides and their biomedical applications
15. Regulating cell function through micro- and nanostructured transition metal oxides
Abstract
15.1 Introduction
15.2 Cellular response to transition metal oxide micro- and nanostructures
References
16. Biomedical application of ZnO nanoscale materials
Abstract
16.1 Introduction
16.2 ZnO metal oxide
16.3 Nanostructures and the growth processes
16.4 Synthesis techniques for ZnO nanomaterials
16.5 Biomedical applications
16.6 Mechanism
16.7 Conclusion
References
17. Recent progress on titanium oxide nanostructures for biosensing applications
Abstract
17.1 Introduction
17.2 Properties of TiO2
17.3 Synthesis of TiO2 nanostructures for biosensors
17.4 Working principle of TiO2 biosensors
17.5 TiO2 biosensors
17.6 Conclusion
References
18. ZrO2 in biomedical applications
Abstract
18.1 Introduction
18.2 Applications of zirconia
References
19. Iron oxides and their prospects for biomedical applications
Abstract
19.1 Introduction: iron oxide in biomedical applications
19.2 Synthesis of iron oxide nanoparticles with respect to biomedical applications
19.3 Methods of physicochemical characterization
19.4 Methods for functionalization of metal nanoparticles for biomedical applications
19.5 Biomedical applications
19.6 Conclusion
Acknowledgments
References
20. Flexible and stretchable indium-fallium-zinc oxide-based electronic devices for sweat pH sensor application
Abstract
20.1 Overview of oxides-based electronic devices
20.2 Flexible and stretchable IGZO-based field effect transistors
20.3 Sweat pH sensor using flexible IGZO field effect transistors
20.4 Conclusion
References
21. Layered metal oxides for biomedical applications
Abstract
21.1 Introduction
21.2 Structures and polymorphs of layered metal oxides
21.3 Synthesis
21.4 Functionalization of layered metal oxides
21.5 Toxicity
21.6 Applications
21.7 Conclusion and outlook
References
22. Metal oxide/graphene nanocomposites and their biomedical applications
Abstract
22.1 Introduction
22.2 Synthesis of graphene and its derivatives
22.3 Graphene-based biosensors
22.4 Graphene-based nanocomposites for gene and drug delivery
22.5 Metal oxide-modified graphene nanostructures for antibacterial applications
22.6 Graphene-based wearable devices for biomedical applications
References
23. Liquid metal-based soft actuators and sensors for biomedical applications
Abstract
23.1 Introduction
23.2 Soft actuators
23.3 Soft sensors
23.4 Summary
References
Index

Life Sciences

Physical Sciences & Engineering

Social Sciences & Humanities

Health

Metal Oxides for Biomedical and Biosensor Applications

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Kunal Mondal