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Major Problems in Developmental Biology
1st Edition - January 1, 1966
Editor: Michael Locke
eBook ISBN:9780323151139
9 7 8 - 0 - 3 2 3 - 1 5 1 1 3 - 9
Major Problems in Developmental Biology contains the proceedings of the 25th Symposium of the Society for Developmental Biology, held in Haverford, Pennsylvania, in June 1966. The… Read more
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Major Problems in Developmental Biology contains the proceedings of the 25th Symposium of the Society for Developmental Biology, held in Haverford, Pennsylvania, in June 1966. The papers explore some of the major problems in developmental biology, particularly those relating to cell differentiation, movements, and death; patterning; and intercellular regulation in plants. Organized into 11 chapters, this book begins with an overview of the growth and development of developmental biology as a scientific discipline, with emphasis on the role of the Society for Developmental Biology, and in particular its symposia, in the emergence of the field. The book then discusses the intra- and extracellular factors impinging upon the nucleus and regulating cell differentiation. Some chapters focus on the dynamics of determination in cell systems of insects, morphogenetic movements of animal cells, and patterns at the cell and tissue levels. The reader is also introduced to the correlations between protein structure and function in relation to cell dynamics and differentiation, along with the physiological, biochemical, and molecular biological aspects of intercellular regulation in plants and the role of cell surface in carcinogenesis. The book concludes by suggesting directions for research into the ontogeny of behavior. This book is a valuable source of information for developmental biologists.
Contributors and Presiding Chairman
The Growth and Development of Developmental Biology
Introduction
The State of Embryology in 1938 and 1939
The State of Some Nonembryological Areas of Biology from 1938 to 1940
Some Society Earlies
Organizers of the Symposia and Officers of the Society from 1939 to 1965
References
The Keys to Change: Factors Regulating Differentiation
Introduction
The Constancy Hypothesis
Differential Replication of DNA
Differential Release of Information: Puffing and Compacted Regions
DNA and RNA Synthesis during Oogenesis and Early Development
The Virus Susceptibility of Differentiating Cells
DNA Replication and Antibody Formation
Factors Regulating Differentiation
Conspectus
References
Dynamics of Determination
Text
References
Fields and Gradients
The Basic Terminology
The Nature of Fields
The Temporal Characteristics of Fields
The Causal Complexity of the Field
Abstractions from the Total Field Concept
Summary
References
Morphogenetic Cell Movements
Introduction
Cell Movements in Culture
Mechanism of Morphogenetic Movements
Epilogue
References
The Formation of Patterns in Development
Introduction
Patterns in Bird Feathers
Pigment Patterns in Amphibians
Bristle Patterns in Insects
Stomatal Patterns in Plant Leaves, with a Note on Drosophila Ocelli and Turing's Model
Scales, Color Patterns, and Hinges of Butterfly Wings
Appendix
Conclusions
Summary
References
Protein Structure in Relation to Cell Dynamics and Differentiation
Three-Dimensional Structure of Proteins
Protein Flexibility in Relation to Enzyme Action
Protein Flexibility in Relation to Activation Processes
Protein Flexibility in Relation to Inhibition Processes
A Mechanism for Protein Conformational Changes
Cooperative Effects
Protein Flexibility in Relation to Other Biological Processes
Protein Flexibility in the Control of Protein Synthesis
Amplification of Biological Changes
Suggestions for Mechanisms of Differentiation
References
Intercellular Regulation in Plants
Pharmacological Aspects
Physiological Aspects
Comparative Biochemical Aspects
Molecular Biological Aspects
A Look at the Past and Present
Intercellular Regulation in Plants: Short-Distance Effects
References
Cell Death in Morphogenesis
Introduction
Integration of Patterns of Growth and Death in Shaping the Vertebrate Limb
Control of the Death Program
Execution of the Death Sentence
General Conclusions
References
Fact and Theory about the Cell Surface in Carcinogenesis
Contact Inhibition
Studies of Cell Membranes
The Growth of Cells in Tissue Culture
Demonstration of "Conditioning Factor"
Conditioning of Medium by Rous Sarcoma Cells
General Discussion
Summary
References
Starting Points for Research in the Ontogeny of Behavior
Electrical Activity of Neurons during Maturation
Effects of Growth Factors and Hormones on Neuronal Maturation
Effects of Function on Neuronal Maturation
Are Neuronal Connections Predetermined during Development?
Formation of Connections between the Retina and Brain