
Macleod's Clinical Diagnosis
- 3rd Edition - August 14, 2024
- Imprint: Elsevier
- Authors: Euan Sandilands, Emma E Morrison, Andrew Merriman
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 1 2 5 0 4 - 1
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 1 2 5 0 3 - 4
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 2 5 0 5 - 8
Macleod's Clinical Diagnosis is a practical manual for evaluating and diagnosing problems based on presenting symptoms.The book covers the principles of the diagnostic pro… Read more

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Request a sales quoteMacleod's Clinical Diagnosis is a practical manual for evaluating and diagnosing problems based on presenting symptoms.
The book covers the principles of the diagnostic process, then takes the reader step-by-step through common acute medical presentations and how to interpret symptoms in context to produce a differential diagnosis. Readers will learn to interpret clinical features, examination findings and investigation results, and will build their confidence in assessing patients and identifying red flags.
Whether used as a stand-alone resource or as a companion to Macleod’s Clinical Examination, this book will prove invaluable for medical students and junior doctors as they build on their basic clinical skills theory to practice in the real world.
The book covers the principles of the diagnostic process, then takes the reader step-by-step through common acute medical presentations and how to interpret symptoms in context to produce a differential diagnosis. Readers will learn to interpret clinical features, examination findings and investigation results, and will build their confidence in assessing patients and identifying red flags.
Whether used as a stand-alone resource or as a companion to Macleod’s Clinical Examination, this book will prove invaluable for medical students and junior doctors as they build on their basic clinical skills theory to practice in the real world.
- Series of clear 'diagnostic guides' to all the common acute medical presentations that may present to the emergency department or acute medical unit
- Diagnostic flow charts in each chapter – helps the reader to follow a clear step-by-step approach to diagnosis
- Clear, succinct and logically ordered to support learning
- Includes how to recognise red flags, eliminate life-threatening conditions and generate a logical differential diagnosis
- Takes a problem-based approach to diagnostic reasoning, reflecting both modern medical and current educational practices
- Builds on the clinical skills outlined in the companion Macleod's Clinical Examination textbook
- Covers all the acute medical presentations required by the UKMLA syllabus
- Comes with an interactive eBook for easy anytime, anywhere access
- Cover Image
- Title page
- Copyright
- Contents
- Preface
- Abbreviations
- UKMLA Acute Medical Presentations and Where to Find Them
- Part 1 The Diagnostic Process
- 1 The diagnostic process
- Pattern recognition and probability analysis
- How to use the diagnostic guides
- Part 2 Assessment of Common Presenting Problems by System
- Section I Cardiorespiratory System
- 2 Shock
- Differential diagnosis
- Hypovolaemic shock
- Cardiogenic shock
- Distributive shock
- Obstructive shock
- Overview
- Step-by-step assessment
- 3 Chest pain
- Differential diagnosis
- Acute chest pain
- Acute coronary syndromes (ACS)
- Aortic dissection
- Pulmonary embolism
- Acute pericarditis
- Gastro-oesophageal disorders
- Pneumothorax
- Pneumonia
- Musculoskeletal problems
- Anxiety
- Other causes
- Intermittent chest pain
- Angina pectoris
- Gastro-oesophageal disorders
- Musculoskeletal disorders
- Asthma/COPD
- Anxiety
- Clinical tool: the ECG in acute chest pain
- Acute chest pain: step-by-step assessment
- Acute pleuritic pain: overview
- Acute pleuritic pain: step-by-step assessment
- Intermittent chest pain: overview
- Intermittent chest pain: step-by-step assessment
- Assessment of suspected angina
- 4 Dyspnoea
- Differential diagnosis
- Acute dyspnoea
- Chronic dyspnoea
- Acute dyspnoea: overview
- Acute dyspnoea: step-by-step assessment
- Assessment of acute exacerbation of COPD
- Assessment of respiratory tract infections
- Assessment of acute asthma exacerbation
- Chronic dyspnoea: overview
- Chronic dyspnoea: step-by-step assessment
- 5 Palpitation
- Differential diagnosis
- Heightened awareness of normal heartbeat
- Sinus tachycardia/↑stroke volume
- Extrasystoles
- Paroxysmal supraventricular tachycardia
- Atrial arrhythmias (atrial tachycardia, flutter and fibrillation)
- Ventricular tachycardia
- Bradyarrhythmia, such as sick sinus syndrome, intermittent AV block
- Overview
- Step-by-step assessment
- Attempt to document rhythm during symptoms
- 6 Haemoptysis
- Differential diagnosis
- Respiratory tract infections
- Lung cancer
- Pulmonary embolism
- Bronchiectasis
- Other causes
- Overview
- Step-by-step assessment
- Section II Gastrointestinal System
- 7 Abdominal pain
- Differential diagnosis
- Acute abdominal pain
- Chronic/episodic abdominal pain
- Acute abdominal pain: overview
- Acute abdominal pain: step-by-step assessment
- Acute upper abdominal pain: overview
- Acute upper abdominal pain: step-by-step assessment
- Acute lower abdominal pain: overview
- Acute lower abdominal pain: step-by-step assessment
- Chronic/relapsing abdominal pain: overview
- Chronic/relapsing abdominal pain: step-by-step assessment
- 8 Gastrointestinal haemorrhage
- Differential diagnosis
- Haematemesis
- Rectal bleeding
- Haematemesis: overview
- Haematemesis: step-by-step assessment
- Rectal bleeding: overview
- Rectal bleeding: step-by-step assessment
- 9 Diarrhoea
- Differential diagnosis
- Infectious diarrhoea
- Irritable bowel syndrome
- Drugs
- Colorectal cancer
- Inflammatory bowel disease
- Disorders causing malabsorption
- Other causes
- Acute diarrhoea: overview
- Acute diarrhoea: step-by-step assessment
- Chronic/persistent diarrhoea: overview
- Chronic/persistent diarrhoea: step-by-step assessment
- 10 Dysphagia
- Differential diagnosis
- Oropharyngeal dysphagia
- Oesophageal dysphagia (structural)
- Oesophageal dysphagia (dysmotility)
- Other, rarer causes
- Globus
- Overview
- Step-by-step assessment
- 11 Nausea and vomiting
- Differential diagnosis
- Gastroenteritis
- GI obstruction
- Gastroparesis
- Functional nausea and vomiting disorders
- Other GI tract disease
- Medications
- Hypercalcaemia
- Other metabolic disturbance
- CNS causes
- Other causes
- Acute nausea and vomiting: overview
- Acute nausea and vomiting: step-by-step assessment
- Chronic nausea and vomiting: overview
- Chronic nausea and vomiting: step-by-step assessment
- 12 Jaundice
- Differential diagnosis
- Prehepatic
- Hepatic
- Post-hepatic/biliary causes of jaundice
- Overview
- Step-by-step assessment
- Further assessment
- Further assessment of chronic liver disease
- Section III Neurological System
- 13 Headache
- Differential diagnosis
- Acute headache
- Subarachnoid haemorrhage (SAH)
- Other vascular causes of acute headache
- Meningoencephalitis
- Migraine
- Benign headache syndromes
- Subacute headache
- Acute angle-closure glaucoma
- Giant cell arteritis (GCA)
- Raised intracranial pressure
- Chronic subdural haematoma
- Sinusitis
- Hypertensive crisis
- Recurrent/chronic headache
- Cluster headache
- Tension headache
- Medication overuse headache
- Other causes
- Overview
- Step-by-step assessment
- 14 Limb weakness
- Differential diagnosis
- Stroke
- Transient ischaemic attack (TIA)
- Space-occupying lesions
- Spinal cord lesions
- Cauda equina syndrome
- Peripheral nerve lesions
- Motor neuron disease
- Other causes
- Bilateral limb weakness: overview
- Bilateral limb weakness: step-by-step assessment
- Unilateral limb weakness: overview
- Unilateral limb weakness: step-by-step assessment
- Further assessment
- Further assessment of stroke
- 15 Coma and altered consciousness
- Differential diagnosis
- CNS causes
- Metabolic causes
- Drugs/toxins
- Organ failure
- Other
- Overview
- Step-by-step assessment
- 16 Acute visual loss
- Differential diagnosis
- Keratitis
- Scleritis
- Uveitis
- Acute angle-closure glaucoma
- Vitreous haemorrhage
- Central retinal artery occlusion
- Central retinal vein occlusion
- Retinal detachment
- Optic neuritis
- Giant cell arteritis
- Stroke
- Migraine
- Overview
- Step-by-step assessment
- 17 Dizziness
- Differential diagnosis
- Disorders causing vertigo
- Disorders causing presyncope/light-headedness
- Disorders causing unsteadiness
- Other disorders causing dizziness
- Initial assessment: overview
- Initial assessment: step-by-step assessment
- Vertigo: overview
- Vertigo: step-by-step assessment
- Light-headedness/presyncope: overview
- Light-headedness/presyncope: step-by-step assessment
- Unsteadiness: overview
- Unsteadiness: step-by-step assessment
- Section IV Musculoskeletal System
- 18 Joint swelling
- Differential diagnosis
- Periarticular conditions
- Overview
- Step-by-step assessment
- 19 Low back pain
- Differential diagnosis
- Mechanical back pain
- Lumbar disc herniation
- Cauda equina syndrome
- Lumbar spine stenosis
- Vertebral trauma and fracture
- Axial spondyloarthritis
- Spinal tumour
- Spinal infections
- Other causes
- Overview
- Step-by-step assessment
- 20 Leg swelling
- Differential diagnosis
- Generalized oedema
- Local causes of oedema
- Overview
- Step-by-step assessment
- Section V Medicine of the Elderly
- 21 Confusion: delirium and dementia
- Differential diagnosis
- Delirium
- Drugs
- Metabolic/physiological disturbance
- Infection
- Intracranial causes
- Other causes
- Dementia/chronic cognitive impairment
- Common causes
- Reversible causes
- Other causes
- Confusion: overview
- Confusion: step-by-step assessment
- Delirium: overview
- Delirium: step-by-step assessment
- Delirium in patients with predisposing factors: overview
- Delirium in patients with predisposing factors: step-by-step assessment
- Confusion: further assessment
- Further assessment of hyponatraemia
- Further assessment of chronic confusion
- 22 Falls and immobility
- Differential diagnosis
- Accidental trip
- Reduced mobility secondary to chronic disorder
- Reduced mobility secondary to acute illness
- Reduced mobility secondary to medications
- Multifactorial mobility problems
- Mobility problems: overview
- Mobility problems: step-by-step assessment
- Gait abnormalities: overview
- Gait abnormalities: step-by-step assessment
- 23 Urinary incontinence
- Differential diagnosis
- Stress incontinence
- Urge incontinence
- Mixed incontinence
- Overflow incontinence
- Continuous incontinence
- Functional incontinence
- Transient incontinence
- Overview
- Step-by-step assessment
- Section VI Miscellaneous
- 24 Transient loss of consciousness: syncope and seizures
- Differential diagnosis
- Syncope
- Seizure
- Hypoglycaemia
- Functional neurological disorders (FNDs)
- Other causes
- Transient loss of consciousness: overview
- Transient loss of consciousness: step-by-step assessment
- Seizure: overview
- Seizure: step-by-step assessment
- Syncope: overview
- Syncope: step-by-step assessment
- 25 Weight loss
- Differential diagnosis
- Malignancy
- Nonmalignant GI disease
- Endocrine disorders
- Chronic disease
- Neurological disorder
- Medication
- Psychiatric
- Other
- Overview
- Step-by-step assessment
- 26 Fever
- Differential diagnosis
- Infection
- Malignancy
- Inflammatory diseases
- Drugs
- Other causes
- Overview
- Step-by-step assessment
- Further assessment
- Further assessment of pyrexia of unknown origin
- 27 Rash
- Differential diagnosis
- Erythroderma
- Severe Cutaneous Adverse Reactions (SCARs)
- Toxic epidermal necrolysis and Stevens–Johnson syndrome
- DRESS syndrome
- Acute generalized exanthematous pustulosis
- Generalized pustular psoriasis
- Urticaria/angioedema
- Eczema Herpeticum
- Pemphigus/pemphigoid
- Purpura (including vasculitis)
- Overview
- Step-by-step assessment
- 28 Poisoning
- Differential diagnosis
- Acute poisoning
- Chronic poisoning
- The sedated poisoned patient
- The stimulated poisoned patient
- 29 Acute kidney injury
- Differential diagnosis
- Prerenal causes
- Renal causes
- Postrenal causes
- Overview
- Step-by-step assessment
- Appendix
- Index
- Edition: 3
- Published: August 14, 2024
- Imprint: Elsevier
- No. of pages: 322
- Language: English
- Paperback ISBN: 9780443125041
- Paperback ISBN: 9780443125034
- eBook ISBN: 9780443125058
ES
Euan Sandilands
Affiliations and expertise
Consultant Physician, Clinical Toxicology & Acute Medicine, Royal Infirmary of Edinburgh, Honorary Clinical Senior Lecturer, University of Edinburgh, Edinburgh, UKEM
Emma E Morrison
Affiliations and expertise
Consultant Physician, Clinical Toxicology, Acute Medicine & Medicines Management, Royal Infirmary of Edinburgh, Edinburgh, ScotlandAM
Andrew Merriman
Affiliations and expertise
Specialist Registrar, Acute Medicine, Royal Infirmary of Edinburgh, Edinburgh, Scotland