Macromolecules Regulating Growth and Development
- 1st Edition - November 12, 2012
- Imprint: Academic Press
- Editor: Elizabeth Hay
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 6 1 2 9 7 3 - 1
- Paperback ISBN:9 7 8 - 0 - 1 2 - 4 3 3 5 6 6 - 0
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 1 5 8 8 0 - 0
Macromolecules Regulating Growth and Development documents the proceedings of the 30th Symposium of the Society for Developmental Biology, held at the University of Washington in… Read more
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Macromolecules Regulating Growth and Development documents the proceedings of the 30th Symposium of the Society for Developmental Biology, held at the University of Washington in Seattle, June 17-19, 1971. The contributions made by researchers at the symposium are organized into three parts. Part I deals with regulatory factors in the selective growth of mammalian cells. It includes papers on the role of the cell surface in growth and transformation; the epidermal growth factor; and the role in regulation of tumor growth. Part II examines the formation and organization of plant cell walls and the plasma membrane. It presents studies on the origin and growth of cell surface components; synthesis and secretion of proteins in plant cells; and lipids and membrane structure. Part III deals with the organization and expression of genetic information. The contributions in this section include organization of DNA and proteins in mammalian chromosomes; total synthesis of transfer RNA genes; and biosynthesis of bacterial ribosomes.
Contributors and Presiding Chairman
Preface
I. Regulatory Factors in the Selective Growth of Mammalian Cells
Role of the Cell Surface in Growth and Transformation
I. Introduction
II. Loss of Density-Dependent Growth Control in Transformed Cells and Cell Surface Alterations
III. Mitosis and Surface Changes during the Cell Cycle of Untransformed Cells in Culture
References
Epidermal Growth Factor: Chemical and Biological Characterization
I. Introduction
II. Chemistry of the Epidermal Growth Factor
III. Biology of the Epidermal Growth Factor
References
Tumor Angiogenesis: Role in Regulation of Tumor Growth
I. Introduction
II. Inhibition of Tumor Growth in the Absence of Angiogenesis
III. Stimulation of Capillary Proliferation by Tumor Occurs at a Distance
IV. Evidence for Humoral Transmission of Tumor Angiogenesis: Tumor Angiogenesis Factor
V. Bioassays for Tumor Angiogenesis Factor
VI. Summary
References
Hormonal Control of Oviduct Growth and Differentiation
I. Introduction
II. Estrogen-Mediated Differentiation
III. The Cell Cycle
IV. Properties of Oviduct Chromatin
V. Messenger RNA Translation
References
II. Formation and Organization of Plant Cell Walls and the Plasma Membrane
Origin and Growth of Cell Surface Components
I. Introduction
II. Origin and Growth of Cell Surface Components in Rapidly Elongating Pollen Tubes
III. Origin and Growth of the Plasma Membrane
IV. Summary
References
The Role of Hydroxyproline-Rich Proteins in the Extracellular Matrix of Plants
I. Introduction
II. Localization of Hydroxyproline
III. Chemistry of Hydroxyproline-Rich Glycoproteins
IV. Ariadne's Thread
References
Synthesis and Secretion of Proteins in Plant Cells: the Hydroxyproline-Rich Glycoprotein of the Cell Wall
I. Introduction
II. Biosynthesis of Peptidylhydroxyproline
III. Glycosylation of Peptidylhydroxyproline
IV. Secretion of the Glycoprotein
V. Characterization of Cell Wall Glycoprotein and Its Cytoplasmic Precursor
VI. Regulation of Cell Wall Protein Synthesis
References
Lipids and Membrane Structure
I. Specificity of Hydrophobic Associations in Lipoproteins
II. Amphipathic Lipids of Membranes
III. Lipid Bilayer Structure in Membranes
IV. Lipid Content of Biological Membranes
V. Specificity of Hydrocarbon Chains Associated with Amphipathic Lipids
VI. Oxidation Resistance of Membrane Lipids
VII. Lipids and Development
VIII. Membrane Models
References
III. Organization and Expression of Genetic Information
Organization of DNA and Proteins in Mammalian Chromosomes
I. Introduction
II. Observations and Interpretation
References
The Multiple Relations of tRNA to Metabolic Control
Text
References
Total Synthesis of Transfer RNA Genes
Text
Biosynthesis of Bacterial Ribosomes
Text
References
The Structural Basis of Selective Gene Expression in Eukaryotes
I. Introduction
II. The Extent of Transcription in Eukaryotic Cells
III. Chemical and Physical Properties of Chromatin
IV. Thermal Denaturation of Chromatin
V. Characterization of DNA in Fractionated Chromatin
VI. Conclusions
VII. Summary
References
Gene Manipulation: Progress and Prospects
I. Introduction
II. Progress with Microbial Systems
III. Possible Applications to Humans
IV. A Current Example
V. Nature of the Problem Posed by Gene Manipulation
VI. Steps Toward a Solution
References
Subject Index
- Edition: 1
- Published: November 12, 2012
- Imprint: Academic Press
- Language: English
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