Medicinal Chemistry of Chemotherapeutic Agents

A Comprehensive Resource of Anti-infective and Anti-cancer Drugs

1st Edition - March 9, 2023
Editors: Pratap Chandra Acharya, Michio Kurosu
Language: English
Paperback ISBN:
9 7 8 - 0 - 3 2 3 - 9 0 5 7 5 - 6
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 9 0 7 0 1 - 9

Medicinal Chemistry of Chemotherapeutic Agents: A Comprehensive Resource of Anti-infective and Anti-cancer Drugs focuses on the basics and fundamentals of chemistry involved… Read more

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Medicinal Chemistry of Chemotherapeutic Agents: A Comprehensive Resource of Anti-infective and Anti-cancer Drugs focuses on the basics and fundamentals of chemistry involved in chemotherapeutic agents. Each chapter comprises distinct chemical classifications that include structure and IUPAC nomenclature, synthetic schemes and routes for each drug, mechanism of the drug action, metabolic pathway and structure–activity relationship (SAR) studies. The book covers current research focused on drug resistance and methods to overcome it, the development of newer drugs belonging to each category of the chemotherapeutic agents, molecules currently under clinical trials, and newly approved drugs, if any.

This book will be a valuable resource for academics and researchers, helping them to understand the fundamentals of the medicinal chemistry of the chemotherapeutic agents.

Pratap Chandra Acharya

Dr Pratap Chandra Acharya is presently working as Assistant Professor of Pharmaceutical Chemistry at the Department of Pharmacy, Tripura University (A Central University), Suryamaninagar, Tripura (W) India. He received his PhD in Pharmaceutical Chemistry from Panjab University, Chandigarh and M.Pharm (Pharmaceutical Chemistry) from IIT (BHU), Varanasi, India. He has more than 10 years of teaching and research experience in the field of pharmaceutical chemistry. He has been the member of various learned academic bodies such as IUPAC and APTI and has served as a reviewer to several international journals. His current research work involves various drug discovery projects for the development of anticancer drug candidates especially for colon cancer.

Affiliations and expertise

Assistant Professor, Pharmaceutical Chemistry at the Department of Pharmacy, Tripura University (A Central University), Suryamaninagar, Tripura (W), India

Michio Kurosu

Michio Kurosu has completed his Ph.D. from Osaka University, Japan and postdoctoral studies from Harvard University, Chemistry and Chemical Biology. He is a Professor of Pharmaceutical Science at University of Tennessee Health Science Center (UTHSC), USA. He has been teaching medicinal chemistry courses for pharmacy and Ph. D. students at UTHSC. He has a long-term interest in identifying new drug targets for bacterial infections and cancer chemotherapeutics. His research includes antibacterial and anticancer drug discoveries associated with Gram-negative bacteria, Mycobacterium spp., spore-forming bacteria (e.g. Clostridioides difficile), and solid cancers (e.g., pancreatic, breast, and ovarian cancers). As principal investigator on several NIH- and internally-funded programs, he has studied essential enzymes for growth of Acinetobacter baumannii, Klebsiella pneumoniae, and Mycobacterium tuberculosis, and glycosyl transferases for pancreatic and cervical cancers. He has been serving as editorial board members of several international journals and scientific reviewers of the NIH study sections.

Affiliations and expertise

Professor, Pharmaceutical Science, University of Tennessee Health Science Center (UTHSC), USA

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