Meiosis

Preface


1 Introduction to Meiosis

I. The Basics

II. Commitment to Meiosis

III. Chromosome Pairing

IV. Recombination

References

I Evolution


2 Genetic Transmission and the Evolution of Reproduction: The Significance of Parent-Offspring Relatedness to the "Cost of Meiosis"

I. Introduction

II. The Covariance between Fitness and Genotype

III. On the Evolution of Selfing

IV. On the Evolution of Parthenogenesis

V. Summary

References


3 The Evolution of Parthenogenesis: A Historical Perspective

I. Introduction

II. Meiosis and Parthenogenesis

III. The Hybridization Hypothesis in Plants

IV. Mutations as the Source of Parthenogenesis in Animals

V. Hybridization as the Source of Parthenogenesis in Insects

VI. The Prime Case of a Hybrid Origin in Insects

VII. The Spontaneous versus Hybridization Controversy in Vertebrates

VIII. The Mechanisms of Meiotic Restitution

References

II Recombination


4 Meiotic Recombination Interpreted as Heteroduplex Correction

I. Introduction

II. The Observations

III. Heteroduplex Repair Models of Conversion

IV. Alternatives to Excision Repair of Heteroduplex

References


5 Models of Heteroduplex Formation

I. Introduction

II. Direction of Travel of the Event

III. Models of Heteroduplex Formation

IV. Control of Crossover Position by an Aviemore Process

V. Conversion and Crossing-Over as Separate Events

VI. Speculation

References


6 Investigating the Genetic Control of Biochemical Events in Meiotic Recombination

I. Introduction

II. Genetically Identifiable Factors Affecting Meiotic Recombination

III. Methods of Isolating and Characterizing Mutants

IV. Molecular and Genetic Studies of Meiotic Recombination in Yeast

V. Conclusions

References

III Chromosomes


7 Chiasmata

I. Historical and Descriptive

II. The Chiasmatype Theory

III. The Mechanism of Chiasma Formation

IV. Do Chiasmata Terminalize?

V. The Nature of "Terminal" Bivalent Associations

VI. Chiasma Variation: An Overview

VII. Indications of Chiasma Control

VIII. Genetic Control of Chiasma Distribution

IX. Models of Chiasma Control

X. Mechanisms of Chiasma Distribution Control

References


8 The Synaptonemal Complex and Meiosis: An Immunocytochemical Approach

I. Introduction

II. An Introduction to SC Biology

III. An Immunocytochemical Approach

IV. Preliminary Results

V. Summary

References


9 The Rabl Orientation: A Prelude to Synapsis

I. Introduction

II. The Rabl Orientation in Mitotic Cells

III. Meiosis and the Rabl Orientation

IV. Summary

References

IV Chemistry of Meiosis


10 The Biochemistry of Meiosis

I. Introduction

II. The Prezygotene Phase

III. The Zygotene Phase

IV. The Pachytene Phase: DNA

V. Meiosis-Specific Recombinogenic Proteins

VI. Regulation of Meiotic Events

References


11 Proteins of the Meiotic Cell Nucleus

I. Introduction

II. Methods for Studying Nuclear Proteins in Meiosis

III. Histones and HMG Proteins of Meiotic Cells

IV. Proteins of Structural Subcomponents of the Meiotic Cell Nucleus

V. Conclusions

References


12 Transcription during Meiosis

I. Introduction

II. Transcription in Mammalian Meiocytes

III. Transcription in Meiocytes of Lilium

IV. Transcription in Meiocytes of Saccharomyces cerevisiae

V. Summary and Future Prospects

References

Index