Medical Biochemistry
- 5th Edition - January 3, 2018
- Latest edition
- Authors: John W. Baynes, Marek H. Dominiczak
- Language: English
Now fully revised, this acclaimed textbook efficiently links basic biochemistry with the day-to-day practice of medicine. You will learn basic science concepts and see them illu… Read more
Purchase options
Description
Description
Now fully revised, this acclaimed textbook efficiently links basic biochemistry with the day-to-day practice of medicine. You will learn basic science concepts and see them illustrated by clinical cases that describe patients you will likely encounter in your clinical training. You will also learn about the use of laboratory tests to diagnose and monitor the most important conditions. Brought to you in a thorough yet accessible manner, this new edition of Medical Biochemistry, Fifth Edition highlights the latest developments in regulatory and molecular biology, signal transduction, biochemistry and biomarkers of chronic disease, and bioinformatics and the '-omics'. It highlights the most important global medical issues: diabetes mellitus, obesity and malnutrition, cancer and atherosclerotic cardiovascular disease, and addresses the role of nutrition and exercise in medicine.
Key features
Key features
- Featuring a team of expert contributors that includes investigators involved in cutting-edge research as well as experienced clinicians, this book offers a unique combination of research and clinical practice tailored to today's integrated courses
- Read organ-focused chapters addressing the biochemistry of the bone, kidney, liver, lungs and muscle; and system-focused ones addressing the biochemistry of the immune and endocrine systems, neurochemistry and neurotransmission, and cancer
Table of contents
Table of contents
Section 1: Introduction
1. Introduction
Section 2: Molecules and Cells
2. Amino Acids and Proteins
3. Carbohydrates and Lipids
4. Membranes and Transport
Section 3: Metabolism
5. Hemoglobin and oxygen transport
6. Catalytic Proteins - Enzymes
7. Vitamins and Minerals
8. Bioenergetics and Oxidative Metabolism
9. Anaerobic metabolism of glucose carbohydrates in the red blood cell
10. The Tricarboxylic Acid Cycle
11. Oxidative Metabolism of Lipids in Liver and Muscle
12. Biosynthesis and Storage of Carbohydrates in Liver and Muscle
13. Biosynthesis and Storage of Fatty Acids
14. Biosynthesis of Cholesterol and Steroids
15. Biosynthesis and Degradation of Amino Acids
16. Biosynthesis and Degradation of Nucleotides
17. Complex Carbohydrates: Glycoproteins
18. Complex Lipids
19. The Extracellular Matrix
Section 4: Molecular Basis of Inheritance
20. Deoxyribonucleic Acid
21. Ribonucleic Acid
22. Protein Synthesis and Turnover
23. Regulation of Gene Expression: Basic Mechanisms
24. Genomics, Proteomics and Metabolomics
Section 5: Signalling and Growth
25. Membrane Receptors and Signal Transduction
26. Neurotransmitters
27. Biochemical Endocrinology
28. Cellular Homeostasis: Cell Growth and Cancer
29. Aging
Section 6: Fuels Nutrients and Minerals
30. Digestion and Absorption of Nutrients: The Gastrointestinal Tract
31. Glucose Homeostasis and Fuel Metabolism: Diabetes Mellitus
32. Nutrients and diets
33. Lipoprotein Metabolism and Atherogenesis
Section 7: Specialized Tissues and Their Function
34. The Role of Liver in Metabolism
35. Water and Electrolytes Homeostasis
36. Lung and the Regulation of Hydrogen Ion Concentration (Acid-Base Balance)
37. Muscle: Energy Metabolism and Contraction Exercise
38. Bone Metabolism and Calcium Homeostasis
39. Neurochemistry
Section 8: Blood and Immunity. Clinical Biochemistry
40. Blood and Plasma Proteins
41. Haemostasis and Thrombosis
42. Oxidative stress and inflammation
43. The Immune Response: Innate and adaptive immunity
Appendix 1: Selected Clinical laboratory reference ranges
Appendix 2: Case Studies
Product details
Product details
- Edition: 5
- Latest edition
- Published: January 3, 2018
- Language: English
About the authors
About the authors
JB
John W. Baynes
MD